کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5843649 1560838 2015 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewReceptome: Interactions between three pain-related receptors or the “Triumvirate” of cannabinoid, opioid and TRPV1 receptors
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
ReviewReceptome: Interactions between three pain-related receptors or the “Triumvirate” of cannabinoid, opioid and TRPV1 receptors
چکیده انگلیسی

A growing amount of data demonstrates the interactions between cannabinoid, opioid and the transient receptor potential (TRP) vanilloid type 1 (TRPV1) receptors. These interactions can be bidirectional, inhibitory or excitatory, acute or chronic in their nature, and arise both at the molecular level (structurally and functionally) and in physiological processes, such as pain modulation or perception. The interactions of these three pain-related receptors may also reserve important and new therapeutic applications for the treatment of chronic pain or inflammation. In this review, we summarize the main findings on the interactions between the cannabinoid, opioid and the TRPV1 receptor regarding to pain modulation.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacological Research - Volume 102, December 2015, Pages 254-263
نویسندگان
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