دانلود مقالات ISI درباره Cyp2C19 + ترجمه فارسی

A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production

Keywords: AO; aldehyde oxidase; ANA; antinuclear antibody; AADAC; arylacetamide deacetylase; BNPP; bis(4-nitrophenyl)phosphate; CES; carboxylesterase; CYP; cytochrome P450; DTNB; 5,5′-dithiobis(2-nitrobenzoic acid); EDTA; ethylenediamine-N,N,N′N′-tetraacetic

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of CYP2C19 allele and genotype frequencies in Iranian population using experimental and computational approaches

Keywords: Cardiovascular diseases; Clopidogrel; CYP2C19; Meta-analysis; Population structure; Single nucleotide polymorphism;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Combinations of fragment descriptors for improved prediction of CYP2C19 inhibitors

Keywords: CYP2C19; Inhibitor; Classification; Fragment; Support vector machine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

ABCB1 C3435T and CYP2C19*2 polymorphisms in a Palestinian and Turkish population: A pharmacogenetic perspective to clopidogrel

Keywords: Clopidogrel; ABCB1; CYP2C19; Palestinian; Turkish; SNP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

VASP phosphorylation and genetic polymorphism for clopidogrel resistance in Chinese patients with non-cardioembolic ischemic stroke

Keywords: Vasodilator stimulated phosphoprotein; Clopidogrel resistance; CYP2C19; CYP3A4; Non-cardioembolic ischemic stroke;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Regular ArticleImpact of point-of-care testing for CYP2C19 on platelet inhibition in patients with acute coronary syndrome and early dual antiplatelet therapy in the emergency setting

Keywords: CYP2C19; Pharmacogenetics; Clopidogrel; Prasugrel; Ticagrelor; Acute coronary syndrome;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Efficacy and safety of voriconazole and CYP2C19 polymorphism for optimised dosage regimens in patients with invasive fungal infections

Keywords: Voriconazole; Efficacy; Safety; Hepatotoxicity; CYP2C19; Trough plasma concentrations

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Regular ArticleImpact of CYP2C19 Polymorphism and Proton Pump Inhibitors on Platelet Reactivity to Clopidogrel and Clinical Outcomes Following Stent Implantation

Keywords: CYP2C19; Cytochrome P450 2C19 enzyme; CHD; coronary heart disease; FDA; Food and Drug Administration; ACS; acute coronary syndrome; PCIs; percutaneous coronary interventions; PPIs; proton pump inhibitors; ACCF; American College of Cardiology Foundation; A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Prediction of Inter-individual Variability in the Pharmacokinetics of CYP2C19 Substrates in Humans

Keywords: CYP2C19; inter-individual variability; human pharmacokinetics; Monte Carlo simulation; pharmacogenetics; drug development

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Common variants in the CYP2C19 gene are associated with susceptibility to endometriosis

Keywords: Endometriosis; association; pooled sequencing; CYP2C19; rs12248560; rs4244285;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Personalized antiplatelet therapy according to CYP2C19 genotype after percutaneous coronary intervention: A randomized control trial

Keywords: Clopidogrel; Genetics; CYP2C19; Stent thrombosis; Personalized medicine;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The CYP2C19 genotype does not impact the long-term prognosis of patients with coronary artery disease

Keywords: CYP2C19; Polymorphism; Coronary artery disease; Prognosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Regular ArticleGenetic determinants of high on-treatment platelet reactivity in clopidogrel treated Chinese patients

Keywords: Clopidogrel; Pharmacogenetics; Platelet reactivity; CYP2C19; ABCB1; PON1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Predicting CYP2C19 catalytic parameters for enantioselective oxidations using artificial neural networks and a chirality code

Keywords: CYP2C19; cytochrome P450 2C19; MDMA; 3,4-methylenedioxy-N-methylamphetamine; MDEA; 3,4-methylenedioxy-N-ethylamphetamine; MBDB; N-methyl-1,3-benzodioxolylbutanamine; BDB; 3,4-methylenedioxy-α-ethylphenethylamine; ANN; artificial neural network; HPLC; hig

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Influence of genetic and non-genetic factors on the plasma concentrations of the clopidogrel metabolite (SR26334) among Chinese patients

Keywords: Genetic polymorphism; CYP2C19; Chinese; Clopidogrel metabolite (SR26334); Non-genetic factors

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

CYP3A4 and CYP2C19 genetic polymorphisms and zolpidem metabolism in the Chinese Han population: A pilot study

Keywords: CYP3A4; CYP2C19; Zolpidem metabolism

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

PON1 Q192R genotype influences clopidogrel responsiveness by relative platelet inhibition instead of on-treatment platelet reactivity

Keywords: clopidogrel; PON1; CYP2C19; platelet; responsiveness

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A poor metabolizer of both CYP2C19 and CYP2D6 identified by mechanistic pharmacokinetic simulation in a fatal drug poisoning case involving venlafaxine

Keywords: CYP2D6; CYP2C19; Venlafaxine; Poor metabolizer; Drug poisoning; Mechanistic pharmacokinetic simulation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibiteurs de la pompe à protons et clopidogrel (Plavix®) : une liaison dangereuse ?

Keywords: Clopidogrel; Thiénopyridines; Inhibiteurs de pompes à protons; Interactions médicamenteuses; CYP450; CYP2C19Clopidogrel; Thienopyridines; Proton pump inhibitors; Drug-drug interaction; CYP450; CYP2C19

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The Influence of Smoking Status on the Pharmacokinetics and Pharmacodynamics of Clopidogrel and Prasugrel : The PARADOX Study

Keywords: clopidogrel; CYP1A2; CYP2C19; pharmacodynamics; pharmacokinetics; platelet; prasugrel; smokingAM, active metabolite; AUC, area under the curve; CAD, coronary artery disease; CI, confidence interval; C-IPA, calculated inhibition of platelet aggregation; CY

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Patient Selection for Transcatheter Aortic Valve Replacement

Keywords: cardiac surgery; clopidogrel; CYP2C19; genetics; interventional cardiology; platelet function; prasugrel; ticagrelor; transcatheter aortic valve replacement;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: Effects on clopidogrel response

Keywords: Clopidogrel; CYP2C19; Gene polymorphisms; MDR1; P2Y12

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Platelet Function and Genetic Testing

Keywords: antiplatelet; clopidogrel; CYP2C19; genetics; platelet function; prasugrel; ticagrelor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Cytochrome CYP2C19 polymorphism and risk of adverse clinical events in clopidogrel-treated patients: A meta-analysis based on 23,035 subjects

Keywords: CYP2C19; Clopidogrel; Meta-analysis; Coronary artery diseaseClopidogrel; Méta-analyse; Maladie coronaireACS, Acute coronary syndrome; CAD, Coronary artery disease; CI, Confidence interval; CYP, Cytochrome P450; MI, Myocardial infarction; OR, Odds ratio; P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of rabeprazole on the antiplatelet effects and pharmacokinetics of clopidogrel in healthy volunteers

Keywords: Clopidogrel; CYP2C19 protein; Drug interactions; Proton-pump inhibitors; Vasodilator-stimulated phosphoproteinClopidogrel; CYP2C19; Interactions médicamenteuses; Inhibiteurs de pompes à protons; Protéine VASPADP, adenosine diphosphate; CYP, cytochrome P-4

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Monkey liver cytochrome P450 2C19 is involved in R- and S-warfarin 7-hydroxylation

Keywords: P450; general term for cytochrome P450 (EC 1.14.14.1); Cynomolgus monkey; Human; CYP2C19; CYP2C9; Stereoselectivity;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

CYP2C19*2 and other genetic variants affecting platelet response to clopidogrel in patients undergoing percutaneous coronary intervention

Keywords: Clopidogrel; Percutaneous coronary intervention; Platelet reactivity; CYP2C19; CYP2B6*5; P2RY12;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Correlation of CYP2B6, CYP2C19, ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients

Keywords: CYP2B6; CYP2C19; ABCC4; SOD2; Cyclophosphamide; Blood or marrow transplantation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism

Keywords: CPF, chlorpyrifos; CYP, cytochrome P450; OP, organophosphorus; CPF-O, chlorpyrifos oxon; TCPy, 3,5,6-trichloro-2-pyridinol; HLM, human liver microsome; AChE, acetylcholinesterase; BChE, butyrylcholinesteraseCYP2B6; CYP2C19; Chlorpyrifos; Biotransformation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Ability of Rabeprazole to Prevent Gastric Mucosal Damage From Clopidogrel and Low Doses of Aspirin Depends on CYP2C19 Genotype

Keywords: Stomach; PPI; Drug Interactions; Cardiovascular; AC; aspirin and clopidogrel; ARU; aspirin reaction unit; CYP2C19; S-mephenytoin 4′-hydroxylase; GSRS; Gastrointestinal Symptom Rating Scale; IM; intermediate metabolizer; IPA; inhibition of platelet aggre

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Influence of Genetic Polymorphisms on the Effect of High- and Standard-Dose Clopidogrel After Percutaneous Coronary Intervention : The GIFT (Genotype Information and Functional Testing) Study

Keywords: clopidogrel; CYP2C19; genotype; platelet function testing; thienipyridineACS, acute coronary syndrome(s); CI, confidence interval; CYP, cytochrome 450; MD, maintenance dose; OTR, on-treatment reactivity; PCI, percutaneous coronary artery; PRU, P2Y12 react

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: Relevance to cellular therapies

Keywords: AFP; alpha fetoprotein; Alb; albumin; ATP5g1; mitochondrial F0 complex, subunit C1 (subunit 9), ATP synthase 5 subunit e; ATP8; ATP synthase 8; BAL; bioartificial liver; BMP4; bone morphogenetic protein 4; CYP; cytochrome P450; CYP2C19; CYP Family 2, Subf

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of cytochrome P450 2D6 and 2C9 substrates and inhibitors by QSAR analysis

Keywords: CYP; cytochrome P450; CYP2C9; cytochrome P450 subtype 2C9; CYP2D6; cytochrome P450 subtype 2D6; CYP1A2; cytochrome P450 subtype 1A2; CYP2C19; cytochrome P450 subtype 2C19; CYP3A4; cytochrome P450 subtype 3A4; PLR; partial logistic regression; PLS; partial

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

High-density fine-mapping of a chromosome 10q26 linkage peak suggests association between endometriosis and variants close to CYP2C19

Keywords: Endometriosis; linkage; association; subfertility; CYP2C19

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of a CYP2C19 genotype panel on the GenMark eSensor® platform and the comparison to the Autogenomics Infiniti™ and Luminex CYP2C19 panels

Keywords: CYP2C19; cytochrome; P450 2C19; gene; ACS; acute cornoary syndrome; STEMI; ST-segment-elevation acute myocardial infarction; Cytochrome P450; CYP2C19; Clopidogrel; Pharmacogenomics;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Chiral assay of omeprazole and metabolites and its application to a pharmacokinetics related to CYP2C19 genotypes

Keywords: (R)-Omeprazole; (S)-Omeprazole; (R)-5-Hydroxyomeprazole; (S)-5-Hydroxyomeprazole; Omeprazole sulfone; CYP2C19

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes

Keywords: Cannabidiol; Metabolism; Human liver microsomes; Cytochrome P450; CYP3A4; CYP2C19

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19)

Keywords: Andrographis paniculata; Centella asiatica; Orthosiphon stamineus; CYP2C19; Drug-herb interactions;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Prasugrel Overcomes High On-Clopidogrel Platelet Reactivity Post-Stenting More Effectively Than High-Dose (150-mg) Clopidogrel : The Importance of CYP2C19*2 Genotyping

Keywords: CYP2C19; high-dose clopidogrel; pharmacogenetics; platelet reactivity; prasugrelCABG, coronary artery bypass grafting; CI, confidence intervals; CYP, cytochrome; HTPR, high on-treatment platelet reactivity; LS, least squares; PCI, percutaneous coronary in

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Esomeprazole With Clopidogrel Reduces Peptic Ulcer Recurrence, Compared With Clopidogrel Alone, in Patients With Atherosclerosis

Keywords: Proton-Pump Inhibitor; Plavix; CYP2C19; Drug Interactions; hetEM; heterogeneous extensive metabolizer; homEM; homogeneous extensive metabolizer; ITT; intention to treat; NSAID; nonsteroidal anti-inflammatory drug; PM; poor metabolizer; PPA; percentage of

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Pharmacogenomics of clopidogrel: Evidence and perspectives

Keywords: CYP; cytochrome P450; paraoxonase-1; PON1; PCI; percutaneous coronary intervention; ADP; adenosine diphosphate; cAMP; cyclic adenosine monophosphate; VASP; vasodilator-stimulated phosphoprotein; OR; odds ratio; CI; confidence interval; PPI; proton-pump in

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation

Keywords: ACN; acetonitrile; APAP; acetaminophen; CYP1A2; cytochrome P450 1A2 enzyme; CYP2B6; cytochrome P450 2B6 enzyme; CYP2C19; cytochrome P450 2C19 enzyme; CYP2D6; cytochrome P450 2D6 enzyme; CYP3A4; cytochrome P450 3A4 enzyme; CYP450; cytochrome P450 enzymes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of comedication with proton pump inhibitors (PPIs) on post-interventional residual platelet aggregation in patients undergoing coronary stenting treated by dual antiplatelet therapy

Keywords: Clopidogrel; Proton pump inhibitors; CYP2C19; Platelet aggregation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Pharmacogenetic biomarkers as tools for improved drug therapy; emphasis on the cytochrome P450 system

Keywords: Adverse drug reactions; Drug metabolism; Clopidogrel; CYP2C19; CYP2D6

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

CYP17 and CYP2C19 gene polymorphisms in patients with endometriosis

Keywords: CYP2C19; CYP17; cytochrome P450; endometriosis; gene polymorphism

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Understanding Clopidogrel's Interaction with CYP2C19 Inhibitors

Keywords: acute coronary syndrome; angioplasty; clopidogrel; CYP2C19; drug interactions; FDA warning

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Investigation of allele and genotype frequencies of CYP2C9, CYP2C19 and VKORC1 in Iran

Keywords: CYP2C9; CYP2C19; VKORC1; Iranian; genotype

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Pilot Study of the Antiplatelet Effect of Increased Clopidogrel Maintenance Dosing and Its Relationship to CYP2C19 Genotype in Patients With High On-Treatment Reactivity

Keywords: clopidogrel; CYP2C19; platelet; thienopyridineADP, adenosine diphosphate; BMI, body mass index; CAD, coronary artery disease; DNA, deoxyribonucleic acid; LoF, loss-of-function; OTR, on-treatment reactivity; PCI, percutaneous coronary intervention; PPI, pr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression

Keywords: CYP2C19; GATA; FOG-2; Promoter-mediated regulation; Drug metabolism; Omeprazole; Escitalopram

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Impact of Cytochrome P450 2C19 Loss-of-Function Polymorphism and of Major Demographic Characteristics on Residual Platelet Function After Loading and Maintenance Treatment With Clopidogrel in Patients Undergoing Elective Coronary Stent Placement

Keywords: antiplatelet therapy; CYP2C19; platelet function; polymorphism; predictorADP, adenosine diphosphate; BMI, body mass index; CART, classification and regression trees; CYP, cytochrome P450; DNA, deoxyribonucleic acid; MI, myocardial infarction; PCI, percuta

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه