کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8524581 1557936 2018 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Emerging role of lncRNAs in systemic lupus erythematosus
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Emerging role of lncRNAs in systemic lupus erythematosus
چکیده انگلیسی
Long non-coding RNAs (lncRNAs), defined as ≥200 base pairs in length but have little translation potential, play a key role in imprinting control, immune cell differentiation, apoptosis and immune responses. Recently, many potential lncRNAs have been revealed to contribute to a new layer of molecular regulation of systemic lupus erythematosus (SLE). Immune-related functional lncRNAs may serve as novel therapeutic targets and disease biomarkers to provide potential support for clinic treatment in this disease. In this review, we will briefly introduce the identification, biogenesis and functions of lncRNAs, and summarize recent advance in the role of lncRNAs in SLE.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 106, October 2018, Pages 584-592
نویسندگان
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