دانلود مقالات ISI درباره Cyp1A1 + ترجمه فارسی

Triclosan activates aryl hydrocarbon receptor (AhR)-dependent apoptosis and affects Cyp1a1 and Cyp1b1 expression in mouse neocortical neurons

Keywords: Triclosan; AhR; Cyp1a1; Cyp1b1; Apoptosis; Neuron;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inflammation response and cytotoxic effects in human THP-1 cells of size-fractionated PM10 extracts in a polluted urban site

Keywords: Size-fractionated PM10; THP-1 cells; LDH; IL-8; TNFα; CYP1A1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A multiple lines of evidence approach for the ecological risk assessment of an accidental bitumen release from a steam assisted gravity drainage (SAGD) well in the Athabasca oil sands region

Keywords: AhR; Aryl hydrocarbon receptor; BTEX; benzene, toluene, ethylbenzene and xylenes; CYP1A1; Cytochrome P450 1A1; COPC; Contaminants of potential concern; EPC; Exposure point concentrations; ERA; Ecological risk assessment; EROD; Ethoxyresorufin O-deethylase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of 4-nitrophenol on expression of the ER-α and AhR signaling pathway-associated genes in the small intestine of rats

Keywords: PNP; AhR; ER-α; CYP1A1; Small intestine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Expression of CYP1A1 and CYP1A2 in the liver and kidney of rabbits after prolonged infusion of propofol

Keywords: Propofol; Propofol metabolism; Rabbit anesthesia; CYP1A1; CYP1A2; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of leads for antiproliferative activity on MDA-MB-435 human breast cancer cells through pharmacophore and CYP1A1-mediated metabolism

Keywords: CYP1A1; Metabolism based virtual screening; Pharmacophore mapping; EROD assay; Molecular docking; Molecular dynamics; Rational design; RVUMPQVYONIJNX-UHFFFAOYSA-N;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol ameliorates benzo(a)pyrene-induced testicular dysfunction and apoptosis: involvement of p38 MAPK/ATF2/iNOS signaling

Keywords: AhR; aryl hydrocarbon receptor; ATF2; activating transcription factor 2; BPDE; benzo(a)pyrene-7,8-diol-9,10-epoxide; CYP11A1; cytochrome P450 11A1; CYP1A1; cytochrome P450 1A1; iNOS; inducible nitric oxide synthase; MDA; malondialdehyde; PARP; poly-ADP ri

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Environmental monitoring of urban streams using a primary fish gill cell culture system (FIGCS)

Keywords: cyp1a1; cyp3; Metallothionein; Fish; Environmental monitoring; Cell culture; 3Rs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures

Keywords: CYP1A1; CYP1A2; Aryl hydrocarbon receptor; Pregnane X receptor; 3D culture; Spheroid; Liver cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cannabidiol induces expression of human cytochrome P450 1A1 that is possibly mediated through aryl hydrocarbon receptor signaling in HepG2 cells

Keywords: Marijuana; Cannabidiol; CYP1A1; Induction; AhR; Protein tyrosine kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line

Keywords: PAH; polycyclic aromatic hydrocarbon; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocating protein; AHH; aryl hydrocarbon hydroxylase; Hepa-1; mouse hepatoma cell line; WT; wild type; LA1; low AHH-activity, class I variant

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of the Gly45Asp variant of human cytochrome P450 1A1 using recombinant expression

Keywords: CHO; Chinese Hamster Ovary; CYPs; cytochromes P450; CYP1A1; cytochrome P450 1A1; dALA; δ-aminolevulinic acid; EDTA; ethylenediaminetetraacetic acid; ER; 7-ethoxyresorufin; EROD; 7-ethoxyresorufin O-dealkylation; EV; empty control vector; ME; β-mercaptoe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Protective effects of green tea polyphenols against benzo[a]pyrene-induced reproductive and trans-generational toxic effects in Japanese Medaka (Oryzias latipes)

Keywords: BaP; benzo[a]pyrene; GTP; green tea polyphenols; VTG; vitellogenin; CYP1A1; cytochrome P450 1A1; CYP17; cytochrome P450-17a; GSH-Px; glutathione peroxidase; RPL-7; ribosomal Protein L7; GST; glutathione (GSH) S-transferases; dph; days post hatch; BPDE; be

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Developmental toxicity of hexachloronaphthalene in Wistar rats. A role of CYP1A1 expression

Keywords: Polychlorinated naphthalenes; Rat; Embryotoxicity; Developmental toxicity; CYP1A1; Placenta;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Access channels to the buried active site control substrate specificity in CYP1A P450 enzymes

Keywords: 9MAN; 9-methyl-anthracene; ANT; anthracene; BaP; benzo[a]pyrene; BCA; bicinchoninic acid; DMF; dimethylformamide; DPHE; 9,10-dihydrophenanthrene; EFEE; 7-ethoxy-fluorescein ethyl ester; EOR; 7-ethoxy-resorufin; LC; liquid chromatography; MDS; multidimensi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Recovery of redox homeostasis altered by CuNPs in H4IIE liver cells does not reduce the cytotoxic effects of these NPs: An investigation using aryl hydrocarbon receptor (AhR) dependent antioxidant activity

Keywords: CuNP; copper nanoparticle; ROS; reactive oxygen species; AhR; aryl hydrocarbon receptor; ßNF; ß-Naphthoflavone; αNF; α-Naphthoflavone; GST; glutathione-S-transferase; GSH; glutathione; GSSG; oxidised glutathione; Nrf2; nuclear factor erythroid-2-relat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Litchi chinensis: medicinal uses, phytochemistry, and pharmacology

Keywords: Aq; aqueous; A549; human lung cancer; ABTS; 2,2′-Azinobis(3-ethylbenzothiazoline-6-sulfonate); ADP; adenosine diphosphate; AGS; human gastric epithelial; ADPRTL1; ADP-ribosyltransferase (NAD+poly (ADP-ribose) polymerase)-like 1); ADAM9; metalloproteinas

دانلود رایگان متن کامل مقاله ISI 106 صفحه سال انتشار : 2015 سفارش ترجمه

The Cytochrome P4501A1 gene polymorphisms and idiopathic male infertility risk: A meta-analysis

Keywords: CYP1A1; Cytochrome P4501A1; SNPs; single-nucleotide polymorphisms; CI; confidence interval; OR; odds ratio; CYP1A1 male infertility; Meta-analysis; Polymorphism;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infection

Keywords: CYP1A1; GSTT1; GSTM1; Host genetics; ALTS;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Detoxification enzyme activities (CYP1A1 and GST) in the skin of humpback whales as a function of organochlorine burdens and migration status

Keywords: Southern hemisphere humpback whales (Megaptera novaeangliae); Epidermal enzyme activity; CYP1A1; GST; Persistent organic pollutants; Antarctica

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs

Keywords: DDT (PubChem CID: 3036); Benzo[a]pyrene (PubChem CID: 611); 3-Methylcholanthrene (PubChem CID: 1674)miRNA; DDT; PAH; Benzo[a]pyrene; 3-Methylcholanthrene; Rat; CYP1A1; CYP2B1; Expression level

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes

Keywords: Alkaloid; Palmatine; Cytochrome P450; CYP1A1; Aryl hydrocarbon receptor; Herb-drug interactions;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node

Keywords: AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; B(a)P; benzo(a)pyrene; bHLH/PAS; basic helix-loop-helix/PER-ARNT-SIM; CoCl2; cobalt chloride; CYP1A1; cytochrome P450 1A1; HIF-1α; hypoxia-inducible factor-1α; HRE; hy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer in a North Indian population

Keywords: SNP; Cervical cancer; CYP1A1; North India; PCR-RFLP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol

Keywords: CBD, cannabidiol; CBDHQ, CBD-hydroxyquinone; CBDM, CBD-2′-monomethyl ether; CBDD, CBD-2′,6′-dimethyl ether; CBDV, cannabidivarin; CYP, cytochrome P450; EROD, 7-ethoxyresorufin O-deethylaseCannabidiol; CYP1A1; Inactivation; Mechanism-based inhibition; Stru

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Influence of CYP1A1*2C on High Triglyceride Levels in Female Mexican Indigenous Tarahumaras

Keywords: High triglyceride levels; Tarahumaras; Tepehuanos; CYP1A1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Aryl hydrocarbon receptor protein and Cyp1A1 gene induction by LPS and phenanthrene in Atlantic cod (Gadus morhua) head kidney cells

Keywords: Pheneanthrene; AhR; CYP1A1; LPS; poly I:C;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Time course of bronchial cell inflammation following exposure to diesel particulate matter using a modified EAVES

Keywords: In vitro; Bronchial; Diesel particulate matter; EAVES; CYP1A1; IL-8;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Altered gene expression in HepG2 cells exposed to a methanolic coal dust extract

Keywords: Genotoxicity; Comet assay; Transcriptional changes; NQO1; CYP1A1; GAPDD45B

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

Keywords: AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; bHLH/PAS; basic helix-loop-helix/PER-ARNT-SIM; ChIP; chromatin immunoprecipitation; CYP1A1; cytochrome P450 1A1; DMSO; dimethyl sulfoxide; EMSA; electrophoretic mobility

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of individual polychlorinated naphthalene (PCN) components of Halowax 1051 and two defined, artificial PCN mixtures on AHR and CYP1A1 protein expression, steroid secretion and expression of enzymes involved in steroidogenesis (CYP17, 17β-HSD and C

Keywords: Halowax 1051; PCN; Ovary; Steroidogenesis; CYP1A1; AHR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides

Keywords: AhR; aryl hydrocarbon receptor; ABZSO; albendazole sulfoxide; ARNT; aryl hydrocarbon receptor nuclear translocator; CALUX assay; chemical activated luciferase gene expression assay; CYP1A1; cytochrome P450 1A1; DRE; dioxin response element; MDCKII cells;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Combining metabolomic analysis and microarray gene expression analysis in the characterization of the medicinal plant Chelidonium majus L

Keywords: Chelidonii herba; Herbal safety; Gene expression profiling; 1H-NMR fingerprint; IPA; Ingenuity pathway analysis; PCA; Principal component analysis; qRT-PCR; quantitative real-time PCR; AhRR; Aryl-hydrocarbon receptor repressor; AKR1B10; Aldo-keto reductas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

CYP1A1 and CYP1B1-Mediated Biotransformation of the Antitrypanosomal Methamidoxime Prodrug DB844 Forms Novel Metabolites Through Intramolecular Rearrangement

Keywords: CYP1A1; CYP1B1; cytochrome P450; intramolecular rearrangement; drug metabolism; prodrugs; human African trypanosomiasis; nitric oxide; CID, collision-induced dissociation; CNS, central nervous system; CYP, cytochrome P450; HAT, human African trypanosomias

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down

Keywords: AhR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon repressor protein; α-NF; α-naphthoflavone; β-NF; β-naphthoflavone; CYP1A1; cytochrome P450 1A1; ITE; 2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester; TCDD; 2,3,7,8-tetrachlo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat

Keywords: AA; arachidonic acid; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ALP; alkaline phosphatase; CAR; constitutive androstane receptor; Cyp1a1; P450 family 1 subfamily a, polypepti

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms

Keywords: AhR; aryl hydrocarbon receptor; ARE; antioxidant-responsive element; As(III); arsenite; CYP1A1; cytochrome P450 1A1; NQO1; NADP(H):quinone oxidoreductase; Nrf2; nuclear factor-erythroid 2 p45-related factor 2; SUL; sulforaphane; TCDD; 2,3,7,8-tetrachlorod

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Association between the CYP1A1 T3801C polymorphism and risk of cancer: Evidence from 268 case-control studies

Keywords: PAHs; polycyclic aromatic hydrocarbons; CYP; cytochrome P450; CYP1A1; cytochrome P450 1A1; SNP; single nucleotide polymorphism; OR; odds ratios; HWE; Hardy-Weinberg equilibrium; NSCLC; non-small cells lung cancer; AC; adenocarcinoma; SCC; squamous cell

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه

Dephosphorylation of Sp1 at Ser-59 by Protein Phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole

Keywords: Sp1; Protein phophatase 2A; CYP1A1; Aryl hydrocarbon receptor;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins

Keywords: NAD(P)H:quinone oxidoreductase-1 (NQO1); Cytochrome P450 1B1 (CYP1B1); CYP1A1; Subcellular localization; Mitochondrial targeting; Endoplasmic reticulum targeting; Dioxin-inducible enzymes; Mouse tissues (lung, spleen, uterus, small intestine, liver, kidne

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

β-Catenin signaling induces CYP1A1 expression by disrupting adherens junctions in Caco-2 human colon carcinoma cells

Keywords: ARNT; Ah receptor nuclear translocator; bHLH; basic helix-loop-helix; CTF2; E-cadherin carboxy terminal fragment 2; CYP1A1; cytochrome P-450 1A1; DAPT; N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester; EMT; epithelial-mesenchymal tr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Black soybean seed coat polyphenols prevent B(a)P-induced DNA damage through modulating drug-metabolizing enzymes in HepG2 cells and ICR mice

Keywords: BE; black soybean seed coat extract; C3G; cyanidin 3-glucoside; PC; procyanidin; PC-rich BE; procyanidins rich black soybean seed coat extract; EC; (−)-epicatechin; B(a)P; benzo[a]pyrene; MN assay; micronucleus assay; CYP1A1; cytochrome P4501A1; GST; gl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments

Keywords: 27K BeadChip; Air pollution; Bronchial asthma; Children; DNA methylation pattern; 5-mC; 5-methyl-cytosine; ACSL3; CoA synthetase long-chain family member 3 gene; ADRB2; beta-2 adrenergic receptor; AHRR; aryl hydrocarbon receptor repressor; B[a]P; benzo[a]

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Functional CYP1A1 genetic variants, alone and in combination with smoking, contribute to development of head and neck cancers

Keywords: CYP1A1; Polymorphism; Head and neck cancer; Susceptibility; Smoking;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA changes associated with atypical CYP1A1 inducer BMS-764459

Keywords: miRNA; AhR; CYP1A1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Cytoprotective effect of epigallocatechin-3-gallate against deoxynivalenol-induced toxicity through anti-oxidative and anti-inflammatory mechanisms in HT-29 cells

Keywords: AHH; aryl hydrocarbon hydroxylase; ANOVA; analysis of variance; AO/EB; acridine orange/ethidium bromide; CAT; catalase; CCCP; carbonyl cyanide m-chlorophenylhydrazone; COX-2; cyclooxygenase-2; CYP1A1; cytochrome P4501A1; DAB; diaminobenzidine; DCF; 2′,7

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic association of aromatic hydrocarbon receptor (AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorphisms with dioxin blood concentrations among pregnant Japanese women

Keywords: PCDD; polychlorinated dibenzo-p-dioxin; PCDF; polychlorinated dibenzofuran; PCB; polychlorinated biphenyl; TEQ; toxicity equivalence quantity; AHR; aromatic hydrocarbon receptor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; CYP1A1; cytochrome P450, family 1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

TCDD induces the expression of insulin-like growth factor binding protein 4 in 5L rat hepatoma cells: A cautionary tale of the use of this cell line in studies on dioxin toxicity

Keywords: AhR; aryl hydrocarbon receptor; AKT1S1; proline-rich AKT1 substrate 1; CYP1A1; cytochrome P450 1A1; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; ERK; extracellular signal-regulated protein kinase; GSK3; glycogen synthase kinase 3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Risk of renal cell carcinoma and polymorphism in phase I xenobiotic metabolizing CYP1A1 and CYP2D6 enzymes

Keywords: CYP1A1; CYP2D6; Xenobiotic metabolizing enzyme; Renal cell carcinoma; AJCC cancer stage; Fuhrman's grade

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population

Keywords: Lung cancer; CYP1A1; CYP2A6; CHRNA5; Smokers; Bangladeshi population

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه