Protective effect of pterostilbene on testicular ischemia/reperfusion injury in rats
Keywords: کاسپاز; Antioxidant; Apoptosis; Caspases; Testicular torsion
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Effect of mitochondrial fission inhibition on C2C12 differentiation
Keywords: کاسپاز; Skeletal muscle; Mitochondrial fission; Apoptosis; Differentiation; Caspases; C2C12
Evodiamine induces extrinsic and intrinsic apoptosis of ovarian cancer cells via the mitogen-activated protein kinase/phosphatidylinositol-3-kinase/protein kinase B signaling pathways
Keywords: کاسپاز; Evodiamine; Ovarian neoplasms; Apoptosis; Caspases; Mitogen-activated protein kinase phosphatases; MAP kinase signaling system
Induction of mitochondria-dependent apoptosis in HepG2 human hepatocellular carcinoma cells by timosaponin A-III
Keywords: کاسپاز; Timosaponin A-III; Apoptosis; Caspases; IAP family proteins; Cytochrome c;
Mitochondrial permeability and toxicity of diethylhexyl and monoethylhexyl phthalates on TK6 human lymphoblasts cells
Keywords: کاسپاز; DEHP; diethylhexyl phthalate; MEHP; monoethylhexyl phthalate; DMSO; dimethyl sulfoxide; JC-1; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethylbenzimidazolocarbocyanine iodide; ROS; reactive oxygen species; FSU; fluorescence standard units; IC50; inhibit
Selection of nonapoptotic sperm by magnetic-activated cell sorting in Senegalese sole (Solea senegalensis)
Keywords: کاسپاز; Sole; MACS; Spermatozoa; YO-PRO-1; Caspases; Reactive oxygen species
Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species
Keywords: کاسپاز; Apoptosis; Baccharis scandens; Caspases; Cytotoxicity; FlavonoidsDHE, dihydroethidium; H2-DCF-DA, 2′,7′-dichlorodihydrofluorescein diacetate; IC50, 50% inhibition of cell growth; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; NAC,
Hypoxia drives apoptosis independently of p53 and metallothionein transcript levels in hemocytes of the whiteleg shrimp Litopenaeus vannamei
Keywords: کاسپاز; Hypoxia; Apoptosis; Caspases; dsRNA silencing; p53; Litopenaeus vannamei;
Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells
Keywords: کاسپاز; ophiopogonin D; G2/M arrest; apoptosis; cyclin B1; caspases; breast neoplasms; antineoplastic agents, phytogenic; in vitro;
Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53
Keywords: کاسپاز; AIF; Apoptosis; Caspases; Copper; In vitro; p53;
Apoptotic activities of cardenolide glycosides from Asclepias subulata
Keywords: کاسپاز; Cardenolide glycosides; Apoptosis; Asclepias subulata; Caspases
Anti-inflammatory properties of an isoxazole derivative - MZO-2
Keywords: کاسپاز; AFC; antibody forming cells; cFa; complete Freund's adjuvant; COX; cyclooxygenase; CsA; cyclosporine; Dex; dexamethasone; DMSO; dimethylsulfoxide; FCS; fetal calf serum; iFa; incomplete Freund's adjuvant; LPS; lipopolysaccharide; MTT; (3-[4,5-dimethylthia
The cybernetics of TNF: Old views and newer ones
Keywords: کاسپاز; Caspases; Cell death; Chronic inflammation; Endotoxin tolerance; NF-κB; TNF;
Evaluation of the cytotoxic, apoptosis inducing activity and molecular docking of spiroquinazolinone benzamide derivatives in MCF-7 breast cancer cells
Keywords: کاسپاز; Apoptosis; Survivin; Spiroquinazolinone benzamide; MCF-7 cells; 4t-CHQB; N-(4-tert-butyl-4'-oxo-1â²H-spiro[cyclohexane-1,2'-quinazoline]-3â²(4â²H)-yl)benzamide; Caspases; cysteine-aspartic proteases; IAPs; inhibitor of apoptosis proteins; XIAP; X-Linke
Hypothyroidism advances mammary involution in lactating rats through inhibition of PRL signaling and induction of LIF/STAT3 mRNAs
Keywords: کاسپاز; PRL signaling pathway; Nuclear receptors; STAT3; LIF; Caspases; Tissue remodelingprlr, Prolactin receptor mRNA; stat5a/stat5b/stat3, STAT5a/STAT5b/STAT3 mRNAs; STAT5a/b, STAT5a/b protein; socs1/socs3/cis, SOCS1/SOCS3/CIS mRNAs; lif, LIF mRNA; erα/erβ, Est
AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells
Keywords: کاسپاز; 3-MA; 3-Methyladenine; BAF; Bafilomycin A1; STS; Staurosporine; Wt; Wild type; Apoptosis; Autophagy; BH3 mimetic; Bcl-2 family; Caspases;
Compuestos citotóxicos de origen vegetal y su relación con proteÃnas inhibidoras de apoptosis (IAP)
Keywords: کاسپاز; Cáncer; Productos naturales; Apoptosis; Inhibidor de las proteÃnas de la apoptosis; Caspasas; Cancer; Natural products; Apoptosis; Inhibitor of Apoptosis Proteins; Caspases;
Synthesis of dihydrosterculic acid-based monoglucosyl diacylglycerol and its analogues and their biological evaluation
Keywords: کاسپاز; Dihydrosterculic acid; Glycolipid-1; Furukawa's reagent; Cytotoxicity; Caspases; Cell proliferation
Organ-specific alteration in caspase expression and STK3 proteolysis during the aging process
Keywords: کاسپاز; Aging; Apoptosis; Caspases; Serine/threonine kinase 3; Peripheral organs; Brain region;
Diatom-derived oxylipins induce cell death in sea urchin embryos activating caspase-8 and caspase 3/7
Keywords: کاسپاز; Apoptosis; Caspases; Diatoms; Sea urchin;
In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition
Keywords: کاسپاز; 2,3-dihydroxy-9,10-anthraquinone; Caspases; COX-2; AKT/PI3K; Molecular docking
Human eosinophils are direct targets to nanoparticles: Zinc oxide nanoparticles (ZnO) delay apoptosis and increase the production of the pro-inflammatory cytokines IL-1β and IL-8
Keywords: کاسپاز; Eosinophils; Nanoparticles; Apoptosis; Caspases; De novo protein synthesis; Cytokines;
Apigenin supplementation protects the development of dextran sulfate sodium-induced murine experimental colitis by inhibiting canonical and non-canonical inflammasome signaling pathways
Keywords: کاسپاز; Apigenin; chronic colitis; DSS; inflammasome; caspases;
Nanoemulsion-based mucosal adjuvant induces apoptosis in human epithelial cells
Keywords: کاسپاز; NE; nanoemulsion; PI; propidium iodide; PS; phosphatidylserine; XTT; cell proliferation assay kit; Caspases; Necrosis; Necroptosis; Pyroptosis; Autophagy; RPMI 2650; FaDu;
PEITC induces apoptosis of Human Brain Glioblastoma GBM8401 Cells through the extrinsic- and intrinsic -signaling pathways
Keywords: کاسپاز; PEITC; Apoptosis; Caspases; Mitochondria; Glioblastoma;
The eudesmanolide tanapsin from Tanacetum oshanahanii and its acetate induce cell death in human tumor cells through a mechanism dependent on reactive oxygen species
Keywords: کاسپاز; Apoptosis; Eudesmanolides; Cytotoxic activity; Caspases; DNA fragmentation; Poly(ADP-ribose) polymerase
Research ReportCurcumin, encapsulated in nano-sized PLGA, down-regulates nuclear factor κB (p65) and subarachnoid hemorrhage induced early brain injury in a rat model
Keywords: کاسپاز; BA; basilar artery; caspases; cysteine requiring aspartate proteases; CSF; cerebrospinal fluid; EBI; early brain injury; ET; endothelin; HRP; horseradish peroxidase; IEL; internal elastic lamina; IL-1 and -6; interleukin 1 and 6; NF-κB; nuclear factor ka
Autophagy in Huntington disease and huntingtin in autophagy
Keywords: کاسپاز; autophagy; Huntington disease; myristoylation; neurodegeneration; post-translational modifications; trafficking; therapies; caspases
Apoptotic markers and DNA damage are related to late phase of stroke: Involvement of dyslipidemia and inflammation
Keywords: کاسپاز; Stroke; Oxidative stress; Inflammation; Caspases; DNA damage; Dyslipidemia;
Collateral sensitivity to cold stress and differential BCL-2 family expression in new daunomycin-resistant lymphoblastoid cell lines
Keywords: کاسپاز; Human lymphoblastic IM-9 cells; MDR; P-glycoprotein; Collateral sensitivity; Caspases; Bcl-2;
BNIP3 promotes calcium and calpain-dependent cell death
Keywords: کاسپاز; BNIP3; Calpain; Apoptosis; Cardiac myocytes; Caspases; Heart; Mitochondrial permeability transition pore; Calcium; Hypoxia; Acidosis; Ischemia
In vitro anticancer activity of methyl caffeate isolated from Solanum torvum Swartz. fruit
Keywords: کاسپاز; Solanum torvum; Caspases; Cytochrome c; p53; Molecular docking
The palladacycle, AJ-5, exhibits anti-tumour and anti-cancer stem cell activity in breast cancer cells
Keywords: کاسپاز; BCS; breast cancer cell; ER; oestrogen receptor; CSC; cancer stem cell; FACS; fluorescence activated cell sorting; γH2AX; gamma-histone 2AX; mTOR; mammalian/mechanistic target of rapamycin; PARP; poly(ADP-ribose) polymerase; BCL-2; B-cell lymphoma-2; Bax
Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation
Keywords: کاسپاز; 3-Methyladenine (Pubmed CID 1673); Camptothecin (Pubmed CID 24360); Etoposide (Pubmed CID 36462); 7-Bromoindirubin-3-oxime (Pubmed CID 11846148); Necrostatin-1 (Pubmed CID 282833); Q-VD-OPh (Pubmed CID 11237609); 2-Phenylethynesulfonamide (Pubmed CID 3276
The mechanism of acacetin-induced apoptosis on oral squamous cell carcinoma
Keywords: کاسپاز; Acacetin; Apoptosis; Mitochondrial pathway; Caspases; MAPKs signal pathway; Cell cycles; Oral cancer;
Antiproliferative activity of rosamultic acid is associated with induction of apoptosis, cell cycle arrest, inhibition of cell migration and caspase activation in human gastric cancer (SGC-7901) cells
Keywords: کاسپاز; Gastric cancer; Apoptosis; Rosamultic acid; Cell cycle; Caspases;
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds
Keywords: کاسپاز; Apoptosis; Structure-activity relationship; Imidazo[1,2-b][1,3,4]thiadiazole; In vitro antiproliferative activity; Caspases; BJDKBAIGGISABA-UHFFFAOYSA-N; KHHAFLWDTTYKSX-UHFFFAOYSA-N; DUQUTGOFCIEJGS-UHFFFAOYSA-N; HGDQUFSDVNLDHE-UHFFFAOYSA-N;
Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptors
Keywords: کاسپاز; Copper(II) complexes; X-ray diffraction studies; Apoptosis; THP-1, U937 and PBMC cells; Caspases; Mechanism of cell death; ÎΨm; mitochondrial membrane potential; EDTA; Ethylenediaminetetraacetic acid; H2BPClNOL; (= 1-(bis-pyridin-2-ylmethyl-amino)-3-ch
Apoptotic mechanisms of the biotechnologically produced arylnaphtalene lignan justicidin B in the acute myeloid leukemia-derived cell line HL-60
Keywords: کاسپاز; Justicidin B; Cytotoxicity; Apoptosis; HL-60; Caspases
Anti-EGFR monoclonal antibody 12-93 inhibits the growth of human salivary adenocarcinoma via sub-G1 arrest and induction of apoptosis
Keywords: کاسپاز; Cyclin dependent kinases; Cyclin-dependent kinase inhibitors; Caspases; Cell death; p16INK4a and p27KIP1
Burkholderia pseudomallei infection induces the expression of apoptosis-related genes and proteins in mouse macrophages
Keywords: کاسپاز; Apoptosis-based polymerase chain reaction array; Burkholderia pseudomallei; Caspases
Inhibition of cellular proliferation and induction of apoptosis in human lung adenocarcinoma A549 cells by T-type calcium channel antagonist
Keywords: کاسپاز; T-type calcium channel; Antagonist; Human lung adenocarcinoma (A549) cells; Pancreatic cancer (MiaPaCa2) cells; Apoptosis; Cell cycle arrest; Caspases;
Isolation and prevention of calcium oxalate-induced apoptotic death and oxidative stress in MDCK cells by diosgenin
Keywords: کاسپاز; Calcium oxalate; Diosgenin; Apoptosis; Caspases
The inhibition of human T cell proliferation by the caspase inhibitor z-VAD-FMK is mediated through oxidative stress
Keywords: کاسپاز; T lymphocytes; Caspases; z-VAD-FMK; T cell activation; Oxidative stress; Thiols
Aspartame-induced apoptosis in PC12 cells
Keywords: کاسپاز; Aspartame; Apoptosis; Caspases; AIF; PC12; Cytochrome c
Antioxidants in the prevention of UVB-induced keratynocyte apoptosis
Keywords: کاسپاز; HaCaT; UVB; Antioxidants; Apoptosis; Ultrastructure; Caspases
Gene expression of pro- and anti-apoptotic proteins in rock bream (Oplegnathus fasciatus) infected with megalocytivirus (family Iridoviridae)
Keywords: کاسپاز; Rock bream iridovirus; Megalocytivirus; Apoptosis; Caspases; Inhibitor of apoptosis;
Pro-apoptotic activity of new analog of anthracyclines - WP 631 in advanced ovarian cancer cell line
Keywords: کاسپاز; WP 631; Advanced ovarian cancer cells; Apoptosis; Caspases; DNA damage;
Activation of extrinsic- and Daxx-mediated pathways in lymphoid tissue of PRRSV-infected pigs
Keywords: کاسپاز; PRRSV; Apoptosis; Caspases; Fas; Daxx; Cytokines;
Whole venom of Loxosceles similis activates caspases-3, -6, -7, and -9 in human primary skin fibroblasts
Keywords: کاسپاز; Caspases; Loxosceles similis; Venom; Apoptosis; Necrosis; Cell deathBSA, bovine serum albumin; DMEM, Dulbecco's Modified Eagle Medium; DMSO, dimethyl sulfoxide; EM, emission; EX, excitation; HFs, human fibroblasts; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-di