
Development of Pegylated Liposomal Vincristine Using Novel Sulfobutyl Ether Cyclodextrin Gradient: Is Improved Drug Retention Sufficient to Surpass DSPE-PEG-Induced Drug Leakage?
Keywords: پیچیدگی; liposomes; vincristine; sulfobutyl ether cyclodextrin; drug targeting; complexation; toxicity; pharmacokinetics; circulation time; drug loading; efficacy;