دانلود مقالات ISI درباره Cyp7A1 + ترجمه فارسی

Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists

Keywords: FXR; farnesoid X receptor; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; SHP; small heterodimer partner; RXRα; retinoid X receptor α; 9-cis-RA; 9-cis-retinoic acid; LBD; ligand binding domain; TR-FRET; time-resolved fluorescence reso

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation

Keywords: SREBP; sterol regulator element-binding protein; HMGCR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; CYP7A1; cholesterol-7alpha-hydroxylase; CYP27A1; cholesterol-27alpha-hydroxylase; ACAT1; acetyl-CoA cholesterol acyltransferase 1; LDLR; low density l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Cassia auriculata flower extract attenuates hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol metabolism

Keywords: Et- CAF; ethanolic extract of Cassia auriculata flower; HMGR; HMG-CoA reductase; HMGS; HMGCoA synthase; SREBP-1c; sterol regulatory element binding protein -1c; SREBP-2; sterol regulatory element binding protein- 2; CYP7A1; cholesterol 7 α-hydroxylase; A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

16-Dehydropregnenolone lowers serum cholesterol by up-regulation of CYP7A1 in hyperlipidemic male hamsters

Keywords: 16-Dehydropregnenolone; Cholesterol; Bile acid; CYP7A1; LXRα; PPARα; HepG2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Bile acid profiles in neonatal intrahepatic cholestasis caused by citrin deficiency

Keywords: NICCD; neonatal intrahepatic cholestasis caused by citrin deficiency; CYP7A1; cholesterol 7α-hydroxylase; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; LCA; lithocholic acid; ROC; receiver operating characteristic; AGC; aspartate-g

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

7S protein is more effective than total soybean protein isolate in reducing plasma cholesterol

Keywords: Cholesterol; β-conglycinin; CYP7A1; 7S protein; Soy protein isolate; Sterols;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Red paprika (Capsicum annuum L.) and its main carotenoid capsanthin ameliorate impaired lipid metabolism in the liver and adipose tissue of high-fat diet-induced obese mice

Keywords: NAFLD; non-alcoholic fatty liver disease; WAT; white adipose tissue; ND; normal diet; HD; high-fat diet; RP; red paprika-supplemented diet; CS; capsanthin-supplemented diet; TG; triacylglycerol; TC; total cholesterol; HDL; high-density lipoprotein; NEFA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression

Keywords: FGF; fibroblast growth factor; PXR; pregnane X receptor; NR; nuclear receptor; CAR; constitutive androstane receptor; CYP; cytochrome P450; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; HFD; high fat diet; KO; knockout; ob; obesity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression

Keywords: SCH; subclinical hypothyroidism; TC; total cholesterol; LDL-c; low-density lipoprotein cholesterol; TSH; thyroid stimulating hormone; TSHR; thyroid stimulating hormone receptor; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PCSK9; proprotein convertase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver

Keywords: ASBT; apical sodium-dependent bile salt transporter; BSEP; bile salt export pump; COX2; cyclooxygenase 2; CYP7A1; cholesterol 7α-hydroxylase; FXR; farnesoid X receptor; HFHC; high fat and high cholesterol; HMGCR; 3-hydroxy-3-methyl glutaryl coenzyme A re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Mouse species-specific control of hepatocarcinogenesis and metabolism by FGF19/FGF15

Keywords: FGF19; FGF15; Carcinoma, hepatocellular; Bile acids and salts; Glucose; Body weight; Cyp7a1; Obesity; Diet; Receptors, cytoplasmic and nuclear; Metabolic diseases;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner

Keywords: ALD; alcoholic liver disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BSEP; bile salt export pump; CPT1; carnitine palmitoyltransferase I; CYP7A1; cholesterol 7-alpha hydroxy-lase; DHA; dihydroartemisinin

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock

Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1-AKT-mTOR Axis in Mice

Keywords: Cholesterol; Cholestyramine; Fatty Liver; Nuclear Receptor; ACAT; acyl-CoA:cholesterol acyltransferase; CE; cholesterol ester; ChTM; cholestyramine; CQ; chloroquine; CYP7A1; cholesterol 7α-hydroxylase; DIO; diet-induced obesity; ER; endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

The interrelationship between bile acid and vitamin A homeostasis

Keywords: ATGL; Adipose triglyceride lipase; ADH; Alcohol dehydrogenase; ALD; Alcoholic liver disease; atRA; All-trans retinoic acid; ASBT/SLC10A2; Apical sodium-dependent bile salt transporter; ABCA1; ATP-binding cassette transporter member 1; BCMO1; Beta-carotene

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Diet-induced obesity and weight loss alter bile acid concentrations and bile acid-sensitive gene expression in insulin target tissues of C57BL/6J mice

Keywords: Bile acids; Obesity; Weight loss; Gene expression; Mice; Abcc3; ATP binding cassette subfamily C member 3; Acox2; peroxisomal branched chain acyl-CoA oxidase; Amacr; α-methylacyl-CoA racemase; ANOVA; analysis of variance; BA; bile acids; Bal; bile acid C

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α

Keywords: CDCA; chenodeoxycholic acid; ChIP; chromatin immunoprecipitation assays; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7α-hydroxylase; DMEM; Dulbecco's Modified Eagle Medium/High glucose; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; FXR; far

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice

Keywords: STAT5; signal transducer and activator of transcription 5; GH; growth hormone; IGF-1; insulin-like growth factor-1; LDLR; low-density lipoprotein receptor; STAT5 LKO; liver-specific STAT5 knock-out; STAT5 fl/fl; STAT5 flox/flox; TG; triacylglycerol; ChMCs

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Eating for two: Consequences of parental methionine nutrition on offspring metabolism in rainbow trout (Oncorhynchus mykiss)

Keywords: abca1; ATP-binding cassette transporter A1;; abcg5; ATP-binding cassette sub-family G member 5; abcg8; ATP-binding cassette sub-family G member 8; acly; ATP citrate lyase; atg4b; autophagy related 4B; atg12l; autophagy related 12-like; atp6v1a; ATPase, HÂ

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison of simple extraction procedures in liquid chromatography⿿mass spectrometry based determination of serum 7α-hydroxy-4-cholesten-3-one, a surrogate marker of bile acid synthesis

Keywords: au; arbitrary units; BA; bile acid(s); C4; 7α-hydroxy-4-cholesten-3-one; CYP7A1; cholesterol 7α-hydroxylase; IS; internal standard; LC⿿MS; liquid chromatography⿿mass spectrometry; MS; mass spectrometry; 7α-Hydroxy-4-cholesten-3-one; Bile acids; Cho

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of 7α-OH cholesterol by LC–MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs

Keywords: FXR, Farnesoid X receptor; CDCA, Chenodeoxycholic acid; OCA, Obeticholic acid; TPN, Total Parenteral Nutrition; DTT, dithiothreitol; PMSF, phenylmethanesulfonyl fluorideLC–MS/MS; CYP7A1; Cholesterol 7α-hydroxylase activity; 7α-OH cholesterol; Liver micros

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Pleiotropic effects of antitumour alkylphospholipids on cholesterol transport and metabolism

Keywords: ABCA1; ATP-binding cassette transporter isoform A1; APL; alkylphospholipid; apoA1; apolipoprotein A1; CETP; cholesteryl ester transfer protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27; sterol 27-hydroxylase; DHCR7; 7-dehydrocholesterol reductase; ER; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters

Keywords: Rhizoma Coptidis; Synergetic effect; Hypercholesterolemia; LDL receptor; HMGCR; CYP7A1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Crabapple fruit extracts lower hypercholesterolaemia in high-fat diet-induced obese mice

Keywords: Crabapple; Hyperlipidaemia; Hypercholesterolaemia; Metabolic syndrome; Anti-oxidation; CYP7A1; Procyanidin (PubChem CID: 107876); Epicatechin (PubChem CID: 72276); Isoastilbin (PubChem CID: 10114809); Quercetin 3-O-glucoside (PubChem CID: 44258003); Avicu

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Hypocholesterolemic effect of emodin by simultaneous determination of in vitro and in vivo bile salts binding

Keywords: Hypercholesterolemia; Total cholesterol; Bile acids; CYP7A1; Signaling pathway;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease

Keywords: Bile Acids; Farnesoid X Receptor; Metabolic Disease; Ceramides; BSH; bile salt hydrolase; CA; cholic acid; cAMP; cyclic adenosine monophosphate; CDCA; chenodeoxycholic acid; CYP; cytochrome P450s; CYP7A1; CYP with cholesterol 7α-hydroxylase; DCA; deoxych

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

HDL functionality in reverse cholesterol transport - Challenges in translating data emerging from mouse models to human disease

Keywords: ABC; ATP-binding cassette transporter; Apo; apolipoprotein; apobec1; apoB mRNA editing enzyme; ASBT; apical sodium-dependent bile acid transporter; BA; bile acids; BAT; bile acid CoA:amino acid N-acyltransferase; BSEP; bile salt export pump; CEC; choleste

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters

Keywords: OV; Opisthorchis viverrini; CCA; cholangiocarcinoma; NEC; nanoencapsulated curcumin; PZQ; praziquantel; PDF; periductal fibrosis; BC; bile canaliculi; Cur; curcumin; ALT; alanine transaminase; MMP; matrix metalloproteinases; TIMP; tissue inhibitors of MMP

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2016 سفارش ترجمه

Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion

Keywords: Cyp7a1; Abcg5; Abcg8; Dietary sucrose; Cholesterol; Bile acid synthesis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A global transcriptional analysis of Megalobrama amblycephala revealing the molecular determinants of diet-induced hepatic steatosis

Keywords: Acads; acyl-CoA dehydrogenase; ALT; alanine aminotransferase; apoa1; apolipoprotein a1; Bdh1; 3-hydroxybutyrate dehydrogenase; COG; Cluster of Orthologous Groups; Cyp7a1; cytochrome p450 7a1; DGE; digital gene expression; Dhcr7; 7-dehydrocholesterol reduc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Mesenchymal stem cells: In vivo therapeutic application ameliorates carbon tetrachloride induced liver fibrosis in rats

Keywords: ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate transaminase; BM; bone marrow; Bsep; bile salt export pump; CCl4; carbon tetrachloride; CYP27A1; Mitochondrial sterol 27-hydroxylase; CYP7A1; microsomal cholesterol 7α-hydroxylase; DMEM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease

Keywords: FXR; farnesoid X receptor; ALD; alcoholic liver disease; SHP; small heterodimer partner; BSEP; bile salt export pump; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; CYP2E1; c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of nuclear receptor NR5A2 increases Glut4 expression and glucose metabolism in muscle cells

Keywords: NR5A2; nuclear receptor subfamily 5, group A, member; GLUT4; glucose transporter 4; Acc2; acetyl-CoA carboxylase 2; DLPC; dilauroyl phosphatidylcholine; CEPT; Cholesteryl ester transfer protein; CYP7A1; cholesterol 7 alpha-hydroxylase; CYP8B1; sterol 12-a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Partial cloning, tissue distribution and effects of epigallocatechin gallate on hepatic 3-hydroxy-3-methylglutaryl-CoA reductase mRNA transcripts in goldfish (Carassius auratus)

Keywords: ABCA1; ATP-binding cassette transporter A1; BW; body weight; CYP7A1; cholesterol 7alpha-hydroxylase; EGCG; Epigallocatechin gallate; HMGCoAR; 3-hydroxy-3-methylglutaryl-CoA reductase; HMGCoAR-a; 3-hydroxy-3-methylglutaryl-CoA reductase isoform A; HMGCoAR-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol-lowering effect of Lactobacillus plantarum NCU116 in a hyperlipidaemic rat model

Keywords: CVDs; cardiovascular diseases; CYP7A1; cholesterol 7α-hydroxylase; HDL-C; high-density lipoprotein cholesterol; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; LDL-C; low-density lipoprotein cholesterol; SREBP-2; sterol regulatory element-binding protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Chrysanthemum morifolium extract attenuates high-fat milk-induced fatty liver through peroxisome proliferator-activated receptor α-mediated mechanism in mice

Keywords: CME; Chrysanthemum morifolium extract; CYP7A1; cholesterol 7α-hydroxylase 1; DGAT; diacylglycerol acyltransferase; FAS; fatty acid synthase; FFA; free fatty acid; LPL; lipoprotein lipase; PPARα; peroxisome proliferator-activated receptor α; RT-PCR; rev

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Ezetimibe enhances macrophage reverse cholesterol transport in hamsters: Contribution of hepato-biliary pathway

Keywords: RCT; reverse cholesterol transport; CETP; cholesterol ester transfer protein; BDL; bile duct ligation; TICE; transintestinal cholesterol efflux; LDLR; low-density lipoprotein receptor; ABCA1; ATP-binding cassette transporter A; NPC1L1; Niemann-Pick C1-l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis

Keywords: Rhizoma Coptidis; Jatrorrhizine; Antihypercholesterolemia; LDLR; CYP7A1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleAltered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease

Keywords: SBS; short bowel syndrome; SBS-ALD; short bowel syndrome-associated liver disease; PN; parenteral nutrition; SBR; small bowel resection; BA; bile acid; FXR; farnesoid X receptor; SHP; small heterodimer partner; FGF19; fibroblast growth factor 19; CYP7A1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The role of common variants of ABCB1 and CYP7A1 genes in serum lipid levels and lipid-lowering efficacy of statin treatment: A meta-analysis

Keywords: Single-nucleotide polymorphisms; Serum lipid level; ABCB1; CYP7A1; Statin; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol reducing and bile-acid binding properties of taioba (Xanthosoma sagittifolium) leaf in rats fed a high-fat diet

Keywords: BA; bile acid; CEL; cellulose; CNCD; chronic non-communicable diseases; CYP7A1; cholesterol 7α-hydroxylase; FER; feed efficiency ratio; FFM; fat-free mass; INU; inulin; LCEL; low cellulose; LTL; lyophilised taioba leaf; RAF; relative abdominal fat; SCFA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2

Keywords: Epigallocatechin gallate; Bile formation; Cholestasis; Bile acids; Asbt; apical sodium-dependent bile salt transporter; ALT; alanine transaminase; AST; aspartate transaminase; Bsep; bile salt exporting pump; CDCA; chenodeoxycholic acid; Cyp7a1; cholestero

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Pectin pentasaccharide from hawthorn (Crataegus pinnatifida Bunge. Var. major) ameliorates disorders of cholesterol metabolism in high-fat diet fed mice

Keywords: HMGCR; 3-hydroxy-3-methyl-glutaryl-CoA reductase; SREBP-2; sterol regulatory element-binding protein 2; LDLR; low density lipoprotein receptor; CYP7A1; cholesterol 7α-hydroxylase; ACAT; acyl-coenzyme A: cholesterol acyl-transferase; Actb; actin beta; HPP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters

Keywords: apo-A1; apolipoprotein-A1; bw; body weight; CAT; catalase; CDNB; 1-chloro-2,4-dinitrobenzene; CPT-1; carnitine palmitoyltransferase-1; CYP7A1; cytochrome P450 7A1; DTNB; 5,5-dithiobis[2-nitrobenzoic acid]; EDTA; ethylenediaminetetraacetic acid; FXR; farne

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis

Keywords: α-Sma; smooth muscle-α-actin; BHLHB2; basic helix-loop-helix domain containing class B2; COL1A1; collagen, type I, alpha 1; COL1A2; collagen, type I, alpha 2; CYP7A1; cytochrome P450 Family 7 Subfamily A Polypeptide 1; DMEM; Dulbecco's modified eagleâ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Postprandial response and tissue distribution of the bile acid synthesis-related genes, cyp7a1, cyp8b1 and shp, in rainbow trout Oncorhynchus mykiss

Keywords: cyp7a1; cyp8b1; shp; Bile acid; Tissue distribution; Postprandial response; Fish;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis

Keywords: StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes

Keywords: CBS; C/EBPα binding site; C/EBPs; CCAAT/enhancer binding proteins; ChIP; chromatin immunoprecipitation assay; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7α-hydroxylase; FAS; fatty acid synthase; HDAC; histone deacetylase; HFD-MetS; high-fat-diet

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

An efficient synthesis of 7α,12α-dihydroxy-4-cholesten-3-one and its biological precursor 7α-hydroxy-4-cholesten-3-one: Key intermediates in bile acid biosynthesis

Keywords: CYP7A1; cholesterol 7α-hydroxylase; HSD3B7; 3β-hydroxy-Δ5-C27-steroid oxidoreductase; TEMPO; 2,2,6,6-tetramethylpiperidine 1-oxyl free radical; IBX; 2-iodoxybenzoic acid; Bile acid biosynthesis; 7α-Hydroxy-4-cholesten-3-one; 7α,12α-Dihydroxy-4-chole

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه