FOXA1 antagonizes EZH2-mediated CDKN2A repression in carcinogenesis
Keywords: FOXA1; EZH2; CDKN2A; Carcinogenesis
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CDKN2A(p16) and HRAS are frequently mutated in vulvar squamous cell carcinoma
Keywords: Vulva; Squamous cell carcinoma; Somatic mutation; CDKN2A; HRAS; Survival;
Genome-wide DNA methylation profile of leukocytes from melanoma patients with and without CDKN2A mutations
Keywords: Melanoma; DNA methylation; Leukocytes; CDKN2A; melanoma epigenetics;
Association of ANRIL polymorphism (rs1333049:C>G) with myocardial infarction and its pharmacogenomic role in hypercholesterolemia
Keywords: ANRIL; antisense non-coding RNA in the INK4 locus; MI; myocardial infarction; GWAS; genome wide association studies; CAD; coronary artery disease; LD; linkage disequilibrium; CDKN2A; cyclin dependant kinase inhibitor 2A; CDKN2B; cyclin dependant kinase in
Ocular parameters of biological ageing in HIV-infected individuals in South Africa: Relationship with chronological age and systemic biomarkers of ageing
Keywords: Telomeres; CDKN2A; Lens density; Retinal vessel calibre; HIV;
9p21 gene locus in Spitz nevi of older individuals: absence of cytogenetic and immunohistochemical findings associated with malignancy
Keywords: Spitz nevus; Spitzoid melanoma; CDKN2A; 9p21 FISH; p16 IHC
miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A
Keywords: HCC; hepatocellular carcinoma; HBx; hepatitis B virus x; miR-101; microRNA-101; DNMT3A; DNA methyltransferase 3A; UTR; untranslated region; MSP; methylation-specific PCR; TSG; tumor-suppressor gene; GSTP1; glutathione S-transferase pi 1; RASSF1; Ras assoc
A novel bisulfite-microfluidic temperature gradient capillary electrophoresis platform for highly sensitive detection of gene promotermethylation
Keywords: Microfluidic chip; Temperature gradient capillary electrophoresis (TGCE); Bisulfite; Methylation; Colorectal cancer; CDKN2A
CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non–Small-Cell Lung Cancer
Keywords: p16; CDKN2A; Inactivation; Homozygous deletion; Methylation; Lung cancer; Adenocarcinoma; Meta-analysis
RING1B ubiquitination and stability are regulated by ARF
Keywords: ARF; alternate reading frame; CDKN2A; cyclin-dependent kinase inhibitor 2A; CHX; cycloheximide; COMMD1; copper metabolism gene MURR1 domain 1; E6-AP; E6-associated protein; MDM2; mouse double minute 2; NIAM; nuclear interactor of ARF and MDM2; PcG; polyco
Detecting DNA Methylation of the BCL2, CDKN2A and NID2 Genes in Urine Using a Nested Methylation Specific Polymerase Chain Reaction Assay to Predict Bladder Cancer
Keywords: DNA methylation; urinary bladder neoplasms; polymerase chain reaction; ACTB; β-actin; BCL2; B-cell lymphoma 2; CDKN2A; cyclin dependent kinase inhibitor 2A; LMP; low malignancy potential; MSP; methylation specific polymerase chain reaction; NID2; Nidogen
Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B
Keywords: Chromosome 9p21; ANRIL; CDKN2A; CDKN2B; Atherosclerosis
Familial melanoma: Clinical factors associated with germline CDKN2A mutations according to the number of patients affected by melanoma in a family
Keywords: cutaneous melanoma; cyclin-dependent kinase inhibitor 2A mutations; family clustering; genetic testing; multiple primary melanomas; pancreatic cancer; ARF; alternative reading frames; CDKN2A; cyclin-dependent kinase inhibitor 2A; CI; confidence interval;
Dysregulated Krüppel-Like Factor 4 and Vitamin D Receptor Signaling Contribute to Progression of Hepatocellular Carcinoma
Keywords: Transcriptional Regulation; Liver Cancer Progression; 1,25-dihydroxyvitamin; Nuclear Receptor; CDH1; cadherin-1; CDKN2A; cyclin-dependent kinase inhibitor 2A; EGFP; enhanced green fluorescent protein; HCC; hepatocellular carcinoma; KLF4; Krüppel-like fac
Stem cells as the root of pancreatic ductal adenocarcinoma
Keywords: ABC; ATP binding cassette; ALDH1; Aldehyde dehydrogenase 1a1; Arx; Aristalless-related homeobox; EMT; Epithelial-to-mesenchymal transition; CAC; Centroacinar cells; CD; Cluster of differentiation; CDKN2A; Cyclin-dependent kinase inhibitor 2A; CSC; Cancer
Effectiveness and causes for failure of surveillance of CDKN2A-mutated melanoma families
Keywords: dysplastic nevus syndrome; genes; CDKN2A; melanoma; prevention and controlCI, confidence interval; LUMC, Leiden University Medical Center; OR, odds ratio
Genetic alterations in malignant melanoma
Keywords: BRAF; CDKN2A; melanoma; mutations; PTEN; RAS
Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation
Keywords: Alzheimer's disease (AD); Astrogliosis; CDKN2A; Cell-cycle; Down's syndrome (DS); GFAP; IL-6; miRNA-125b; Vimentin
Low frequency of somatic mutations in uterine sarcomas: A molecular analysis and review of the literature
Keywords: Uterine sarcomas; Mutation; EGFR; CDKN2A; KIT; RAS
p19ARFDeficiency Reduces Macrophage and Vascular Smooth Muscle Cell Apoptosis and Aggravates Atherosclerosis
Keywords: ARF; CDKN2A; atherosclerosis; apoptosis; macrophage; vascular smooth muscle cellapoE, apolipoprotein E; BMDM, bone marrow-derived macrophage; BrdU, bromodeoxyuridine; GSNO, S-nitrosoglutathione; LDL, low-density lipoprotein; SM, smooth muscle; SNP, single
Absence of methylation-dependent transcriptional silencing in TP73 irrespective of the methylation status of the CDKN2A CpG island in plasma cell neoplasia
Keywords: Multiple myeloma; Methylation; TP73; CDKN2A; Waldenström's macroglobulinemia
Identificación de alteraciones genéticas en oligodendrogliomas mediante amplificación dependiente de ligasa de múltiples sondas (MLPA) (multiple ligationdependent probe amplification)
Keywords: Oligodendrogliomas; Deleción lp/19q; MLPA; EGFR; CDKN2A; PTEN; Oligodendrogliomas; 1p/l9q deletion; MLPA; EGFR; CDKN2A; PTEN; ADN; ácido desoxirribonucleico; GAC1; repeticiones ricas en leucina del componente neuronal 2; CAMTA1; activador de la trascrip
Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling
Keywords: CDKN2A; familial melanoma; genetic counseling; prevention; sunscreen use; UV exposureMANOVA, multivariate analysis of variance; RCR, Roy's characteristic root; SD, standard deviation; SPF, sun protection factor; UVR, ultraviolet radiation
Selection criteria for genetic assessment of patients with familial melanoma
Keywords: CDKN2A; familial; genetic counseling; genetic testing; hereditary; melanoma; p16; CAN; clinically atypical nevi; CDKN2A; cyclin-dependent kinase inhibitor 2A; DN; dysplastic nevi;
Melanoma Genetics: An Update on Risk-Associated Genes
Keywords: Genetics; Melanoma; CDKN2A; Polymorphism; Germline mutations;
A comparison of CDKN2A mutation detection within the Melanoma Genetics Consortium (GenoMEL)
Keywords: CDKN2A; Melanoma; Mutation detection; Sequencing; Polymorphism; Audit; DHPLC; False negative;
CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults—An array CGH study
Keywords: ALL; Copy number; Array CGH; CDKN2A
IGFBP3 Promoter Methylation in Colorectal Cancer: Relationship with Microsatellite Instability, CpG Island Methylator Phenotype, p53
Keywords: Colon cancer; IGFBP3; methylation; CIMP; MSI; BAX; BCL2-associated X protein; CACNA1G; calcium channel; voltagedependent; T type alpha-1G subunit; CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, CIP1); CDKN2A; cyclin-dependent kinase inhibitor 2A (p16,
Combined Analysis of COX-2 and p53 Expressions Reveals Synergistic Inverse Correlations with Microsatellite Instability and CpG Island Methylator Phenotype in Colorectal Cancer
Keywords: Colon cancer; cyclooxygenase-2; DNA methylation; MethyLight; TP53; CACNA1G; calcium channel, voltage-dependent, T type α-1G subunit; CDKN2A; cyclin-dependent kinase inhibitor 2A (p16/INK4A); CIMP; CpG island methylator phenotype; COX-2; cyclooxygenase-2;
Methylation-based molecular margin analysis in hepatocellular carcinoma
Keywords: Molecular margin; Resection margin; Hepatocellular carcinoma; Methylation assay; Methylation pattern; CDKN2A; Recurrence;
Pathological characterization of Kank in renal cell carcinoma
Keywords: Renal cell carcinoma; Tumor suppressor; CDKN2A;
Recurrent Patterns of Dual RB and p53 Pathway Inactivation in Melanoma
Keywords: CDK4; CDKN2A; genetics; melanoma; p53;
Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung
Keywords: AD; lung adenocarcinoma; APC; adenomatosis polyposis coli; CALCA; calcitonin-related polypeptide α; CDH1; E-cadherin; CDKN2A; cyclin-dependent kinase inhibitor 2A; ESR1; estrogen receptor 1; ESR2; estrogen receptor 2; GSTP1; glutathione S-transferase Ï;
Perspectives on the molecular epidemiology of aerodigestive tract cancers
Keywords: ADH; alcohol dehydrogenase; APC; adenomatous polyposis coli; 5-AZA-CdR; 5-azacytidine2â²deoxycytidine; BPDE; benzo(a)pyrene diol epoxide; BRCA1; breast cancer1; CCND1; cyclin D1; CDH1; cadherin 1; CDH13; cadherin 13; CDK4; cyclin-dependent kinase 4; CDKN