Keywords: 27-HC; 27-hydroxycholesterol; ER; estrogen receptor; CYP27A1; cytochrome P450, family 27, subfamily A, polypeptide 1; LXR; liver X receptor; BRCA1 and BRCA2; Breast cancer 1 and 2; LDL; low density lipoprotein; HDL; high density lipoprotein; ApoE; apolipo
مقالات ISI (ترجمه نشده)
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Keywords: Acadl; acyl-CoA dehydrogenase, long chain; Acadvl; acyl-CoA dehydrogenase, very long chain; Acaca; acetyl-CoA carboxylase alpha; Abcb11; ATP binding cassette subfamily B member 11; Abcg5; ATP binding cassette subfamily G member 5; Abcg8; ATP binding casse
Keywords: 4-HNE; 4-HydroxyNonenal; AD; Alzheimer's Disease; AICD; Amino-terminal APP Intra Cellular Domain; ApoE; Apolipoprotein E; APP; Amyloid Precursor Protein; ATP; Adenosine TriPhosphate; Aβ; Amyloid beta peptide; AβDP; Aβ-Degrading Proteases; CNS; Centra
Keywords: 27-HC; 27-Hydroxycholesterol; 3PO; 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; ABCG1; ATP-binding cassette subfamily G1; ACBA1; ATP-binding cassette subfamily A1; ACC1; Acetyl-Co-A carboxylase-1; AKAP4; A-kinase anchoring protein 4; ALDO; Aldolase; AM
Keywords: ASBT; apical sodium-dependent bile acid transporter; ASDs; amorphous solid dispersions; BACS; bile acid-CoA synthase; BAT; bile acid-amino acid transferase; BCS; biopharmaceutics classification system; BSH; bile salt hydrolase; C4; 7α-hydroxy-4-cholesten
Self-packed core shell nano liquid chromatography columns and silica-based monolithic trap columns for targeted proteomics
Keywords: Column packing; Silica monolith; Core shell particles; Nano; Liquid chromatography; CYP27A1; Targeted proteomics;
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer
Keywords: 27-OHC; 27-hydroxycholesterol; ADT; androgen deprivation therapy; AR; androgen receptor; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; C/EBP; CCAAT / Enhancer binding proteins; CHOP; C/EBP homologous protein; CIP2A; can
Keywords: Bile Acids; FXR; TGR5; Meta-Inflammation; apo; apolipoprotein; ASBT; apical sodiumâdependent bile acid transporter; BA; bile acid; BAS; bile acid sequestrant; BAT; brown adipose tissue; BSH; bile salt hydrolase; CA; cholic acid; CCK; cholecystokinin; CD
Keywords: NAFLD; Non-Alcoholic Fatty Liver Disease; NAFL; Non-Alcoholic Fatty Liver; NASH; Non-Alcoholic SteatoHepatitis; FA; fatty acids; TG; triglycerides; SFA; saturated fatty acids; CYP; cytochrome; HFA; high fatty acids; HCh; high cholesterol; ALT; alanine ami
Keywords: Cerebrotendinous xanthomatosis; Xanthoma; Cholestanol; CYP27A1; Sterol 27-hydroxylase;
Keywords: 24OHC; 24S-Hydroxycholesterol; 27OHC; 27-Hydroxycholesterol; ABC; ATP-binding cassette transporter; ACAT; Acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; ApoE; Apolipoprotein E; BACHD; Bacterial artificial chromosome HD; BDNF; Brain-derived n
Keywords: ABC; ATP binding cassette; ACAT; Acyl CoA: cholesterol acyltransferase; ACBD1/3; acyl CoA binding domain 1/3; AFG3L2; AFG3-like AAA ATPase 2; AIM/Spα; apoptosis inhibitor expressed by macrophages; ANT; adenine nucleotide transporter; Apo; apolipoprotein;
Keywords: ASBT; apical sodium dependent transporter; AKT; protein kinase B; BSEP; bile salt export protein (ABCB11); CA; cholic acid; CCA; cholangiocarcinoma; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; CYP7B1; oxysterol 7α-hydroxylase; CYP27
Keywords: Cholesterol; Oxysterol; CYP46A1; CYP27A1; CYP3A4; CYP39A1; CYP7B1; CH25H; Cholesterol 7α-hydroxylase; Sterol 27-hydroxylase; Cholesterol 24-hydroxylase; Cholesterol 25-hydroxylase; Oxysterol 7α-hydroxylase; 24-hydroxycholesterol 7α-hydroxylase; Epigene
The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17α-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats
Keywords: Asbt; apical sodium-dependent bile acids transporter; ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate transaminase; BAs; bile acids; Bsep/BSEP; bile salt export pump; β-MCA; β-muricholic acid; CA; cholic acid; CDCA; chenodeoxycholic
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Lysophosphatidylcholine induces expression of genes involved in cholesterol biosynthesis in THP-1 derived macrophages
Keywords: LPC; lysophosphatidylcholine; PCA; principal component analysis; FFA; free fatty acids; DMSO; dimethyl sulfoxide; FPKM; fragments per kilobase of transcript per million fragments mapped; RT-PCR; reverse transcription polymerase chain reaction; KEGG; Kyoto
CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites
Keywords: CYP; cytochrome P450; 7DHC; 7-dehydrocholesterol; 20,22(OH)2L3; 20,22-dihydroxylumisterol3; HP-β-CD; 2-hydroxypropyl-β-cyclodextrin; 25(OH)D3; 25-hydroxyvitamin D3; 22(OH)L3; 22-hydroxylumisterol3; 24(OH)L3; 24-hydroxylumisterol3; 25(OH)L3; 25-hydroxylu
Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation
Keywords: SREBP; sterol regulator element-binding protein; HMGCR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; CYP7A1; cholesterol-7alpha-hydroxylase; CYP27A1; cholesterol-27alpha-hydroxylase; ACAT1; acetyl-CoA cholesterol acyltransferase 1; LDLR; low density l
The interrelationship between bile acid and vitamin A homeostasis
Keywords: ATGL; Adipose triglyceride lipase; ADH; Alcohol dehydrogenase; ALD; Alcoholic liver disease; atRA; All-trans retinoic acid; ASBT/SLC10A2; Apical sodium-dependent bile salt transporter; ABCA1; ATP-binding cassette transporter member 1; BCMO1; Beta-carotene
Diet-induced obesity and weight loss alter bile acid concentrations and bile acid-sensitive gene expression in insulin target tissues of C57BL/6J mice
Keywords: Bile acids; Obesity; Weight loss; Gene expression; Mice; Abcc3; ATP binding cassette subfamily C member 3; Acox2; peroxisomal branched chain acyl-CoA oxidase; Amacr; α-methylacyl-CoA racemase; ANOVA; analysis of variance; BA; bile acids; Bal; bile acid C
Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis
Keywords: 24S-OHC; 24(S)-hydroxycholesterol; Apoe; apolipoprotein E; CNS; central nervous system; Cyp27a1; cholesterol 27-hydroxylase; Cyp46a1; cholesterol 24-hydroxylase; Hmgcr; 3-hydroxy-3-methylglutaryl-CoA reductase; Mecp2; methyl CpG-binding protein 2; SC4mol;
Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells
Keywords: ARE; antioxidant response element; CYP27A1; 27-hydroxylase; DAPI; 4,6-diamidino-2-phenylindole; DPI; diphenyleneiodonium chloride; ERK; extracellular signal-regulated kinase; GPx; glutathione peroxidase; GSR; glutathione reductase; HO-1; heme oxygenase-1;
Expression of human CYP27A1 in B. megaterium for the efficient hydroxylation of cholesterol, vitamin D3 and 7-dehydrocholesterol
Keywords: CYP27A1; Cytochrome P450; Bacillus megaterium; Vitamin D3; Cholesterol; 7-Dehydrocholesterol;
Mesenchymal stem cells: In vivo therapeutic application ameliorates carbon tetrachloride induced liver fibrosis in rats
Keywords: ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate transaminase; BM; bone marrow; Bsep; bile salt export pump; CCl4; carbon tetrachloride; CYP27A1; Mitochondrial sterol 27-hydroxylase; CYP7A1; microsomal cholesterol 7α-hydroxylase; DMEM
Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1
Keywords: ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; bw; body weight; Cav-1; Caveolin-1; EC; esterified cholesterol; CYP27A1; sterol-27 hydroxylase; FVB; Friend Leukemia Virus; LAL; lysosomal acid lipase; Npc1; Niemannâ
Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation
Keywords: Bcl-2; B-cell lymphoma 2; CYP27A1; 27-hydroxylase; DHE; dihydroethidium; ERK; extracellular signal-regulated kinase; HRP; horseradish peroxidase; JC-1; 5,5â²,6,6â²-tetrachloro1,1â²,3,3â²-tetraethylbenzimidazolylcarbocyanine iodide; 7Â K; 7-ketocholest
Mutation in CYP27A1 identified in family with coronary artery disease
Keywords: Coronary artery disease; Exome sequencing; CYP27A1; Reverse cholesterol transport;
Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis
Keywords: StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases
Keywords: LXR; Oxysterols; Dementia; Biomarker; Mass spectrometry; 24OHC; 24S-hydroxycholesterol; 27OHC; 27-hydroxycholesterol; Aβ; amyloid beta; ABC; ATP-binding cassette transporter; ACAT; acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; Apoe; apolip
Three siblings with Cerebrotendinous Xanthomatosis: A novel mutation in the CYP27A1 gene
Keywords: Cerebrotendinous Xanthomatosis; CYP27A1
Vitamin D 25-hydroxylase – Four decades of searching, are we there yet?
Keywords: Cytochrome P450 enzymes; CYP27A1; CYP2R1; CYP2J2/3; CYP3A4; CYP2D25; CYP2C11
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1
Keywords: CYP11A1; CYP27A1; CYP46A1; Retina; Retinal pigment epithelium; Cholesterol; 5-Cholestenoic acid; 22R-Hydroxycholesterol; Phospholipids; A2E
Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge
Keywords: Cholestanol; CYP27A1; CYP7A1; 7α-Hydroxy-4-cholesten-3-one
Berberine and plant stanols synergistically inhibit cholesterol absorption in hamsters
Keywords: ABCG; ATP-binding cassette superfamily G; BBR; berberine chloride; BBRPS; combination of BBR and plant stanols; BW; body weight; CT; control; FSR; free cholesterol fractional synthesis rate; CYP7A1; cholesterol-7α-hydroxylase; CYP27A1; sterol 27-hydroxla
Expression of the vitamin D receptor, 25-hydroxylases, 1α-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
Keywords: Vitamin D; Kidney; Cancer; CYP2R1; CYP27A1
Marked variability in hepatic expression of cytochromes CYP7A1 and CYP27A1 as compared to cerebral CYP46A1. Lessons from a dietary study with omega 3 fatty acids in hamsters
Keywords: Fish oil; n-3 polyunsaturated fatty acids; American Heart Association; Dietary guidelines; Cholesterol turnover; Brain; CYP7A1; CYP27A1; CYP46A1
Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones
Keywords: Benzylidene tetralones; Benzyl tetralones; CYP24A1; CYP27A1; Enzyme inhibition; Molecular modelling
Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids
Keywords: AA; arachidonic acid; ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; apoA1; apolipoproteinA1; apoE; apolipoproteinE; BSA; bovine serum albumin; CE; carboxylesterase; CES1; carboxylesterase 1; CES2; carboxylesterase
Oxysterols: Novel biologic roles for the 21st century
Keywords: Oxysterols; Hedgehog proteins; Fetal development; Photoxidation; Retina metabolism; CYP27A1; CYP46A1; Sulfotransferases
Monocyte-derived cells express CYP27A1 and convert vitamin D3 into its active metabolite
Keywords: Monocyte; Macrophage; Dendritic cell; Active vitamin D3; CYP27A1; CYP27B1; CYP24A1
Gene expression profiling identifies retinoids as potent inducers of macrophage lipid efflux
Keywords: Retinoid; Macrophage; Lipid efflux; CYP27A1; ABC transporter;
Regulation of sterol 27-hydroxylase in human monocyte-derived macrophages: up-regulation by transforming growth factor β1
Keywords: 27-Hydroxycholesterol; 3β-Hydroxy-5-cholestenoic acid; CYP27A1; Cholesterol;
The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors
Keywords: ASBT; apical sodium-dependent bile acid transporter; I-BABP; ileal bile acid-binding protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27A1; sterol 27-hydroxylase; CYP8B1; sterol 12α-hydroxylase; PPAR; peroxisome proliferator-activated receptors; RXR; ret