Role of HIPK2 in kidney fibrosis
Keywords: سیگنالینگ سلولی; cell signaling; HIPK2; kidney fibrosis; tubular epithelial cell
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Gβγ interacts with mTOR and promotes its activation
Keywords: سیگنالینگ سلولی; Gβγ; G-protein; mTOR; AKT; G-protein coupled receptor; Raptor; Rictor; Cell signaling
The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration
Keywords: سیگنالینگ سلولی; GAP; GTPase activating protein; GGA3; golgi-localized, γ-ear-containing Arf-binding protein 3; HA; hemagglutinin; PBD; p21-binding domain; PI3K; phosphatidylinositol (3)-kinase; PIP3; phosphatidylinositol (3,4,5) trisphosphate; ARF; Rac; Cell migration;
RAF signaling in neuroendocrine neoplasms: From bench to bedside
Keywords: سیگنالینگ سلولی; RAF; RAF-1; BRAF; MAPK; Neuroendocrine tumors; Neuroendocrine neoplasms; NET; Molecular targeted therapy; Cell signaling;
sAC from aquatic organisms as a model to study the evolution of acid/base sensing
Keywords: سیگنالینگ سلولی; Cyclic AMP; Bicarbonate; Acidosis; Alkalosis; Cell signaling; Carbon Dioxide
Oxysterols act as promiscuous ligands of class-A GPCRs: In silico molecular modeling and in vitro validation
Keywords: سیگنالینگ سلولی; Oxysterols; Cell signaling; G proteins; Cholesterol; Receptors/seven transmembrane domain; Molecular recognition;
Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling
Keywords: سیگنالینگ سلولی; ANOVA; analysis of variance; CUL7; Cullin7; CRL7; Cullin RING E3 ubiquitin ligase 7; FBXW8; F-box/WD repeat-containing protein 8; GLUT4; glucose transporter 4; HSP90; heat shock protein 90; IRS; insulin receptor substrate; IGF-1; insulin-like growth hormo
Dietary nitrite improves insulin signaling through GLUT4 translocation
Keywords: سیگنالینگ سلولی; Nitric oxide; Insulin; Cell signaling; GLUT4; Diabetes; Nutrition; Free radicals;
The ABC of BTC: Structural properties and biological roles of betacellulin
Keywords: سیگنالینگ سلولی; Growth factors; Betacellulin; Epidermal growth factor receptor; Cell signaling; Diabetes; Angiogenesis; Cancer
ATP7B activity is stimulated by PKCÉ in porcine liver
Keywords: سیگنالینگ سلولی; BCS; bathocuproine disulfonate; MOPS; 3-(N-morpholino) propanesulfonic acid; PMA; phorbol 12-myristate 13-acetate; PPase λ; protein phosphatase λ; ATPases; Copper transport; Protein kinase C É (PKCÉ); Cell signaling; ATP7B;
Targeting CHK1 inhibits cell proliferation in FLT3-ITD positive acute myeloid leukemia
Keywords: سیگنالینگ سلولی; Acute myeloid leukemia; FLT3-ITD; CHK1; Cell cycle; Cell signaling; Proliferation
The role of adenosine receptors A2A and A2B signaling in renal fibrosis
Keywords: سیگنالینگ سلولی; cell signaling; chronic renal disease; fibrosis; inflammation; renal fibrosis;
Boldine induces cell cycle arrest and apoptosis in T24 human bladder cancer cell line via regulation of ERK, AKT, and GSK-3β
Keywords: سیگنالینگ سلولی; Bladder cancer; Boldine; G2/M-phase arrest; Apoptosis; Cell signaling;
The cooperative roles of the dopamine receptors, D1R and D5R, on the regulation of renal sodium transport
Keywords: سیگنالینگ سلولی; calcium; cell signaling; cyclic AMP; kidney; Na transport; renal proximal tubule cell;
Protease-mediated human smooth muscle cell proliferation by urokinase requires epidermal growth factor receptor transactivation by triple membrane signaling
Keywords: سیگنالینگ سلولی; uPA; Protease domain; Epidermal growth factor receptor; Proliferation; Cell signaling; Human coronary smooth muscle cell
Erk/MAP Kinase Signaling Pathway and Neuroendocrine Differentiation of Non–Small-Cell Lung Cancer
Keywords: سیگنالینگ سلولی; Non–small-cell lung cancer; Neuroendocrine differentiation; Cell signaling; Erk/mitogen-activated protein kinases
Original Full Length ArticleAnti-apoptotic Bcl-2 family member Mcl-1 regulates cell viability and bone-resorbing activity of osteoclasts
Keywords: سیگنالینگ سلولی; Osteoclast; Apoptosis; Bone resorption; Cell signaling; Remodeling;
Proteomic profiling of the signal crayfish Pacifastacus leniusculus egg and spermatophore
Keywords: سیگنالینگ سلولی; Arthropod; Cell defence; Cell signaling; Protease; Respiration;
Inhibition of KCa3.1 suppresses TGF-β1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways
Keywords: سیگنالینگ سلولی; MCP-1; KCa3.1; TGF-β1; Cell signaling;
CommentarySecretory phospholipase A2 enzymes as pharmacological targets for treatment of disease
Keywords: سیگنالینگ سلولی; Secretory phospholipase A2; Phospholipase A2 receptor; Nanoparticles; Liposomes; Cell signaling; Interactomes; AA; arachidonic acid; AdPLA2; adipose specific phospholipase A2; BCL-6; B cell lymphoma-6; C/EBP; CCAAT-enhancer-binding proteins; COX; cyclooxy
Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis in endothelial Nox4 transgenic mouse lines
Keywords: سیگنالینگ سلولی; Nox4; Transforming growth factor beta 1; Angiogenesis; Cell signaling; Endothelium;
Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response
Keywords: سیگنالینگ سلولی; Prostate cancer stem cell; Cell proliferation; Cell signaling; DNA damage response; Tumorigenesis
Early targets of lithium in rat kidney inner medullary collecting duct include p38 and ERK1/2
Keywords: سیگنالینگ سلولی; cell and transport physiology; cell signaling; diabetes insipidus; mass spectrometry; renal cell biology;
Decorin deficiency promotes hepatic carcinogenesis
Keywords: سیگنالینگ سلولی; SLRP; small leucine-rich proteoglycan; RTK; receptor tyrosine kinase; TA; thioacetamide; DEN; diethyl nitrosamine; HCC; hepatocellular carcinoma; Dcnâ/â; decorin null; WT; wild type; p21WAF1/CIP1; cyclin-dependent kinase inhibitor p21; AP4; transcript
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension
Keywords: سیگنالینگ سلولی; angiotensin; blood pressure; cell signaling; epithelial sodium transport; hypertension; renin-angiotensin system;
Subcellular localization of the histidine kinase receptors Sln1p, Nik1p and Chk1p in the yeast CTG clade species Candida guilliermondii
Keywords: سیگنالینگ سلولی; Histidine kinase receptors; Multistep phosphorelay; Cell signaling; Fluorescent protein; Candida guilliermondii
CMV-induced pathology: pathway and gene-gene interaction analysis
Keywords: سیگنالینگ سلولی; Salivary gland; Tumor microenvironment; Cell signaling; Pathway analysis;
Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: Focus on the role and impact of proteoglycans
Keywords: سیگنالینگ سلولی; ER; estrogen receptor; PgR; progesterone receptor; HER2/erbB2; human epidermal growth factor receptor-2; E2; estradiol; RTK; receptor tyrosine kinase; IGF-IR; insulin-like growth factor I receptor; EGFR; epidermal growth factor receptor; MAPK; mitogen act
Tools and methods for studying the Drosophila JAK/STAT pathway
Keywords: سیگنالینگ سلولی; Janus kinase (JAK); STAT; Cytokine; Drosophila; Cell signaling; Genetics;
Synergistic protein secretion by mesenchymal stromal cells seeded in 3D scaffolds and circulating leukocytes in physiological flow
Keywords: سیگنالینگ سلولی; Cell signaling; Chemotaxis; Co-culture; Fibroblast growth factor; Monocytes; Shear stress
Pleiotropy of the Drosophila JAK pathway cytokine Unpaired 3 in development and aging
Keywords: سیگنالینگ سلولی; Janus kinase; Drosophila; Unpaired; Unpaired3; Cell signaling; Eye development; Wing development; Oogenesis; Gametogenesis; Complementation;
ReviewTAM receptor tyrosine kinases: Expression, disease and oncogenesis in the central nervous system
Keywords: سیگنالینگ سلولی; Cell signaling; Alzheimer's disease; Glioblastoma; Multiple sclerosis; Developmental neurology;
Berberine alters epigenetic modifications, disrupts microtubule network, and modulates HPV-18 E6-E7 oncoproteins by targeting p53 in cervical cancer cell HeLa: A mechanistic study including molecular docking
Keywords: سیگنالینگ سلولی; Berberine (Pubchem SID_162173365); Berberine; Cervical cancer; Epigenetic modification; Cytoskeleton structures; Cell signaling; Molecular docking;
In vitro impact of five pesticides alone or in combination on human intestinal cell line Caco-2
Keywords: سیگنالینگ سلولی; Pesticide; Mixture; Caco-2; Oxidative stress; Locust control; Antioxidant; Cell signaling
Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury
Keywords: سیگنالینگ سلولی; acute kidney injury; cell signaling; cisplatin; Rictor;
Crosstalk between kinases, phosphatases and miRNAs in cancer
Keywords: سیگنالینگ سلولی; Protein tyrosine kinases; Protein tyrosine phosphatases; miRNA; Cell signaling; Cancer aggressiveness; Chemotherapy resistance;
Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: Therapeutic perspectives
Keywords: سیگنالینگ سلولی; Heart; MAPK; Cardiac diseases; Mitochondria; Cell signaling; AngII; angiotensin II; CA; constitutively active; CHIP; C terminus of Hsc70-interacting protein; CT-1; cardiotrophin-1; ÎΨmit; mitochondrial membrane potential; DN; dominant negative; ERK1/2;
Calcineurin: A poorly understood regulator of muscle mass
Keywords: سیگنالینگ سلولی; CnA; calcineurin; CnAα; α isoform of the CnA catalytic subunit; CnAββ; isoform of the CnA catalytic subunit; CsA; cyclosporine; MEF2; myocyte enhancing factor 2; NFAT; nuclear factor of activated T cells; PI3K; phosphatidylinositol 3-kinase; FOXO; For
The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action
Keywords: سیگنالینگ سلولی; ATF-4; activating transcription factor 4; CB1; cannabinoid type-1 receptor; CB2; cannabinoid type-2 receptor; CHOP; C/EBP homologous protein; ER; endoplasmic reticulum; MEF; mouse embryonic fibroblast; mTORC1; mammalian target of rapamycin complex 1; mTOR
Shear stress-induced Ang II AT1 receptor activation: G-protein dependent and independent mechanisms
Keywords: سیگنالینگ سلولی; Shear stress; Mechanotransduction; Ang II AT1 receptor; Cell signaling;
Montelukast prevents microparticle-induced inflammatory and functional alterations in human bronchial smooth muscle cells
Keywords: سیگنالینگ سلولی; Montelukast sodium (PubChem CID 23663996); Salbutamol emisulphate (PubChem CID 39859); Indomethacin (PubChem CID 3715); NS398 (PubChem CID 4553); Microparticles; Montelukast; β2-Agonists; Airway smooth muscle cell; Bronchial inflammation; Cell signaling;
Fibrin improves beta (INS-1) cell function, proliferation and survival through integrin αvβ3
Keywords: سیگنالینگ سلولی; Fibrin; Integrin; Beta cell; Cell signaling; Diabetes;
Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor
Keywords: سیگنالینگ سلولی; acute kidney injury; cell signaling; erythropoietin; inflammation; sepsis;
Intracellular signaling mechanisms associated with CD47 modified surfaces
Keywords: سیگنالینگ سلولی; Biocompatibility; Gene expression; Metalloproteinase; Cell signaling;
Rho-kinase inhibition prevents the progression of diabetic nephropathy by downregulating hypoxia-inducible factor 1α
Keywords: سیگنالینگ سلولی; cell signaling; diabetic glomerulosclerosis; diabetic nephropathy; hypoxia;
Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish
Keywords: سیگنالینگ سلولی; Left-right; Zebrafish; Nodal; Vg1; Cell signaling; Axis formation;
A deficient translocation of CD3ζ, ZAP-70 and Grb2 to lipid raft, as a hallmark of defective adaptive immune response during chronic hepatitis B infection
Keywords: سیگنالینگ سلولی; Hepatitis B; T cell; Signalosome; Lipid rafts; Cell signaling;
The role of bioactive nanofibers in enamel regeneration mediated through integrin signals acting upon C/EBPα and c-Jun
Keywords: سیگنالینگ سلولی; RGDS; Peptide amphiphile; Artificial extracellular matrix; Integrin; Cell signaling; Regenerated enamel;
Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells
Keywords: سیگنالینگ سلولی; Glyphosate; Roundup; Cell signaling; Sertoli cell; Oxidative stress; Calcium homeostasis; Cell death; Free radicals;
Differential effects of the CpG-toll-like receptor 9 axis on pregnancy outcome in nonobese diabetic mice and wild-type controls
Keywords: سیگنالینگ سلولی; Animal model; cell signaling; fetomaternal interface; immune modulation; immune tolerance;