Keywords: CHB، هپاتیت B مزمن; Stomach cancer; Liver cancer; Colorectal cancer; Risk factor; ScreeningHBV, Hepatitis B virus; HCC, hepatocellular carcinoma; CHB, chronic hepatitis B; NHIRD, National Health Insurance Research Database
مقالات ISI CHB، هپاتیت B مزمن (ترجمه نشده)
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Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; ETV, entecavir; ELISA, enzyme-linked immunosorbent assay; HBeAg, hepatitis B virus e antigen; HBsAg, hepatitis B virus surface antigen; HBV, hepatitis B virus; HBV DNA, hepatitis B virus deoxyribonucleic acid; NA, nucleoside anal
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; HCC, hepatocellular carcinoma; IFN, interferon; HBV, hepatitis B virus; PEG-IFNa-2a, peginterferon alfa-2a; OR, odds ratio; CI, confidence intervals; RCT, randomized controlled trials
New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; NUC, nucleos(t)ide analogues; PegIFN-α, pegylated-interferon-alpha; cccDNA, covalently-closed-circular DNA; siRNA or RNAi, small interfering RNA; HBV, hepatitis B virus; TLR, toll-like receptor, HCC, hepatocellular carcinoma; WHO
Association between Hypoxia-inducible Factor-1α gene polymorphisms and risk of chronic hepatitis b and hepatitis b virus-related liver cirrhosis in a Chinese population: A retrospective case–control study
Keywords: CHB، هپاتیت B مزمن; HIF-1α, Hypoxia-inducible Factor-1α; HCC, hepatocellular carcinoma; CHB, chronic hepatitis B; LC, liver cirrhosis; HCV, hepatitis C virus; SNPs, single nucleotide polymorphisms; PCR, polymerase chain reaction; HWE, Hardy–Weinberg equilibrium; ORs, odds ra
Genetic polymorphisms in Toll-like receptor 3 gene are associated with the risk of hepatitis B virus-related liver diseases in a Chinese population
Keywords: CHB، هپاتیت B مزمن; TLR3, Toll-like receptor 3; HBV, hepatitis B virus; CHB, chronic hepatitis B; LC, liver cirrhosis; HCC, hepatocellular carcinoma; PCR-RFLP, polymerase chain reaction–restriction fragment length polymorphism; HWE, Hardy–Weinberg equilibrium; ORs, odds rati
Quantitative hepatitis B surface antigen combined with hepatitis B e antigen as sustained virological response predictors during extended therapy with Peginterferon alfa-2a for hepatitis B e antigen-positive chronic hepatitis B
Keywords: CHB، هپاتیت B مزمن; HBsAg, hepatitis B surface antigen; HBeAg, hepatitis B e antigen; HBV DNA, hepatitis B virus DNA; SVR, sustained virological response; NAs, nucleo(s)tide analogues; AUC, area under curve; CHB, chronic hepatitis B; ALT, alanine aminotransferase; ORs, odds
Efficacy of entecavir treatment for up to 96 weeks in nucleoside-naive HBeAg-positive chronic hepatitis B patients with high viral load
Keywords: CHB، هپاتیت B مزمن; HBeAg, Hepatitis B e antigen; CHB, Chronic hepatitis B; HBV, Hepatitis B virus; HVL, High viral load; ETV, Entecavir; VR, Virological response; TDF, Tenofovir disoproxil fumarate; BR, Biochemical responses; SR, HBeAg seroconversion; ALT, Alanine aminotran
CpG islands of hepatitis B virus genome isolated from Chinese patients
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; xp, X promoter; cp, core promoter; sp1, preS1 promoter; sp2, preS2 promoters; ORF, open reading frame; AHB, acute hepatitis B; CHB, chronic hepatitis B; HCC, hepatocellular carcinoma; HBV–LC, HBV-associated liver cirrhosis; HBV–ACL
Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease
Keywords: CHB، هپاتیت B مزمن; AST, aspartate aminotransferase; ALT, alanine aminotransferase; BMI, body mass index; CHB, chronic hepatitis B; CHC, Chronic hepatitis C; HOMA-IR, homeostasis model assessment; HBsAg, hepatitis B surface antigen; IR, insulin resistance; NAFLD, non-alcohol
Hepatitis E Virus Superinfection and Clinical Progression in Hepatitis B Patients
Keywords: CHB، هپاتیت B مزمن; HEV, hepatitis E virus; HBV, hepatitis B virus; AHB, acute hepatitis B; CHB, chronic hepatitis B; LC, liver cirrhosis; HCC, hepatocellular carcinoma; IgG, immunoglobulin G; IgM, immunoglobulin M; ORF, open reading frame; WBC, white blood cells; RBC, red b
In vitro stimulation with HBV therapeutic vaccine candidate Nasvac activates B and T cells from chronic hepatitis B patients and healthy donors
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; APC, antigen presenting cell; DCs, dendritic cells; CHB, chronic hepatitis B; HBsAg, hepatitis B surface antigen; HBcAg, hepatitis B core antigen; CTL, cytotoxic T lymphocyte; HD, healthy donor; PBMC, peripheral blood mononuclear c
Association of IPS1 polymorphisms with peginterferon efficacy in chronic hepatitis B with HBeAg-positive in the Chinese population
Keywords: CHB، هپاتیت B مزمن; ALT, aminotransferase; CHB, chronic hepatitis B; CYP27B1, cytochrome P450, family 27, subfamily B, polypeptide 1; dsRNA, double-stranded RNA; EIF2A, eukaryotic translation initiation factor 2A; ESR, end of seroconversion response; EVR, end of virological
Response to potent anti-HBV agents in chronic hepatitis B and combined effect of HBV reverse transcriptase mutations
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; NA, nucleos(t)ide analogues; CHB, chronic hepatitis B; RT, reverse transcriptase; CVR, complete virological response; ETV, entecavir; TDF, tenofovir; RMSD, root mean square deviationHepatitis B virus; Nucleos(t)ide analogues; Rever
Aberrant expression and dysfunction of TLR2 and its soluble form in chronic HBV infection and its regulation by antiviral therapy
Keywords: CHB، هپاتیت B مزمن; ALT, alanine aminotransferase; CHB, chronic hepatitis B; CR, complete response; HBeAg, hepatitis B e antigen; HBV, hepatitis B virus; HC, healthy control; IC, inactive carrier; IFN, interferon; IL, interleukin; IT, immunotolerant; LdT, telbivudine; NCR, n
Current status of immunomodulatory therapy in chronic hepatitis B, fifty years after discovery of the virus: Search for the “magic bullet” to kill cccDNA
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; HBsAg, hepatitis B surface antigen; HCC, hepatocellular carcinoma; IFN, interferon; CHB, chronic hepatitis B; NUC, nucleos(t)ide analogues; cccDNA, covalently close circular DNA; DHBV, duck hepatitis B virus; WHV, woodchuck hepatit
Viral evolutionary changes during tenofovir treatment in a chronic hepatitis B patient with sequential nucleos(t)ide therapy
Keywords: CHB، هپاتیت B مزمن; ADV, adefovir; ALT, alanine aminotrasferase; Anti-HBe, hepatitis B virus e antibody; AST, aspartate aminotrasferase; CHB, chronic hepatitis B; CT, computed tomography; ETV, entecavir; HBsAg, hepatitis B virus surface antigen; HBV, hepatitis B virus; LAM,
Prediction of prognosis to lamivudine in patients with spontaneous reactivation of hepatitis B virus-related acute-on-chronic liver failure: Using virologic response at week 4
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; MELD scores, end-stage liver failure scores; CVR, complete virologic response; PVR, partial virologic response; ACLF, acute-on-chronic liver failure; LAM, lamivudine; ALT, alanine aminotransferase level; CHB, chronic hepatitis B; L
The E genotype of hepatitis B: Clinical and virological characteristics, and response to interferon
Keywords: CHB، هپاتیت B مزمن; HBV; E genotype; PEG-interferon; Serological response; Virological responseHBV, Hepatitis B virus; HCC, hepatocellular carcinoma; NA, nucleos(t)ide analogues; CHB, chronic hepatitis B; PEG-INF, pegylated interferon; HBsAg, hepatitis B surface antigen; ALT
Efficacy of 2 years of entecavir plus adefovir therapy in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analog treatment
Keywords: CHB، هپاتیت B مزمن; ADV, adefovir dipivoxil; ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CHB, chronic hepatitis B; CK, creatine kinase; Cr, creatinine; Cys C, cystatin C; ETV, entecavir; GLB, globulin; HAV, hepatiti
Comparison of the Abbott RealTime HBV assay with the Roche Cobas AmpliPrep/Cobas TaqMan HBV assay for HBV DNA detection and quantification
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; CHB, chronic hepatitis B; HCC, hepatocellular carcinoma; PCR, polymerase chain reaction; TaqMan assay, Cobas AmpliPrep/Cobas TaqMan HBV assay; RealTime assay, Abbott RealTime HBV; HBsAg, hepatitis B surface antigen; HBeAg, hepatiti
Predictive value of interferon-gamma inducible protein 10 kD for hepatitis B e antigen clearance and hepatitis B surface antigen decline during pegylated interferon alpha therapy in chronic hepatitis B patients
Keywords: CHB، هپاتیت B مزمن; ACLF, acute-on-chronic liver failure; ALT, alanine aminotransferase; AsC, asymptomatic hepatitis B virus carriers; CHB, chronic hepatitis B; CI, confidence interval; GAPDH, glyceraldehydes 3-phosphate dehydrogenase; HAI, histological activity index; HBeAg
Role of IL28-B polymorphisms in the treatment of chronic hepatitis B HBeAg-negative patients with peginterferon
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; NA, nucleos(t)ide analogues; CHB, chronic hepatitis B; PEG-INF, pegylated interferon; HBsAg, hepatitis B surface antigen; ALT, alanine aminotransferase; HBeAg, hepatitis e antigen; SVR, sustained viro
Different mechanism of selection of adefovir-resistant mutant viruses during adefovir monotherapy in patients with lamivudine-resistant chronic hepatitis B
Keywords: CHB، هپاتیت B مزمن; LMV, lamivudine; NA, nucleos(t)ide analogue; CHB, chronic hepatitis B; HBV, hepatitis B virus; ADV, adefovir; HBsAg, hepatitis B surface antigen; anti-HBs, hepatitis B surface antibody; HBeAg, hepatitis B e antigen; anti-HBe, hepatitis B e antibody; ALT,
Early serum hepatitis B virus large surface protein level: A stronger predictor of virological response to peginterferon alfa-2a than that to entecavir in HBeAg-positive patients with chronic hepatitis B
Keywords: CHB، هپاتیت B مزمن; LHBs, hepatitis B virus large surface protein; HBsAg, hepatitis B surface antigen; HBeAg, hepatitis B e antigen; VR, virological response; SR, serological response; HBV, hepatitis B virus; CHB, chronic hepatitis B; ALT, alanine aminotransferase; ROC, rece
Ethanol potentiates hepatitis B virus replication through oxidative stress-dependent and -independent transcriptional activation
Keywords: CHB، هپاتیت B مزمن; ADH, acetaldehyde; cccDNA, covalently closed circular DNA; CHB, chronic hepatitis B; CYP2E1, cytochrome p450 2E1; DCFDA, dichlorofluoresceindiacetate; FBS, fetal bovine serum; FXR, farnesoid X receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GSH
Clinical significance of serum HBsAg levels and association with liver histology in HBeAg positive chronic hepatitis B
Keywords: CHB، هپاتیت B مزمن; HBsAg, hepatitis B surface antigen; HBeAg, hepatitis B e antigen; HBV, hepatitis B virus; BCP, basal core promoter; CHB, chronic hepatitis B; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ULN, upper limit of normal range; cccDNA, covalen
Increased Th17 cells and interleukin-17 contribute to immune activation and disease aggravation in patients with chronic hepatitis B virus infection
Keywords: CHB، هپاتیت B مزمن; ACLF, acute-on-chronic liver failure; ALT, alanine aminotransferase; HBV, hepatitis B virus; CHB, chronic hepatitis B; ELISA, enzyme-linked immunosorbent assay; FCS, fetal calf serum; IL-6, interleukin-6; IL-17, interleukin-17; IL-23, interleukin-23; IFN-
Blocking the Natural Killer Cell Inhibitory Receptor NKG2A Increases Activity of Human Natural Killer Cells and Clears Hepatitis B Virus Infection in Mice
Keywords: CHB، هپاتیت B مزمن; Liver Disease; Hydrodynamic Injection; IL-10; CirrhosisBrdU, 5-bromo-2′-deoxyuridine; CHB, chronic hepatitis B; HBcAg, hepatitis B core antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; IL, interleukin; mAb, monoclonal antibody; NK, nat
Accuracy of Risk Scores for Patients With Chronic Hepatitis B Receiving Entecavir Treatment
Keywords: CHB، هپاتیت B مزمن; Cirrhosis; Entecavir; Hepatocellular Carcinoma; Risk ScoresAUC, area under the receiver operating characteristic curve; ALT, alanine aminotransferase; CHB, chronic hepatitis B; CI, confidence interval; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surf
Comparison of LecT-Hepa and FibroScan for assessment of liver fibrosis in hepatitis B virus infected patients with different ALT levels
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; CHB, chronic hepatitis B; PLT, platelet count; AGP, α1-acid glycoprotein; LSM, liver stiffness measurement; LC, liver cirrhosis; non-LC, non-cirrhosis; DSA, Datura stramonium agglutinin; MAL, Maackia amurensis lectin; AOL, Aspergil
High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury
Keywords: CHB، هپاتیت B مزمن; HMGB1, high-mobility group box1; ACLF, acute-on-chronic liver failure; ConA, concanavalin A; PBMCs, peripheral blood mononuclear cells; TNF, tumor necrosis factor; IL, interleukin; IFN, interferon; HBV, hepatitis B virus; CHB, chronic hepatitis B; PTA, pr
Characterization of hepatitis virus B isolated from a multi-drug refractory patient
Keywords: CHB، هپاتیت B مزمن; ADV, adefovir; BCP, basic core promoter; CHB, chronic hepatitis B; ETV, entecavir; LAM, lamivudine; NAs, nucleoside analogues; RT, reverse transcriptaseHepatitis B virus; Drug resistance; Mutation; Genome
Prediction on liver fibrosis using different APRI thresholds when patient age is a categorical marker in patients with chronic hepatitis B
Keywords: CHB، هپاتیت B مزمن; HBV, Hepatitis B virus; CHB, Chronic hepatitis B; HCC, Hepatocellular carcinoma; PLT, Platelet; ASPRI, Age-spleen-PLT ratio index; APRI, Aspartate aminotransferase (AST)-to-PLT ratio index; HBsAg, Hepatitis B surface antigen; CHC, Chronic hepatitis C; HE,
Direct tissue analysis by MALDI-TOF mass spectrometry in human hepatocellular carcinoma
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; HCC, hepatocellular carcinoma; QC, QuickClassifier; SOM, self-organizing map; TNM, tumor-node-metastasisHepatocellular carcinoma; Imaging; MALDI; Proteomics; Tumor margins
Evolutionary pattern of full hepatitis B virus genome during sequential nucleos(t)ide analog therapy
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; HBV, hepatitis B virus; NUC, nucleos(t)ide analog; RT, reverse transcriptase; LAM, lamivudine; ADV, adefovir dipivoxil; LDT, telbivudine; ETV, entecavir; ALT, alanine amino transferase; ORF, open reading frame; HBeAg, hepatitis B
Three-Year Efficacy and Safety of Tenofovir Disoproxil Fumarate Treatment for Chronic Hepatitis B
Keywords: CHB، هپاتیت B مزمن; Liver Disease; Virology; Drug Resistance; Viral Replication; NucleotideADV, adefovir dipivoxil; AE, adverse event; ALT, alanine aminotransferase; CHB, chronic hepatitis B; FTC, emtricitabine; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antige
Skewed ratios between CD3+ T cells and monocytes are associated with poor prognosis in patients with HBV-related acute-on-chronic liver failure
Keywords: CHB، هپاتیت B مزمن; ACLF, acute-on-chronic liver failure; ALT, alanine aminotransferase; CHB, chronic hepatitis B; DBil, direct bilirubin; HBV, hepatitis B virus; HC, healthy control; LIL, liver-infiltrating lymphocytes; LPS, lipopolysaccharide; MELD, model for end-stage liv
Characterization of potential antiviral resistance mutations in hepatitis B virus reverse transcriptase sequences in treatment-naïve Chinese patients
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; NAs, nucleos(t)ide analogues; LMV, lamivudine; ADV, adefovir-dipivoxil; ETV, entecavir; LdT, telbivudine; RT, reverse transcriptase; AA, amino acid; NAr, nucleos(t)ide analogue resistance; CHB, chronic hepatitis B; TNF, tenofovir d
Autologus dendritic cell vaccine for chronic hepatitis B carriers: A pilot, open label, clinical trial in human volunteers
Keywords: CHB، هپاتیت B مزمن; ADC, autologous dendritic cells; ALT, alanine aminotransferase; APC, antigen-presenting cells; CHB, chronic hepatitis B; CLT, cytotoxic T lymphocyte; CR, complete response; DC, dendritic cell; DMSO, dimethyl sulfoxide; DNA, deoxyribonucleic acid; FACS, fl
Screening and Early Treatment of Migrants for Chronic Hepatitis B Virus Infection Is Cost-Effective
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; GP, general practitioner; ICER, incremental cost-effectiveness ratio; MPHS, Municipal Public Health Service; QALYs, quality-adjusted life-years
Down-regulation of Z39Ig on macrophages by IFN-γ in patients with chronic HBV infection
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; CHB, chronic hepatitis B; PBMC, peripheral blood mononuclear cell; MDM, monocyte-derived macrophage; CTL, cytotoxic T lymphocyte.Z39Ig; IFN-γ; HBV; B7 family; Macrophage
CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA
Keywords: CHB، هپاتیت B مزمن; aa, amino acid(s); ASCs, asymptomatic carriers; BCP, basal core promoter; cc, correlation coefficient; CHB, chronic hepatitis B; CTL, Cytotoxic T lymphocyte; e-CHB, HBeAg-negative CHB; HBc, hepatitis B core; HBcAg, hepatitis B core antigen; HBeAg, hepatit
Predictive Factors for Early HBeAg Seroconversion in Acute Exacerbation of Patients With HBeAg-Positive Chronic Hepatitis B
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; ULN, upper limit of normal
HBsAg Seroclearance in Chronic Hepatitis B in Asian Patients: Replicative Level and Risk of Hepatocellular Carcinoma
Keywords: CHB، هپاتیت B مزمن; cccDNA, covalently closed circular DNA; CHB, chronic hepatitis B
Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis
Keywords: CHB، هپاتیت B مزمن; BMI, body mass index; CHB, chronic hepatitis B; CHC, chronic hepatitis C; HBV, hepatitis B virus; HCV, hepatitis C virus; HOMA-IR, Homeostasis Model for Assessment of Insulin Resistance; IR, insulin resistance
PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
Keywords: CHB، هپاتیت B مزمن; AHB, acute hepatitis B; CHB, chronic hepatitis B; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FCS, fetal calf serum; PD-1, programmed death-1; PD-L1, PD-1 ligand-1; PD-L2, PD-1 ligand-2; LAM, lamivudine; ALT, alanine aminotransferas
Personalized therapy in chronic viral hepatitis
Keywords: CHB، هپاتیت B مزمن; HBV, hepatitis B virus; HCV, hepatitis C virus; HBV-DNA, hepatitis B virus genome; CHB, chronic hepatitis B; HBeAg, hepatitis B e antigen; anti-HBe, antibody against HBeAg; NUC, nucleos(t)ide analog compound; Pol/Rt gene, polymerase-reverse transcriptase
Hepatitis B virus mutations associated with in situ expression of hepatitis B core antigen, viral load and prognosis in chronic hepatitis B patients
Keywords: CHB، هپاتیت B مزمن; Hepatitis B virus; Mutation; Prognosis; Antigen; QuantificationHBV, hepatitis B virus; CHB, chronic hepatitis B; HCC, hepatocellular carcinoma; HBsAg, hepatitis B virus surface antigen; HBcAg, hepatitis B virus core antigen; HBeAg, hepatitis B e antigen;
Assessing routine and serum markers of liver fibrosis in CHB patients using parallel and serial interpretation
Keywords: CHB، هپاتیت B مزمن; CHB, chronic hepatitis B; ROC curve, receiver operating characteristic; AUROC, the areas under the ROC curves; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ–glutamyltransferase; ALP, alkaline phosphatase; TP, total protein; ALBG,