کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1980802 1061881 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dissecting the DNA damage response using functional genomics approaches in S. cerevisiae
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Dissecting the DNA damage response using functional genomics approaches in S. cerevisiae
چکیده انگلیسی

The faithful transmission of genetic information from a mother to daughter cells can only occur if the integrity of the genome is preserved. DNA transactions within cells are tightly regulated to prevent DNA damage. When events that challenge genome integrity do occur, a complex web of DNA damage response pathways comes into play. Studies in model organisms have contributed significantly to the understanding of these pathways. In the last decade, the development of functional genomics techniques in S.cerevisiae has ushered in systematic approaches for the study of complex cellular processes. These methods have enabled the systematic interrogation of the DNA damage response.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: DNA Repair - Volume 8, Issue 9, 2 September 2009, Pages 1110–1117
نویسندگان
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