دانلود مقالات ISI درباره DN، غالب منفی است + ترجمه فارسی

Photo-enhancement of macrophage phagocytic activity via Rac1-mediated signaling pathway: Implications for bacterial infection

Keywords: DN، غالب منفی است; CA, constitutively activated; CFP, cyan fluorescent protein; DN, dominant negative; FRET, fluorescence resonance energy transfer; FCS, fetal calf serum; FITC, fluorescein isothiocyanate; GEF, guanine nucleiotde-exchange factor; GST, glutathione-S-transfer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

p38α regulates SERCA2a function

Keywords: DN، غالب منفی است; Phospholamban; SERCA2a; p38; Cardiac contractilityAMVM, adult mouse ventricular myocyte; ARVM, adult rat ventricular myocyte; dn, dominant negative; ET-1, endothelin-1; GRK, G protein coupled receptor kinase; I-1, inhibitor-1; MAPK, mitogen-activated prot

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1

Keywords: DN، غالب منفی است; BAF, Brg1 Brm associated factors; Brg1, Brahma-related gene 1; Brm, Brahma; CC, Coiled-coil; CDC42, Cell division control protein 42 homolog; DN, Dominant Negative; E, embryonic; EGFP, enhanced green fluorescent protein; F-BAR, FCH-Bin/Amphiphysin/Rvs; FC

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

FcγRI is required for TGFβ2-treated macrophage-induced tolerance

Keywords: DN، غالب منفی است; ACAID, anterior chamber-associated immune deviation; ANOVA, analysis of variance; APC, antigen presenting cells; CFA, complete Freund's adjuvant; DN, dominant negative; DTH, delayed type hypersensitivity; i.v., intravenous; LPS, lipopolysaccharide; Mϕ, ma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Lymphocyte–stromal cell interaction induces IL-7 expression by interferon regulatory factors

Keywords: DN، غالب منفی است; DN, dominant negative; IRF, interferon regulatory factor; ISRE, interferon-stimulated response element; RANK, receptor activator of nuclear factor-κB; shRNA, short hairpin RNA; TLR, toll-like receptorCytokine; Cell adhesion; Transcription factor; Interfer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Estrogen facilitates osteoblast differentiation by upregulating bone morphogenetic protein-4 signaling

Keywords: DN، غالب منفی است; ALK, activin receptor-like kinase; ALP, alkaline phosphatase; ActRІІ, activin type-ІІ receptor; BMP, bone morphogenetic protein; BMPRІІ, BMP type-ІІ receptor; DN, dominant negative; E2, 17β-estradiol; E2-BSA, BSA-conjugated E2; ER, estrogen receptor; Runx

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies

Keywords: DN، غالب منفی است; ALS, amyotrophic lateral sclerosis; ANOVA, analysis of variance; ATF3, activating transcription factor 3; AUC, area under the curve; DN, dominant negative; DRG, dorsal root ganglia; GDNF, glial cell-derived neurotrophic factor; PBS, phosphate-buffered sal

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Bacillus thuringiensis Cry and Cyt mutants useful to counter toxin action in specific environments and to overcome insect resistance in the field

Keywords: DN، غالب منفی است; Bt, Bacillus thuringiensis; APN, aminopeptidase; ALP, alkaline phosphatase; DN, dominant negative; CR, cadherin repeat; TM, transmembrane domain; MPED, membrane proximal ectodomainBacillus thuringiensis; Cry toxin; Cyt toxin; Dominant negative mutant; Ant

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1, 2/Stat6 signal transduction pathway: Implication for atopic dermatitis

Keywords: DN، غالب منفی است; AD, atopic dermatitis; DN, dominant negative; FBS, fetal bovine serum; Jak, Janus kinase; Stat, signal transducer and activator of transcription; TBS, Tris-buffered saline; Tg, transgenicIL-4; CCL26; Gene regulation; Atopic dermatitis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Analysis of the role of p38 MAP kinase in epidermal growth factor-induced JB6 Cl41 cell transformation by cDNA array

Keywords: DN، غالب منفی است; p38 MAPK, p38 mitogen-activated protein kinase; DN, dominant negative; EGF, epidermal growth factor; STAT1, signal transducer and activator of transcription 1; ATF-2, activating transcription factor 2; ERK, extracellular signal-regulated kinase; JNK, c-Ju

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2

Keywords: DN، غالب منفی است; LPS, lipopolysaccharide; SPT, serine palmitoyltransferase; NFκB, nuclear factor kappa B; ChIP, chromatin immunoprecipitation; SM, sphingomyelin; SMase, sphingomyelinase; CAD, coronary artery disease; JNK, c-Jun amino-terminal kinase; dn, dominant negative

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Rapid tip growth: Insights from pollen tubes

Keywords: DN، غالب منفی است; CA, constitutively active; CNGC, cyclic nucleotide-gated channel; CRIB, Cdc42/Rac-interactive binding; DN, dominant negative; ER, endoplasmic reticulum; F-actin, actin filaments; FH3, formin 3; FH5, formin 5; FRAP, fluorescence recovery after photobleachi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε

Keywords: DN، غالب منفی است; PKC, protein kinase C; ADAM, A Disintegrin and Metalloprotease; PDBu, Phorbol-12-13-dibutyrate; PAGE, polyacrylamide gel electrophoresis; ECL, enhanced chemiluminescence; HEK, human embryonic kidney; DN, dominant negative; CA, constitutively active; RD, r

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma

Keywords: DN، غالب منفی است; CA, constitutively active; CML, chronic myelogenous leukemia; DMSO, dimethyl sulfoxide; DN, dominant negative; ERK, extracellular signal-regulated kinase; FITC, fluorescein isothiocyanate; GSH, glutathione; HCC, hepatocellular carcinoma; IκB, nuclear fact

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Cyclic adenosine monophosphate induces plasminogen activator inhibitor-1 expression in human mast cells

Keywords: DN، غالب منفی است; AC, adenylate cyclase; AHR, airway hyperresponsiveness; cAMP, cyclic adenosine monophosphate; CRE, cAMP-response element; CREB, CRE-binding protein, db-cAMP, dibutyryl cAMP; db-cAMP, dibutyryl cAMP; DDA, 2′,5′-dideoxyadenosine; DN, dominant negative; EMSA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin

Keywords: DN، غالب منفی است; Andro, andrographolide; DAPI, 4,6-diamidino-2-phenylindole; DMEM, Dulbecco's modified Eagle's medium; DMSO, dimethyl sulfoxide; DN, dominant negative; FBS, fetal bovine serum; IFN, interferon; IL, interleukin; JAK, Janus kinase; MTT, 3(4,5-dimethylthiazol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Trafficking-deficient long QT syndrome mutation KCNQ1-T587M confers severe clinical phenotype by impairment of KCNH2 membrane localization: Evidence for clinically significant IKr-IKs α-subunit interaction

Keywords: DN، غالب منفی است; Long QT syndrome; KCNQ1; KCNH2; Torsades de pointes; Sudden cardiac deathAU, arbitrary units; CHO, Chinese hamster ovary; dn, dominant negative; ER, endoplasmic reticulum; E1, KCNE1; HEK, human embryonic kidney; H2, KCNH2; LQTS, long QT syndrome; OD, opti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Comparative proteome analysis to explore p53 pathway disruption in head and neck carcinogenesis

Keywords: DN، غالب منفی است; dn, dominant negative; FDR, false discovery rates; FFPE, formalin-fixed paraffin embedded; HNSCC, head and neck squamous cell carcinoma; HPV, human papilloma virus; tsLT, temperature-sensitive allele of SV40 large T antigen gene; IHC, immunohistochemistry

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5

Keywords: DN، غالب منفی است; CDK5, cyclin-dependent kinase 5; dn, dominant negative; PCR, polymerase chain reactionp35; E-cadherin; CDK5; Lysosomal degradation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibition of the ERK phosphorylation plays a role in terbinafine-induced p21 up-regulation and DNA synthesis inhibition in human vascular endothelial cells

Keywords: DN، غالب منفی است; CDK, cyclin-dependent kinase; DEPC, diethyl-pyrocarbonate; DMSO, dimethylsulfoxide; DN, dominant negative; DTT, dithiothreitol; ECL, enhanced chemiluminescence; ECs, endothelial cells; ECGS, endothelial cell growth supplement; ERK, extracellular signal-re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor

Keywords: DN، غالب منفی است; CA, constitutively active; DN, dominant negative; EMT, epithelial–mesenchymal transition; LCM, low-Ca2+ medium; MLC, myosin light chain; MRTF, myocardin-related transcription factor; PAK, p21-activated kinase; PBD, p21 binding domain; ROK, Rho kinase; SFM

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Differential regulation of IKKα-mediated activation of IRF3/7 by NIK

Keywords: DN، غالب منفی است; AP-1, activating protein-1; BHK21 cells, baby hamster kidney 21 cells; BMDCs, bone marrow-derived dendritic cells; CD40, cluster of differentiation 40; CpG-DNA, CpG-oligodeoxynucleotide; DN, dominant negative; HEK293 cells, human embryonic kidney cell lin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes

Keywords: DN، غالب منفی است; Adip., primary human adipocyte; da, dominant active; dn, dominant negative; FPP, farnesyl pyrophosphate; GGPP, geranylgeranyl pyrophosphate; IκB, inhibitor of NFκB; MAPK, mitogen-activated protein kinase; MEKK-1, mitogen-activated protein kinase kinase ki

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Oncostatin M induces growth arrest of skeletal muscle cells in G1 phase by regulating cyclin D1 protein level

Keywords: DN، غالب منفی است; CAK, CDK-activating kinase; CDK, cyclin-dependent kinase; CKI, CDK inhibitor; CHX, cycloheximide; DN, dominant negative; GSK-3β, glycogen synthase kinase 3β; INK4, inhibitors of CDK4; JAKs, Janus kinases; KIP, kinase inhibitor proteins; OSM, oncostatin M;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Isoform-specific contribution of protein kinase C to prion processing

Keywords: DN، غالب منفی است; PKC, protein kinase C; ADAM, A Disintegrin And Metalloprotease; PDBu, Phorbol-12-13-dibutyrate; PAGE, polyacrylamide gel electrophoresis; ECL, enhanced chemiluminescence; HEK, human embryonic kidney; DN, dominant negative; CA, constitutively active; CJD,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Expression Pattern, Regulation, and Functions of Methionine Adenosyltransferase 2β Splicing Variants in Hepatoma Cells

Keywords: DN، غالب منفی است; AP-1, activator protein 1; DN, dominant negative; EGF, epidermal growth factor; ERK, extracellular signal–regulated kinase; IGF, insulin-like growth factor; JNK, c-Jun-N-terminal kinase; MAT, methionine adenosyltransferase; NF-κB, nuclear factor κB; RNAi,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK

Keywords: DN، غالب منفی است; BMP, bone morphogenetic protein; TGFβ, transforming growth factor beta; ERK, extracellular signal-related kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RT-PCR, reverse transcription polymerase chain reaction; DN, dominant negative; JP, juvenile

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Role of PKCδ in IFN-γ-inducible CIITA gene expression

Keywords: DN، غالب منفی است; DC, dendritic cell; IRF-1, interferon regulatory factor-1; PKC, protein kinase C; HAT, histone acetyltransferases; DN, dominant negative; ChIP, chromatin immunoprecipitation; qRT-PCR, quantitative real-time PCR; HPRT, hypoxantine guanine phosphoribosyl tr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Venezuelan equine encephalitis virus infection of mosquito cells requires acidification as well as mosquito homologs of the endocytic proteins Rab5 and Rab7

Keywords: DN، غالب منفی است; VEEV, Venezuelan equine encephalitis virus; SFV, Semliki forest virus; SIN, Sindbis virus; VSV, vesicular stomatitis virus; MLV, murine leukemia virus; WT, wild type; DN, dominant negative; CA, constitutively active; env, envelope proteinAlphavirus; Virus

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-Myc

Keywords: DN، غالب منفی است; β-TrCP, β-transducin repeat-containing protein; DN, dominant negative; HBV, hepatitis B virus; HBx, X protein of HBV; IgH, Immunoglobulin heavy chain; HA, haemagglutinin; HCC, hepatocellular carcinoma; LRR, leucine-rich repeat; SCF, Skp1-Cullin1-F box pro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression

Keywords: DN، غالب منفی است; DN, dominant negative; GFP, green fluorescence protein; NIMA, never in mitosis, gene A; NRK, NIMA-related kinase; siRNA, small interfering RNANIMA; Kinase; Centrosome; Multipolar spindle; Chromosome segregation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Glycogen synthase kinase 3β together with 14-3-3 protein regulates diabetic cardiomyopathy: Effect of losartan and tempol

Keywords: DN، غالب منفی است; ANP, natriuretic peptide; AT1, angiotensin II type 1; BW, body weight; DN, dominant negative; GSK, glycogen synthase kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HW, heart weight; HW/BW, the ratio of HW to BW; JNK, c-Jun NH2 terminal kinase; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Pressure overload induces greater hypertrophy and mortality in female mice with p38α MAPK inhibition

Keywords: DN، غالب منفی است; LV, Left ventricular; H, hypertrophy; DN, dominant negative; TG, dominant negative p38α; WT, wild type; MAPK, mitogen-activated protein kinase; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling; DAPI, 4′,6-diamidine-2′-phenylind

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

NFATc1 regulation of the human β3 integrin promoter in osteoclast differentiation

Keywords: DN، غالب منفی است; BLAST, basic local alignment search tool; mBMM, mouse bone marrow macrophage; bp, base pairs; CTR, calcitonin receptor; cath K, cathepsin K; dn, dominant negative; TBE, Tris Buffered EDTA; EMSAs, electrophoretic mobility shift assays; HA, hemagglutinin; I

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Critical roles of AMP-activated protein kinase in the carcinogenic metal-induced expression of VEGF and HIF-1 proteins in DU145 prostate carcinoma

Keywords: DN، غالب منفی است; ACC, acetyl-CoA carboxylase; AMPK, AMP-activated protein kinase; As, sodium arsenite; Co, cobalt chloride; DN, dominant negative; ELISA, enzyme-linked immunosorbent assay; ERK, extracellular-regulated kinase; GSH, reduced glutathione; HIF-1, hypoxia-induc

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Protein kinase Cα and sphingosine 1-phosphate-dependent signaling in endothelial cell

Keywords: DN، غالب منفی است; AdV, adenovirus; Ca2+, calcium ion; CHO, Chinese hamster ovary; DAG, diacylglycerol; DN, dominant negative; DOG, 1,2-dioctanoyl-sn-glycerol; DTT, dithiothreitol; EDG, endothelial differentiating gene; FBS, fetal bovine serum; GF109203X, bisindolylmaleimid

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

c-Fos Is a Critical Mediator of Inflammatory-Mediated Repression of the Apical Sodium-Dependent Bile Acid Transporter

Keywords: DN، غالب منفی است; AP-1, activator protein 1; ASBT, apical sodium dependent bile acid transporter; bp, base pairs; dAP-1, downstream activator protein 1; dn, dominant negative; hGH, human growth hormone; IL, interleukin; Ost, organic solute transporter; PCR, polymerase chai

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه