Keywords: دیسلوکپیپین; Cellular viability; Creatine; Glutamate; Hydrogen peroxide; Nitric oxide; MTT; 3-(4,5-dimethylthiazol-2-yl-diphenyltetrazolium bromide); DCF; dichlorofluorescein; MK-801; Dizocilpine; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; H2O2
مقالات ISI دیسلوکپیپین (ترجمه نشده)
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Non-competitive antagonists of NMDA and AMPA receptors decrease seizure-induced c-fos protein expression in the cerebellum and protect against seizure symptoms in adult rats
Keywords: دیسلوکپیپین; AOI; area of interest; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA; analysis of variance; 4-AP; 4-aminopyridine; c-fosIR; c-fos immunoreactive; DAB; 3, 3â²-diaminobenzidine tetrahydrochloride; DMSO; dimethyl sulfoxide; EDTA; ethyle
Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies
Keywords: دیسلوکپیپین; Ketamine; microRNA; Prefrontal cortex; Small interfering RNA; RNA interference; 5-HT; serotonin; 5-HT1A receptor; serotonin 1A receptor; A1; adenosine A1 receptor; AchE; acetylcholinesterase; AGO; argonaute; Akt-mTOR; protein kinase B/Akt- mammalian targe
Activation of the sigma receptor 1 modulates AMPA receptor-mediated light-evoked excitatory postsynaptic currents in rat retinal ganglion cells
Keywords: دیسلوکپیپین; AMPAR; a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor; BiP; binding immunoglobulin protein; BisIV; bisindolylmaleimide IV; [Ca2+]i; intracellular calcium concentration; DMSO; dimethyl sulfoxide; E-EPSC; electrically evoked excitatory posts
Research reportMK-801 and memantine act differently on short-term memory tested with different time-intervals in the Morris water maze test
Keywords: دیسلوکپیپین; Short-term memory; Spatial working memory; Memantine; Dizocilpine; Morris water maze;
NMDA receptors are involved in the antidepressant-like effects of capsaicin following amphetamine withdrawal in male mice
Keywords: دیسلوکپیپین; AW; amphetamine withdrawal; FST; forced swimming test; MK-801; dizocilpine; NMDA; N-Methyl-d-aspartate; OFT; open-field test; TRPV1; transient receptor potential cation channel, subfamily V, member 1; amphetamine withdrawal; depression; TRPV1; NMDA recept
NMDA and dopamine D1 receptors within NAc-shell regulate IEG proteins expression in reward circuit during cocaine memory reconsolidation
Keywords: دیسلوکپیپین; CPP; conditioned place preference; IEG; immediate early gene; IL; infralimbic cortex; MK 801; dizocilpine; mPFC; medial prefrontal cortex; NAc; nucleus accumbens; NMDA; N-methyl-d-aspartate; PBS; phosphate-buffered saline; PKA; protein kinase A; SuM; supr
Continuous exposure to dizocilpine facilitates the acquisition and escalation of cocaine consumption in male Sprague-Dawley rats
Keywords: دیسلوکپیپین; Cocaine self-administration; Escalation; Acquisition; N-methyl-d-aspartate (NMDA) receptor (NMDAR); Dizocilpine;
Inhibition of NMDAR Reduces Bladder Hypertrophy and Improves Bladder Function in Cyclophosphamide Induced Cystitis
Keywords: دیسلوکپیپین; urinary bladder; overactive; receptors; N-methyl-D-aspartate; collagen; cystitis; interstitial; hypertrophy; Akt; protein kinase B; BOO; bladder outlet obstruction; CCh; carbachol; CYP; cyclophosphamide; D-AP5; D-2-amino-5-phosphonopentanoate; MK-801; diz
Effects of ApoE on intracellular calcium levels and apoptosis of neurons after mechanical injury
Keywords: دیسلوکپیپین; ApoE; apolipoprotein e; BBB; blood-brain barrier; EGTA; ethylene glycol tetraacetic acid; FCM; flow cytometry; FITC; fluorescein isothiocyanate; MK801; dizocilpine; NMDAR; N-methyl-d-aspartate receptor; PBS; phosphate-buffered saline; PI; propidium iodi
Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin-dopamine activity modulator
Keywords: دیسلوکپیپین; Antipsychotic drug; Brexpiprazole; Dizocilpine; Social recognition; 5-HT1A receptor;
In vivo and in vitro ketamine exposure exhibits a dose-dependent induction of activity-dependent neuroprotective protein in rat neurons
Keywords: دیسلوکپیپین; AASS; antibiotic antimycotic solution stabilized; AC3; activated caspase 3; ADNF; activity-dependent neurotrophic factor; ADNP; activity-dependent neuroprotective protein; ASD; autism spectrum disorder; BCA; bicinchoninic acid; DAPI; 4â²,6-diamidino-2-ph
Presynaptic NMDA receptors: Roles and rules
Keywords: دیسلوکپیپین; APV; 2-amino-5-phosphonopentanoic acid; BDNF; brain-derived neurotrophic factor; EPSC; excitatory postsynaptic current; mIPSC; miniature inhibitory postsynaptic current; MK-801; dizocilpine; MLI; molecular layer interneuron; NMDARs; NMDA receptors; nNOS;
Prenatal administration of lipopolysaccharide induces sex-dependent changes in glutamic acid decarboxylase and parvalbumin in the adult rat brain
Keywords: دیسلوکپیپین; ANOVA; analysis of variance; DG; dentate gyrus; ER; estrogen receptor; GABA; gamma-aminobutyric acid; GAD67; glutamate decarboxylase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; IL-1β; interleukin 1β; IL-2; interleukin 2; IL-6; interleukin 6; IOD;
Orphenadrine-induced convulsive status epilepticus in rats responds to the NMDA antagonist dizocilpine
Keywords: دیسلوکپیپین; Orphenadrine; Dizocilpine; Refractory status epilepticus model; Rats
Continuous exposure to dizocilpine facilitates escalation of cocaine consumption in male Sprague-Dawley rats
Keywords: دیسلوکپیپین; Escalation; Self-administration; Cocaine; NMDA; Dizocilpine;
Decreasing nicotinic receptor activity and the spatial learning impairment caused by the NMDA glutamate antagonist dizocilpine in rats
Keywords: دیسلوکپیپین; Nicotinic; Antagonist; Learning; α4β2; α7; Dizocilpine;
Research reportmGluR3 knockout mice show a working memory defect and an enhanced response to MK-801 in the T- and Y-maze cognitive tests
Keywords: دیسلوکپیپین; ANOVA; analyses of variance; GRM3; mGluR3 gene; KO; knockout; mGluR; metabotropic glutamate receptor; MK-801; dizocilpine; NMDA; N-methyl-d-aspartate; WT; wildtype; mGlu3 receptor; Mouse; Working memory; Side bias; Left-right asymmetry; Dizocilpine;
Research reportImpairment of the anterior thalamic head direction cell network following administration of the NMDA antagonist MK-801
Keywords: دیسلوکپیپین; Navigation; Spatial orientation; Place cells; Dizocilpine; N-methyl-D-aspartate; Rat;
Frequency-specific response facilitation of supra and infragranular barrel cortical neurons depends on NMDA receptor activation in rats
Keywords: دیسلوکپیپین; Ach; acetylcholine; APV; (2R)-amino-5-phosphonovaleric acid, (2R)-amino-5-phosphonopentanoate; LTP; long-term potentiation; MK801; dizocilpine; NMDA; N-methyl-d-aspartate receptor; PSTH; peristimulus time histogram; RF; receptive field; SEM; standard erro
Visuospatial working memory is impaired in an animal model of schizophrenia induced by acute MK-801: An effect of pretraining
Keywords: دیسلوکپیپین; Allothetic place avoidance alternation; Working memory; Dizocilpine; Navigation; Schizophrenia;
Behavioural consequences of IVC cages on male and female C57BL/6J mice
Keywords: دیسلوکپیپین; ANOVA; analysis of variance; CS; conditioned stimulus; EPM; elevated plus maze; FC; fear conditioning; FILTER; filter-top cages; IVC; individually ventilated cage; MK-801; dizocilpine; NeuRA; Neuroscience Research Australia; NMDA; N-methyl-d-aspartate; OF
Invited reviewLong-lasting changes in hippocampal synaptic plasticity and cognition in an animal model of NMDA receptor dysfunction in psychosis
Keywords: دیسلوکپیپین; Schizophrenia; Psychosis; Animal model; MK801; LTP; Hippocampus; Dizocilpine;
Rhythmic theta and delta activity of cortical and hippocampal neuronal networks in genetically or pharmacologically induced N-methyl-d-aspartate receptor hypofunction under urethane anesthesia
Keywords: دیسلوکپیپین; AMPAR; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ANOVA; analysis of variance; CA1; hippocampal region CA1; EEG; Electroencephalogram; Grin1; Grin1tm1Bhk mouse model expressing reduced NR1 NMDAR subunit expression; IV; intravenous;
Two learning tasks provide evidence for disrupted behavioural flexibility in an animal model of schizophrenia-like behaviour induced by acute MK-801: A dose–response study
Keywords: دیسلوکپیپین; Spatial learning; Memory; Flexibility; Reversal; Rat; Dizocilpine; Maze
Lesions of the rat entopeduncular nucleus further deteriorate N-methyl-d-aspartate receptor antagonist-induced deficient prepulse inhibition
Keywords: دیسلوکپیپین; Prepulse inhibition; Startle; Locomotor activity; Globus pallidus internus; Basal ganglia; Entopeduncular nucleus; Dizocilpine
Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits
Keywords: دیسلوکپیپین; Startle; PPI; Prepulse inhibition; Amphetamine; Dizocilpine; MK-801; Mirtazapine; Dopamine; Glutamate; Norepinepherine; Serotonin;
Research ReportNerve growth factor and brain-derived neurotrophic factor but not granulocyte colony-stimulating factor, nimodipine and dizocilpine, require ATP for neuroprotective activity after oxygen-glucose deprivation of primary neurons
Keywords: دیسلوکپیپین; AP; alkaline phosphatase; BDNF; brain-derived neurothrophic factor; CD; circular dichroism; DMSO; dimethyl sulfoxide; Dizo; dizocilpine; DMEM; Dulbecco's modified Eagle's medium; FGF2; fibroblast growth factor 2; GCSF; granulocyte colony-stimulating facto
The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion
Keywords: دیسلوکپیپین; APD, antipsychotic drug; NT, neurotensin; PPI, prepulse inhibition of acoustic startle response; NAcc, nucleus accumbens; NTR, NT receptor; VTA, ventral tegmental areaPrepulse inhibition; Locomotion; d-amphetamine; Apomorphine; Dizocilpine; c-fos; Neurote
The antidepressant phenelzine enhances memory in the double Y-maze and increases GABA levels in the hippocampus and frontal cortex of rats
Keywords: دیسلوکپیپین; Alanine; Behavior; Cognitive; Dizocilpine; Glutamine; HPLC;
Lamotrigine blocks repeated high-dose methamphetamine-induced behavioral sensitization to dizocilpine (MK-801), but not methamphetamine in rats
Keywords: دیسلوکپیپین; Cross-sensitization; Lamotrigine; Methamphetamine; Dizocilpine; Schizophrenia
Role of endocannabinoid and glutamatergic systems in DOI-induced head-twitch response in mice
Keywords: دیسلوکپیپین; ADHD; Attention-deficit/hyperactivity disorder; AM281; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; AM404; N-(4-hydroxyphenyl)arachidonylamide; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; Anan
Effects of dizocilpine (MK801) on olfactory span in rats
Keywords: دیسلوکپیپین; Working memory; Olfactory span; NMDA antagonist; MK801; Dizocilpine
Behavioral performance altering effects of MK-801 in zebrafish (Danio rerio)
Keywords: دیسلوکپیپین; Dizocilpine; MK-801; NMDA-R; Motivation; Motor function; Perception; Zebrafish
Sensorimotor gating and vigilance-dependent choice accuracy: A within-subject correlative analysis in wild-type C57BL/6 mice
Keywords: دیسلوکپیپین; Attention; Prepulse inhibition; Mice; Dizocilpine; Scopolamine; Schizophrenia;
MK-801 increases the baseline level of anxiety in mice introduced to a spatial memory task without prior habituation
Keywords: دیسلوکپیپین; Dizocilpine; NMDA; Open-space; Maze; Spatial navigation; Habituation; Anxiety; Consolidation
Differential effects of histamine H3 receptor inverse agonist thioperamide, given alone or in combination with the N-methyl-d-aspartate receptor antagonist dizocilpine, on reconsolidation and consolidation of a contextual fear memory in mice
Keywords: دیسلوکپیپین; consolidation; reconsolidation; thioperamide; dizocilpine; histamine H3 receptor; NMDA receptor; ANOVA; analyses of variance; NMDA; N-methyl-d-aspartate; US; unconditioned stimulus;
Acute nicotine and phencyclidine increase locomotor activity of the guinea pig with attenuated potencies relative to their effects on rat or mouse
Keywords: دیسلوکپیپین; Nicotine; Phencyclidine; MK-801; Dizocilpine; Locomotor activity; Guinea pig
Sensorimotor gating in neurotensin-1 receptor null mice
Keywords: دیسلوکپیپین; Schizophrenia; Neurotensin; Animal model; PD149163; Amphetamine; Dizocilpine
Differential effect of glutamate receptor blockade on dendritic outgrowth in chicken lumbar motoneurons
Keywords: دیسلوکپیپین; Motoneuron; Dendritic morphology; Glutamate receptor; Development; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; E; embryonic day; MK-801; dizocilpine;
NMDAR blockade-induced neonatal brain injury: Reversal by the calcium channel agonist BayK 8644
Keywords: دیسلوکپیپین; Rat; Postnatal; Apoptosis; Set point hypothesis; MK801; Dizocilpine
MK801-induced activated caspase-3 exhibits selective co-localization with GAD67
Keywords: دیسلوکپیپین; Rat; Postnatal; Apoptosis; MK801; Dizocilpine; Synapse; Calcium;
Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats
Keywords: دیسلوکپیپین; Sustained attention; Visual signal detection task; Ritalin®; MK-801; Dizocilpine; Scopolamine; Mecamylamine; Cognition
Deficits in adult prefrontal cortex neurons and behavior following early post-natal NMDA antagonist treatment
Keywords: دیسلوکپیپین; Dizocilpine; Impulsivity; Schizophrenia; Prefrontal cortex; Parvalbumin interneurons; Pyramidal neurons; Anxiety
Neurodegeneration and prolonged immediate early gene expression throughout cortical areas of the rat brain following acute administration of dizocilpine
Keywords: دیسلوکپیپین; Egr-1; FosB; MK-801; neurodegeneration; retrosplenial cortex; somatosensory cortex; A-Cu-Ag; amino-cupric-silver; ENT; entorhinal cortex; FJB; fluoro-jade B; IEGs; immediate early genes; MK801; dizocilpine; NHS; normal horse serum; NMDA-A; N-methy
The putative antipsychotic alstonine reverses social interaction withdrawal in mice
Keywords: دیسلوکپیپین; MK801; dizocilpine; NMDA; N-methyl-d-aspartate; PCP; phencyclidine.; Alstonine; Antipsychotics; MK801-induced social withdrawal; Negative symptoms; Social interaction;
A pharmacological MRI assessment of dizocilpine (MK-801) in the 3-nitroproprionic acid-lesioned rat
Keywords: دیسلوکپیپین; MK-801; Dizocilpine; Neuroprotection; phMRI; MRI; 3-Nitroproprionic acid; Striatum; Huntington's disease; Schizophrenia; NMDA-receptor; Psychomimetic;
Antioxidants attenuate MK-801-induced cortical neurotoxicity in the rat
Keywords: دیسلوکپیپین; Cerebral blood flow; Dizocilpine; Free radicals; Oxidative stress; Spin traps; Vacuolation;
Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory
Keywords: دیسلوکپیپین; psychostimulants; GluR2; NR1; NR2A; astrogliosis; AMPH; amphetamine; CA1; regio superior cornu ammonis; CA3; regio inferior cornu ammonis; DA; dopamine; ED; escalating dose/s; F-J C; Fluoro-Jade C; GFAP; glial fibrillary acidic protein; Glu; glutamate; LT
Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response
Keywords: دیسلوکپیپین; Dizocilpine; MK-801; Nicotine; Clozapine; Pre-pulse inhibition; PPI; Tactile startle;