
Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy
Keywords: cAMP; cyclic adenosine monophosphate; CHO; chinese hamster ovary cell line; CRTh2; chemoattractant receptor-homologous molecule expressed on T-helper cells; DK-PGD2; 13-14-dihydro-15-keto-PGD2; GDP; guanosine diphosphate; GPCR; G protein-coupled receptor;