Keywords: Resistin-like molecule; Macrophage; Helminth infection; T helper type 2; Toll-like Receptor 4; ABC; ATP-binding cassette transporter; ADD1; adipocyte determination and differentiation dependent factor 1; ADSF; adipocyte secreted factor; Akt (aka PKB); pro
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Keywords: Bile Acids; FXR; TGR5; Meta-Inflammation; apo; apolipoprotein; ASBT; apical sodiumâdependent bile acid transporter; BA; bile acid; BAS; bile acid sequestrant; BAT; brown adipose tissue; BSH; bile salt hydrolase; CA; cholic acid; CCK; cholecystokinin; CD
Keywords: ASBT; apical sodium dependent transporter; AKT; protein kinase B; BSEP; bile salt export protein (ABCB11); CA; cholic acid; CCA; cholangiocarcinoma; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; CYP7B1; oxysterol 7α-hydroxylase; CYP27
The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17α-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats
Keywords: Asbt; apical sodium-dependent bile acids transporter; ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate transaminase; BAs; bile acids; Bsep/BSEP; bile salt export pump; β-MCA; β-muricholic acid; CA; cholic acid; CDCA; chenodeoxycholic
Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice
Keywords: Aryl hydrocarbon receptor; TCDD; Bile acids; Biliary excretion; Taurodeoxycholic acid; Cyp8b1; 1°BAs; Primary bile acids; 2°BAs; Secondary bile acids; 6-OH; 6-hydroxylated (6-OH); 12-OH; 12α-hydroxylated; Abc; ATP-binding cassette; AhR; Aryl hydrocarbo
Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand
Keywords: CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; LCA; litocholic acid; BAs; bile acids; BARS; bile acid activated receptors; GPBAR1; G protein coupled bile acid receptor; TGR5; Takeda G protein receptor 5; FXR; farnesoid x-receptor; PX
Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression
Keywords: FGF; fibroblast growth factor; PXR; pregnane X receptor; NR; nuclear receptor; CAR; constitutive androstane receptor; CYP; cytochrome P450; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; HFD; high fat diet; KO; knockout; ob; obesity
Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression
Keywords: SCH; subclinical hypothyroidism; TC; total cholesterol; LDL-c; low-density lipoprotein cholesterol; TSH; thyroid stimulating hormone; TSHR; thyroid stimulating hormone receptor; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PCSK9; proprotein convertase
The interrelationship between bile acid and vitamin A homeostasis
Keywords: ATGL; Adipose triglyceride lipase; ADH; Alcohol dehydrogenase; ALD; Alcoholic liver disease; atRA; All-trans retinoic acid; ASBT/SLC10A2; Apical sodium-dependent bile salt transporter; ABCA1; ATP-binding cassette transporter member 1; BCMO1; Beta-carotene
Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice
Keywords: STAT5; signal transducer and activator of transcription 5; GH; growth hormone; IGF-1; insulin-like growth factor-1; LDLR; low-density lipoprotein receptor; STAT5 LKO; liver-specific STAT5 knock-out; STAT5 fl/fl; STAT5 flox/flox; TG; triacylglycerol; ChMCs
Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease
Keywords: FXR; farnesoid X receptor; ALD; alcoholic liver disease; SHP; small heterodimer partner; BSEP; bile salt export pump; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; CYP2E1; c
Activation of nuclear receptor NR5A2 increases Glut4 expression and glucose metabolism in muscle cells
Keywords: NR5A2; nuclear receptor subfamily 5, group A, member; GLUT4; glucose transporter 4; Acc2; acetyl-CoA carboxylase 2; DLPC; dilauroyl phosphatidylcholine; CEPT; Cholesteryl ester transfer protein; CYP7A1; cholesterol 7 alpha-hydroxylase; CYP8B1; sterol 12-a
Combining metabolomic analysis and microarray gene expression analysis in the characterization of the medicinal plant Chelidonium majus L
Keywords: Chelidonii herba; Herbal safety; Gene expression profiling; 1H-NMR fingerprint; IPA; Ingenuity pathway analysis; PCA; Principal component analysis; qRT-PCR; quantitative real-time PCR; AhRR; Aryl-hydrocarbon receptor repressor; AKR1B10; Aldo-keto reductas
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
Postprandial response and tissue distribution of the bile acid synthesis-related genes, cyp7a1, cyp8b1 and shp, in rainbow trout Oncorhynchus mykiss
Keywords: cyp7a1; cyp8b1; shp; Bile acid; Tissue distribution; Postprandial response; Fish;
Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis
Keywords: StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac
Glucocorticoids Promote Hepatic Cholestasis in Mice by Inhibiting the Transcriptional Activity of the Farnesoid X Receptor
Keywords: Bile Acid Metabolism; Small Heterodimer Partners; Liver Disease; Nuclear Receptor; ALT; alanine aminotransferase; BA; bile acid; BMI; body mass index; ChIP; chromatin immunoprecipitation; CtBP; C-terminal binding protein; Cyp7A1; cytochrome P450, family 7
Lack of adiponectin promotes formation of cholesterol gallstones in mice
Keywords: Gallstone; Adiponectin; cyp8b1; apoA-I; Phospholipase A2; ppar-α
Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis
Keywords: FXR; farnesoid X receptor; SHP; small heterodimer partner; BSEP; bile salt export pump; MCD; methionine- and choline-deficient; NASH; nonalcholic steatohepatitis; NAFLD; non-alcoholic fatty liver disease; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; stero
Feedback regulation of bile acid synthesis in human liver: Importance of HNF-4α for regulation of CYP7A1
Keywords: Bile acid synthesis; Cholestyramine; Chenodeoxycholic acid; CYP7A1; CYP8B1; HNF-4α; Nuclear factors;
The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors
Keywords: ASBT; apical sodium-dependent bile acid transporter; I-BABP; ileal bile acid-binding protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27A1; sterol 27-hydroxylase; CYP8B1; sterol 12α-hydroxylase; PPAR; peroxisome proliferator-activated receptors; RXR; ret