Keywords: Multiple sclerosis; Methionine metabolism; Histone methylation; DNA methyltransferases;
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Keywords: Solea senegalensis; Epigenetics; Thermal plasticity; Dnmt; Histone; Growth; CDH; cumulative degree-hours; dnmt; DNA methyltransferases; dph; days post-hatch; EST; expressed sequence tag; H3; histone 3; HPT; Hypothalamic-pituitary-thyroid; IGFs; insulin gr
Keywords: AhR; aryl hydrocarbon receptor; DMR; differentially methylated region; DNMT; DNA methyltransferases; HAT; histone acetyltransferase; HDAC; deacetylation occurs by histone deacetylase; HDM; house dust mite; ILC2; innate lymphoid cells; IM; interstitial mac
Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: BPH; benign prostate hyperplasia; CRD; cysteine-rich domain; DKKs; Dickkopfs; DNMTs; DNA methyltransferases; Fz; Frizzled; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; LC; liver cirrhosis; LRP-5/6; low-density lipoprotein receptor-related protei
Keywords: AD; Alzheimer's Disease; HADACs; histone deacetylases; APP; amyloid precursor protein; SIRT1; sirtuin 1; APOE; apolipoprotein E; PSEN1; presenilin 1; PIN1; peptidyl prolyl isomerase 1; PBMCs; peripheral blood mononuclear cells; DNMTs; DNA methyltransfer
Keywords: AGE; advanced glycation end product; TLR; toll like receptor; FFA; free fatty acid; ROS; reactive oxygen species; c-JNK; c-Jun N-terminal kinase; HMT; histone methyltransferase; HDM; histone demethylase; DNMT; DNA methyltransferases; TET; ten-eleven trans
Keywords: Aza; 5-aza 2 deoxycytidine; TSA; trichostatin A; MeCP2; methyl CpG binding protein 2; SLE; systemic lupus erythematosus; RA; rheumatoid arthritis; DNMTs; DNA methyltransferases; HDACs; histone deacetylases; HAT; histones acetyl transferases; HMT; histone
Keywords: AS-RNA; antisense RNA; BAT; brown adipose tissue; BET; bromodomain and extraterminal; BMI; body mass index; CAD; coronary artery disease; CVD; cardiovascular diseases; DHA; docosahexaenoic acid; DMR; differentially-methylated region; DNMTs; DNA methyltran
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AT; ataxia telangiectasia; BER; base excision repair; BFB; breakage-fusion-bridge; BMDCs; bone marrow-derived cells; BS; Bloom syndrome; CIN; chromosome instability; CNS; central nervous syste
Keywords: AdoMet; S-adenosyl-l-methionine; AMI-1; arginine N-methyltransferase inhibitor-1; AMI-5; arginine(lysine) N-methyltransferase inhibitor-5; DAPI; 4â²,6-diamidino-2-phenylindole; DNMTs; DNA methyltransferases; FDA; Food and Drug Administration; HDACs; hist
Keywords: CCA; cholangiocarcinoma; OS; overall survival; miRNA; microRNA; TSG; tumor suppressor genes; ICC; intrahepatic cholangiocarcinoma; OV; Opisthorchis viverrini; CpG; scytosine guanine dinucleotides; DNMT; DNA methyltransferases; EZH2; zeste homolog 2; RASSF
Keywords: SSc; systemic sclerosis; SRC; scleroderma renal crisis; PAH; pulmonary arterial hypertension; SMR; standardized mortality ratio; DNMTs; DNA methyltransferases; SAM; S-adenosyl-methionine; 5mC; 5-methylcytosine; MBD; methyl-CpG-binding domain; Tet; ten-e
Keywords: AID/APOBEC; activation-induced cytidine deaminase/apolipoprotein B mRNA-editing enzyme complex; BDNF; brain-derived neurotrophic factor; 5caC; 5-carboxylcytosine; CBP; CREB binding protein; CREB; cAMP response binding protein; DNMT; DNA methyltransferases
Keywords: Medulloblastoma; Receptor Tyrosine Kinases; DNA methyltransferases; Histone deacetylases;
Keywords: 5caC; 5-carboxylcytosine; 5fC; 5-formylcytosine; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; CAR; constitutive androstane receptor; CGI; CpG island; CpG; cytosinephosophate-guanine; CNV; copy number variation; DEN; diethylnitrosamine; DNMT; DNA
Keywords: DNA methylation; Okadaic acid; Morphine addiction; Conditioned place preference; Hippocampus; Prelimbic cortex; 5-aza; 5-aza-2-deoxycytidine; DNMTs; DNA methyltransferases; PL; prelimbic cortex; mCPP; morphine-induced conditioned place preference; PP; pro
Keywords: aDMR; age-associated differentially methylation regions; DNMTs; DNA methyltransferases; ROS; reactive oxygen species; CR; caloric restriction; DR; dietary restriction; ADF; alternate-day fasting; PBMCs; peripheral blood mononuclear cells; AdoMet; S-adenos
Keywords: ECMs; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β1; transforming growth factor-β1; Ang-II; angiotension II; DNMTs; DNA methyltransferases; 5-Aza-dC; 5-Aza-2â²-deoxycytidine; EZH2; Enhancer of zeste homolog 2; HDAC; histone deacetylases;
Antidepressant administration modulates stress-induced DNA methylation and DNA methyltransferase expression in rat prefrontal cortex and hippocampus
Keywords: DNMTs; DNA methyltransferases; CNS; central nervous system; TST; tail suspension test; FST; forced swimming test; dHPC; dorsal hippocampus; vHPC; ventral hippocampus; PFC; prefrontal cortex; LH; learned helplessness; DNA methylation; DNMT; Antidepressant;
Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications
Keywords: Mouse embryonic stem cells; Endoderm hepatic specification; Endothelial cells; VEGFR2; Epigenetic modifications; ESC; human embryonic stem cell; EB; embryoid body; AL End; mouse ESC-derived endoderm cells cultured alone; CC End; mouse ESC-derived endoderm
Emerging role of lncRNAs in systemic lupus erythematosus
Keywords: AR5; accessible region 5; C3; complement 3; CNS3; conserved noncoding sequence 3; DBD; DNA-binding domain; DCs; dendritic cells; DDX5; RNA helicase DEAD-box protein 5; DHFR; dihydrofolate reductase; DNMTs; DNA methyltransferases; ERα; estrogen receptor Î
Insulin-like peptides and DNA/tRNA methyltransferases are involved in the nutritional regulation of female reproduction in Nilaparvata lugens (Stål)
Keywords: bp; base pair; cDNA; DNA complementary to RNA; dNTP; deoxyribonucleoside triphosphate; kb; kilobase; kDa; kilodalton; ORF; open reading frame; UTR; untranslated region; RACE; rapid amplification of cDNA ends; qPCR; quantitative real time PCR; AAs; amino a
Cortex and hippocampus DNA epigenetic response to a long-term arsenic exposure via drinking water
Keywords: Arsenic; DNA epigenetics; Oxidative stress; DNA methyltransferases; Ten-eleven translocations;
Cocaine-induced epigenetic DNA modification in mouse addiction-specific and non-specific tissues
Keywords: Cocaine; Nucleus accumbens; Cerebellum; Peripheral blood cells; DNA methyltransferases; Ten-eleven translocation enzymes; Mouse;
The role of DNA methylation in coronary artery disease
Keywords: (5Aza); 5-aza-2â²-deoxycytidine; (ACAT1); acetyl-CoA acetyltransferase 1; (ACS); acute coronary syndrome; (ApoE); Apolipoprotein E; (ABCA1); ATP-binding cassette A1; (BDNF); brain-derived neurotrophic factor; (CNKI); China National Knowledge Infrastructu
Low-functional programming of the CREB/BDNF/TrkB pathway mediates cognitive impairment in male offspring after prenatal dexamethasone exposure
Keywords: Akt; protein kinase B; Bax; Bcl-2 associated x protein; Bcl-2; B-cell lymphoma 2; BDNF; brain-derived neurotrophic factor; CaMKII; calmodulin-dependent protein kinase II; Caspase-3; cysteine aspartic protease 3; CDK2; cyclin-dependent kinase-2; CDC42; cel
Evaluation of leptin and MMP2 genes methylation in childhood obesity
Keywords: AUC; Area under the curve; BMI; Body Mass Index; DNMTs; DNA methyltransferases; ELISA; Enzyme-linked immunosorbent assay; MMP2; Matrix metalloproteinase-2; NO; Nitric oxide; PGE2; Prostaglandin E2; qMS-PCR; Quantitative methylation specific real-time PCR;
Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation
Keywords: SAM; S-adenosyl methonine; SAH; S-adenosyl homocystene; MS-HRM; methylation-sensitive high-resolution melting; DNMTs; DNA methyltransferases; WG; weanling group; YG; young group; AG; adult group; FD; folate deficiency; PF; physiological folate; FS; folate
Genome-wide identification, evolution of DNA methyltransferases and their expression during gonadal development in Nile tilapia
Keywords: DNA methyltransferases; Evolution; Tilapia; Temporal and spatial expression profiles; Gonad;
A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases
Keywords: BER; base excision repair; 5caC; 5-carboxylcytosine; CPDB; ConsensuspathDB; DEGs; differentially expressed genes; DhMRs; differentially hydroxyl-methylated regions; DNMTs; DNA methyltransferases; 5fU; 5-formyluracil; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-
DACT2 Epigenetic Stimulator Exerts Dual Efficacy for Colorectal Cancer Prevention and Treatment
Keywords: 5aza; thioguanine and 5-azacytidine; AOM; azoxymethane; CRC; clinical colorectal cancer; DACT2; dishevelled binding antagonist of beta catenin 2; DAI; disease activity index; DNMTs; DNA methyltransferases; DSS; dextran sodium sulfate; HDACs; histone deace
TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress
Keywords: ROS; reactive oxygen species; MMP; mitochondrial membrane potential; TRPM2; transient receptor potential cation channel subfamily M member 2; H2O2; hydrogen peroxide; NHMs; Normal human melanocytes; NAC; N-acety-L-cysteine; Ru360; Ruthenium 360; 5-aza-dC;
Aflatoxin B1 induced multiple epigenetic modulators in human epithelial cell lines
Keywords: Aflatoxin B1; DNMTs; HAT; HDACs; Polycomb repressor complex; DNMTs; DNA methyltransferases; HATs; histone acetyltransferases; HDACs; histone deacetylases; PcG; polycomb group proteins; PRC; polycomb repressive complex; EZH2; enhancer of zeste homolog 2; S
Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons
Keywords: Actb; β-actin; Aβ; amyloid beta; AD; Alzheimer's disease; ANOVA; analysis of variance; ASD; autism spectrum disorder; BP-3; benzophenone-3; BPA; bisphenol A; BPs; benzophenones; BSA; bovine serum albumin; Casp3; caspase-3; CNS; central nervous system; D
Impact of obesity and overweight on DNA stability: Few facts and many hypotheses
Keywords: AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL
Anti-oxidative and anti-inflammatory benefits of the ribonucleoside analogue 5-azacitidine in mice with acetaminophen-induced toxic hepatitis
Keywords: Acetaminophen; Toxic hepatitis; 5-Azacitidine; DNA methyltransferases; Methylation;
Detection and discrimination of maintenance and de novo CpG methylation events using MethylBreak
Keywords: DNA methyltransferases; Methylation-sensitive endonucleases; Molecular beacon; MethylBreak; Maintenance methylation; de novo methylation;
TGF-β-mediated repression of MST1 by DNMT1 promotes glioma malignancy
Keywords: WHO; World Health Organization; MST1; Mammalian Sterile 20 Like Kinase 1; NES; nuclear export sites; DNMTs; DNA methyltransferases; Glioma; MST1; DNMT1;
Structure and expression of dna methyltransferase genes from apomictic and sexual Boechera species
Keywords: DNA methylation; DNA methyltransferases; Boechera; Apomixis; Seed development;
DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8
Keywords: acute kidney injury; cisplatin; DNA methylation; DNA methyltransferases; nephrotoxicity;
Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition
Keywords: Inorganic arsenic; DNA methylation; Infinium MethylationEPIC BeadChip; EMT; Epigenetics; NT; nontreated HeLa cells; iAsT; 0.5 μM sodium arsenite treated HeLa cells; iAs-rev; reverse treated cells; EMT; epithelial-to-mesenchymal transition; DMR; Differen
Integrative analysis of DNA methylation and mRNA expression during differentiation of umbilical cord blood derived mononuclear cells to endothelial cells
Keywords: UCB-MNC; umbilical cord blood derived mononuclear cell; OEC; outgrowth endothelial cell; HSC; hematopoietic stem cell; ESC; embryonic stem cell; MeDIP; methylated DNA immunoprecipitation; DNMTases; DNA methyltransferases; TETs; ten-eleven translocation; D
Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway
Keywords: SETDB1; set domain, bifurcated 1; H3K9; histone H3 lysine 9; SSCs; spermatogonial stem cells; GDNF; glial cell line-derived neurotrophic factor; SFK; Src family kinase; PI3K; phosphatidylinositol 3-kinase; ESCs; embryo stem cells; DMEM/F12; Modified Eagle
Insights into inner ear-specific gene regulation: Epigenetics and non-coding RNAs in inner ear development and regeneration
Keywords: bps; base pairs; DHS; DNase Hypersensitive sites; TFBS; transcription factor binding sites; PTMs; post-translational modifications; HDACs; histone deacetylases; H3K4me3; histone 3 lysine 4 tri-methylation; H3K27me3; histone 3 lysine 27 tri-methylation; Ch
In vivo and in silico studies to identify mechanisms associated with Nurr1 modulation following early life exposure to permethrin in rats
Keywords: 3-PBA; 3-phenoxybenzoic acid; BBB; blood-brain barrier; DNMTs; DNA methyltransferases; EDTA; ethylenediaminetetraacetic acid; LBD; Ligand Binding Domain; MSP; Methylation-Specific PCR; NOAEL; No Observed Adverse Effect Level; NuIP; Nurr1-interacting pro
DNA methyltransferase 1 rs16999593 genetic polymorphism decreases risk in patients with transposition of great arteries
Keywords: TGA; Transposition of the great arteries; SNPs; single nucleotide polymorphisms; dTGA; Dextro-transposition of the great arteries; DNMT1; DNA methyctransferase 1; ASD; atrial septal defect; VSD; ventricular septal defect; PDA; patent ductus arteriosus; HW
Abnormal DNA methylation in the lumbar spinal cord following chronic constriction injury in rats
Keywords: Neuropathic pain; Chronic constriction injury; DNA methyltransferases; Methyl-DNA binding domain proteins; Glutamate decarboxylase 67; Glutamate decarboxylase 1 promoter;
Flexible double-headed cytosine-linked 2′-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases
Keywords: Nucleosides; Nucleotides; Pyrimidines; DNA methyltransferases; DNA polymerases
Acetylation of histones in neocortex and hippocampus of rats exposed to different modes of hypobaric hypoxia: Implications for brain hypoxic injury and tolerance
Keywords: SH; severe hypoxia; HDACs; histone deacetylases; HATs; histone acetyltransferases; DNMTs; DNA methyltransferases; GR; glucocorticoid receptor; MR; mineralocorticoid receptor; pan-ac; pan-acetyl proteins; H3K24ac; acetylated histone H3 (Lys24); Acetylation