Keywords: CI; confidence interval; CYP11A1; cytochrome P450 family 11 subfamily A member 1; CYP17A1; cytochrome P450 family 17 subfamily A member 1; CYP19A1; cytochrome P450 family 19 subfamily A member 1; DDD; dichlorodiphenyldichloroethane; DDE; dichlorodiphenyld
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: TH; Thyroid hormone; THs; Thyroid hormones; T3; 3,5,3â²-l-triiodothyronine; HPT; Hypothalamic-pituitary-thyroid axis; HPG; Hypothalamic-pituitary-gonadal axis; CRH; Corticotropin-releasing hormone; CRF; corticotropin-releasing factor; GnIH; Gonadotropin
Keywords: Androgen receptor; CYP17A1; Disorders of sex development; Exome sequencing; SRD5A2; DSD; disorders of sex development; NGS; next-generation sequencing; VUS; variants of uncertain clinical significance;
Keywords: 11KT; 11-ketotestosterone; 17bhsd; 17β-hydroxysteroid dehydrogenase; 17P; 17α-hydroxyprogesterone; 17,20bP; 17,20β-dihydroxy-4-pregnen-3-one; 20b-HSD; 20β-hydroxysteroid dehydrogenase; 20βS; 17,20β,21-trihydroxy-4-pregnen-3-one; actRIIB; activin rec
Keywords: Mice; Leydig cells; HSD3B; Cell morphology; Hsd3b6; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6; Cyp17a1; cytochrome P450, family 17, subfamily a, polypeptide 1; Star; steroidogenic acute regulatory protein; Cyp11a1; cytoc
Keywords: Prostate; Cancer; CYP17A1; Inhibitor; Lyase; Hydroxylase;
Keywords: Epidemiology; Single Nucleotide Polymorphisms; Colon Cancer; eQTL; CRC; colorectal cancer; CYP17A1; cytochrome P450, family 17, subfamily A, polypeptide 1; EIF3H; eukaryotic translation initiation factor 3, subunit H; eQTL; expression quantitative trait l
Keywords: SNP; SRD5A1; SRD5A2; CYP17A1; Prostate cancer; OpenArray;
Keywords: Disorder of sexual development; Lipoid congenital adrenal hyperplasia; CYP11A1; HSD3B2; CYP17A1; HSD17B3; SRD5A2; POR and CYB5 deficiencies; AKR1C2/4 genesTroubles du développement sexuel; Hyperplasie congénitale lipoide des surrénales; Déficits en CYP11A
Keywords: 3β-HSD; 3β-hydroxysteroid dehydrogenase; 17β-HSD; 17β-hydroxysteroid dehydrogenase; BMP4; bone morphogenic protein 4; BW; body weight; ChIP; chromatin immunoprecipitation; CYP11A1; cytochrome P450 cholesterol side-chain cleavage enzyme; CYP17A1; cytoc
Keywords: CYP17A1; Steroidogenesis; Sulfonated steroids; Pregnenolone sulfate; Mass spectrometry;
Keywords: qPCR; quantitative RT-PCR; 3β-HSD1; 3β-hydroxysteroid dehydrogenase type 1; 3β-HSD2; 3β-hydroxysteroid dehydrogenase type 2; CYP11A1; cholesterol side-chain cleavage enzymes; CYP17A1; cytochrome P45017A1; 17β-HSD5; 17β-hydroxysteroid dehydrogenase t
Keywords: SCs; ovarian cortical stromal cells; SMs; ovarian medullary stromal cells; TCs; theca cells; GCs; granulosa cells; STAR; steroidogenic acute regulatory protein; CYP11A1; Cholesterol side-chain cleavage cytochrome P450; CYP17A1; 17alpha-hydroxylase/C17, 20
Paeoniflorin extract reverses dexamethasone-induced testosterone over-secretion through downregulation of cytochrome P450 17A1 expression in primary murine theca cells
Keywords: CYP11A1; cytochrome P450 side chain cleavage; CYP17A1; cytochrome P450 17A1; P; progesterone; PCOS; polycystic ovarian syndrome; PFE; paeoniflorin extract; T; testosterone; Polycystic ovarian syndrome; Theca cell; Testosterone; Chinese herbal medicine; Pa
Efficiency of the sulfate pathway in comparison to the Î4- and Î5-pathway of steroidogenesis in the porcine testis
Keywords: A4; androstenedione; Aβ; andien β-synthase activity of CYP17A1; ACN; acetonitrile; ANβ; androsta-5,16-dien-3β-ol; b5; cytochrome b5; CPR; cytochrome P450 oxidoreductase; CYB5A; CYB5âB isoforms of cytochrome b5; CYB5R; cytochrome b5 reductase; DHEA;
Identification of a novel mutation (Ala66Thr) of SRY gene causes XY pure gonadal dysgenesis by affecting DNA binding activity and nuclear import
Keywords: AR; androgen receptor; CYP11A1; cytochrome P450 family 11 subfamily a member 1; CYP17A1; cytochrome P450 family 17 subfamily a member 1; DHH; desert hedgehog; DMRT1/2/3; doublesex and mab-3 related transcription factor 1/2/3; DSD; disorders of sex develop
Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis
Keywords: Actb/ACTB; gene/protein for β-actin; AKT; protein for protein kinase B (AKT/PRKGB); BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cyp11a1; gene for cytochrome P450 side chain cleavage enzyme; Cyp17
Pig StAR: mRNA expression and alternative splicing in testis and Leydig cells, and association analyses with testicular morphology traits
Keywords: Pig; Steroidogenic acute regulatory protein (StAR); Alternative splicing; Genetic variants; Reproductive traits; LCs; Leydig cells; SSCs; spermatogonial stem cells; CYP11A1; cytochrome P450 family 11 subfamily A member 1; HSD3B; 3β-hydroxysteroid dehydro
A PK/PD study of Delta-4 abiraterone metabolite in metastatic castration-resistant prostate cancer patients
Keywords: 3β-HSD1; 3β-hydroxysteroid dehydrogenase/Î5â4 isomerase 1; CYP17A1; 17αâhydroxylase/17,20âlyase; Î4A; Î4-abiraterone; ABI; abiraterone; ADT; androgen-deprivation therapy; Cmin; mean of trough plasma concentrations measured during the first thr
From electrochemistry to enzyme kinetics of cytochrome P450
Keywords: CYP17A1; cytochrome P450 17A1; DDAB; didodecyldimethylammonium bromide; KPi; potassium phosphate buffer; SPE; screen-printed electrode; CV; cyclic voltammetry; Cytochrome b5mc; microsomal cytochrome b5; Cytochrome b5om; mitochondrial cytochrome b5; Cytoch
PI3K pathway in prostate cancer: All resistant roads lead to PI3K
Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P
Catalytic modulation of human cytochromes P450 17A1 and P450 11B2 by phospholipid
Keywords: CYP17A1; cytochrome P450 17A1; CYP11B1; cytochrome P450 11B1; CYP11B2; cytochrome P450 11B2; POR; cytochrome P450-oxidoreductase; 12:0 PC (DLPC); 1,2-dioleoyl-sn-glycero-3-phosphocholine; 14:0 PC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; 16:0 PC; 1,2-
Effects of daily exposure to saccharin sodium and rebaudioside A on the ovarian cycle and steroidogenesis in rats
Keywords: T1R3; taste receptor type 1 subunit 3; Gα; G protein α-gustducin; T2R38; taste receptor type 2 subunit 38; GPCR; G-protein coupled receptors; PLC-β2; phospholipase C-β2; cAMP; cyclic adenosine monophosphate; FSH; follicle-stimulating hormone; LH; lute
ReviewElectrochemistry of cytochrome P450 17α-hydroxylase/17,20-lyase (P450c17)
Keywords: Steroidogenesis; Cytochrome P450c17; Androgen; Electron transfer; Mechanism; Direct electrochemistry; CYP17A1; Adrenal cortex;
Disordered zonal and cellular CYP11B2 enzyme expression in familial hyperaldosteronism type 3
Keywords: Primary aldosteronism; Aldosterone; CYP11B2; KCNJ5; CYP17A1;
CYP17A1-independent production of the neurosteroid-derived 5α-pregnan-3β,6α-diol-20-one in androgen-responsive prostate cancer cell lines under serum starvation and inhibition by Abiraterone
Keywords: 5-pregnan-3,6-diol-20-one; 4-Abiraterone; Neuroendocrine differentiation; Castration-resistant prostate cancer; CYP17A1; Neurosteroid; Steroidogenesis;
The DNA methylation status alteration of two steroidogenic genes in gonads of rare minnow after bisphenol A exposure
Keywords: Bisphenol A; cyp11a1; cyp17a1; Methylation; Gobiocypris rarus;
P450 Oxidoreductase deficiency: Analysis of mutations and polymorphisms
Keywords: Cytochrome P450 oxidoreductase; P450 oxidoreductase deficiency; PORD; Steroid metabolism; Antley-Bixler syndrome; Disorders of sexual development; CYP17A1;
CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2
Keywords: Abiraterone; CYP21A2; CYP17A1; Prostate cancer; Cytochrome P450; Steroidogenesis; Androgens;
Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis
Keywords: CYP17A1; Orteronel; Abiraterone; CYP21A2; PCOS; Premature adrenarche; Castration resistant prostate cancer;
Drospirenone intake alters plasmatic steroid levels and cyp17a1 expression in gonads of juvenile sea bass
Keywords: Progestins; Sea bass; Sex steroids; Metabolism; cyp17a1;
Clinical, hormonal, ovarian, and genetic aspects of 46,XX patients with congenital adrenal hyperplasia due to CYP17A1 defects
Keywords: CYP17A1; congenital adrenal hyperplasia; ovarian cysts; P450c17 activity deficiency; hypergonadotropic hypogonadism;
Atrazine activates multiple signaling pathways enhancing the rapid hCG-induced androgenesis in rat Leydig cells
Keywords: 22-OH cholesterol; 22(R)-hydroxycholesterol; cAMP; 3â²-5â²-cyclic adenosine monophosphate; CYP11A1; cytochrome P450C11A1; CYP17A1; cytochrome P450C17A1; ATR; atrazine; EGFR; epidermal growth factor receptor; hCG; human chorionic gonadotropin; HSD17β; 1
SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development
Keywords: AGRF; Australian genomic research facility; Amh; anti Müllerian hormone; BAC; bacterial artificial chromosome; CCL9; chemokine (C-C motif) ligand 9; CSLM; confocal laser scanning microscopy; CYP17A1; cytochrome p450 family 17, subfamily A, protein 1; Cyp
Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis
Keywords: CYP17A1; Cytochrome b5; Redox donor; Androgen synthesis; Nanodiscs; Cyt b5; cytochrome b5; Mn-b5; manganese protoporphyrin IX substituted cyt b5; DHEA; dehydroepiandrosterone; PREG; pregnenolone; OH-PREG; 17α-hydroxypregenolone;
Enantioselective endocrine disrupting effects of omeprazole studied in the H295R cell assay and by molecular modeling
Keywords: In vitro; docking; molecular dynamics; endocrine disrupting drug; enantiomers; steroidogenesis; CYP17A1; CYP19A1; CYP21A2;
T-2 toxin inhibits gene expression and activity of key steroidogenesis enzymes in mouse Leydig cells
Keywords: T-2 toxin; 3β-HSD-1; p450scc; StAR; CYP17A1; 17β-HSD; Enzyme activity; Mouse Leydig cells;
CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau
Keywords: HAPC; high altitude polycythemia; CYP17A1 gene; cytochrome P450, family 17, subfamily A, polypeptide 1 gene; CYP2E1 gene; cytochrome P450, family 2, subfamily E, polypeptide 1 gene; SNP; single nucleotide polymorphism; H b; hemoglobin; HCT; hematocrit; HW
Comparisons of Prostate Cancer Inhibitors Abiraterone and TOK-001 Binding with CYP17A1 through Molecular Dynamics
Keywords: Prostate cancer; Molecular dynamics; CYP17A1; Abiraterone; TOK-001
Cytochrome b5 modulates multiple reactions in steroidogenesis by diverse mechanisms
Keywords: Cytochrome b5; Cytochrome P450 17-hydroxylase/17,20-lyase; CYP17A1; 3β-hydroxysteroid dehydrogenase; 3βHSD; 16-ene-synthase
Novel gonadal characteristics in an aged bovine freemartin
Keywords: Anti-mullerian hormone (AMH); Bovine; CYP17A1; Freemartin; Gonad;
Limited in vitro efficacy of CYP17A1 inhibition on human castration resistant prostate cancer
Keywords: Castration-resistant prostate cancer; P45017A1; CYP17A1; Abiraterone; Liquid chromatography/mass spectrometry; C4-2AT6
Active site proton delivery and the lyase activity of human CYP17A1
Keywords: PREG; pregnenolone; OH-PREG; 17α-hydroxy-pregnenolone; PROG; progesterone; OH-PROG; 17α-hydroxy-progesterone; DHEA; dehydroepiandrosterone; AD; androstenedione; cyt-b5; cytochrome b5; Cpd I; Compound I; CYP17A1; T306A; Proton delivery; Compound I; Nucel
Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on human and rat 17α-hydroxylase/17,20-lyase activity
Keywords: Methoxychlor; HPTE; Enzyme inhibition; CYP17A1; Uncompetitive inhibition; Leydig cells;
Next-generation steroidogenesis inhibitors, dutasteride and abiraterone, attenuate but still do not eliminate androgen biosynthesis in 22RV1 cells in vitro
Keywords: DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; LHRH; luteinizing hormone releasing hormone; LH; luteinizing hormone; AR; androgen receptor; CRPC; castration resistant prostate cancer; PSA; prostate specific antigen; SRD5A1/2; 5-alpha-reductase is
Exposure to DEHP and MEHP from hatching to adulthood causes reproductive dysfunction and endocrine disruption in marine medaka (Oryzias melastigma)
Keywords: arα; androgen receptor α; BSI; brain somatic index; cyp3a; cytochrome P450 3a; cyp11b; cytochrome P450 11b; cyp17a1; cytochrome P450 17α-hydroxylase 1; cyp19; cytochrome P450 19; cyp21a; CYP450 21-α-hydroxylase; DEHP; di-(2-ethylhexyl)-phthalate; DMSO
A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
Keywords: CYP17A1; Abiraterone; Prostate cancer; Androgen; Steroidogenesis; Enzymology; Cytochrome P450;
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione
Keywords: 11KA4; 11-ketoandrostenedione; 11KT; 11-ketotestosterone; 11OH-5α-dione; 11β-hydroxy 5α-androstanedione; 11OH-AST; 11β-hydroxyandrosterone; 11OHA4; 11β-hydroxyandrostenedione; 11OHT; 11β-hydroxytestosterone; 11βHSD; 11β-hydroxysteroid dehydrogenas
Letrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary
Keywords: CYP17A1; letrozole; ovarian theca-interstitial cells; proliferation; steroidogenesis
Short CommunicationMutational screening of SF1 and WNT4 in Tunisian women with premature ovarian failure
Keywords: AMH; anti Müllerian hormone; B.M.I.; body mass index; BMP15; bone morphogenetic protein 15; CYP17A1; cytochrome P450, family 17, subfamily A, polypeptide 1; FIGLA; factor in the germline alpha; FMR1; fragile X mental retardation 1; FSH; follicle stimulat