Keywords: ژنتیک شیمیایی; Lipogenesis; Chemical genetics; Cancer therapy; Fatty acid synthase; Acetyl-CoA carboxylase; Lipid metabolism;
مقالات ISI ژنتیک شیمیایی (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: ژنتیک شیمیایی; TAG; Triacylglycerol; HTS; high throughput screening; G3P; glycerol-3-phosphate; GPAT; acyl-CoA:glycerol-3-phosphate acyltransferase; LPA; lysophosphatidic acid; LPAAT; acyl-CoA:lysophosphatidic acid acyltransferase; PA; phosphatidic acid; PAP; Phosphatid
Keywords: ژنتیک شیمیایی; Chemical genetics; Mass spectrometry; Malaria; Phosphoproteome; Phosphorylation; Plasmodium; Protein kinase; Proteome; Parasite
Keywords: ژنتیک شیمیایی; Phytotoxic compound; Herbicide; Mode of action; Mechanism of action; Chemical genetics;
Interrogation of ethnomedicinal plants for synthetic lethality effects in combination with deficiency in the DNA repair endonuclease RAD1 using a yeast cell-based assay
Keywords: ژنتیک شیمیایی; NER; Nucleotide excision repair; BER; base excision repair; AO; acridine orange; Ethnomedicinal plants; Colorectal cancer; Synthetic lethality; Chemical genetics; Yeast;
N,N-Bis(glycityl)amines as anti-cancer drugs
Keywords: ژنتیک شیمیایی; Anti-cancer; Synthesis; Carbohydrate; Amine; Chemical genetics
Selective inhibition of PARP10 using a chemical genetics strategy
Keywords: ژنتیک شیمیایی; PARPs; Chemical genetics; ADP-ribosylation; Click chemistry;
Rootin, a compound that inhibits root development through modulating PIN-mediated auxin distribution
Keywords: ژنتیک شیمیایی; ABA; abscisic acid; BR; brassinosteroid; CK; cytokinin; GA; gibberellic acid; RAM; root apical meristem; SL; strigolactone; QC; quiescent center; Abundance of PIN proteins; Auxin transporters; Chemical genetics; Root development;
Discovery of small molecule inhibitors of xyloglucan endotransglucosylase (XET) activity by high-throughput screening
Keywords: ژنتیک شیمیایی; IC50; concentration required for 50% inhibition (e.g. of XET); SR; sulphorhodamine; XET; xyloglucan endotransglucosylase (activity); XGO; xyloglucan oligosaccharide; XTH; xyloglucan endotransglucosylase/hydrolase (protein); XLLG; non-fucosylated xylogluca
TR-DB: An open-access database of compounds affecting the ethylene-induced triple response in Arabidopsis
Keywords: ژنتیک شیمیایی; 1-aminocyclopropane-1-carboxylic acid (ACC); Chemical genetics; Database; Ethylene; High throughput phenotypic screen; Triple response; Arabidopsis
Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors
Keywords: ژنتیک شیمیایی; Hepatitis C virus (HCV); Chemical genetics; HCV replication inhibitors; Indole derivatives; Structure–activity relationship (SAR) study; NS5B RNA polymerase inhibitor
A chemical genetics approach reveals a role of brassinolide and cellulose synthase in hypocotyl elongation of etiolated Arabidopsis seedlings
Keywords: ژنتیک شیمیایی; ACC synthase; Acsinones; CESA6; Chemical genetics; DET2; ETO1;
Turning the switch: using chemical genetics to elucidate protein kinase functions in filamentous fungi
Keywords: ژنتیک شیمیایی; Analog-sensitive; Chemical genetics; Gatekeeper mutation; Kinase
Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae
Keywords: ژنتیک شیمیایی; HIP; haploinsufficiency profiling; HOP; homozygous deletion profiling; MDR; multidrug resistance; PDR; pleiotropic drug resistance; PelA; peloruside A; Peloruside; Paclitaxel; Chemical genetics; Yeast; MAD2; Saccharomyces cerevisiae;
Target identification of bioactive compounds
Keywords: ژنتیک شیمیایی; Target identification; Bioactive compounds; Protein function; Chemical genetics;
Design, synthesis, and biological activity of novel Magmas inhibitors
Keywords: ژنتیک شیمیایی; Magmas inhibitors; Guanidine pharmacophores; Chemical genetics; LRD-limited; Rational design; Molecular modeling; Tim16; Pam16; Mitochondrial protein import
Elucidating the functionality of kinesins: An overview of small molecule inhibitors
Keywords: ژنتیک شیمیایی; AMP-PCP; 5â²-adenylyl (beta, gamma-methylene)diphosphonate; AMP-PNP; adenylyl-imidodiphosphate; AS; adociasulfate; CENP-E; centromere-associated protein-E; DPC-4; deleted in pancreas cancer locus 4; Hklp2; human kinesin-like protein 2; HSET; human spleen
Iodine scanning of a phenazine inhibitor of vacuolar sorting
Keywords: ژنتیک شیمیایی; Chemical genetics; Target identification; Gravitropism
The activation of p38alpha, and not p38beta, mitogen-activated protein kinase is required for ischemic preconditioning
Keywords: ژنتیک شیمیایی; βKO; p38β knock-out; I/R%; myocardial infarction as a percentage of myocardium at risk of infarction; DRα; drug-resistant p38α; DRβ; drug-resistant p38β; HSP27; heat stress protein of 27 kDa; MAPK; mitogen-activated protein kinase; MAPKK; mitogen-a
Rosuvastatin, Identified From a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer
Keywords: ژنتیک شیمیایی; Angiogenesis inhibitors; Chemical genetics; Prostatic neoplasms; Rosuvastatin; Zebrafish
Dissecting the DNA damage response using functional genomics approaches in S. cerevisiae
Keywords: ژنتیک شیمیایی; DNA damage; DNA depair; DNA replication; Functional genomics; Chemical genetics
Carbohydrate scaffolds in chemical genetic studies
Keywords: ژنتیک شیمیایی; Chemical genetics; Glycomimetics; Combinatorial library; Akt; NMR
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells
Keywords: ژنتیک شیمیایی; PDK1; PKB/Akt; PI3K; Chemical genetics; AGC kinases; Apoptosis; Teratoma; Phosphorylation; BX-795; 1-NM-PP1
Enhanced selectivity for inhibition of analog-sensitive protein kinases through scaffold optimization
Keywords: ژنتیک شیمیایی; Chemical genetics; Protein kinase inhibitor; Purine scaffold;
Dissecting yeast Hog1 MAP kinase pathway using a chemical genetic approach
Keywords: ژنتیک شیمیایی; MAP kinase; Chemical genetics; Two-dimensional electrophoresis; Osmotic stress; Hog1; Direct substrate; Mass spectrometry
Small molecule screening in the zebrafish
Keywords: ژنتیک شیمیایی; Zebrafish; Embryos; Chemical genetics; Small molecule; Drug screen
The impact of genomics on discovering drugs against infectious diseases
Keywords: ژنتیک شیمیایی; Systems biology; Genome sequencing; Chemical genetics; Drug targetMOA, mode of action
Wortmannin induces zebrafish cardia bifida through a mechanism independent of phosphoinositide 3-kinase and myosin light chain kinase
Keywords: ژنتیک شیمیایی; Cardia bifida; Zebrafish; Wortmannin; Chemical genetics;
Studying phospholipid metabolism using yeast systematic and chemical genetics
Keywords: ژنتیک شیمیایی; Synthetic lethality; Chemical genetics; Saccharomyces cerevisiae; Yeast; Robotics; Phospholipid; Lipid; Metabolism;
Phenotype-first screening for the identification of novel drug targets
Keywords: ژنتیک شیمیایی; Drug Discovery; Pharmaceutical Science; Biochemistry; Chemical Biology; Genetics; Mutagenesis; Model organisms; Chemical genetics; RNAi;
Small molecule approach to studying protein tyrosine phosphatase
Keywords: ژنتیک شیمیایی; Protein tyrosine phosphatases (PTPs); Chemical genetics; Solid phase peptide synthesis (SPPS); High throughput screening (HTS); PTP1B inhibitor; Library-based parallel synthesis; Insulin signaling; Metabolic and mitogenic effect;