دانلود مقالات ISI درباره CML، لوسمی مزمن میلوئیدی + ترجمه فارسی

کارآیی تطبیقی ​​تریسترومین کیناز مهار کننده در تنظیم خط سوم برای لوسمی میلوئیدی مزمن فاز مزمن پس از شکست مهارکننده های نسل دوم تیروزین کیناز

Comparative efficacy of tyrosine kinase inhibitor treatments in the third-line setting, for chronic-phase chronic myelogenous leukemia after failure of second-generation tyrosine kinase inhibitors

Keywords: CML، لوسمی مزمن میلوئیدی; 2G, second-generation; CML, chronic myelogenous leukemia; CP, chronic phase; CrI, credible interval; CCyR, complete cytogenetic response; MCyR, major cytogenetic response; R/I, resistant/intolerant; TKI, tyrosine kinase inhibitorCML; Ponatinib; Second-gen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

هدف قرار دادن متیلاسیون لیسین هیستون در سرطان

Targeting histone lysine methylation in cancer

Keywords: CML، لوسمی مزمن میلوئیدی; Methyltransferase; Demethylase; Chromatin; Epigenetic therapy; Histone methylation; Methyltransferase inhibitor2-OG, 2-Oxoglutarate; AML, Acute Myeloid Leukemia; CML, Chronic Myelogenous Leukemia; DNMT1, DNA Methyltransferase 1; DLBCL, Diffuse Large B-cel

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear

Keywords: CML، لوسمی مزمن میلوئیدی; CML, chronic myelogenous leukemia; FDA, Food and Drug Administration; CRP, collagen-related peptide; BTK, Bruton’s tyrosine kinase; PRP, platelet rich plasma; DIC, differential interference contrast; GPVI, glycoprotein VI; SFK, Src family kinase; GPCR, G

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Comparison of chest-CT findings of Influenza virus-associated pneumonia in immunocompetent vs. immunocompromised patients

Keywords: CML، لوسمی مزمن میلوئیدی; AML, acute myelogenous leukemia; MM, multiple myeloma; MDS, myelodysplastic syndrome; NHL, non-Hodgkin lymphoma; CLL, chronic lymphocytic leukemia; ALL, acute lymphocytic leukemia; PRCA, pure red cell aplasia; CML, chronic myelogenous leukemia; PCNSL, pri

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Adeno-associated virus mediated gene transfer of Shepherdin inhibits gallbladder carcinoma growth in vitro and in vivo

Keywords: CML، لوسمی مزمن میلوئیدی; AAV, Adeno-associated virus; AML, acute myeloid leukemia; AGE, agarose gel electrophoresis; CML, chronic myelogenous leukemia; DMSO, dimethyl sulfoxide; FITC, fluorescein isothiocyanate; GBC, gallbladder carcinoma; H&E, Hematoxylin–Eosin; Hsp90, heat shoc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Dynamics of ceramide generation and metabolism in response to fenretinide – Diversity within and among leukemia

Keywords: CML، لوسمی مزمن میلوئیدی; 4-HPR, N-(4-hydroxyphenyl)retinamide; ROS, reactive oxygen species; GC, glucosylceramide; SPT, serine palmitoyltransferase; SMase, sphingomyelinase; ALL, acute lymphoblastoid leukemia; AML, acute myelogenous leukemia; CML, chronic myelogenous leukemia; TL

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases

Keywords: CML، لوسمی مزمن میلوئیدی; ALL, acute lymphoblastic leukemia; AURKA, Aurora-A kinase; ADPKD, autosomal dominant polycystic kidney disease; CAS, Crk-associated substrate; CAS-L, Crk-associated substrate-lymphocyte; CML, chronic myelogenous leukemia; CRK, cellular receptor of kinase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors

Keywords: CML، لوسمی مزمن میلوئیدی; AL, activation loop; ALL, acute lymphoblastic leukemia; AS, activation segment; CDK, cyclin-dependent kinase; Chk, Csk homologous kinase; CML, chronic myelogenous leukemia; Csk, C-terminal Src kinase; C-spine, catalytic spine; EGFR, epidermal growth facto

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Clinical application of catalytically cleavable fluorescence probe technology for multiplexing quantification of BCR–ABL1 fusion transcripts

Keywords: CML، لوسمی مزمن میلوئیدی; CML, chronic myelogenous leukemia; Ph chromosome, Philadelphia chromosome; ALL, acute lymphoblastic leukemia; M-bcr, major breakpoint cluster region; IRIS, International Randomized Study of Interferon versus STI571; RQ-PCR, quantitative reverse transcript

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation

Keywords: CML، لوسمی مزمن میلوئیدی; Glycosyltransferases; N-glycosylation; Activity assay; Melanoma; MCAM; Transendothelial migrationAP, alkaline phosphatase; ATRA, all-trans-retinoic acid; CHO, Chinese hamster ovary; CML, chronic myelogenous leukemia; ESI-LTQ-FTICR, electrospray ionization

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Discrimination of malignant neutrophils of chronic myelogenous leukemia from normal neutrophils by support vector machine

Keywords: CML، لوسمی مزمن میلوئیدی; SVM, support vector machine; CML, chronic myelogenous leukemia; FCS, flow cytometry standard; PCR, polymerase chain reaction; ROC, receiver operating characteristic; BCR, breakpoint cluster region; ABL, Abelson murine leukemiaFlow cytometry; Immunophenoty

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Leukapheresis in management hyperleucocytosis induced complications in two pediatric patients with chronic myelogenous leukemia

Keywords: CML، لوسمی مزمن میلوئیدی; CML, chronic myelogenous leukemia; M, male; F, female; Hgb, hemoglobin; RBC, red blood cells; WBC, white blood cells; Plt, platelet; RT PCR, real-time polymerase chain reaction; LMWH, low molecular weight heparin; NSAID, nonsterod antiinflammatory drug; H

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Acquired resistance to drugs targeting receptor tyrosine kinases

Keywords: CML، لوسمی مزمن میلوئیدی; Akt, Ak (mouse strain) – thymoma; Axl, a receptor tyrosine kinase; Bcr-Abl, breakpoint cluster-Abelson tyrosine kinase; CML, chronic myelogenous Leukemia; CrkL, v-crk sarcoma virus CT10 oncogene homolog (avian)-like; DACH1, Dachshund homolog 1 (Drosophila

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells

Keywords: CML، لوسمی مزمن میلوئیدی; Berbamine derivatives (BBMDs); Jak2; Stat3; ApoptosisBBMDs, berbamine derivatives; STAT, signal transducer and activator of transcription; JAKs, Janus kinases; SFKs, Src family kinases; Tyk2, tyrosine kinase 2; CML, chronic myelogenous leukemia

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Bortezomib and sphingosine kinase inhibitor interact synergistically to induces apoptosis in BCR/ABl+ cells sensitive and resistant to STI571 through down-regulation Mcl-1

Keywords: CML، لوسمی مزمن میلوئیدی; SPK1, sphingosine kinase 1; S1P, sphingosine 1-phosphate; SKI, sphingosine kinase inhibitor; DMS, N,N-dimethylsphingosine; CML, chronic myelogenous leukemia; MEK, mitogenactivated protein kinase; ERK, extracellular signal regulating kinase; Mcl-1, myeloid

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Stem cell factor/c-kit signaling enhances invasion of pancreatic cancer cells via HIF-1α under normoxic condition

Keywords: CML، لوسمی مزمن میلوئیدی; SCF/c-kit; HIF-1α; Pancreatic cancer; Invasion; NormoxiaSCF, stem cell factor; CML, chronic myelogenous leukemia; GIST, gastrointestinal stromal tumor; SCLC, small cell lung cancer; HIF-1, hypoxia-inducible factor-1; HIF-1α, hypoxia-inducible factor-1α; H

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma

Keywords: CML، لوسمی مزمن میلوئیدی; CA, constitutively active; CML, chronic myelogenous leukemia; DMSO, dimethyl sulfoxide; DN, dominant negative; ERK, extracellular signal-regulated kinase; FITC, fluorescein isothiocyanate; GSH, glutathione; HCC, hepatocellular carcinoma; IκB, nuclear fact

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Normal stem cells and cancer stem cells: similar and different

Keywords: CML، لوسمی مزمن میلوئیدی; CSC, cancer stem cell; HF, hair follicle; HSC, hematopoietic stem cell; AML, acute myelogenous leukemia; CML, chronic myelogenous leukemia; Hh, HedgehogStem cell; Cancer stem cell; Cancer progression; Self-renewal; Plasticity; Interconversion; Cancer regr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Autophagy and tumorigenesis

Keywords: CML، لوسمی مزمن میلوئیدی; ARHI, aplasia Ras homolog member I; ATG, autophagy regulator; BafA, bafilomycin A1; Bif-1, Bax-binding protein-1; C-Vps, class C Vps complex; CML, chronic myelogenous leukemia; CQ, chloroquine; DRAM, damage-regulated autophagy modulator; ER, endoplasmic r

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Chemosensitization of human leukemia K562 cells to taxol by a Vanadium-salen complex

Keywords: CML، لوسمی مزمن میلوئیدی; CML, Chronic myelogenous leukemia; DMSO, Dimethyl sulfoxide; DTT, Dithiothreitol; EtBr/Ao, Ethidium bromide/Acridine orange; MTT, 3-(4,5 Dimethylthiazol-z-yl)-2,5-diphenyltetrazolium bromide; PBS, Phosphate buffer saline; PI, Propidium iodide; Pgp, P glyc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Personalized medicine: individualized care of cancer patients

Keywords: CML، لوسمی مزمن میلوئیدی; CLL, chronic lymphocytic leukemia; CML, chronic myelogenous leukemia; CR, complete remission; CT, cancer-testis; IHC, immunohistochemistry; MM, multiple myeloma; Rb, retinoblastoma protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Reciprocal regulation of Abl and receptor tyrosine kinases

Keywords: CML، لوسمی مزمن میلوئیدی; PDGF, platelet-derived-growth factor; PDGFR, platelet-derived-growth factor receptor; EGF, epidermal-growth factor; EGFR, epidermal-growth factor receptor; SH, Src-homology; CML, chronic myelogenous leukemia; IGF-1R, insulin-like growth factor receptor; A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of metabolites of meisoindigo in rat, pig and human liver microsomes by UFLC–MS/MS

Keywords: CML، لوسمی مزمن میلوئیدی; CML, chronic myelogenous leukemia; UFLC, ultra fast liquid chromatography; MS, mass spectrometry; MS/MS, tandem mass spectrometry; QTRAP, hybrid triple quadrupole linear ion trap; MRM, multiple reaction monitoring; EPI, Enhanced Product IonIn vitro metabo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Converting cell lines representing hematological malignancies from glucocorticoid-resistant to glucocorticoid-sensitive: Signaling pathway interactions

Keywords: CML، لوسمی مزمن میلوئیدی; ALL, acute lymphoblastic leukemia; AML, acute myelogenous leukemia; CML, chronic myelogenous leukemia; Dex, dexamethasone; FBS, fetal bovine serum; Fsk, forskolin; GR, glucocorticoid receptor; IDV, individual densitometric values; ip, cell permeable; JNK,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

STI571 sensitizes breast cancer cells to 5-fluorouracil, cisplatin and camptothecin in a cell type-specific manner

Keywords: CML، لوسمی مزمن میلوئیدی; 5-FU, 5-fluorouracil; CML, chronic myelogenous leukemia; ER, estrogen receptor; PR, progesterone receptor; (−), negative; (+), positive; topo I, topoisomerase I; PARP, poly(ADP-ribose) polymerase; TCA, trichloroacetic acid; CI, combination index; MMS, met

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Xanthogranulomas associated with hematologic malignancy in adulthood

Keywords: CML، لوسمی مزمن میلوئیدی; B-ALL, B-cell acute lymphoblastic lymphoma; CML, chronic myelogenous leukemia; XG, xanthogranulomatosis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Risk of Leukemia Among Survivors of Testicular Cancer: A Population-based Study of 42,722 Patients

Keywords: CML، لوسمی مزمن میلوئیدی; Testicular Neoplasms; Leukemia; Second Primary Neoplasms; Cohort StudiesEAR, excess absolute risk; ERR, excess relative risk; AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; CML, chronic myelogenous leukemia; SEER, Surveillance, Epidemiolo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Involvement of ERK/MAPK pathway in megakaryocytic differentiation of K562 cells induced by 3-hydrogenkwadaphnin

Keywords: CML، لوسمی مزمن میلوئیدی; BSA, bovine serum albumin; Cdk, cyclin-dependent kinase; CDKI, cyclin-dependent kinase inhibitor; CML, chronic myelogenous leukemia; ERK, extracellular signal-regulated kinase; FBS, fetal bovine serum; GPA, glycophorine A; 3-HK, 3-hydrogenkowadaphnin; JNK

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Dermatomyositis induced by drug therapy: A review of case reports

Keywords: CML، لوسمی مزمن میلوئیدی; ANA, antinuclear antibody; CML, chronic myelogenous leukemia; DM, dermatomyositis; PM, polymyositis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Tyrosine Phosphorylation in the SH3 Domain Disrupts Negative Regulatory Interactions within the c-Abl Kinase Core

Keywords: CML، لوسمی مزمن میلوئیدی; CML, chronic myelogenous leukemia; NCap, N-terminal cap; HX, hydrogen-deuterium exchange; MS, mass spectrometry; GST, glutathione S-transferasehydrogen exchange; mass spectrometry; phosphorylation; Src-family kinase; Bcr-Abl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Involvement of a Rho-ROCK-JNK pathway in arsenic trioxide-induced apoptosis in chronic myelogenous leukemia cells

Keywords: CML، لوسمی مزمن میلوئیدی; APL, acute promyelocytic leukemia; CML, chronic myelogenous leukemia; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; DN MKK, dominant negative MAPK kinase; MLC, myosin light chain; GEF, guanine nucleotide exchange factorArsenic tr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of IRF-8 and IRF-1 target genes in activated macrophages

Keywords: CML، لوسمی مزمن میلوئیدی; CML, chronic myelogenous leukemia; CXCL16, Cxc chemokine ligand 16; ICSBP, interferon consensus sequence binding protein; IFN, interferon; IL-17R, interleukin-17 receptor; IRF, IFN regulatory factor; KO, knockout; LIF, leukemia inhibitory factor; MAP4K4,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Redirecting T lymphocyte specificity by T cell receptor gene transfer – A new era for immunotherapy

Keywords: CML، لوسمی مزمن میلوئیدی; T lymphocytes; Immunotherapy; Gene transfer; Retroviral vectorCAR, chimeric antibody receptor; CML, chronic myelogenous leukemia; CMV, cytomegalovirus; CTL, cytolytic T lymphocyte; DC, dendritic cell; EBV, Epstein-Barr virus; GALV, gibbon ape leukemia vir

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2007 سفارش ترجمه

Spontaneous thoracic air-leakage syndrome in patients following allogeneic hematopoietic stem cell transplantation: Causes, CT-follow up and patient outcome

Keywords: CML، لوسمی مزمن میلوئیدی; GvHDg, raft versus host disease; MDS, myelodysplastic syndrome; m, male; f, female; CML, chronic myelogenous leukemia; TBI, total body irradiation; sPM, spontaneous pneumomediastinum; PP, pneumopericardium; IE, interstitial emphysema; sPT, spontaneous pne

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular regulation of receptor tyrosine kinases in hematopoietic malignancies

Keywords: CML، لوسمی مزمن میلوئیدی; RTK, receptor tyrosine kinase; AML, acute myeloid leukemia; CML, chronic myelogenous leukemia; EGF, epidermal growth factor; VEGF, vascular endothelial growth factor; HGF, hepatocyte growth factor; MSP, macrophage stimulating protein; FGF, fibroblast grow

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Stochastic modeling of drug resistance in cancer

Keywords: CML، لوسمی مزمن میلوئیدی; CML, Chronic myelogenous leukemia; ODE, Ordinary differential equation; PDE, Partial differential equationMulti-drug therapy; Mathematical model; Targeted drugs; Pre-existence; Treatment success

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه