دانلود مقالات ISI درباره Ezh2 + ترجمه فارسی

Oncogenic long noncoding RNA MALAT1 and HCV-related hepatocellular carcinoma

Keywords: AFP; alpha fetoprotein; AUC; area under the ROC curve; cDNA; complementary DNA; DRAIC; Down-regulated RNA In Cancer; EMT; epithelial-mesenchymal transition; eRNAs; enhancer RNAs; EZH2; Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit; GAS5; growt

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

RARA and RARG gene downregulation associated with EZH2 mutation in acute promyelocytic-like morphology leukemia

Keywords: APL-like leukemia; RARA; RARG; EZH2; NGS; Epigenetic silencing;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop

Keywords: SNAIL; Snail family transcriptional repressor; ZEB; Zinc finger E-box binding homeobox; BMP1; Bone Morphogenetic protein1; TWIST; twist family bHLH transcription factor 1; GSC; goosecoid hemeobox; TGF-β; transforming growth factor beta; NPC; nasopharynge

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma

Keywords: c-Myc/EZH2 double positive; microRNA-26a; Epigenetics modification; Metastasis; Advanced hepatocellular carcinoma; AAV; adeno-associated virus; CDK8; cyclin dependent kinase 8; CTDSP2; CTD small phosphatase 2; DEN; diethylnitrosamine; DZNep; 3-deazaneplan

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

EZH2 is upregulated in the proliferation centers of CLL/SLL lymph nodes

Keywords: Proliferation center; CLL/SLL; EZH2; miR-26a; C-myc;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2

Keywords: lncRNAs; long noncoding RNAs; ceRNA; competing endogenous RNAs; miR-363-5p; hsa-miRNA-450b-5p; LINC00319; long intergenic non-protein coding RNA 319; ANOVA; One-Way Analysis of Variance; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IHC; immunohistoche

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Epigenetics in myelodysplastic syndromes

Keywords: MDS; Epigenetics; ASXL1; DNMT3A; EP300; EZH2; IDH1; IDH2; KDM2B; KDM5A; KDM6A; MLL; MLL2; MLL3; MLL5; TET2; WT1; Hypomethylating agent; HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Novel combination of histone methylation modulators with therapeutic synergy against acute myeloid leukemia in vitro and in vivo

Keywords: LSD1; EZH2; Acute myeloid leukemia; Synergistic effect; Drug combination;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Hsa-microRNA-101-3p expression in human urinary bladder cancer: Correlation with tumor pathology

Keywords: BC; Bladder cancer; Bcl-2; B cell lymphoma-2; BTCC; Bladder transitional cell carcinoma; c-Met; Tyrosine-protein kinase Met; EZH2; Enhancer of zeste homologue 2; FGFR3; Fibroblast growth factor receptor 3; Hsa-microRNA-101-3p; Homosapiens micro RNA-101 st

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Interactions between microRNAs and long non-coding RNAs in cardiac development and repair

Keywords: AAV; adeno-associated virus; AMI; acute myocardial infarction; APF; autophagy promoting factor; Bvht; Braveheart; CARL/Carl; cardiac apoptosis-related lncRNA; CARMEN/Carmen; cardiac mesoderm enhancer-associated non-coding RNA; CHAER/Chaer; cardiac-hypertr

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Chromatin organization regulated by EZH2-mediated H3K27me3 is required for OPN-induced migration of bone marrow-derived mesenchymal stem cells

Keywords: Osteopontin; Bone marrow-derived mesenchymal stem cells (BMSCs); Migration; Chromatin; Nuclear mechanics; ERK1/2 signalling; AFM; atomic force microscopy; BMSCs; bone marrow-derived mesenchymal stem cells; BSA; bovine serum albumin; CSK buffer; cytoskelet

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K pathway in prostate cancer: All resistant roads lead to PI3K

Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

YAP promotes breast cancer metastasis by repressing growth differentiation factor-15

Keywords: ALPP; alkaline phosphatase; AREG; amphiregulin; α-SMA; alpha smooth muscle actin; BIRC5; baculoviral inhibitor of apoptosis repeat-containing 5; ChIP; chromatin immunoprecipitation; CTGF; connective tissue growth factor; DDIT4; DNA-damage inducible trans

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Dual Role of EZH2 in Cutaneous Anaplastic Large Cell Lymphoma: Promoting Tumor Cell Survival and Regulating Tumor Microenvironment

Keywords: CD30+LPD; CD30+ lymphoproliferative disease; CTCL; cutaneous T-cell lymphoma; CXCL10; C-X-C motif chemokine ligand 10; CXCR3; C-X-C motif chemokine receptor 3; EZH2; enhancer of zeste homolog; H3K27me3; histone H3 lysine 27 trimethylation; LCT; large-cell

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Overexpression of OCT4 induced by modulation of histone marks plays crucial role in breast cancer progression

Keywords: CSC; cancer stem cell; ChIP; chromatin immunoprecipitation; DZNeP; deazaneplanocin A hydrochloride; DNMT; DNA methyltransferase; EZH2; enhancer of Zeste homolog 2; HDAC; histone deacetylase; H3K4me3; histone 3 lysine 4 trimethylation; H3K9acS10p; histone

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo

Keywords: PPI; polyphyllin I; CRPC; castration-resistant prostate cancer; EZH2; Zeste homolog 2; DNMT1; DNA methyltransferase 1; HOTAIR; HOX transcript antisense RNA; ADT; androgen deprivation therapy; NF-κB; nuclear factor-kappaB; lncRNA; Long non-coding RNA; DNM

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Aflatoxin B1 induced multiple epigenetic modulators in human epithelial cell lines

Keywords: Aflatoxin B1; DNMTs; HAT; HDACs; Polycomb repressor complex; DNMTs; DNA methyltransferases; HATs; histone acetyltransferases; HDACs; histone deacetylases; PcG; polycomb group proteins; PRC; polycomb repressive complex; EZH2; enhancer of zeste homolog 2; S

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity

Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Clinicopathological significance and prognostic role of EZH2 expression in non-small cell lung cancer

Keywords: Non-small cell lung cancer; EZH2; Clinicopathological significance; Prognosis; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperPrimary myelofibrosis: Older age and high JAK2V617F allele burden are associated with elevated plasma high-sensitivity C-reactive protein levels and a phenotype of progressive disease

Keywords: Myelofibrosis; C-reactive protein; Inflammation; JAK2V617F; MPL; CALR; ASXL1; EZH2; A3669G polymorphism; 46/1 haplotype;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

EZH2-mediated α-actin methylation needs lncRNA TUG1, and promotes the cortex cytoskeleton formation in VSMCs

Keywords: LncRNAs; long non-coding RNAs; TUG1; taurine up-regulated gene 1; VSMCs; vascular smooth muscle cells; SENCR; smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA; Ang II; angiotensin II; PRC2; polycomb repr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Overexpression of the long non-coding RNA SPRY4-IT1 promotes tumor cell proliferation and invasion by activating EZH2 in hepatocellular carcinoma

Keywords: Hepatocellular carcinoma; SPRY4-IT1; Epithelial-mesenchymal transition; EZH2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

miR-98 inhibits hepatocellular carcinoma cell proliferation via targeting EZH2 and suppressing Wnt/β-catenin signaling pathway

Keywords: Hepatocellular carcinoma; miR-98; EZH2; Wnt/β-catenin pathway;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionIncreased expression of EZH2 in Merkel cell carcinoma is associated with disease progression and poorer prognosis

Keywords: Immunohistochemistry; Merkel cell carcinoma; EZH2; Polycomb complex; Disease progression;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

20(S)-Ginsenoside Rh2 suppresses proliferation and migration of hepatocellular carcinoma cells by targeting EZH2 to regulate CDKN2A-2B gene cluster transcription

Keywords: Ginsenoside Rh2 (PubChem CID: 119307); 20(S)-Ginsenoside Rh2; EZH2; CDKN2A-2B gene cluster; Hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome

Keywords: EZH2; H3K27 methyltransferase; Myelodysplastic syndromes;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Split luciferase-based biosensors for characterizing EED binders

Keywords: PRC2; EED; H3K27me3-pocket; Split luciferase; Biosensor; EED[G255D]; EED; embryonic ectoderm development; PRC2; polycomb repressive complex 2; DSF; differential scanning fluorimetry; ITC; isothermal titration calorimetry; EZH2; enhancer of zeste homolog 2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR

Keywords: EZH2; Indoline; Anticancer; Methyltransferases;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Linc00152 promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma

Keywords: ：Hepatocellular carcinoma; Linc00152; HBx; Epithelial-mesenchymal transition; EZH2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis

Keywords: Cre; Cre recombinase; Dnmt1; DNA methyltransferase 1; Dox; doxycycline; DT; diphtheria toxin; DTR; diphtheria toxin receptor; Ezh2; enhancer of zeste homolog 2; Gcg; glucagon; IAP; intracisternal A-particle; Ins; insulin; m-o; month-old; PRC; polycomb rep

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

LSD1 collaborates with EZH2 to regulate expression of interferon-stimulated genes

Keywords: LSD1; EZH2; Histone modification; Interferon pathway; IRF9;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis

Keywords: EZH1; EZH2; Polycomb-Group protein; Histone methylation; Enhancer; Spermatogenesis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchEnhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity

Keywords: Neuroblastoma; EZH2; Histone methyltransferase; Apoptosis; GSK126; EPZ6438;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Menin regulates Inhbb expression through an Akt/Ezh2-mediated H3K27 histone modification

Keywords: ChIP; Chromatin Immuno-Precipitation; Dpc; Day post coitum; MEF; Mouse embryonic fibroblast; Men1; Multiple endocrine neoplasia type1; PanNET; Pancreatic NeuroEndocrine Tumour; PcG; Polycomb Gene; PCR; Polymerase Chain Reaction; PRC; Polycomp Repressing C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleLncRNA SPRY4-IT1 sponges miR-101-3p to promote proliferation and metastasis of bladder cancer cells through up-regulating EZH2

Keywords: SPRY4-IT1; Bladder cancer; miR-101-3p; EZH2; Long noncoding RNA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Mini-reviewNaturally occurring anti-cancer agents targeting EZH2

Keywords: EZH2; Cancer; PRC2; Polycomb proteins; Natural compounds; Chemosensitization;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The histone lysine methyltransferase Ezh2 is required for maintenance of the intestine integrity and for caudal fin regeneration in zebrafish

Keywords: bp; base pair; dpf; days post fertilization; dpa; days post amputation; ezh2; enhancer of zeste homolog 2 (polycomb repressive complex 2 subunit); hpf; hours post fertilization; gcga; glucagon a; ins; insulin; NMD; nonsense-mediated decay; nt; nucleotide;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Drug discovery and therapeutic delivery for the treatment of B and T cell tumors

Keywords: Lymphoma; Leukemia; Multiple myeloma; B cell receptor; Biomaterial; Vaccine; Epigenetic inhibitors; Nanoparticles; EZH2;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

The long non-coding RNA NEAT1 interacted with miR-101 modulates breast cancer growth by targeting EZH2

Keywords: lncRNA; NEAT1; miR-101; Breast cancer; EZH2;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity

Keywords: Pancreatic Cancer; Histone Methyltransferase; Epigenetic Gene Regulation; Oncogene; EZH2; ADM; acinar-to-ductal metaplasia; AP; acute pancreatitis; ChIP; chromatin immunoprecipitation; CP; chronic pancreatitis; CsA; cyclosporine A; DZNep; 3-deazaneplanoci

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

EZH2 regulates spinal neuroinflammation in rats with neuropathic pain

Keywords: EDTA; ethylenediaminetetraacetic acid; EZH2; enhancer of zeste homolog-2; H3K27; histone H3 on K27; H3K27TM; tri-methylated H3K27; MeCP2; methyl-CpG-binding protein 2; PRC2; polycomb complex 2; pSNL; partial sciatic nerve ligation; nociception; cytokine;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver

Keywords: Hotair; LncRNA HOX transcript antisense RNA; HSCs; hepatic stellate cells; PRC2; polycomb repressive complex 2; H3K27me3; histone H3-lysine27; DNMT1; DNA methyltransferase 1; α-SMA; alpha smooth muscle actin; Col1a1; alpha1(1) collagen; NcRNA; non-coding

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Conserved effect of aging on DNA methylation and association with EZH2 polycomb protein in mice and humans

Keywords: MBD-seq; methyl-CpG binding domain protein-enriched sequencing; PRC; polycomb repressive complex; age-DMR; age-dependent differentially methylated regions; mos; months; CF; coupling factor; CGI; CpG island; ChIP-qPCR; chromatin immunoprecipitation quantit

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

WT1 ameliorates podocyte injury via repression of EZH2/β-catenin pathway in diabetic nephropathy

Keywords: BUN; blood urea nitrogen; Ccr; creatinine clearance rate; ChIP; chromatin immunoprecipitation; CTNNB1; β-catenin 1; DAPI; 4,6-diamidino-2-phenylindole; DCFH-DA; 2′, 7′-dichlorodihydrofluorescein diacetate; DMSO; dimethyl sulphoxide; DN; diabetic neph

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Chromatin remodeling gene EZH2 involved in the genetic etiology of autism in Chinese Han population

Keywords: Autism; EZH2; Chromatin remodeling gene; Family-based association test;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays

Keywords: EZH2; Epigenetics; PRC2; Computational drug design; Pharmacophore-based virtual screening

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

In utero exposure to carcinogens: Epigenetics, developmental disruption and consequences in later life

Keywords: 5-mc; 5-methylcytosine; AhR; aryl hydrocarbon receptor; AKT; protein kinase B; BPA; bisphenol A; CNS; central nervous system; CS; cigarette smoke; DBP; dibenzo(α1) pyrene; DES; diethylstilboestrol; DNMT; N-methyltransferase; E2; 17-β-oestradiol; ED; end

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Enhancer of zeste homolog 2 (EZH2) expression in bladder cancer

Keywords: EZH2; Bladder cancer; Urothelial carcinoma in situ; Papillary urothelial carcinoma; Urothelium; Tumor lineage;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Down-regulation of EZH2 expression in myelodysplastic syndromes

Keywords: Myelodysplastic syndromes; EZH2; Histone methylation; Epigenetics;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Selective inhibition of EZH2 by ZLD10A blocks H3K27 methylation and kills mutant lymphoma cells proliferation

Keywords: EZH2; Small molecule; Lymphoma; Anti-tumor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه