Keywords: CRPC; aggressive variant; neuroendocrine; epigenetics; therapy; EZH2;
مقالات ISI (ترجمه نشده)
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Keywords: Protein methyltransferase; Protein methylation; Squamous cell carcinoma of the head and neck; NSD1; NSD2; NSD3; EHMT2; EZH2; PRMT1; PRMT5;
Keywords: Sporadic/hereditary pituitary tumors; Whole genome/exome sequencing; USP8 mutation; Pituitary adenoma progression; Pituitary carcinoma; Pituitary tumor senescence; AIP; aryl hydrocarbon-interacting protein; BC; bromocriptine; bFGF; basic fibroblast growth
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
Keywords: ACVR1; Activin A receptor type1; ATRX; A-thalassemia/mental retardation syndrome X-linked; BMP; Bone morphogenetic protein; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CNS; Central nervous system; DAXX; Death domain-associated protein; DNMT; DNA
Keywords: ac; acetylation; BET; bromodomain and extra terminal family proteins; BMP7; bone morphogenic protein 7; BRD4; bromodomain-containing protein 4; bp; base pairs; CKD; chronic kidney disease; CTGF; connective tissue growth factor; DDR; DNA damage response; D
Keywords: BALs; Broncho Alveolar Lavages; CSE; Cigarette Smoke Extract; COPD; Chronic Obstructive Pulmonary Disease; EVs; Extracellular Vesicles; EZH2; Enhancer of zeste homolog 2; HMGA2; High-mobility group AT-hook 2; IARC; International Agency For Research On Can
Keywords: TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: 5-HT(2B); 5-hydroxytryptamine 2B receptor; ACE; angiotensin-converting enzyme; AMPK; AMP-activated protein kinase; ARB; AT1R blocker; ASK1; apoptosis signal-regulating kinase 1; AT1R; angiotensin II type 1 receptor; ATX; autotaxin; BDL; bile duct ligation
Keywords: BPA; bisphenol A; CpG; 5â²-C-phosphate-G-3â²; DDT; dichlorodiphenyltrichloroethane; DEET; N,N-diethyl-meta-toluamide; DEHP; bis(2-ethylhexyl)phthalate; DES; diethylstilbestrol; DNMT; DNA methyltransferase; DOHaD; Developmental Origins of Health and Dise
Keywords: CSCs; cancer stem cells; PcG; polycomb gene; PRC; polycomb repressive complex; CpG; 5â²-C-phosphate-G-3â²; DNMT; DNA methyltransferase; EZH2; Enhancer Zeste Homologue 2; Hh; Hedgehog; MSP; methylation specific PCR; HAT; histone acetyltransferase; HDAC;
Keywords: AIs; aromatase inhibitors; AMPK; Adenosine Monophosphate-Activated Protein Kinase; AR; androgen; ATM; Ataxia Telangiectasia Mutated; ATP; Adenosine Triphosphate; BCSS; breast cancer specific survival; CK-MB; Creatine Kinase-MB; CREB1; cAMP Response Elemen
Keywords: CCA; cholangiocarcinoma; OS; overall survival; miRNA; microRNA; TSG; tumor suppressor genes; ICC; intrahepatic cholangiocarcinoma; OV; Opisthorchis viverrini; CpG; scytosine guanine dinucleotides; DNMT; DNA methyltransferases; EZH2; zeste homolog 2; RASSF
Keywords: HCC; hepatocellular carcinoma, GPC3, glypican3; GS; glutamine synthetase; HSP70; heat shock protein 70; NTLT; non-tumorous liver tissue; HCA; hepatocellular adenoma; FNH; focal nodular hyperplasia; 14-3-3S; 14-3-3Sigma; 2D-DIGE; two-dimensional difference
Keywords: 5-aza-CdR; 5-aza-2â²-deoxycytidine; AML; acute myeloid leukemia; ANRIL; antisense non-coding RNA in the INK4 locus; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A; CoREST; co-repressor for element-1-silencing transcription factor
Keywords: α-KG; alpha-ketoglutarate; 2-HG; 2-hydroxyglutarate; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AML; acute myeloid leukemia; ASXL1; additional sex combs-like 1; AZA; azacytidine; CMML; chronic myelomonocytic leukemia; DAC; decitabine; DNMT3A;
Keywords: ASXL1; BAP1; CREBBP; DNMT3A; EP300; EZH2
Keywords: lncRNA; long/large noncoding RNA; Xist; X-inactive specific transcript; mESC; mouse embryonic stem cell; Evf2; embryonic ventral forebrain 2; Six3os; sine oculis-related homeobox 3 homolog, opposite strand; Dlx1as; distal-less homeobox 1, antisense; EGO;
Keywords: Somatic mutation; SNP; KMT; KDM; EZH2; Histone;
Keywords: ECMs; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β1; transforming growth factor-β1; Ang-II; angiotension II; DNMTs; DNA methyltransferases; 5-Aza-dC; 5-Aza-2â²-deoxycytidine; EZH2; Enhancer of zeste homolog 2; HDAC; histone deacetylases;
Keywords: TH; Thyroid hormone; TR; Thyroid hormone receptor; T3; 3,5,3â² triiodothyronine; TRE; TH response element; DR; direct repeat; IR; inverted repeat or palindrome; ER; everted repeat; RXR; retinoic acid X receptor; dp; dominant positive; dn; dominant negati
LncRNA HOXA-AS2 and its molecular mechanisms in human cancer
Keywords: lncRNA; HOXA-AS2; Diagnosis; Therapeutic target; Prognosis; APL; Acute promyelocytic leukemia; ATRA; All trans retinoic acid; Bax; BCL2-Associated X; BC; Breast cancer; Bcl-2; B-cell lymphoma-2; c-Myc; MYC proto-oncogene; CRC; Colorectal cancer; DDIT3; DN
LncRNA LINC00968 accelerates the proliferation and fibrosis of diabetic nephropathy by epigenetically repressing p21 via recruiting EZH2
Keywords: Diabetic nephropathy; LINC00968; Proliferation; p21; EZH2;
An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma
Keywords: Thymoma; Thymic carcinoma; EZH2; C-KIT; CD205; Immunohistochemistry;
EZH2 regulates dental pulp inflammation by direct effect on inflammatory factors
Keywords: EZH2; enhancer of zeste homolog 2; HDPCs; human dental pulp cells; ChIP; chromatin immunoprecipitation; PRC2; polycomb repressor complex 2; DZNep; 3-deazaneplanocin A; MAPK; mitogen-activated protein kinases; EZH2; Dental pulp inflammation; Inflammatory f
The long non-coding RNA PCSEAT exhibits an oncogenic property in prostate cancer and functions as a competing endogenous RNA that associates with EZH2
Keywords: Prostate cancer; PCSEAT; EZH2; Competing endogenous RNA; Exosome;
GSK126 alleviates the obesity phenotype by promoting the differentiation of thermogenic beige adipocytes in diet-induced obese mice
Keywords: GSK126; H3K27me3; Ezh2; Obesity; Beige adipocyte;
Effects of microRNAs on skeletal muscle development
Keywords: HDAC4; histone deacetylase 4; SRF; serum response factor; Pax3; paired box protein pax-3; Pax7; paired box protein pax-7; 3â²UTR; 3â² untranslated region; MEF2A; myocyte-specific enhancer factor 2A; Mef2d; myocyte-specific enhancer factor 2D; Myf5; myog
Long noncoding RNA TP73-AS1 promotes non-small cell lung cancer progression by competitively sponging miR-449a/EZH2
Keywords: Non-small cell lung cancer; TP73-AS1; miR-449a; EZH2; ceRNA;
Genetic interaction between Gli3 and Ezh2 during limb pattern formation
Keywords: Skeletal pattern; Limb bud; Mouse embryo; Gli3; Ezh2; Genetic interaction;
Anti-tumor and anti-metastasis activities of honey bee larvae powder by suppressing the expression of EZH2
Keywords: HLP; honey bee larvae powder; HLE; honey bee larvae powder extract; TNF-α; tumor necrosis factor alpha; CCK-8; cell counting Kit-8; H&E; hematoxylin and eosin; TPC; total phenolic content; TFC; total flavonoids content; EZH2; Enhancer of Zeste Homolog 2;
Anti-proliferative benefit of curcumol on human bladder cancer cells via inactivating EZH2 effector
Keywords: Curcumol; Bladder cancer; Proliferation; Apoptosis; EZH2;
Roles of microRNA in prostate cancer cell metabolism
Keywords: AMPK; adenosine monophosphate-activated protein kinase; HIF-1α; hypoxia-inducible factor 1-alpha; mTOR; mammalian target of rapamycin; PI3K/AKT; phosphatidylinositol 3-kinase; ATP; adenosine triphosphate; TCA cycle; tricarboxylic acid cycle; GLUTs; gluco
X-inactive-specific transcript: A long noncoding RNA with complex roles in human cancers
Keywords: AR; androgen receptor; ATG7; autophagy related 7; Bcl2; B-cell lymphoma-2; BRCA1; breast cancer-associated protein 1; CCND1; cyclin D1; CDK4/6; cyclin dependent kinase 4/6; CDX1; caudal type homeobox 1; CRC; colorectal cancer; EMT; epithelial mesenchymal
microRNA-124a suppresses PHF19 over-expression, EZH2 hyper-activation, and aberrant cell proliferation in human glioma
Keywords: Glioma; EZH2; PRC2; PHF19; miR-124a;
FOXP4-AS1 participates in the development and progression of osteosarcoma by downregulating LATS1 via binding to LSD1 and EZH2
Keywords: Osteosarcoma; FOXP4-AS1; LSD1; EZH2; LATS1;
LncRNA SOX21-AS1 is associated with progression of hepatocellular carcinoma and predicts prognosis through epigenetically silencing p21
Keywords: SOX21-AS1; EZH2; p21; HCC; Progression;
MicroRNA-298 represses hepatocellular carcinoma progression by inhibiting CTNND1-mediated Wnt/β-catenin signaling
Keywords: HCC; hepatocellular carcinoma; HBV; hepatitis B virus; miRNAs; microRNAs; EMT; epithelial-mesenchymal transition; EZH2; enhancer of zeste 2; CTNND1; catenin delta 1; RT-qPCR; reverse transcription-quantitative polymerase chain reaction; HRP; horseradish p
Emerging role of lncRNAs in systemic lupus erythematosus
Keywords: AR5; accessible region 5; C3; complement 3; CNS3; conserved noncoding sequence 3; DBD; DNA-binding domain; DCs; dendritic cells; DDX5; RNA helicase DEAD-box protein 5; DHFR; dihydrofolate reductase; DNMTs; DNA methyltransferases; ERα; estrogen receptor Î
Comprehensive Genomic Sequencing of Urothelial Tumors Identifies Rare SMARCB1 (INI-1)-Deficient Carcinomas of the Urinary System
Keywords: EZH2; Genomic profiling; MVAC; SMARCB1 protein; Urologic neoplasms;
Alterations of DNA methylation in parathyroid tumors
Keywords: Parathyroid tumors; Hyperparathyroidism; PTH; Methylation; Chromatin modifiers; Histones; MEN1; multiple endocrine neoplasia type 1; HPT-JT; hyperparathyroidism- jaw tumors; CpG; cytosine phosphate guanine; 5hmc; 5-hydroxymethylcytosine; TET1; tet (ten-el
Double sword role of EZH2 in leukemia
Keywords: EZH1,2; enhancer of Zeste 1 and 2; SUZ12; suppressor of zeste 12 homolog; EED; embryonic ectoderm development; AEBP2; adipocyte enhancer-binding protein 2; RBAP46/48; retinoblastoma binding proteins 46 and 48; PRC; polycomb-repressive complex; PcG; Polyco
High immunoexpression of Ki67, EZH2, and SMYD3 in diagnostic prostate biopsies independently predicts outcome in patients with prostate cancer
Keywords: Biopsy; EZH2; Ki67; Prognosis; Prostate cancer; SMYD3;
Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair
Keywords: CDK4/6; cyclin-dependent kinases 4 and 6; CDK2; cyclin-dependent kinase 2; iCDK4/6; inhibitor of CDK4/6; LEE011; inhibitor of CDK4/6, ribociclib, Kisqali; PD0332991; inhibitor of CDK4/6, palbociclib, Imbrance; NU6140; cyclin-dependent kinase 2 (CDK2) inhi
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis
Keywords: carnosol (PubChem CID:442009); resveratrol (PubChem CID:445154); DZNep; 3-Deazaneplanoci A; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CS; carnosol; CCl4; carbon tetrachloride; H3K27me3; catalyzes trimethylation of lysine 27 on histon
The EZH2- H3K27me3-DNMT1 complex orchestrates epigenetic silencing of the wwc1 gene, a Hippo/YAP pathway upstream effector, in breast cancer epithelial cells
Keywords: Breast cancer; Kibra; Methylation; PRC2 core complex; EZH2; Hippo/YAP signaling pathway;
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Regulatory identification of BPA as an endocrine disruptor: Context and methodology
Keywords: Bisphenol A; Endocrine disruption; ED; SVHC; Substance of very high concern; REACh; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail (French Agency for Food, Environmental and Occupational Health & Sa
Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma
Keywords: APCDD1; adenomatosis polyposis coli downregulated 1; AP2; activating protein 2; bHLH; basic helix-loop-helix; B-FABP; brain fatty acid-binding protein; CoRE; composite response element; EZH2; enhancer of zest homolog 2; GBM; glioblastoma; GO; gene ontolog
Epigenetic mechanisms regulating T-cell responses
Keywords: Epigenetics; gene regulation; enhancer; promoter; chromatin accessibility; histone modifications; DNA methylation; transcription factor binding; T-cell development; T-cell function; T-cell exhaustion; regulatory T cells; tissue specificity; ATAC; Assay fo