Keywords: سیگنال COP9; Hb-Y-X; hydrophobic-tyrosine-X motif; PA; proteasome activator; CSN; COP9 signalosome; CRL; Cullin RING E3 ligase; PAN; proteasome-activating nucleotidase; Ribophagy; Ribosome autophagy; UbD; ubiquitin-binding domain; DUb; deubiquitinationg enzyme; UPS; u
مقالات ISI سیگنال COP9 (ترجمه نشده)
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Keywords: سیگنال COP9; Mass spectrometry/methods; Chromatography/methods; Protein complexes; Post-translational modifications; Protein isoforms; COP9 signalosome;
Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3
Keywords: سیگنال COP9; COPS3; The third subunit of the COP9 signalosome; ccRCC; clear cell renal cell carcinoma; qRT-PCR; quantitative real-time PCR; CCK-8; Cell Counting Kit-8; CSN; COP9 signalosome; COP; constitutive photomorphogenesis; siRNA; small interfering RNA; FBS; Feta
Integrating plant and animal biology for the search of novel DNA damage biomarkers
Keywords: سیگنال COP9; ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING
CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligase during adipogenesis
Keywords: سیگنال COP9; COP9 signalosome; CAND1; Cullin 3; Keap1; Adipogenesis;
Diversity of COP9 signalosome structures and functional consequences
Keywords: سیگنال COP9; COP9 signalosome; 3D structure; Deneddylation; CSN5; CSN subunit isoform;
CSN-associated USP48 confers stability to nuclear NF-κB/RelA by trimming K48-linked Ub-chains
Keywords: سیگنال COP9; NF-κB; COP9 signalosome; RelA; Deubiquitinase; CK2; Nuclear protein turnover;
Crystal structure of the human CSN6 MPN domain
Keywords: سیگنال COP9; COP9 signalosome; CSN6; MPN domain; JAMM motif; Isopeptidase activity; Deneddylation
Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes
Keywords: سیگنال COP9; COP9 signalosome; Lid; Deneddylation; Cryo-electron microscopy; 3D-reconstruction; Single-particle analysis;
Plant COP9 Signalosome subunit 5, CSN5
Keywords: سیگنال COP9; COP9 signalosome; CSN5/Jab1; CSN6; Gene duplication; Differential expression; Gene homology;
Ubiquitin at work: The ubiquitous regulation of the damage recognition step of NER
Keywords: سیگنال COP9; NER; Nucleotide excision repair; UV; Ultraviolet light; CPDs; Cyclobutane pyrimidine dimers; 6-4PPs; 6-4 photoproducts; PTMs; Post-translational modifications; UPS; Ubiquitin-proteasome system; DUB; Deubiquitylating enzyme; DCAFs; DDB1- and CUL4-associa
The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells
Keywords: سیگنال COP9; AP-1; activator protein-1; APC; adenomatous polyposis coli; CK1; casein kinase 1; CoIP; co-immunoprecipitation; CRC; colorectal cancer; CRL; cullin RING E3 ubiquitin ligase; CSN; COP9 signalosome; CSN5; fifth subunit of the CSN; Cul1; cullin-1; GSK-3β; g
CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesis
Keywords: سیگنال COP9; COP9 signalosome; F-box proteins; Preadipocytes; p27; Skp2;
Deregulation of the COP9 signalosome–cullin-RING ubiquitin-ligase pathway: Mechanisms and roles in urological cancers
Keywords: سیگنال COP9; COP9 signalosome; Cullin-RING ubiquitin ligases; Skp2; Urological cancer; microRNAs; Tumor therapyβ-TrCP, β-transducin repeat-containing protein; CAND1, cullin-associated NEDD8-dissociated protein 1; CSN, COP9 signalosome; CRL, cullin-RING ubiquitin ligas
Depletion of CSN5 inhibits Ras-mediated tumorigenesis by inducing premature senescence in p53-null cells
Keywords: سیگنال COP9; CSN5; COP9 signalosome; Ras; p53; Tumorigenesis; Senescence; Cell cycle;
Role of CSN5/JAB1 in Wnt/β-catenin activation in colorectal cancer cells
Keywords: سیگنال COP9; CSN5; COP9 signalosome; Protein degradation; Cullin-RING-ubiquitin ligase; MIF; p53; APC; adenomatous polyposis coli; CDK; cyclin-dependent kinase; CHX; cycloheximide; COP; constitutive photomorphogenesis; CSN; COP9 signalosome; CRC; colorectal cancer; CR
The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6
Keywords: سیگنال COP9; MPN domain; JAMM motif; COP9 signalosome; CSN6; Crystal structure;
Many jobs for one good cop - The COP9 signalosome guards development and defense
Keywords: سیگنال COP9; CSN; COP9 signalosome; CRL; CULLIN-RING E3 ubiquitin ligase; FBP; F-box protein; E3; E3 ubiquitin ligase; JA; jasmonic acid; SA; salicylic acid; COP9 signalosome; CULLIN-RING E3 ubiquitin ligase; F-Box protein; Ubiquitin proteasome system; Plant developme
COP9 signalosome function in the DDR
Keywords: سیگنال COP9; COP9 signalosome; Nedd8; Cullin-RING ubiquitin ligase; Nucleotide excision repair; Checkpoint control;
DELLA proteins restrain germination and elongation growth in Arabidopsis thaliana COP9 signalosome mutants
Keywords: سیگنال COP9; Arabidopsis; COP9 signalosome; DELLA protein; E3 ubiquitin ligase; Gibberellic acid; Protein degradation; Signal transduction
The COP9 signalosome and its role in plant development
Keywords: سیگنال COP9; Arabidopsis; Auxin response; Cell cycle; COP9 signalosome; CSN5; DNA damage; E3 ubiquitin ligases; NEDD8; Ubiquitin
CSN5/Jab1 controls multiple events in the mammalian cell cycle
Keywords: سیگنال COP9; Cell cycle; CSN5/Jab1; Neddylation; Cell proliferation; COP9 signalosome; Senescence; Endocycle
The COP9 signalosome controls ubiquitinylation of ABCA1
Keywords: سیگنال COP9; ABCA1; COP9 signalosome; Ubiquitin; Macrophage; CSN; Cholesterol
The COP9 signalosome negatively regulates proteasome proteolytic function and is essential to transcription
Keywords: سیگنال COP9; COP9 signalosome; Cullin; Nedd8; Proteasome; Transcription;
CSN5 binds to misfolded CFTR and promotes its degradation
Keywords: سیگنال COP9; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; CSN; COP9 signalosome; ERAD; ER-associated degradation; ERQC; ER-quality control; CFTR; CSN5; COP9 signalosome; Interaction and degradation;
CAND1 enhances deneddylation of CUL1 by COP9 signalosome
Keywords: سیگنال COP9; CAND1; COP9 signalosome; Deneddylation; Ubiquitin; CUL1; SCF E3 ubiquitin ligase; Cullin-RING ligase; Cullin; Nedd8; Ubiquitination;
The Arabidopsis inositol 1,3,4-trisphosphate 5/6 kinase, AtItpk-1, is involved in plant photomorphogenesis under red light conditions, possibly via interaction with COP9 signalosome
Keywords: سیگنال COP9; Arabidopsis; COP9 signalosome; Inositol 1,3,4-trisphosphate 5/6 kinase; Protein kinase; Red light; AtItpk-1; Arabidopsis inositol 1,3,4-trisphosphate 5/6 kinase; CaMV; Cauliflower mosaic virus; co-IP; co-immunoprecipitation; CSN; the COP9 signalosome; 5/6
Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation
Keywords: سیگنال COP9; COP9 signalosome; Cell cycle; Jab1; ras transformation; Cdk inhibitor p27; Anchorage dependence;
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif
Keywords: سیگنال COP9; C60SMIF; MIF mutant with Cys60 exchanged for Ser; CALC; Cys-Ala-Leu-Cys motif; CSN; COP9 signalosome; CSN5; subunit 5 of COP9 signalosome; IVT; in vitro transcription/translation; FCS; fetal calf serum; JAB1; c-Jun activation domain binding protein-
COPing with hypoxia
Keywords: سیگنال COP9; COP9 signalosome; CSN; Hypoxia; VHL; CSN5; Jab1;