CXCR4 signaling mediates morphine-induced tactile hyperalgesia
Keywords: CXCR4; CXCL12; SDF1; Chemokine; Opioid-induced hyperalgesia;
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Expression of CXCR7 chemokine receptor in human meningioma cells and in intratumoral microvasculature
Keywords: Meningioma; CXCL11; CXCL12; CXCR4; CXCR7;
The functional role of reactive stroma in benign prostatic hyperplasia
Keywords: Reactive stroma; BPH; Tenascin-C; IL-8; CXCL12; Hyperplasia
Heat-killed Enterococcus faecalis Alters Nitric Oxide and CXCL12 Production but not CXCL8 and CCL3 Production by Cultured Human Dental Pulp Fibroblasts
Keywords: CCL3; chemokines; CXCL8; CXCL12; dental pulp fibroblasts; Enterococcus faecalis; innate immunity; nitric oxide; pulpitis
Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells
Keywords: CXCL12; Tamoxifen; Breast cancer
CXCL12 alone is insufficient for gliomagenesis in Nf1 mutant mice
Keywords: CXCL12; NF1; Glioma; cAMP; AMD3100
Disruption of neuronal CXCR4 function by opioids: Preliminary evidence of Ferritin Heavy Chain as a potential etiological agent in neuroAIDS
Keywords: CXCR4; CXCL12; Opiates; Ferritin heavy chain; neuroAIDS; NR2B
Tumor-stroma co-evolution in prostate cancer progression and metastasis
Keywords: AR; androgen receptor; ARCaP; androgen refractory prostate cancer; β2M; β2-microglobulin; BDNF; brain derived neurotropic factor; BMP; bone morphogenetic protein; BSP; bone sialoprotein; CAF; cancer-associated fibroblast; CCL5; chemokine (C-C) ligand
Insights into the regulation of chemokine receptors by molecular signaling pathways: Functional roles in neuropathic pain
Keywords: Neuropathic pain; Chemokine; CXCL12; CCL2; Transcription factor; NFAT;
The chemokine receptor CXCR7 is expressed on lymphatic endothelial cells during renal allograft rejection
Keywords: chemokines; CXCL12; CXCR7; lymphatic endothelial cell; renal allograft
Differential regulation of CXCL12 and PACAP mRNA expression after focal and global ischemia
Keywords: CXCL12; PACAP; CXCR4; SDF-1; Neurogenesis; Inflammation; Neuroprotection; Stroke; Hippocampus; Stem cell; Ischemia
SDF1/CXCL12 (−801GA) polymorphism is a prognostic factor after treatment initiation in Waldenstrom macroglobulinemia
Keywords: Waldenstrom macroglobulinemia; SDF1; CXCL12; Polymorphism; CXCR4
The roles of chemokine CXCL12 in embryonic and brain tumor angiogenesis
Keywords: Brain tumor; Angiogenesis; Vasculogenesis; CXCL12; CXCR4; CXCR7
Lipopolysaccharides increase the amount of CXCR4, and modulate the morphology and invasive activity of oral cancer cells in a CXCL12-dependent manner
Keywords: Oral cancer; Invasion; LPS; CXCR4; CXCL12; Filopodia; Cdc42
PI3Kγ activation by CXCL12 regulates tumor cell adhesion and invasion
Keywords: CXCR4; CXCL12; Chemokines; Chemokine receptors; Adhesion; Invasion; PI3Kγ; G proteins
Chemokine signaling in cancer: One hump or two?
Keywords: Chemokine; CXCR4; CXCL12; Cancer; Desensitization
SDF-1 stimulates neurite growth on inhibitory CNS myelin
Keywords: BDA; biotinylated dextrane amine; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; CST; corticospinal tract; CXCL12; CXC chemokine ligand 12; CXCR4; CXC chemokine receptor 4; CXCR7; CXC chemokine receptor 7; DRG neurons; dorsal root gang
CXCL12/SDF-1 over-expression in human insulinomas and its biological relevance
Keywords: Insulinoma; Islet of Langerhans; CXCL12
CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis
Keywords: CXCL12; CXCR4; CXCR7; neutrophils; monocytes; ocular inflammation; T cells; uveitis
Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors
Keywords: Chemokine; Chemokine receptor; CXCR4; CXCL12; SDF-1;
Regulation of CXCL12 and CXCR4 expression by human brain endothelial cells and their role in CD4+ and CD8+ T cell adhesion and transendothelial migration
Keywords: Blood–brain barrier; Cytokines; T cell trafficking; CXCL12; CXCR4; Neuroinflammation
Relationships between glycosaminoglycan and receptor binding sites in chemokines—the CXCL12 example
Keywords: Glycosaminoglycans; Heparan sulfate; Chemokines; Receptors; CXCL12; Interactions; Structure
Dock2 participates in bone marrow lympho-hematopoiesis
Keywords: Hematopoietic stem/progenitor cells; Dock2; CXCR4; CXCL12
Chemokine receptor expression on infiltrating lymphocytes from abdominal aortic aneurysms: Role of CXCR4–CXCL12 in lymphoid recruitment
Keywords: Abdominal aortic aneurysm; Human; Lymphocyte; CXCL12; Chemokines
CXCL12/CXCR4 signaling promotes human thymic dendritic cell survival regulating the Bcl-2/Bax ratio
Keywords: Human thymus; Thymic dendritic cells; CXCL12; Survival
Intracellular mediators of CXCR4-dependent signaling in T cells
Keywords: CXCL12; T cell chemotaxis; CXCR4; Gi protein
Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
Keywords: Exercise; Tg2576; Alzheimer disease; CXCL1; CXCL12; Cognition; Running; AD model; Inflammation; Neuroinflammation
HIV-1-Tat potentiates CXCL12/Stromal Cell-Derived Factor 1-induced downregulation of membrane CXCR4 in T lymphocytes through Protein kinase C zeta
Keywords: T lymphocytes; HIV-1 tat; CXCR4; CXCL12; Protein kinase zeta; Receptor internalization;
CXCR4 and CXCL12 down-regulation: A novel mechanism for the chemoprotection of 3,3′-diindolylmethane for breast and ovarian cancers
Keywords: 3,3′-Diindolylmethane; DIM; CXCR4; CXCL12; Cancer metastasis
Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis
Keywords: Pulmonary fibrosis; Fibrocytes; Fibroblasts; CXCL12; Fibroblastic foci
Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues
Keywords: Asthma; microarrays expression profiling; candidate genes; genetic association study; tagging single nucleotide polymorphism; 15-lipoxygenase; AHR; Airway hyperresponsiveness; ALOX15; Arachidonate 15-lipoxygenase gene; CAPPS; Canadian Asthma Primary Preve
CXCR4 engagement promotes dendritic cell survival and maturation
Keywords: Langerhans cell; Dendritic cell; Maturation; Survival; Antagonist; CXCR4; CXCL12; Proliferation
RNA interference-mediated knockdown of DNMT1 and DNMT3B induces CXCL12 expression in MCF-7 breast cancer and AsPC1 pancreatic carcinoma cell lines
Keywords: DNA methyltransferases; CXCL12; Breast and pancreatic cancers
Characterization of cDNA and genomic sequences encoding a canine chemokine receptor, CXCR4 and its ligand CXCL12
Keywords: cDNA cloning; CXCR4; CXCL12; Dog
H4 histamine receptor mediates optimal migration of mast cell precursors to CXCL12
Keywords: Mast cell precursors; CXCL12; histamine; H4 receptor; cell migrationAPC, Allophycocyanin; FITC, Fluorescein isothiocyanate; FSC, Forward side scatter; LTB4, Leukotriene B4; MC, Mast cell; PC5, Peridinin chlorophyll protein-cyanin 5.5; PE, Phycoerythrin; P
Epigenetic up-regulation of CXCR4 and CXCL12 expression by 17 β-estradiol and tamoxifen is associated with formation of DNA methyltransferase 3B4 splice variant in Ishikawa endometrial adenocarcinoma cells
Keywords: CXCL12; CXCR4; Tamoxifen; 17 β-estradiol; DNA methyltransferases;
Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
Keywords: Chemokine; CXCL12; AMD3100; Tg2576; Learning; Inflammation; Cognition; Brain; AD; GeneChip
15-Deoxy-Î12,14-prostaglandin J2 down-regulates CXCR4 on carcinoma cells through PPARγ- and NFκB-mediated pathways
Keywords: CAY10410; 9,10-dihydro-15-deoxy-Î12,14-prostaglandin J2; COX; cyclooxygenase; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; GW9662; 2-chloro-5-nitro-N-phenylbenzamide; IKK; inhibitor of κB kinase; MAPK; mitogen-activated protein ki
CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells
Keywords: Renal cell carcinoma; CXCL12; CXCR4; Integrins; Adhesion; Chemotaxis
Phosphodiesterase 8 (PDE8) regulates chemotaxis of activated lymphocytes
Keywords: Lymphocyte chemotaxis; Cyclic nucleotide phosphodiesterase; CXCL12; cAMP signaling; PDE8; Dipyridamole
Stromal cell-derived factor 1 (CXCL12) binds to endothelial cells and signals through a receptor different from CXCR4
Keywords: Chemokine binding; Angiogenesis; CXCL12; Endothelial cell; Receptor; Antagonist; Signal transduction
CXCR4 modulates contractility in adult cardiac myocytes
Keywords: Calcium; Chemokines; Chemokine receptors; Contractility; CXCL12; CXCR4; SDF
Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing
Keywords: SDF-1; CXCL12; Chemokine; Homing; Stem cell
A role for CXCL12 (SDF-1α) in the pathogenesis of multiple sclerosis: Regulation of CXCL12 expression in astrocytes by soluble myelin basic protein
Keywords: CXCL12; Multiple sclerosis; Chemokines; MBP; Signaling
Stromal cell-derived factor-1 (SDF-1) expression in embryonic mouse cerebral cortex starts in the intermediate zone close to the pallial-subpallial boundary and extends progressively towards the cortical hem
Keywords: Chemokine; Cytokine; SDF-1; CXCL12; CXCR4; Embryo; Development; Interneuron; Intermediate zone; Migration; PSA-NCAM; Neocortex; Cerebral cortex; Cortical plate; Hippocampus; Cortical hem; Pallium; Subpallium; Basal ganglia;
Protein-tyrosine kinase, Syk, is required for CXCL12-induced polarization of B cells
Keywords: Protein-tyrosine kinase; Syk; CXCL12; CXCR4; Polarization; Migration; Adhesion; Integrin; Hematopoiesis;
CCR2-64I and CXCL12 3â²A alleles confer a favorable prognosis to AIDS patients undergoing HAART therapy
Keywords: Antiretroviral therapy; Chemokines; HIV-1; CCR5; CXCL12; CCR2;
Constitutive expression of three novel catfish CXC chemokines: homeostatic chemokines in teleost fish
Keywords: CXCL2; CXCL12; CXCL14; Chemokine; Fish; Cytokine; Infection; Gene expression; Catfish; Inflammation; Homeostatic;
Two different pathways link G-protein-coupled receptors with tyrosine kinases for the modulation of growth and survival in human hematopoietic progenitor cells
Keywords: AG 82; AG 490, tyrphostin tyrosine kinase inhibitors; BFU-E; burst forming unit-erythroid; CXCR4; CXC-chemokine receptor 4, specifically recognizing CXCL12; Epo; erythropoietin; Flt-3L; ligand of flt-3 receptor; G-CSF; granulocyte colony-stimulating facto