دانلود مقالات ISI درباره Cl-Ib-Meca + ترجمه فارسی

Anticancer activity study of A3 adenosine receptor agonists

Keywords: AC; adenylyl cyclase; A3AR; A3 Adenosine receptor; Caco-2; epithelial colorectal carcinoma; CHO; Chinese hamster ovary; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulphox

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

[1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists: Modifications at the 8 position to reach selectivity towards A3 adenosine receptor subtype

Keywords: G protein-coupled receptor; Adenosine receptor; A3 antagonist; [1,2,4]triazolo[1,5-c]pyrimidine; Molecular modeling; Docking; AR; adenosine receptor; cAMP; cyclic adenosine monophosphate; CCPA; 2-chloro-N6-cyclopentyladenosine; CHO; chinese hamster ovary;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A3 and A2A subtypes

Keywords: G protein-coupled receptors; Adenosine receptor antagonists; Imidazopyrazines; Bicyclic heteroaromatic systems; Ligand-receptor modeling studies; AR; adenosine receptor; AB-MECA; N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine; NECA; 5'-(N-ethyl-carboxa

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor

Keywords: G-protein-coupled receptors; Adenosine receptor antagonists; Pyrazolopyrimidines; Ligand-receptor modeling studies; AR; adenosine receptor; NECA; 5′-(N-ethyl-carboxamido)adenosine; cAMP; cyclic adenosine monophosphate; Cl-IB-MECA; 2-chloro-N6-(3-iodoben

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors

Keywords: AR; adenosine receptor; PD; Parkinson's disease; CCPA; 2-chloro-N(6)-cyclopentyladenosine; NECA; 5′-(N-ethyl-carboxamido)adenosine; cAMP; cyclic adenosine monophosphate; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)5′-(N-methylcarbamoyl)adenosine; DPCPX; 8

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2016 سفارش ترجمه

The stimulation of A3 adenosine receptors reduces bone-residing breast cancer in a rat preclinical model

Keywords: A3 adenosine receptors; Bone-residing breast cancer; Cl-IB-MECA; MRMT-1 cells; Rat tibia;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

A1 and A3 adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes

Keywords: ActD; actinomycin D; Ado; adenosine; ADA; adenosine deaminase; BAY 60-6583; 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; CHA; N(6)-cyclohexyladenosine; CGS 21680; 2-p-(2-carboxyethyl)phenethylamino-5′-N-ethylcarb

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Potentiation of cytotoxicity of paclitaxel in combination with Cl-IB-MECA in human C32 metastatic melanoma cells: A new possible therapeutic strategy for melanoma

Keywords: Paclitaxel; Cl-IB-MECA; MelanomaAc-DEVD-CHO, N-Ac-Asp-Glu-Val-Asp-CHO; AR, Adenosine receptor; Cl-IB-MECA, 2-chloro-N(6)-(3-iodobenzyl)-adenosine-5′-N-methyl-uronamide; DMSO, Dimethyl sulfoxide; DMEM-HG, Dulbecco's Modified Eagle's Medium–High Glucose; FB

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Cl-IB-MECA enhances TNF-α release in peritoneal macrophages stimulated with LPS

Keywords: TNF-α; Macrophages; LPS; Cl-IB-MECA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Functionally biased modulation of A3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

Keywords: CCPA; 2-chloro-N6-cyclopentyladenosine; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptor; LUF5833; 2-aminophenyl-6-(1H-imidazol-2-ylmethylsulfanyl)-pyridi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Adenosine A3 receptor-mediated cardioprotection against doxorubicin-induced mitochondrial damage

Keywords: A3 adenosine receptors; Ca2+ homeostasis; Cl-IB-MECA; Doxorubicin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process

Keywords: GPCRs; G protein-coupled receptors; AR; adenosine receptor; ADA; adenosine deaminase; cAMP; cyclic adenosine monophosphate; h; human; SAR; structure-affinity relationship; r; rat; DPCPX; 8-cyclopentyl-1,3-dipropyl-xanthine; CGS 21680; 2-[4-(2-carboxyeth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Human adenosine A3 receptor leads to intracellular Ca2+ mobilization but is insufficient to activate the signaling pathway via phosphoinositide 3-kinase γ in mice

Keywords: A3AR; adenosine A3 receptor; A3ARh/h mice; A3AR-humanized mice; BMMCs; bone marrow-derived mast cells; [Ca2+]i; intracellular Ca2+ concentration; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)adenosine-5′-N-methyluronamide; DT-A; diphtheria toxin A fragment; EP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه