Keywords: دی هیدروفلات ردوکتاز; ALL; acute lymphoblastic leukemia; AraC; cytosine Arabinoside; BrdU; bromodeoxyuridine; CNS; central nervous system; DG; Dorsal Ganglion; DHFR; dihydrofolate reductase; IP; intraperitoneal; LSD; Fisher's least significant difference; MTX; methotrexate;
مقالات ISI دی هیدروفلات ردوکتاز (ترجمه نشده)
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Keywords: دی هیدروفلات ردوکتاز; Flavoenzymes; Folate; Mutagenesis; Enzyme kinetics; Reductase; Glutamine; CH2-H4folate; 5,10-methylenetetrahydrofolate; CH3-H4folate; 5-methyltetrahydrofolate; DHFR; dihydrofolate reductase; E. coli; Escherichia coli; EDTA; ethylenediaminetetraacetic acid
Keywords: دی هیدروفلات ردوکتاز; 5-FU; 5-Fluorouracil; AI; aromatase inhibitor; BC; breast cancer; CDK; cyclin-dependent kinase; DHF; dihydrofolate; DHFR; dihydrofolate reductase; ER; estrogen receptor; FSH; follicle stimulating hormone; FDA; Food & Drug Administration; GnRH; gonadotroph
Keywords: دی هیدروفلات ردوکتاز; Colorectal cancer; Methotrexate; Therapy-induced senescence; Dihydrofolate reductase; Nitric oxide signaling;
Keywords: دی هیدروفلات ردوکتاز; Folic acid; Folate; Fortification; Supplementation; Neural tube defect; Primary prevention; ASD; autism spectum disorder; BfR; Bundesinstitut für Risikobewertung, Federal Republic of Germany; Cbl; cyanocobalamin; CDC; Centers for Disease Control and Prev
Keywords: دی هیدروفلات ردوکتاز; Schistosoma mansoni; Nucleotide metabolism; Dihydrofolate reductase (DHFR); Isothermal titration calorimetry (ITC); X-ray crystallography; DHFR; dihydrofolate reductase; rSmDHFR; recombinant Schistosoma mansoni DHFR; NADPH and NADP+; nicotinamide adenine
Keywords: دی هیدروفلات ردوکتاز; Folate pathway; Trypanosomatids; Structure-based drug design; Selective inhibition; Enzyme inhibitor; Anti-parasitic drug; PTR1; Pteridine reductase 1; DHFR; Dihydrofolate reductase; dUMP; Deoxyuridine monophosphate; dTMP; Deoxythymidine monophosphate; hD
Keywords: دی هیدروفلات ردوکتاز; Quinoline; Tetrazole; Regioisomer; Molecular docking; DNA; N-Myristoyl transferase; Dihydrofolate reductase; Anticancer activity; Antifungal screening;
Keywords: دی هیدروفلات ردوکتاز; Dihydrofolate Reductase; DHFR; Structure-based Alignment; Phylogeny; Evolution; Plasmid evolution; Horizontal Gene Transfer; Network of Coupled Protein Motion;
Keywords: دی هیدروفلات ردوکتاز; Extremely randomized trees; Decision trees; Structure-activity relationship; Molecular modeling; Antimalarials; Dihydrofolate reductase; Trimethoprim; Pyrimethamine; Cycloguanil; Hydrophobic feature;
Keywords: دی هیدروفلات ردوکتاز; CH2THF; 5,10-methylene tetrahydrofolate; DCD; dCTP deaminase; DCD-DUT; bifunctional dCTP deaminase-dUTPase; DUT; dUTPase; DHF; dihydrofolate; DHFR; dihydrofolate reductase; DHFR-TS; bifunctional dihydrofolate reductase - thymidylate synthase; FAD; f
Keywords: دی هیدروفلات ردوکتاز; Dihydrofolate reductase; Brugia malayi; Filariasis; Antifolate inhibitors; Steady-state kinetics
Keywords: دی هیدروفلات ردوکتاز; Bone morphogenetic protein-7 (BMP-7); Chinese hamster ovary (CHO) cells; Recombinant protein expression; Stable cell line; Bioreactor process; BMP-7; bone morphogenetic protein-7; CHO; Chinese hamster ovary; DHFR; dihydrofolate reductase; EC50; effective
Keywords: دی هیدروفلات ردوکتاز; Trimethoprim; Dihydrofolate reductase; Antibacterial; Hydrophobicity; Docking;
Keywords: دی هیدروفلات ردوکتاز; DHFR; dihydrofolate reductase; ecDHFR; Escherichia coli DHFR; NADPH; reduced nicotinamide adenine dinucleotide phosphate; NADP+; oxidized nicotinamide adenine dinucleotide phosphate; DHF; 7,8-dihydrofolate; THF; 5,6,7,8-tetrahydrofolate; Tris; tris(hydrox
Keywords: دی هیدروفلات ردوکتاز; 2Nal; 3-(2-naphthy)-alanine; AFWK; pheylalanine/tryptophan/lysine triple auxotrophic E. coli; DHB; 2,5-dihydroxybenzoic acid; DHF; dihydrofolate; DHFR; dihydrofolate reductase; Glu; glutamic acid; LB; Lria-Broth; Lys; lysine; MALDI-TOF MS; matrix-assisted
Keywords: دی هیدروفلات ردوکتاز; Indole; Anti-cancer activity; Dihydrofolate reductase;
Keywords: دی هیدروفلات ردوکتاز; Dihydrofolate reductase; Thioredoxin reductase; Dihydrotriazines; Chalcones; Antiproliferative activity;
Keywords: دی هیدروفلات ردوکتاز; Hybrid molecules; Anti-fungal; Anti-tubercular; Anti-malarial; anti-inflammatory; ACTs; artemesinin based combination therapy; CQ; chloroquine; CC50; concentration required to reduce growth by 50%; EC50; half maximal effective concentration; Fqa; ferroqui
Keywords: دی هیدروفلات ردوکتاز; Quartz crystal microbalance; Microscale thermophoresis; Protein complex; Thymidylate synthase; Dihydrofolate reductase; Thymidylate biosynthesis;
Keywords: دی هیدروفلات ردوکتاز; AS + SP; artesunate + sulfadoxine-pyrimethamine; P. falciparum; Plasmodium falciparum; CQ; chloroquine; dhfr; dihydrofolate reductase; dhps; dihydropteroate synthetase; crt; chloroquine resistance transporter; mdr-1; multi drug resistance 1; SNPs; s
Keywords: دی هیدروفلات ردوکتاز; Streptococcus mutans; Biofilm; Dihydrofolate reductase; Trimetrexate analogues;
Keywords: دی هیدروفلات ردوکتاز; Methotrexate; Pralatrexate; Dihydrofolate reductase; Folate; Folic acid; Purine synthesis; S phase; Apoptosis;
Keywords: دی هیدروفلات ردوکتاز; ADP; adenosine diphosphate; APH; aminoglycoside phosphotransferase (3â²)-IIIa; BSA; bovine serum albumin; Cc; iso-1-ferricytochrome c; CcP; ferricytochrome c peroxidase; CD; circular dichroism; ConA; concanavalin A; ÎCp; change in heat capacity; ÎG; Gi
Keywords: دی هیدروفلات ردوکتاز; sGC stimulator BAY 41-8543 (PubChem CID: 9953906); nitroglycerin (PubChem CID: 4510); nitric oxide (PubChem CID: 145068); peroxynitrite (PubChem CID: 104806); superoxide (PubChem CID: 5359597); 3-nitrotyrosine (PubChem CID: 65124); dihydroethidium (PubChe
Keywords: دی هیدروفلات ردوکتاز; Trypanosoma cruzi; Leishmania mexicana; Plasmodium berghei; Quinazoline; Dihydrofolate reductase; Pteridin reductase;
Keywords: دی هیدروفلات ردوکتاز; Immobilization; Activity assay; Radiolabeled inhibitor; Dihydrofolate reductase;
Keywords: دی هیدروفلات ردوکتاز; Bacterial surrogate; Dihydrofolate reductase; Dihydropteroate synthase; Plasmodium falciparum; Antimalarial; Synergism;
Keywords: دی هیدروفلات ردوکتاز; ACSS; acetyl-CoA synthetase; ADI; arginine deiminase; AML; acute myeloid leukaemia; AMPK; AMP-activated protein kinase; ALL; acute lymphoblastic leukaemia; ASS; argininosuccinate synthase; BCAAs; branched-chain amino acids; BPTES; bis-2-(5-phenylacetamido
Keywords: دی هیدروفلات ردوکتاز; Thymidylate synthase; Cryptosporidium; Inhibitor; Dihydrofolate reductase; Crystal structure;
Keywords: دی هیدروفلات ردوکتاز; Virtual screening; Thymidylate synthase; Dihydrofolate reductase; Toxoplasma gondii;
Keywords: دی هیدروفلات ردوکتاز; Folate intake; Requirements; Pregnancy; DFEs; dietary folate equivalents; DHFR; dihydrofolate reductase; DRI; Dietary Reference Intake; EAR; Estimated Average Requirements; FA; folic acid; MCV; mean corpuscular volume (MCV); MTHFR; methylenetetrahydrofola
Keywords: دی هیدروفلات ردوکتاز; amino-BH4; 4-amino-(6R)-5,6,7,8-tetrahydro-l-biopterin; BAECs; bovine aortic endothelial cells; BH2; 7,8-dihydro-l-biopterin; BH4; (6R)-5,6,7,8-tetrahydro-l-biopterin; cGMP; 3â²,5â²-cyclic guanosine monophosphate; DAHP; 2,4-diamino-6-hydroxypyrimidine;
Keywords: دی هیدروفلات ردوکتاز; Indole; Pyrazole; Anti-cancer activity; Dihydrofolate reductase; Interactions;
Keywords: دی هیدروفلات ردوکتاز; Antibiotic resistance; Bacillus anthracis; Dihydrofolate reductase; Dihydrophthalazine; Enantiomer; Racemate;
Keywords: دی هیدروفلات ردوکتاز; Ala; alanine; Amm; ammonium; ATP; adenosine triphosphate; CHO; Chinese hamster ovary cell; DHFR; dihydrofolate reductase; EFM; elementary flux mode; EP; extreme pathway; ETC; electron transfer chain; Glc; glucose; Gln; glutamine; Glu; glutamate; GLY; glyc
Keywords: دی هیدروفلات ردوکتاز; Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
Keywords: دی هیدروفلات ردوکتاز; ADA-SCID; adenosine deaminase deficiency; cDNA; complementary DNA; CHMP; Committee on Human Medicinal Products; DHFR; dihydrofolate reductase; DNA; deoxyribonucleic acid; E1; adenoviral gene; E1B 55K; adenoviral gene; EMA; European Medicines Agency; FDA;
Plasmodium RON12 localizes to the rhoptry body in sporozoites
Keywords: دی هیدروفلات ردوکتاز; RON; rhoptry neck protein; PV; parasitophorous vacuole; AMA1; apical membrane antigen 1; DHFR; dihydrofolate reductase; IFA; indirect immunofluorescence assay; IEM; immunoelectron microscopy; Merozoite; Plasmodium; Rhoptry; Rodent malaria; RON12; Sporozoi
The application of the HyPer fluorescent sensor in the real-time detection of H2O2 in Babesia bovis merozoites in vitro
Keywords: دی هیدروفلات ردوکتاز; DHFR; dihydrofolate reductase; GFP; green fluorescent protein; IRBC; infected red blood cell; PCR; polymerase chain reaction; RBC; red blood cell; TPx-1; thioredoxin peroxidase-1; Babesia; Reactive oxygen species; HyPer; Time-lapse imaging;
The folA gene from the Rickettsia endosymbiont of Ixodes pacificus encodes a functional dihydrofolate reductase enzyme
Keywords: دی هیدروفلات ردوکتاز; Rickettsia species phylotype G021; Ixodes pacificus; Dihydrofolate reductase; Recombinant protein; In vitro enzymatic assay;
Single-step purification of recombinant Gaussia luciferase from serum-containing culture medium of mammalian cells
Keywords: دی هیدروفلات ردوکتاز; CHO-K1/dhfr-; Ni-chelate column; Non-ionic detergent; Coelenterazine; GLase; Gaussia luciferase; GLase-His; histidine-tagged Gaussia luciferase; CHO; Chinese hamster ovary; dhfr; dihydrofolate reductase; Imax; maximum intensity of luminescence; rlu; relat
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics
Keywords: دی هیدروفلات ردوکتاز; ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy
Association of MTHF 677TT with adverse drug reactions and RFC G80A with non-response and adverse drug reactions in methotrexate therapy
Keywords: دی هیدروفلات ردوکتاز; Adverse drug reaction; Dihydrofolate reductase; Drug response; Methylenetetrahydrofolate reductase; Pharmacogenetics;
Emerging role of lncRNAs in systemic lupus erythematosus
Keywords: دی هیدروفلات ردوکتاز; AR5; accessible region 5; C3; complement 3; CNS3; conserved noncoding sequence 3; DBD; DNA-binding domain; DCs; dendritic cells; DDX5; RNA helicase DEAD-box protein 5; DHFR; dihydrofolate reductase; DNMTs; DNA methyltransferases; ERα; estrogen receptor Î
Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopy
Keywords: دی هیدروفلات ردوکتاز; bsAb; bispecific antibody; CHO; chinese hamster ovary; ER; endoplasmic reticulum; IgG; Immunoglobulin G; DTE; difficult-to-express; DHFR; dihydrofolate reductase; MTX; Methotrexate; VCD; viable cell density; qRT-PCR; quantitative real-time polymerase chai
Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents
Keywords: دی هیدروفلات ردوکتاز; Pj; Pneumocystis jirovecii; PCP; Pneumocystis pneumonia; ART; antiretroviral therapy; TMP; trimethoprim; SMX; sulfamethoxazole; DHFR; dihydrofolate reductase; DHPS; dihydropteroate synthase; PTX; piritrexim; TMQ; trimetrexate; PC; Pneumocystis carinii; DH
5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation
Keywords: دی هیدروفلات ردوکتاز; Adamantan; Thiadiazole; Thiazolidinone; Antibacterial; Antifungal; Docking; MurB; MurA; CYP51; Dihydrofolate reductase;
1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity
Keywords: دی هیدروفلات ردوکتاز; Dihydrofolate reductase (DHFR); Antimycobacterial agent; Tuberculosis (TB); 1,3,5-triazaspiro[5.5]undeca-2,4-diene; DHFR; dihydrofolate reductase; DMPK; drug metabolism and pharmacokinetics; FRLM; female rat liver microsomes; HBA; hydrogen bond acceptors;
Alpha repeat proteins (αRep) as expression and crystallization helpers
Keywords: دی هیدروفلات ردوکتاز; PCA; protein complementation assay; DHFR; dihydrofolate reductase; LIC; ligation independant cloning; Artificial repeat proteins; Protein library; Crystallization helper; Protein complementation assay; Fusion protein;