Keywords: CHX، cycloheximide; ARCI, autosomal recessive congenital ichthyosis; ATGL, adipose triglyceride lipase; BAT, brown adipose tissue; CBs, collodion babies; CHX, cycloheximide; CIE, congenital ichthyosiform erythroderma; CM, cardiac muscle; CMA, chaperone-mediated autophagy; DM
مقالات ISI CHX، cycloheximide (ترجمه نشده)
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Keywords: CHX، cycloheximide; FRET, fluorescence energy transfer; ACSF, artificial cerebrospinal fluid; TNFα, tumor necrosis factor-α; CHX, cycloheximide; DMSO, dimethyl sulfoxidePropofol anesthesia; Caspase-3; FRET; SCAT3; Neonatal mouse
Keywords: CHX، cycloheximide; Act. D, actinomycin D; BR, bilirubin; BV, biliverdin; CHX, cycloheximide; CO, carbon monoxide; COX-2, cyclooxygenase-2; ERK1/2, extracellular signal regulated protein kinase 1/2; Fe2 +, ferrous iron; HO-1, heme oxygenase-1; IκB, inhibitory κB; IL-6, inte
Keywords: CHX، cycloheximide; AQP, aquaporin; CHX, cycloheximide; DTR, decreased transpiration rate; TR, transpiration rate; VPD, vapor pressure deficitAquaporin inhibitors; Drought; Genetic screen; Maize; Silver; Transpiration
Keywords: CHX، cycloheximide; BLI, bioluminescence imaging; CHX, cycloheximide; EGFP, enhanced green fluorescent protein; HIF, hypoxia-inducible factor; HRE, hypoxia-response element; Luc, luciferase; ODD, oxygen-dependent degradation domain; RFP, red fluorescent protein
Keywords: CHX، cycloheximide; Free sialic acid; Lysosomal storage disorder; Neurodegenerative disorders; Newborn screening; SLC17A5 genecDNA, DNA complementary to RNA; CHX, cycloheximide; DBS, dried blood spots; ESI-MS/MS, electro spray ionization tandem mass spectrometry; ISSD, infan
Keywords: CHX، cycloheximide; CHX, cycloheximide; DFO, deferoxamine; DMOG, dimethyloxalylglycine; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HIF-1α, hypoxia-inducible factor-1 alpha; ODD, oxygen degradatio
Keywords: CHX، cycloheximide; DSAP, disseminated superficial actinic porokeratosis; MVK, mevalonate kinase; CHX, cycloheximide; PK, porokeratosis; HIDS, hyperimmunoglobulinaemia D and periodic fever syndrome; MKD, mevalonate kinase deficiency; PP, porokeratosis ptychotropicaDSAP; MVK;
Keywords: CHX، cycloheximide; Carnosic acid; Glioma; Retinoblastoma; SOX2; Cyclin B1; ProteasomeCA, carnosic Acid; CDKs, cyclin dependent kinases; CHX, cycloheximide; DAPI, 4′,6-diamidino-2-phenylindole; DMSO, dimethyl sulfoxide; FBS, fetal bovine serum; GBM, glioblastoma; LCC, lactac
Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses
Keywords: CHX، cycloheximide; Lactimidomycin; Translation inhibitor; Antiviral; Dengue virus; Broad spectrum; Host-targeted antiviralDENV2, dengue virus 2; VSV, vesicular stomatitis virus; PV1, poliovirus 1; LTM, Lactimidomycin; CHX, Cycloheximide; MPA, mycophenolic acid; PFU, plaque-
Proteolytic cleavage in the S1–S2 linker of the Kv1.5 channel does not affect channel function
Keywords: CHX، cycloheximide; CHX, Cycloheximide; co-IP, Co-immunoprecipitation; hERG, Human ether-a-go-go-related gene; IKur, The ultra-rapidly activating delayed rectifier potassium current; PK, Proteinase KCell-surface protein; Electrophysiology; Kv1.5; Trafficking; Voltage-gated p
The involvement of cyclin D1 degradation through GSK3β-mediated threonine-286 phosphorylation-dependent nuclear export in anti-cancer activity of mulberry root bark extracts
Keywords: CHX، cycloheximide; Mulberry root bark; Anti-cancer; Cyclin D1 proteasomal degradation; Human colorectal cancerCDK, cyclin-dependent kinase; CHX, cycloheximide; ERK1/2, extracellular signal-regulated kinases1/2; GSK3β, glycogen synthase kinase 3 beta; IκK-α, IκB kinase-α; JN
Interference with Akt signaling pathway contributes curcumin-induced adipocyte insulin resistance
Keywords: CHX، cycloheximide; Curcumin; Protein kinase B; Autophagy; Ubiquitin proteasome system; AdipocytesAkt, Protein kinase B (PKB/Akt); BFA, Bafilomycin A1; CHX, Cycloheximide; CQ, Chloroquine; Cur, Curcumin; 2-DG, 2-deoxy-D-glucose; GFPu, A green fluorescence protein (GFP) modif
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling
Keywords: CHX، cycloheximide; ARE, antioxidant response element; Bach1, BTB and CNC homolog 1; bZip, basic region leucine zipper; ChIP, chromatin immunoprecipitation; CHX, cycloheximide; Crm1, chromosomal region maintenance 1; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride; FITC,
P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells
Keywords: CHX، cycloheximide; CHX, cycloheximide; ER, endoplasmic reticulum; hESC, human embryonic stem cell; hiPSC, human induced pluripotent stem cell; hPSC, human pluripotent stem cell; IMS, intermembrane space; MOMP, mitochondrial outer membrane permeabilization; PARP, poly(ADP-ri
Paraptosis in the anti-cancer arsenal of natural products
Keywords: CHX، cycloheximide; Paraptosis; Natural products; Cancer; Endoplasmic reticulum; Mitochondria; Vacuolation↑, upregulation; ↓, downregulation; 15d-PGJ2, 15-deoxy-Δ12,14-PGJ2; 2-APB, 2-aminoethoxydiphenyl borate; BKCa, Ca2+-activated K+ channel; CHX, cycloheximide; CuDIPS, Cu(
Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells
Keywords: CHX، cycloheximide; CHX, cycloheximide; LMB, leptomycin B; NLS, nuclear localisation signal; NP, nucleoprotein; TPCK, tosyl phenylalanyl chloromethyl ketone; vRNP, viral ribonucleoprotein; WT, wild-type; w/o, withoutInfluenza virus; Nuclear import; PB2
cAMP-activated Nr4a1 expression requires ERK activity and is modulated by MAPK phosphatase-1 in MA-10 Leydig cells
Keywords: CHX، cycloheximide; MAP kinase phosphatase; MKP-1; ERK1/2; Nr4a1; Nur77; Leydig cellsACTH, adrenocorticotropic hormone; cAMP, cyclic adenosine monophosphate; CHX, cycloheximide; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; LH, luteinizing hormone; MAPK, mitogen-activated
Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition
Keywords: CHX، cycloheximide; CDKs, cyclin-dependent kinases; CHX, cycloheximide; CK2, casein kinase II; CQ, chloroquine; CRBN, cereblon; RING, really interesting new gene; CRL4, cullin-4 RING E3 ligase; DDB1, damage-specific DNA-binding protein 1; ROC1, regulator of cullins-1; DRB, 5
Selenoprotein W controls epidermal growth factor receptor surface expression, activation and degradation via receptor ubiquitination
Keywords: CHX، cycloheximide; ANOVA, analysis of variance; CHX, cycloheximide; BS3, bis(sulfosuccinimidyl)suberate; SE, standard error of the mean; Sec, selenocysteineSelenium; Selenoprotein W; Epidermal growth factor receptor; Ubiquitination; Cancer
Vanderwaltozyma polyspora possesses two glycyl-tRNA synthetase genes: One constitutive and one inducible
Keywords: CHX، cycloheximide; aaRS, aminoacyl-tRNA synthetase; CHX, cycloheximide; DAPI, 4′,6-diamidino-2-phenylindole; GlyRS, glycyl-tRNA synthetase; cDNA, complementary DNA; 5-FOA, 5-fluoroorotic acid; GFP, green fluorescence protein; MTS, mitochondrial targeting signal; ORF, open r
Pculin02H, a curcumin derivative, inhibits proliferation and clinical drug resistance of HER2-overexpressing cancer cells
Keywords: CHX، cycloheximide; CHX, cycloheximide; EGFR, epithelial growth factor receptor; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NSCLC, non-small cell lung cancer; PBS, phosphate-buffered saline; PI, propidium iodideHER2; Pculin02H; G2/M arrest; Apoptosis
Transcription factor Nrf1 is negatively regulated by its O-GlcNAcylation status
Keywords: CHX، cycloheximide; AD1, acidic domain 1; ARE, antioxidant response element; bZIP, basic region-leucine zipper; CHX, cycloheximide; CNC, cap’n’collar; EGFP, enhanced green fluorescent protein; ER, endoplasmic reticulum; Glc, glucose; GCLM, glutamate cysteine ligase modifier
The Adhesion GPCR CD97/ADGRE5 inhibits apoptosis
Keywords: CHX، cycloheximide; Ab, antibody; AV, annexin V; CHX, cycloheximide; EGF, epidermal growth factor; GAIN, GPCR autoproteolysis-inducing; GPCR, G protein-coupled receptor; GPS, GPCR proteolysis site; mAb, monoclonal antibody; pAb, polyclonal antibody; PI, propidium iodide; SEM
Posttranscriptional regulation of T-type Ca2+ channel expression by interleukin-6 in prostate cancer cells
Keywords: CHX، cycloheximide; CHX, cycloheximide; FSK, forskolin; IL-6, interleukin-6; LNCaP, lymph node carcinoma of the prostate; NaBu, sodium butyrate; NED, neuroendocrine differentiationProstate cancer; Interleukin-6; Forskolin; T-type calcium channel; Neuroendocrine differentiati
TRC8 downregulation contributes to the development of non-alcoholic steatohepatitis by exacerbating hepatic endoplasmic reticulum stress
Keywords: CHX، cycloheximide; Adv, adenovirus; CHX, cycloheximide; Dgat1, DAG acyltransferase; ER, endoplasmic reticulum; FAS, fatty acid synthase; FBS, fetal bovine serum; GST, glutathione-s-transferase; HA, hemagglutinin; HFD, high-fat diet; KO, knockout; MCD, methionine and choline
KPC2 relocalizes HOXA2 to the cytoplasm and decreases its transcriptional activity
Keywords: CHX، cycloheximide; BiFC, bimolecular fluorescence complementation; CHX, cycloheximide; GST, glutathione S-transferase; HD, homeodomain; HOX, homeobox; ISH, in situ hybridization; KPC2, Kip1 ubiquitination-promoting complex 2; LMB, leptomycin B; ORF, open reading frame; r, r
Enhanced Ca2+ response and stimulation of prostaglandin release by the bradykinin B2 receptor in human retinal pigment epithelial cells primed with proinflammatory cytokines
Keywords: CHX، cycloheximide; [Ca2+]i, intracellular calcium ion concentration; BRB, blood–retinal barrier; CHX, cycloheximide; DAKD, lys-[des-Arg9]-BK; DALKD, lys-[Leu8][des-Arg9]-BK; GPCR, G-protein coupled receptor; hfRPE, human fetal retinal pigment epithelium; HI-FBS, heat-inacti
Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome
Keywords: CHX، cycloheximide; CHX, cycloheximide; EJC, exon junction complex; hERG, human ether-a-go-go-related gene; HPH, hygromycin B phosphotransferase; LQT2, long QT syndrome type 2; MO, morpholino oligonucleotide; NMD, nonsense-mediated mRNA decay; nt, nucleotide; PTC, premature
Induction of FKBP51 by aldosterone in intestinal epithelium
Keywords: CHX، cycloheximide; 11βHSD-2, type 2 11-beta-hydroxysteroid dehydrogenase; ANI, anisomycin; ANOVA, Analysis of Variance; CBX, carbenoxolone; CHX, cycloheximide; DAPI, diamidino-2-phenylindole; ENaC, epithelial Na+ channel; FKBP51, FK506 binding protein 51 kDa; GILZ, glucocor
Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic reticulum
Keywords: CHX، cycloheximide; BFA, brefeldin A; CHX, cycloheximide; DECP, diethylpyrocarbonate; ER, endoplasmic reticulum; IL, interleukin; PBMC, peripheral blood mononuclear cells; V-ATPase, vacuolar-type H(+)-ATPaseVacuolar-type H(+)-ATPase; Archazolid; Cytokines; Monocytes; Interle
Differential effects of caspase inhibitors on TNF-induced necroptosis
Keywords: CHX، cycloheximide; CHX, cycloheximide; PI, propidium iodide; PBS-T, PBS with 0.1% Tween 20Apoptosis; Necroptosis; Necrostatin-1; Z-VAD-fmk; Z-Asp-CH2-DCB; Z-DEVD-fmk
Cisplatin-induced cell death in Saccharomyces cerevisiae is programmed and rescued by proteasome inhibition
Keywords: CHX، cycloheximide; PCD, programmed cell death; ROS, reactive oxygen species; PI, propidium iodide; DHE, dihydroethidium; MG132, Carbobenzoxy-Leu-Leu-leucinal; c.f.u., colony forming units; cDDP, cisplatin; CHX, cycloheximide; DMSO, Dimethyl sulfoxide; HNSCC, head and neck s
Induction of autophagy by TOCP in differentiated human neuroblastoma cells lead to degradation of cytoskeletal components and inhibition of neurite outgrowth
Keywords: CHX، cycloheximide; 3-MA, 3-methyladenine; CHX, cycloheximide; DMEM, Dulbecco's modified Eagle's medium; ECL, enhanced chemiluminescence; NF-H, high molecular weight neurofilament; NF-L, low molecular weight neurofilament; OP, organophosphates; OPIDN, organophosphorous compo
Korean red ginseng extract induces proliferation to differentiation transition of human acute promyelocytic leukemia cells via MYC-SKP2-CDKN1B axis
Keywords: CHX، cycloheximide; AML, acute myeloid leukemia; APL, acute promyelocytic leukemia; ATO, arsenic trioxide; ATRA, all-trans retinoic acid; BSA, bovine serum albumin; CHX, cycloheximide; FBS, fetal bovine serum; KRGE, Korean red ginseng extract; NBT, nitro blue tetrazolium; PB
Identification of a PTC-containing DlRan transcript and its differential expression during somatic embryogenesis in Dimocarpus longan
Keywords: CHX، cycloheximide; 2,4-D, 2,4-dichlorophenoxyacetic acid; AS-NMD, alternative splicing coupled with NMD; CE, cotyledon-shaped embryos; CHX, cycloheximide; EC, embryogenic callus; GE, globular-shaped embryos; LEC, LEAFY COTYLEDON; NMD, nonsense-mediated mRNA decay; PTC, prem
Role of β-Catenin in regulating the balance between TNF-α- and Fas-induced acute liver injury
Keywords: CHX، cycloheximide; ALT, serum alanine aminotransferase; AST, aspartate aminotransferase; CHX, cycloheximide; GalN, d-galactosamine; GSH, serum glutathione; GSK3β, glycogen synthase kinase β; HCC, hepatocellular carcinoma; LPS, lipopolysaccharide; MDA, malondialdehyde; NO, N
Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs
Keywords: CHX، cycloheximide; Orlistat; Aspirin; Irinotecan; Liver; α/β fold hydrolases; Carboxylesterases; First passCES, carboxylesterase; CHX, cycloheximide; DMEM, Dulbecco's modified eagle medium; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PPD, pentyl carbamate of p-aminoben
Cycloheximide inhibits follicle-stimulating hormone β subunit transcription by blocking de novo synthesis of the labile activin type II receptor in gonadotrope cells
Keywords: CHX، cycloheximide; FSH, follicle-stimulating hormone; LH, luteinizing hormone; CHX, cycloheximide; GnRH, gonadotropin-releasing hormone; TGFβ, transforming growth factor β; ACVR2, Activin type II receptor; ALK, activin receptor-like kinase; FST-288, follistatin 288; CGA, ch
The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV
Keywords: CHX، cycloheximide; CHX, cycloheximide; CT, cryptotanshinone; DHT, dihydrotanshinone; DMEM, Dulbecco's modified Eagle's medium; γ-GCS, gamma-glutamate-cysteine ligase; H&E, hematoxylin and eosin; HMOX1, heme oxygenase-1; IHC, immunohistochemistry; MTT, 3-(4,5-dimethylthiazol
Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4
Keywords: CHX، cycloheximide; AA-861, 2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone; BQ, benzoquinone; CGD, chronic granulomatous disease; CHX, cycloheximide; DPI, diphenyliodonium; Duroquinone, 2,3,5,6-tetramethyl-1,4-benzoquinone; HQ, hydroquinone; tMetBQ, 2,5-dime
Activation of Akt through 5-HT2A receptor ameliorates serotonin-induced degradation of insulin receptor substrate-1 in adipocytes
Keywords: CHX، cycloheximide; T2DM, type 2 diabetes mellitus; 5-HT, 5-hydroxytryptamine (Serotonin); IRS-1, insulin receptor substrate-1; LDM, low density microsome; PI3 K, phosphatidylinositol-3 kinase; CHX, cycloheximide; Erk, extracellular-regulated kinase; mTOR, mammalian target o
Cycloheximide as a tool to investigate protein import in peroxisomes: A case study of the subcellular localization of isoprenoid biosynthetic enzymes
Keywords: CHX، cycloheximide; CHX, cycloheximide; CFP, cyan fluorescent protein; FPS, farnesyl diphosphate synthase; MVA, mevalonate; MVD, mevalonate 5-diphosphate decarboxylase; MVK, mevalonate kinase; PMK, 5-phosphomevalonate kinase; PTS, peroxisome targeting sequence; TDC, tryptoph
PMA induces GCMa phosphorylation and alters its stability via the PKC- and ERK-dependent pathway
Keywords: CHX، cycloheximide; CBP, cAMP response element-binding protein-binding protein; CHX, cycloheximide; DMSO, dimethyl sulfoxide; EGF, epidermal growth factor; ERK, extracellular signal-regulated kinase; GCMa, Drosophila glial cells missing mammalian homolog a; MEK, mitogen-acti
Interplay between two myogenesis-related proteins: TBP-interacting protein 120B and MyoD
Keywords: CHX، cycloheximide; TIP120B, TBP-interacting protein 120B; CHX, cycloheximide; DEX, dexamethasone; DM, differentiation medium; GM, growth medium; ChIP, chromatin immunoprecipitationTIP120B; CAND2; MyoD; Myogenesis; Transcriptional regulation
Nicotinamide treatment reduces the levels of histone H3K4 trimethylation in the promoter of the mper1 circadian clock gene and blocks the ability of dexamethasone to induce the acute response
Keywords: CHX، cycloheximide; dex, dexamethasone; NAM, nicotinamide; TSA, trichostatin A; CHX, cycloheximide; SIRT1, sirtuin (silent mating type information regulator 2 homolog 1); PARP-1, poly(ADP-ribose) polymerase 1; H3K4me3, histone H3 trimethylated at lysine residue 4; SAMe, S-ad
Regulation of Actinomycin D induced upregulation of Mdm2 in H1299 cells
Keywords: CHX، cycloheximide; ActD, Actinomycin D; CHX, cycloheximide; Dox, Doxorubicin; NEDD8, neural precursor cell expressed developmentally down-regulated 8; NEDP1, NEDD8-specific protease 1Mdm2; Actinomycin D; Ribosomal stress; NEDDylation
Regulation of cyclin T1 expression and function by an alternative splice variant that skips exon 7 and contains a premature termination codon
Keywords: CHX، cycloheximide; P-TEFb, positive transcription elongation factor b; PBMC, peripheral blood mononuclear cells; CHX, cycloheximide; WORT, wortmannin; HIV, human immunodeficiency virus; LTR, long terminal repeat; AMA, α-amanitin; PHA, phytohemagglutininCyclin T1 (CCNT1); Al
Light qualities and dose influence ascorbate pool size in detached oat leaves
Keywords: CHX، cycloheximide; AsA, ascorbate; APX, ascorbate peroxidase; BL, blue light; CAP, chloramphenicol; CHX, cycloheximide; DHA, dehydroascorbate; DHAR, dehydroascorbate reductase; GL, l-galactono-1,4-lactone; GLDH, l-galactono-1,4-lactone dehydrogenase; GR, glutathione reducta
Enhanced antitumor activity of vitamin C via p53 in Cancer cells
Keywords: CHX، cycloheximide; NAC, N-acetyl-l-cysteine; CHX, cycloheximide; DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; ELISA, enzyme-linked immunosorbent assay; IP, immunoprecipitation; ip, intraperitoneal; PBS