Keywords: EMT; epithelial mesenchymal transition; qRT-PCR; quantitative real time polymerase chain reaction; CXCL12; C-X-C motif chemokine ligand 12; CXCR4; C-X-C chemokine receptor type 4; CK7; cytokeratin-7; CDH1; E-cadherin; CLDN4; claudin-4; HIF-1A; hypoxia ind
مقالات ISI (ترجمه نشده)
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Keywords: Vulvar cancer; HPV; TP53; CDKN2A; mTOR; NGS;
Keywords: 5-fluorouracil; imiquimod; ingenol mebutate; acitretin; American Joint Commission on Cancer; Brigham and Women's Hospital staging system; capecitabine; CDKN2A; cetuximab; chemotherapy; classification; cSCC; CT; cutaneous squamous cell carcinoma; familial
Keywords: Neuroendocrine Carcinoma; Neuroendocrine tumors; Cancer; Molecular; p53; Microsatellite Instability; APC; Adenomatous Polyposis Coli gene; ATM; Ataxia telangiectasia mutated gene; ATRX; Alpha-thalassemia mental retardation syndrome gene; CASP8; Caspase-8
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: HSIL; high-grade squamous intraepithelial lesion; SCC; squamous cell carcinomas; CIN; cervical intraepithelial neoplasia; HPV; human papillomavirus; LOH; loss of heterozygosity; GEO; Gene Expression Omnibus; DEGs; differentially expressed genes; CDKN2A; I
Keywords: ADAM; a disintegrin and metalloprotease; ADEX; aberrantly differentiated endocrine exocrine; ALDH1; aldehyde dehydrogenase 1; CAFs; cancer associated fibroblasts; CDKN2A; cyclin dependent kinase inhibitor 2A; CSC; cancer stem cell; CTC; circulating tumor
Keywords: BRAF V600E; CDKN2A; H3 K27M; IDH; integrative diagnosis; MYB; paediatric brain tumours; RELA;
Keywords: Pancreatic cancer; Angiogenesis; Vascular endothelial growth factor (VEGF); ANGPT; angiopoietin; BRAF; serine/threonine-protein kinase B-raf; CAF; cancer associated fibroblast; Cdkn2a; cyclin-dependent kinase inhibitor 2A; CI; confidence interval; CSF1R;
Keywords: genetics; genetic syndromes; inherited cancer risk; melanoma; oncogenes; skin cancer; tumor suppressor; ACD; adrenocortical dysplasia homologue; BAP1; BRCA1-associated protein-1 (ubiquitin carboxy-terminal hydrolase); CDKN2A; cyclin-dependent kinase inhib
Keywords: CDK4; CDKN2A; familial melanoma syndromes; FAMMM; melanoma genetics; mixed cancer syndromes;
Keywords: Pancreatic cancer; Genetic testing; BRCA2; CDKN2A;
Keywords: Anti-cancer therapies; Cancer attractors; Cancer stem cells; Hypoxia; Inflammation; Interactome; Metabolic modeling; Networks; Senescence; Signaling; AKT; RAC-alpha serine/threonine protein kinase; BMI1; polycomb ring finger oncogene; C/EBP; CCAAT/enhance
Keywords: 5-aza-CdR; 5-aza-2â²-deoxycytidine; AML; acute myeloid leukemia; ANRIL; antisense non-coding RNA in the INK4 locus; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A; CoREST; co-repressor for element-1-silencing transcription factor
Keywords: gerontogen; p16INK4a; CDKN2a; toxicology; senescence; biomarkers
Keywords: Endothelial cell senescence; Genetic; Vascular ageing; Age-related diseases; Stem cell; Ang II; angiotensin II; APOE; apolipoprotein E; AQP1; aquaporin 1; ASS1; argininosuccinate synthase 1; CDK2; cyclin-dependent kinase 2; CDKN2A; cyclin-dependent kinase
Keywords: AHR; aryl hydrocarbon receptor; AIP; aryl hydrocarbon receptor interacting protein; BMP-4; bone morphogenetic protein 4; CDK; cyclin-dependent kinases; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN1B; cyclin-dependent kinase inhibitor 1B; CDKN2A; cyc
Keywords: AQP1; aquaporin-1; ARCL1B; autosomal recessive, cutis laxa, type 1B; CCDC85B; coiled-coil domain containing 85B; CDKN2A; cyclin-dependent kinase inhibitor 2A; ECM; extracellular matrix; EFEMP2; EGF containing fibulin-like extracellular matrix protein 2; F
Keywords: Telomeres; CDKN2A; Lens density; Retinal vessel calibre; Corneal endothelium; Retinal nerve fibre layer; Frailty;
Keywords: AID; activation-induced cytidine deaminase; H. pylori; Helicobacter pylori; IARC; International Agency for Research on Cancer; GI; gastrointestinal; CI; confidence interval; KLF5; Krüppel-like factor 5; VCP; valosin-containing protein; OLGA; Operative Li
Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; ADAMTS9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; ARID1A; AT rich interactive domain 1A (SWI-like); AML; Acute myelocytic leukemia; ATBF1; A
Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody
Keywords: ANOVA; analysis of variance; BrdU; 5-bromo-2â²-deoxyuridine; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN2A; CDKN inhibitor 2A; CE; coefficient of error; CV; coefficient of variation; D; day; E2F1; E2F transcription factor 1; FOXM1; Forkhead box pr
Association of the 16q24.3 region gene variants rs1805007 and rs4785763 with heightened risk of melanoma in Latvian population
Keywords: ACD; adrenocortical dysplasia protein homolog gene; AFG3L1P; AFG3-like matrix AAA peptidase subunit 1 of the pseudogene; BAP1; BRCA1 associated protein-1 gene; BRAF; serine/threonine-protein kinase B-Raf; CDK4; cyclin-dependent kinase 4; CDK10; cyclin-dep
Double sword role of EZH2 in leukemia
Keywords: EZH1,2; enhancer of Zeste 1 and 2; SUZ12; suppressor of zeste 12 homolog; EED; embryonic ectoderm development; AEBP2; adipocyte enhancer-binding protein 2; RBAP46/48; retinoblastoma binding proteins 46 and 48; PRC; polycomb-repressive complex; PcG; Polyco
Cdkn2a deficiency promotes adipose tissue browning
Keywords: Obesity; Type 2 diabetes; Insulin sensitivity; Energy expenditure; cdkn2a; Genome-wide association study; Adipose tissue browning;
Eucalyptus microcorys leaf extract derived HPLC-fraction reduces the viability of MIA PaCa-2 cells by inducing apoptosis and arresting cell cycle
Keywords: 7-AAD; 7-aminoactinomycin D; ABTS; 2,2â²-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid; ANOVA; analysis of variance; ATM; ataxia telangiectasia mutated; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated protein; Bcl-2; B-cell lymphoma 2;
BAP1 loss is unusual in well-differentiated papillary mesothelioma and may predict development of malignant mesothelioma
Keywords: Well-differentiated papillary mesothelioma; BAP1; p16; CDKN2A; Single-nucleotide polymorphism genomic microarray; Malignant mesothelioma;
High CDKN2A/p16 and Low FGFR3 Expression Predict Progressive Potential of Stage pT1 Urothelial Bladder Carcinoma
Keywords: CDKN2A; mRNA; NMIBC; p16; Prognosis;
The HACD4 haplotype as a risk factor for atherosclerosis in males
Keywords: CP; carotid plaque; CAD; coronary artery disease; PCR; polymerase chain reaction; MI; myocardial infarction; Athsq1; atherosclerosis susceptibility gene locus 1; PTPLAD2; protein tyrosine phosphatase-like A domain-containing protein; HACD4; 3-hydroxyacyl-
Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times
Keywords: Pancreas; Prognosis; Prognostic Factor; Risk; ARID1A; AT-rich interaction domain 1A; ATRX; alpha-thalassemia/mental retardation X-linked; CDKN2A; cyclin dependent kinase inhibitor 2A; DAXX; death domain-associated protein; DFS; disease-free survival; DSS;
A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells
Keywords: AP4; Activating Protein 4; BAX; Bcl-2-associated X protein; Brd4; Bromodomain-containing protein 4; Brg1; Brahma-related gene-1; C2H2; Cys2-His2 zinc finger; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A gene; CDKN1A; Cyclin-Depe
Genomic analysis of adult B-ALL identifies potential markers of shorter survival
Keywords: B-cell; Acute lymphoblastic leukemia; Genome-wide association study; Copy number abnormalities; CDKN2A; IKZF1;
Original ArticlePalbociclib, a selective CDK4/6 inhibitor, enhances the effect of selumetinib in RAS-driven non-small cell lung cancer
Keywords: RAS; MEK; CDK4/6; CDKN2A; Survivin;
Reverting p53 activation after recovery of cellular stress to resume with cell cycle progression
Keywords: AMPK; AMP - activate kinase alpha 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; CHK2; checkpoint kinase 2; CHK1; checkpoint kinase 1; CDK; cyclin-dependent kinase; CDKN2A; cyclin dependent kinase inhibitor 2A;
Loss of p16INK4A Expression and Homozygous CDKN2A Deletion Are Associated with Worse Outcome and Younger Age in Thymic Carcinomas
Keywords: p16INK4A; CDKN2A; Thymic carcinoma; Fluorescence in situ hybridization;
Evaluation of non-supervised MALDI mass spectrometry imaging combined with microproteomics for glioma grade III classification
Keywords: A; Astrocytoma; ACN; Acetonitrile; ATRX; Alpha-Thalassemia/mental Retardation syndrome X-linked; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A; CGH-array; Comparative Genomic Hybridization; DNA; Deoxyribonucleic Acid; EGFR; Epidermal Growth Factor Receptor
Effects of BPA on global DNA methylation and global histone 3 lysine modifications in SH-SY5Y cells: An epigenetic mechanism linking the regulation of chromatin modifiying genes
Keywords: 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; BPA; bisphenol A; EFSA; European Food Safety Authority; H3K9ac; histone H3 lysine 9 acetylation; H3K9me3; histone H3 lysine 9 trimethylation; H3K27me3; histone H3 lysine 27 trimethylation; H3K4me3; h
Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats
Keywords: ATG; autophagy-related gene; Bak1; BCL2-antagonist/killer 1; Bcl-2; B-cell lymphoma 2; Bcl-XL; Bcl2-like 1; Beclin1; BCL2 interaction myosin/moesin like coiled-coil protein 1; Cdkn2A; cyclin-dependent kinase inhibitor 2A; Dapk1; death associated protein k
Phenotypic and Histopathological Tumor Characteristics According to CDKN2A Mutation Status among Affected Members of Melanoma Families
Keywords: CDKN2A; cyclin-dependent kinase inhibitor 2A;
Two gene polymorphisms (rs4977756 and rs11515) in CDKN2A/B and glioma risk in South Indian population
Keywords: CDKN2A; rs11515; rs4977756; Glioma; Polymorphism;
Original articleMultiple primary melanomas (MPMs) and criteria for genetic assessment: MultiMEL, a multicenter study of the Italian Melanoma Intergroup
Keywords: cyclin-dependent kinase; cyclin-dependent kinase inhibitor 2A; family history; genetic assessment; melanoma; microphthalmia-associated transcription factor; mutation; pancreatic cancer; CDK; cyclin-dependent kinase; CDKN2A; cyclin-dependent kinase inhibit
Implications of Genetic and Epigenetic Alterations of CDKN2A (p16INK4a) in Cancer
Keywords: CDKN2A; p16INK4a; Genetic alterations; Epigenetic alterations; Cancer
Prediction of clinical outcomes using the pyrolysis, gas chromatography, and differential mobility spectrometry (Py-GC-DMS) system
Keywords: bcl-1; b-cell lymphoma-isoform 1; CDK4; Cyclin dependent kinase 4; CDKN2A; cyclin dependent kinase inhibitor 2A; MIB-1; mindbomb 1; SOX-11; sry-related HMG box; IL-2Rα; interleukin-2 receptor alpha; IL-8; interleukin-8; MIP-1β; macrophage inflammatory p
Molecular pathogenesis of pancreatic ductal adenocarcinoma
Keywords: CDKN2A; driver genes; KRAS; pancreatic ductal adenocarcinoma; PanIN; SMAD4; TP53
Loss of p16 expression and copy number changes of CDKN2A in a spectrum of spitzoid melanocytic lesions
Keywords: Spitz; Melanoma; p16; CDKN2A; Fluorescence in situ hybridization; Immunohistochemistry;
Quantitative analysis of CDKN2A methylation, mRNA, and p16INK4a protein expression in children and adolescents with Burkitt lymphoma: Biological and clinical implications
Keywords: Burkitt lymphoma; CDKN2A; Methylation; p16INK4a; Pyrosequencing; Survival;
Hypermethylation in gastric cancer
Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; APC; adenomatosis polyposis coli; ATP; adenosine-triphosphate; BCL6B; B-Cell CLL/Lymphoma 6, Member B; BGS; bisulfite genomic sequencing; BMP-2; bone morphoge
Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs?
Keywords: GWAS; type 2 diabetes; cardiovascular disease; CDKN2A; CDKN2B; ANRIL
Histologic features of melanoma associated with CDKN2A genotype
Keywords: CDKN2A; classification and regression tree analysis; familial melanoma; genetic testing; histology; pagetoid scatter; pigmentation; sporadic melanoma; AJCC; American Joint Committee on Cancer; CART; classification and regression tree; MITF; microphthalmia
Transcript profile of cellular senescence-related genes in Fuchs endothelial corneal dystrophy
Keywords: Fuchs endothelial corneal dystrophy; Pathogenesis; Corneal endothelium; Cellular senescence; NOX4; CDKN2A; Oxidative stress;