Discovery and characterization of N-(1,3-dialkyl-1H-indazol-6-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine scaffold as mGlu4 positive allosteric modulators that mitigate CYP1A2 induction liability
Keywords: mGlu4 PAM; Positive allosteric modulator; CYP induction; Parkinson's disease; Structure-activity relationship;