Keywords: عامل هسته ای سلول های T فعال شده; AC; adenylyl cyclase; ALG-2; apoptosis-linked gene 2 product; Alix; ALG-2-interacting protein X; Bcl10; B-cell lymphoma/leukemia protein 10; CaM; calmodulin; CaM-BD; CaM-binding domain; CaM-BP; CaM-binding protein; CARD; caspase-recruitment domain; Carma1
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Keywords: عامل هسته ای سلول های T فعال شده; AP-1; activating protein 1; APC; antigen presenting cell; CAR; chimeric antigen receptors; Cbl-b; casitas B-lineage lymphoma; DAG; diacylglycerol; cSMAC; central supramolecular activation cluster; CTLA4; cytotoxic T lymphocyte antigen 4; dSMAC; distal sup
Keywords: عامل هسته ای سلول های T فعال شده; DCA; dichloroacetate; FAO; fatty acid oxidation; GO; glucose oxidation; HIF-1; hypoxia-inducible factor 1; CaL channels; L-type calcium channels; NFATs; nuclear factor of activated T cells; NO; nitric oxide; MCT-PAH; monocrotaline-induced PAH; PAH; pulmon
Keywords: عامل هسته ای سلول های T فعال شده; Hydrogen; DNA microarray; Gene set enrichment analysis; Histone H3K27; Mitochondrial unfolded protein response; CDAA; Choline-deficient l-amino acid-defined; Fgf21; Fibroblast growth factor 21; GEO; Gene Expression Omnibus; GSEA; Gene set enrichment analy
Keywords: عامل هسته ای سلول های T فعال شده; PKC; protein kinase C; NFAT; nuclear factor of activated T cells; MST; mean survival time; CNIs; calcineurin inhibitors; SEM; standard error of the mean; ANOVA; analysis of variance; IL; interleukin; TNF; tumor necrosis factor; PCR; polymerase chain react
Keywords: عامل هسته ای سلول های T فعال شده; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; AMP-activated protein kinase; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CA; carbonic anhydrase; CAF; cancer-associated fibroblast; CHC; α-cyano-4-hydr
Keywords: عامل هسته ای سلول های T فعال شده; ACTH; adrenocorticotropic hormone; DN; double negative; Dll; delta-like ligand; DP; double positive; HPA-axis; hypothalamus-pituitary-adrenal axis; HSD; hydroxysteroid-dehydrogenase; IL; interleukin; SP; single positive; IFN; interferon; TEC; thymic epith
Keywords: عامل هسته ای سلول های T فعال شده; AA; arachidonic acid; aP2 (or FABP4); adipocyte protein 2; BMD; bone mass density; BMP-2; bone morphogenic protein-2; CE; cholesterol esters; CHL; cholesterol; cAMP; cyclic 3,5-adenosine monophosphate; CLA; conjugated isomers of linoleic acid; COX; cycloo
Keywords: عامل هسته ای سلول های T فعال شده; NFAT; nuclear factor of activated T cells; CFSE; carboxylfluorescein diacetate succinimidyl ester; CSA; cyclosporine; PRD; prednisolone; MPA; mycophenolic acid; MMF; mycophenolate mofetil; CNI; calcineurin inhibitor; CMV; cytomegalovirus; VZV; varicella z
Keywords: عامل هسته ای سلول های T فعال شده; AKAPs; A-kinase anchoring proteins; AKT; protein kinase b; Ang-II; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BH4; tetrahydrobiopterin; CaMKII; Ca/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CHF; chronic heart fa
Keywords: عامل هسته ای سلول های T فعال شده; AP-1; activator protein-1; BLNK; B cell linker protein; BTK; Bruton's tyrosine kinase; CCT; choline cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CEPT1; choline/ethanolamine phosphotransferase 1; Cer; ceramide; CK; choline kinase; CPT1; ch
Increased TRPC6 expression is associated with tubular epithelial cell proliferation and inflammation in diabetic nephropathy
Keywords: عامل هسته ای سلول های T فعال شده; DN; diabetic nephropathy; NFAT; nuclear factor of activated T cells; qRT-PCR; quantitative real-time PCR; TECs; tubular epithelial cells; TRPC6; transient receptor potential channel 6; Diabetic nephropathy; Tubular epithelial cells; Proliferation; Inflamm
Long non-coding RNA NRON is downregulated in HCC and suppresses tumour cell proliferation and metastasis
Keywords: عامل هسته ای سلول های T فعال شده; Long non-coding RNA; NRON; Nuclear factor of activated T cells; Hepatocellular carcinoma; Metastasis;
A critical appraisal of the role of intracellular Ca2+-signaling pathways in Kawasaki disease
Keywords: عامل هسته ای سلول های T فعال شده; [Ca2+]cyt; free cytosolic Ca2+ concentration; CRAC; Ca2+-release activated Ca2+ entry; EBV; Epstein-Barr virus; ER; endoplasmic reticulum; IP3; inositol 1,4,5-trisphosphate; IP4; inositol 1,3,4,5-tetrakisphosphate; IP3R; IP3 receptor; KD; Kawasaki disease
Emerging role of lncRNAs in systemic lupus erythematosus
Keywords: عامل هسته ای سلول های T فعال شده; AR5; accessible region 5; C3; complement 3; CNS3; conserved noncoding sequence 3; DBD; DNA-binding domain; DCs; dendritic cells; DDX5; RNA helicase DEAD-box protein 5; DHFR; dihydrofolate reductase; DNMTs; DNA methyltransferases; ERα; estrogen receptor Î
Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease
Keywords: عامل هسته ای سلول های T فعال شده; AChE; acetylcholine esterase; AD; Alzheimer's disease; AP1; activator protein 1; APP; amyloid precursor protein; Aβ; amyloid beta; BACE1; β-site of APP cleaving enzyme; Bax; Bcl-2-associated X protein; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma
Activation of Serine One-Carbon Metabolism by Calcineurin Aβ1 Reduces Myocardial Hypertrophy and Improves Ventricular Function
Keywords: عامل هسته ای سلول های T فعال شده; cardiac function; cell signaling; hypertrophy; metabolism; ATF4; activating transcription factor 4; BSO; L-buthionine-sulfoximine; GSH; reduced glutathione; LVEF; left ventricular ejection fraction; LVMi; left ventricular mass index; mTOR; mechanistic tar
Association of FoxP3 promoter polymorphisms with the risk of Graves' disease in ethnic Kashmiri population
Keywords: عامل هسته ای سلول های T فعال شده; AID; autoimmune disorder; FoxP3; Forkhead box P3; GD; Graves' disease; GO; Graves' ophthalmopathy; NFAT; nuclear factor of activated T cells; RFLP; restriction fragment length polymorphism; SNPs; single-nucleotide polymorphisms; TRAB; thyroid receptor ant
Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease
Keywords: عامل هسته ای سلول های T فعال شده; ER; endoplasmic reticulum; GASE; Golgi apparatus stress recognition element; HHD; Hailey-Hailey Disease; KD; knockdown; NFAT; nuclear factor of activated T cells; NT; non-targeting; ROI; region of interest; SICE; store-independent Ca2+ entry; SOCE; store-
Inhibition of Orai1-mediated Ca2+ entry limits endothelial cell inflammation by suppressing calcineurin-NFATc4 signaling pathway
Keywords: عامل هسته ای سلول های T فعال شده; Orai1; Nuclear factor of activated T cells; Inflammation; Endothelial cells;
The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy
Keywords: عامل هسته ای سلول های T فعال شده; αβ; alpha beta; ADCC; antibody-dependent cellular cytotoxicity; APC; antigen-presenting cell; BrHPP; bromohydrin pyrophosphate; BTLA; B and T lymphocyte attenuator; CAR; chimeric antigen receptor; DC; dendritic cell; γc; common gamma; γδ; gamma delta
Optimizing conventional DMARD therapy for Sjögren's syndrome
Keywords: عامل هسته ای سلول های T فعال شده; 6-MP; 6-mercaptopurine; 6-T-GTP; 6-thioguanine triphosphate; ABT; abatacept; Ach; acetylcholine; ALAT; alanine amino transferase; AZA; azathioprine; BAFF; B cell activating factor; Bcl-6; B cell lymphoma 6; bDMARDs; biological disease modifying antirheuma
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: عامل هسته ای سلول های T فعال شده; Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
The role of T cells in the pathogenesis of Parkinson's disease
Keywords: عامل هسته ای سلول های T فعال شده; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APC; antigen-presenting cell; AQP4; Aquaporin-4; BBB; blood-brain barrier; BCL6; B cell lymphoma 6; BCR; B cell receptor; BEC; brain endothelial cells; CCL20; C-C motif ligand 20; CCR2; C-C
Regulation of CacyBP/SIP expression by NFAT1 transcription factor
Keywords: عامل هسته ای سلول های T فعال شده; CacyBP/SIP; calcyclin binding protein/Siah-1 interacting protein; ChIP; chromatin immunoprecipitation; NFAT; nuclear factor of activated T cells; PAGE; polyacrylamide gel electrophoresis; PDTC; pyrrolidine dithiocarbamate; SDS; sodium dodecyl sulfate; Cac
TonEBP/NFAT5 regulates downstream osmoregulatory proteins during freeze-thaw stress in the wood frog
Keywords: عامل هسته ای سلول های T فعال شده; Freezing; Thaw; Rana sylvatica; Osmotic stress; Cryoprotection; Nuclear factor of activated T cells;
Pharmacophore guided discovery of small-molecule interleukin 15 inhibitors
Keywords: عامل هسته ای سلول های T فعال شده; Interleukin-15; IL-15; IL-15Rα; IL-15 inhibitor; IL-15Rα inhibitor; Cefazolin; Psoriasis; Rheumatoid arthritis; IL; interleukin; IL-15Rα; IL-15 specific receptor alpha; IL-2/IL-15Rβ, CD122; IL-2/IL-15 specific receptor beta; γc, CD123; common cytokin
Signaling via G proteins mediates tumorigenic effects of GPR87
Keywords: عامل هسته ای سلول های T فعال شده; 7TM; seven transmembrane; AC; adenylate cyclase; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding protein; CSC; cancer stem cells; CysLTs; cysteinyl-leukotrienes; ELISA; Enzyme-linked immunosorbent assay
Research paperCharacterization of FcγRIIIA effector cells used in in vitro ADCC bioassay: Comparison of primary NK cells with engineered NK-92 and Jurkat T cells
Keywords: عامل هسته ای سلول های T فعال شده; mAbs; monoclonal antibodies; Fab; fragment antigen-binding; Fc; fragment crystallizable; NK cells; natural killer cells; ADCC; antibody-dependent cell-mediated cytotoxicity; MOA; mechanisms of action; NFAT; nuclear factor of activated T cells; T cells; th
Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro/vivo
Keywords: عامل هسته ای سلول های T فعال شده; SEP; A polysaccharide isolated from Strongylocentrotus nudus egg; TLR; toll-like receptor; NKG2D; natural-killer group 2 member D; DAP10; DNAX-associated protein 10; Akt; protein kinase B; MICA; MHC class I-related chain A; sMICA; soluble MHC class I-rela
Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases
Keywords: عامل هسته ای سلول های T فعال شده; ADP; adenosine 5â²-diphosphate; AgRP; agouti-related peptide; AMPK; 5â²-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5â²-triphosphate; BN-PAGE; blue native-p
Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas
Keywords: عامل هسته ای سلول های T فعال شده; IHC; immunohistochemistry; KEGG; Kyoto Encyclopedia of Genes and Genomes; MCC; Merkel cell carcinoma; MCPyV; Merkel cell polyomavirus; NFAT; nuclear factor of activated T cells; P-CREB; phosphorylated CRE-binding protein; P-STAT; phosphorylated signal tra
Peptides derived from transcription factor EB bind to calcineurin at a similar region as the NFAT-type motif
Keywords: عامل هسته ای سلول های T فعال شده; Calcineurin; Transcription factor EB; Nuclear factor of activated T cells; LxVP-type motif; TFEB-YLENP peptide;
Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors
Keywords: عامل هسته ای سلول های T فعال شده; Endothelin-1; Cardiac hypertrophy; Signalling; MAPK; GPCRs; Act D; actinomycin D; Ang II; angiotensin II; ANF; atrial natriuretic factor; BNP; brain natriuretic factor; CN; calcineurin; CVD; cardiovascular disease; ara-C; cytosine b-d-arabinofuranoside; D
MAP kinase signaling and Elk1 transcriptional activity in hibernating thirteen-lined ground squirrels
Keywords: عامل هسته ای سلول های T فعال شده; ATF2; activating transcription factor 2; bZIP; basic leucine zipper; Ca2Â +; Â calcium; CREB; cAMP-responsive element binding protein; DPI-ELISA; DNA-protein interaction enzyme-linked immunosorbent assay; EA; early arousal; EC; euthermic control; Elk1; ET
Development of CAR T cells designed to improve antitumor efficacy and safety
Keywords: عامل هسته ای سلول های T فعال شده; 28z; CD28 + CD3ζ; 4-1BBL; 4-1BB ligand; B-ALL; B cell acute lymphatic leukemia; BBz; 4-1BB + CD3ζ; CAR; chimeric antigen receptor; CD40L; CD40 ligand; CRS; cytokine release syndrome; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DCs; dendriti
Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen
Keywords: عامل هسته ای سلول های T فعال شده; House dust mite; allergic asthma; eosinophils; protein kinase Cθ; innate lymphoid cells; nuclear factor of activated T cells; interferon regulatory factor 4; BAL; Bronchoalveolar lavage; BALF; Bronchoalveolar lavage fluid; BMDC; Bone marrow-derived den
Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer
Keywords: عامل هسته ای سلول های T فعال شده; Pancreatic cancer; T cells; Exhaustion; Immunotherapy; ACT; adoptive cell transfer; AP-1; activator protein-1; APC; antigen-presenting cells; CAR; chimeric antigen receptor; CTL; cytotoxic T cells; CTLA-4; cytotoxic T lymphocyte antigen 4; FDA; US Food an
Research paperRapamycin safeguards lymphocytes from DNA damage accumulation in vivo
Keywords: عامل هسته ای سلول های T فعال شده; CNI; calcineurin inhibitors; CSA; cyclosporine A; IL-2; interleukin-2; mTOR; mammalian Target Of Rapamycin; NFAT; nuclear factor of activated T cells; PBL; peripheral blood lymphocytes; PHA; phytohemagglutinin; RIN; RNA integrity; ROS; reactive oxygen spe
Intracellular Ca2+ signaling and Ca2+ microdomains in the control of cell survival, apoptosis and autophagy
Keywords: عامل هسته ای سلول های T فعال شده; Apoptosis; Autophagy; Endoplasmic reticulum; IP3 receptor; Lysosomes; Mitochondria; AMBRA1; autophagy/Beclin 1 regulator 1; AMPK; AMP-activated kinase; ATF4; activating transcription factor-4; Atg; autophagy-related; BIRD-2; Bcl-2/IP3R disruptor-2; CREB;
Adhesion GPCRs in immunology
Keywords: عامل هسته ای سلول های T فعال شده; GPCR; G protein-coupled receptor; aGPCR; adhesion G protein-coupled receptor; ADGR; general adhesion GPCR name followed by class and subtype specific code; 7TM; 7 transmembrane; VLGR1; very large G protein-coupled receptor 1; ECD; extracellular domain; GP
Beyond CTLA-4 and PD-1: Orphan nuclear receptor NR2F6 as T cell signaling switch and emerging target in cancer immunotherapy
Keywords: عامل هسته ای سلول های T فعال شده; AP-1; activation protein 1; CTLA-4; cytotoxic T lymphocyte-associated protein-4; GM-CSF; granulocyte-macrophage colony-stimulating factor; IL-2; interleukin 2; IFNÆ´; interferon Æ´; NFAT; nuclear factor of activated T cells; NR2F6; nuclear receptor subfam
Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage
Keywords: عامل هسته ای سلول های T فعال شده; ACs; articular chondrocytes; H3K4me2; histone 3 lysine 4 dimethylation; OA; osteoarthritis; WT; wild-type; IHC; immunohistochemistry; HE; haematoxylin and eosin; qPCR; quantitative real-time RT-PCR; P1; first passage of cultured cells; MeDIP; methylated D
T helper 2 and T follicular helper cells: Regulation and function of interleukin-4
Keywords: عامل هسته ای سلول های T فعال شده; Th2; T helper 2; Tfh; T follicular helper; IL; Interleukin; Ig; Immunoglobulin; STAT; signal transduction and activator of transcription; TCR; T cell receptor; NFAT; nuclear factor of activated T cells; IRF4; Interferon regulatory factor 4; ERK; extracell
PACAP and VIP signaling in chondrogenesis and osteogenesis
Keywords: عامل هسته ای سلول های T فعال شده; ALP; alkaline phosphatase; BMP; bone morphogenetic protein; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding protein; ECM; extracellular matrix; HH; Hedgehog; IHH; Indian Hedgehog; MAPK; mitogen-activated protein kinase; NFAT; nuc
RARγ is a negative regulator of osteoclastogenesis
Keywords: عامل هسته ای سلول های T فعال شده; RAR; retinoic acid receptor; RXR; retinoid X receptor; ATRA; all-trans retinoic acid; BMM; bone marrow macrophages; G-CSF; granulocyte colony stimulating factor; RANKL; receptor activator of nuclear factor kappa-B; NFAT; nuclear factor of activated T cell
Role of PRDM16 and its PR domain in the epigenetic regulation of myogenic and adipogenic genes during transdifferentiation of C2C12 cells
Keywords: عامل هسته ای سلول های T فعال شده; C/EBP; CCAAT/enhancer binding protein; ChIP; chromatin immunoprecipitation; H3K4me3; histone H3 lysine 4 trimethylation; H3K9me1; H3K9 monomethylation; mCK; muscle creatine kinase; MEF; Myocyte-specific enhancer factor; MyHC; myosin heavy chain; NFAT; nuc
Modulation of TCR responsiveness by the Grb2-family adaptor, Gads
Keywords: عامل هسته ای سلول های T فعال شده; DAG; diacylglycerolDSB, double strand break; Gads; Grb2-related adaptor downstream of Shc; Indel; insertion and deletion mutation; GFP; green fluorescent protein; Grap; Grb2-related adaptor protein; Grb2; growth factor receptor-bound 2; IRES; internal rib
Interleukin-6 reduces NMDAR-mediated cytosolic Ca2+ overload and neuronal death via JAK/CaN signaling
Keywords: عامل هسته ای سلول های T فعال شده; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CaN; calcineurin; CGNs; cerebellar granule neurons; CNS; central nervous system; Ifen; ifenprodil; IL-6; interleuki
CaMKII regulates intracellular Ca2+ dynamics in native endothelial cells
Keywords: عامل هسته ای سلول های T فعال شده; KCa; calcium-activated potassium channel; NO; nitric oxide; NOS3; endothelial nitric oxide synthase; CaMKII; Ca2+/calmodulin kinase II; ER; endoplasmic reticulum; KN-93; (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl) amino-N-(4-chlorocinnamyl)-N-met