دانلود مقالات ISI درباره Cyp1A2 + ترجمه فارسی

Glutathione S-transferase M1 and T1, CYP1A2-2467T/delT polymorphisms and non small-cell lung cancer risk in Tunisian sample

Keywords: GSTT1; GSTTM1; CYP1A2; Polymorphisms; Lung cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

AhrdCyp1a2(−/−) mice show increased susceptibility to PCB-induced developmental neurotoxicity

Keywords: Polychlorinated biphenyls; PCBs; CYP1A2; Aryl hydrocarbon receptor; Developmental neurotoxicity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Riluzole prodrugs for melanoma and ALS: Design, synthesis, and in vitro metabolic profiling

Keywords: Riluzole; Prodrug; Cancer; Melanoma; Cyp1A2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Cross-sectional study of hepatic CYP1A and CYP3A enzymes in hybrid striped bass, channel catfish and Nile tilapia following oxytetracycline treatment

Keywords: BFC, 7-benzyloxy-4-trifluoromethylcoumarin; BzRes, resorufin benzyl ether; CEC, 3-cyano-ethoxycoumarin; CYP, cytochrome P450; EROD, 7-ethoxyresorufin O-deethylaseHybrid striped bass; Channel catfish; Nile tilapia; Oxytetracycline; CYP450; CYP1A1; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1

Keywords: P450; CYP1A1; CYP1A2; CYP1B1; trans-Stilbene derivatives; Molecular docking

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms

Keywords: Radix Astragali; Radix Rehmanniae; CYP1A2; CYP2C9; CYP2D6; CYP2E1; CYP3A4; Human liver microsomes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

MG132 Alleviates Liver Injury Induced by Intestinal Ischemia/Reperfusion in Rats: Involvement of the AhR and NFκB Pathways

Keywords: AhR; MG132; liver injury; intestinal ischemia/reperfusion; cyp1a2; IκBα; NFκBp65

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of cytochrome P450 2D6 and 2C9 substrates and inhibitors by QSAR analysis

Keywords: CYP; cytochrome P450; CYP2C9; cytochrome P450 subtype 2C9; CYP2D6; cytochrome P450 subtype 2D6; CYP1A2; cytochrome P450 subtype 1A2; CYP2C19; cytochrome P450 subtype 2C19; CYP3A4; cytochrome P450 subtype 3A4; PLR; partial logistic regression; PLS; partial

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Clock gene mPer2 functions in diurnal variation of acetaminophen induced hepatotoxicity in mice

Keywords: Acetaminophen; Period 2; Cyp1a2; Circadian; Mice

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Simultaneous measurement of CYP1A2 activity, regioselectivity, and coupling: Implications for environmental sensitivity of enzyme-substrate binding

Keywords: P450 regioselectivity; P450 coupling; CYP1A2; Cyanocoumarin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line

Keywords: CYP; cytochrome P450; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; DRE; dioxin response element; EROD; 7-ethoxyresorufin O-deethylation; B[a]P; benzo[a]pyrene; BNF; β-naphthoflavone; TIIA; tanshinone IIA; CTS; cry

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation

Keywords: ACN; acetonitrile; APAP; acetaminophen; CYP1A2; cytochrome P450 1A2 enzyme; CYP2B6; cytochrome P450 2B6 enzyme; CYP2C19; cytochrome P450 2C19 enzyme; CYP2D6; cytochrome P450 2D6 enzyme; CYP3A4; cytochrome P450 3A4 enzyme; CYP450; cytochrome P450 enzymes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD

Keywords: COPD; CYP1A1; CYP1A2; CYBA; PolymorphismCOPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in one second; CYP, cytochrome P450 oxidase; LPO, lipid peroxidation; MDA, malondialdehyde; CAT, catalase; GSH, reduced glutathione; GPx, g

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro

Keywords: Danshen (Salvia miltiorrhiza); Tanshinones; CYP1A2; CYP2C9; CYP2E1; CYP3A4; Human liver microsomes; In vitro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice

Keywords: 2,3,7,8-Tetrachlorodibenzo-p-dioxin; TCDD; CYP1A2; Knockout mice; Metabolism; Mouse major urinary protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells

Keywords: Flavonoids; CYP1A1; CYP1B1; CYP1A2; MDA-MB-468 cells; Metabolism

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The effect of isothiocyanates on CYP1A1 and CYP1A2 activities induced by polycyclic aromatic hydrocarbons in Mcf7 cells

Keywords: Polycyclic aromatic hydrocarbons; Isothiocyanates; CYP1A1; CYP1A2; Inhibition; ChemopreventionAhR, aryl hydrocarbon receptor; ANT, anthracene; ARNT, aryl hydrocarbon receptor nuclear translocator; BSA, bovine serum albumin; DBA, dibenzo[a,h]anthracene; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes

Keywords: Chemoprevention; SR13668; 9-cis-UAB30; Pentamethylchromanol; Human hepatocytes; CYP1A2; CYP2B6; CYP3A4

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on rat CYP1A2 expression and metabolism of model CYP1A2 probe substrates

Keywords: Danshen; Tanshinones; CYP1A2; Expression; Competitive inhibition of CYP1A2 probes

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

A novel gender-related difference in the constitutive expression of hepatic cytochrome P4501A subfamily enzymes in Meishan pigs

Keywords: Cytochrome P450; CYP1A1; CYP1A2; Sex-difference; Liver; Meishan pigs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements

Keywords: CYP1A1; CYP1A2; Omeprazole; Gene transcription; Aryl hydrocarbon receptor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley–Bixler syndrome variants of cytochrome P450 oxidoreductase

Keywords: NADPH-cytochrome P450 oxidoreductase; Antley–Bixler syndrome; POR; Polymorphism; Cytochrome P450; CYP1A2; P450 1A2; Protein–protein interaction; Drug-metabolizing enzymes; Adverse drug reactions

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Analytical approaches to determine cytochrome P450 inhibitory potential of new chemical entities in drug discovery

Keywords: In vitro cytochrome P450 inhibition assay; LC–MS/MS; DDI; Cocktail DDI analysis; Bioanalysis; CYP3A4; CYP2D6; CYP2C19; CYP2C9; CYP1A2; High-throughput analysis; Drug discovery

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

A combinatorial approach to substrate discrimination in the P450 CYP1A subfamily

Keywords: Multivariate statistic; CYP1A1; CYP1A2; Mutant; DNA shuffling; Random mutagenesis; Resorufin; Fluorescein; ProSAR

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Evidences for CYP3A4 autoactivation in the desulfuration of dimethoate by the human liver

Keywords: Dimethoate; Omethoate; Organophosphorothionate pesticides; CYP1A2; CYP3A4; Autoactivation; Atypical kinetics

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs

Keywords: Naphthalene; Aryl hydrocarbon receptor; 2,3,7,8-Tetrachlorodibenzo[p]dioxin (TCDD); Bioactivation; CYP1A1; CYP1A2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

In vitro metabolic studies on the selective metabotropic glutamate receptor sub-type 5 (mGluR5) antagonist 3-[(2-methyl-1,3-thiazol-4-yl) ethynyl]-pyridine (MTEP)

Keywords: Metabotropic glutamate receptor; Drug metabolism; CYP1A2; CYP2C; MPEP; MTEP

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens

Keywords: Magnolol; Anti-mutagenic activity; Indirect mutagens; Direct mutagens; CYP1A1; CYP1A2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of quercetin on β-apo-8′-carotenal-induced DNA damage and cytochrome P1A2 expression in A549 cells

Keywords: β-Carotene; β-Apo-8′-carotenal; Quercetin; Benzo[a]pyrene; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Pharmacokinetics of Oltipraz in Mutant Nagase Analbuminemic Rats

Keywords: oltipraz; mutant Nagase analbuminemic rats; CYP1A2; pharmacokinetics; protein binding; metabolism; CYP enzymes;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Metabolism of the A1 adenosine receptor PET ligand [18F]CPFPX by CYP1A2: implications for bolus/infusion PET studies

Keywords: CPFPX; CYP1A2; Radio-TLC; PET; Fluvoxamine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

The expressions of protooncogenes and CYP1A in lungs of rats exposed to sulfur dioxide and benzo(a)pyrene

Keywords: Sulfur dioxide; Benzo(a)pyrene; CYP1A1; CYP1A2; c-Jun; c-Fos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: Identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1

Keywords: Bilobalide; Cytochrome P450; CYP1A1; CYP1A2; CYP1B1; Ginkgo biloba; Ginkgolide A; Ginkgolide B; Ginkgolide C; Ginkgolide J; Isorhamnetin; Kaempferol; Quercetin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine

Keywords: Alkylguanine; DNA alkyltransferase; O6-Benzylguanine; Molecular imaging; CYP1A2; Nucleoside transporter

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: A pilot study comparing pre- and post-operative levels

Keywords: 2-Hydroxyestrogen; 16α-Hydroxyestrone; Breast cancer; Tamoxifen; Radiotherapy; CYP1A2; Polymorphism; Coffee; Alcohol; Prognosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Benzo(α)pyrene-induced up-regulation of CYP1A2 gene expression: Role of adrenoceptor-linked signaling pathways

Keywords: Benzo(α)pyrene; CYP1A2; Catecholamines; Adrenoceptors; Rat

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

cDNA cloning and characterization of feline CYP1A1 and CYP1A2

Keywords: Cat; Cytochrome P450 (CYP); CYP1A1; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) rat hepatocarcinogenesis by caffeine, a CYP1A2 inducer, points to complex counteracting influences

Keywords: MeIQx; Caffeine; CYP1A2; NAT2; Syndecan-2; p21; CDK4MeIQx, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline; GST-P, glutathione-S transferase placental form; HCA, heterocyclic amine; CYP, cytochrome P450; Sdc2, syndecan-2; NAT, N-acetyltransferase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Induction of Human CYP1A2 and CYP3A4 in Primary Culture of Hepatocytes from Chimeric Mice with Humanized Liver

Keywords: chimeric mouse liver; human hepatocytes; CYP1A2; CYP3A4; induction; real-time RT-PCR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole

Keywords: Safrole; Human; CYP1A2; CYP2A6; CYP2E1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Rat hepatic CYP1A1 and CYP1A2 induction by menadione

Keywords: Menadione; CYP1A1; CYP1A2; Induction in vivo;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

The CYP1A2-164A→C polymorphism (CYP1A2*1F) is associated with the risk for colorectal adenomas in humans

Keywords: Heterocyclic aromatic amines; CYP1A2; Polymorphism; Colorectal cancer risk; Adenomas;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Caffeine Metabolism, Genetics, and Perinatal Outcomes: A Review of Exposure Assessment Considerations during Pregnancy

Keywords: Caffeine; Cytochrome P450 1A2; CYP1A2; Genetic Polymorphisms; Pregnancy; Reproduction; Fetal Growth Retardation; Gestational Age; Spontaneous Abortion; AAMU; 5-acetyl-6-amino-3-methyluracil; AFMU; 5-acetylamino-6-formylamino-3-methyluracil; CYP1A2; cytoch

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Influence of the genetic polymorphism in the 5′-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers

Keywords: AAs; aromatic amines; AFMU; 5-acetylamino-6-formyl-amino-3-methyluracil; CYP1A2; cytochrome P450 1A2; CMR; caffeine metabolic ratio; HAs; aromatic and heterocyclic amines; NA; nitrosamine; PAHs; polycyclic aromatic hydrocarbons; SNPs; single nucleotide po

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Activation of CYP1A1 gene expression during primary culture of mouse hepatocytes

Keywords: AhR; aryl hydrocarbon receptor; Arnt; aryl hydrocarbon receptor nuclear translocator protein; CYP; cytochrome P450; cDNA; complementary DNA; DCFH-DA; 2,7-dichrolofluorescin diacetate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Hsp; heat shock protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of sulfur dioxide inhalation on CYP1A1 and CYP1A2 in rat liver and lung

Keywords: Sulfur dioxide; Liver; Lung; CYP1A1; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

NAT2 fast acetylator genotype is associated with an increased risk of lung cancer among never-smoking women in Taiwan

Keywords: NAT2; CYP1A2; Never-smoking; Females; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Pharmacokinetics of theophylline in diabetes mellitus rats: Induction of CYP1A2 and CYP2E1 on 1,3-dimethyluric acid formation

Keywords: Theophylline; 1,3-DMU; CYP1A2; CYP2E1; Pharmacokinetics; Diabetes mellitus; Alloxan; Streptozotocin; Rats;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Single Nucleotide Polymorphisms and Haplotypes of CYP1A2 in a Japanese Population

Keywords: CYP1A2; SNP; haplotype; Japanese;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Cell-based high-throughput bioassays to assess induction and inhibition of CYP1A enzymes

Keywords: CYP1A; CYP1A2; Induction; Reporter gene assay; Cell line; Drug-drug interactions; Drug-carcinogen interactions; Drug-herbal interactions; DRE, dioxin response element; RLUs, relative luciferase light units; PAH, polycyclic aromatic hydrocarbon; TCDD, 2,3,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه