دانلود مقالات ISI درباره Dna-Pk + ترجمه فارسی

Regulation and protection of mitochondrial physiology by sirtuins

Keywords: Acetyl-CoA; acetyl-coenzyme A; AceCS2; acetyl-coenzyme A synthethase 2; ACC; Acetyl-CoA carboxylase; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; 5′ adenosine monophosphate-activated protein kinase; ANT; adenine nucleotide transloca

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage

Keywords: Ara-C; cytarabine; ATM; ataxiatelangiectasia-mutated; ATR; ATM- and Rad3-related; CAT; catalase; CHK2; the checkpoint kinase 2; CK1; casein kinase 1; DHE; dihydroethidium; DNA-PK; DNA-dependent serine/threonine protein kinase; Grx; glutaredoxin; HAT; hist

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, DNA-PK inhibition, anti-platelet activity studies of 2-(N-substituted-3-aminopyridine)-substituted-1,3-benzoxazines and DNA-PK and PI3K inhibition, homology modelling studies of 2-morpholino-(7,8-di and 8-substituted)-1,3-benzoxazines

Keywords: Synthesis; 2-Amino-substituted-1,3-benzoxazines; DNA-PK; PI3K inhibition; Homology modelling; Anti-platelet activity;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2012 سفارش ترجمه

DNA-dependent protein kinase (DNA-PK) inhibitors: Structure–activity relationships for O-alkoxyphenylchromen-4-one probes of the ATP-binding domain

Keywords: DNA repair; DNA-PK; Kinase inhibitors; Anticancer drugs; Structure–activity relationship studies

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Impact of PARP-1 and DNA-PK expression on survival in patients with glioblastoma multiforme

Keywords: Glioblastoma multiforme; Postoperative radiotherapy; Survival; PARP-1; DNA-PK;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Dual inhibition of the homologous recombinational repair and the nonhomologous end-joining repair pathways in chronic lymphocytic leukemia therapy

Keywords: Nilotinib; Imatinib; Chronic lymphocytic leukemia; DNA-PK; c-abl; DNA damage and repair mechanisms; Nonhomologous end-joining repair; Homologous recombinational repair;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Emerging roles of DNA-PK besides DNA repair

Keywords: DNA-PK; Cell proliferation; DNA repair; Gene regulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Choosing the right path: Does DNA-PK help make the decision?

Keywords: a-NHEJ; alternative non-homologous end joining; B-NHEJ; backup non-homologous end joining; c-NHEJ; classical non-homologous end joining; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent kinase catalytic subunit; DSB; double strand break; HR;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors

Keywords: DNA repair; DNA-PK; Kinase inhibitors; Chemopotentiation; Radiopotentiation; Anticancer drugs;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

DNA-PK/Ku complex binds to latency-associated nuclear antigen and negatively regulates Kaposi’s sarcoma-associated herpesvirus latent replication

Keywords: LANA; KSHV; DNA-PK; Ku; Latent replication

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin

Keywords: DNA-PK; DNA damage; Camptothecin; Proteasome; Topoisomerase I

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Purification and characterization of exonuclease-free Artemis: Implications for DNA-PK-dependent processing of DNA termini in NHEJ-catalyzed DSB repair

Keywords: Artemis; DNA end processing; NHEJ; DNA-PK

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Suppression of DNA-PKcs enhances FGF-2 dependent human endothelial cell proliferation via negative regulation of Akt

Keywords: DNA-PK; Endothelial cells; Proliferation; Akt; Fibroblast growth factor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Common mechanisms of PIKK regulation

Keywords: ATR; ATM; DNA-PK; mTOR; SMG1; PIKK

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

DNA-dependent protein kinase is a novel interaction partner for Ets-1 isoforms

Keywords: Ets-1; Protein–protein interaction; Streptavidin pull-down; DNA-PK; Phosphorylation; Transcriptional regulation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaks

Keywords: DNA-PK; hnRNP-U; SAF-A; DNA damage; Etoposide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence

Keywords: Ionizing radiation; DNA repair; Non-homologous end joining (NHEJ); Homologous recombination; Double-Strand Breaks; DNA-PK; DNA ligase III; Histone H1; PARP-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Hepatitis C virus-core protein facilitates the degradation of Ku70 and reduces DNA-PK activity in hepatocytes

Keywords: Hepatitis C virus; Core; Ku70; DNA-PK; Hepatocellular carcinoma; WRL68

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Ku, Artemis, and ataxia-telangiectasia-mutated: Signalling networks in DNA damage

Keywords: AT; ataxia-telangiectasia; ATM; ataxia-telangiectasia-mutated; ATR; ataxia-telangiectasia and Rad3-related; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; catalytic subunit of DNA-dependent protein kinase; DSBs; double-strand breaks; ROS; reactive oxygen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

8-Biarylchromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK)

Keywords: DNA-PK; Kinase inhibitor; DNA-repair; Chromenones; Cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Radiosensitization of cervical cancer cells via double-strand DNA break repair inhibition

Keywords: LY294002; PI3K; H2AX; Cervical cancer; DSB; HeLa; DNA-PK

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Activation of protein kinase Cε stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation

Keywords: Radiation; PKCε; P-Tyr; EGFR; DNA-PK; DNA-repair

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo

Keywords: TR; T cell receptor; Ig; immunoglobulin; RSS; recombination signal sequence; SE; signal end; CE; coding end; SJ; signal joint; CJ; coding joint; NHEJ; non-homologous end joining; DSB; double strand break; TdT; terminal nucleotidyl transferase; DNA-PK; DNA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway

Keywords: Cadmium; DSB repair; NHEJ; DNA-PK; MRE11

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks

Keywords: XLF; DNA-PK; Phosphorylation; Nonhomologous end joining

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks

Keywords: Mouse embryonic stem cells; Double-strand break repair; γH2AX; DNA-PK

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Mutations to Ku reveal differences in human somatic cell lines

Keywords: NHEJ; Ku; DNA-PK; Gene targeting; Telomeres; Human somatic cell lines

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase η-deficient human cells treated with cisplatin and oxaliplatin

Keywords: ICL; interstrand crosslink; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR interacting protein; PIKK; PI-3 kinase-related protein kinase; DNA-PK; DNA-dependent protein kinase; Polη; DNA polymerase η; RPA; replication protein A

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Chromium-mediated apoptosis: Involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes

Keywords: p53; p21; PUMA; DNA-PK; ATM; ATR; DNA damage

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2008 سفارش ترجمه

The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation

Keywords: Radiation; EGFR; DNA-PK; P-Tyr; DNA-repair

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

2-Step purification of the Ku DNA repair protein expressed in Escherichia coli

Keywords: Ku; DNA-PK; Non-homologous end-joining; NHEJ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: Involvement of ATM pathway

Keywords: ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related protein; DMSO; dimethyl sulfoxide; DNA-PK; DNA-activated protein kinase; DSB; DNA double-strand break; ERK; extracellular signal-regulated protein kinase; HRP; horseradish peroxidase; MAPK; mitogen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Camptothecin acts synergistically with imatinib and overcomes imatinib resistance through Bcr-Abl independence in human K562 cells

Keywords: Imatinib; Camptothecin; Resistance; DNA-PK; Bcr-Abl; Combination

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK

Keywords: DNA double-strand breaks repair; DNA non-homologous end-joining (NHEJ); DNA ligase IV; Ku heterodimer; BRCA-1 C-terminal (BRCT); DNA-PK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Artemis Phosphorylated by DNA-dependent Protein Kinase Associates Preferentially with Discrete Regions of Chromatin

Keywords: Artemis; DNA damage; DNA-PK; phosphorylation; variable, diversity, joiningV(D)J, variable, diversity, joining; NHEJ, non-homologous DNA end-joining; DNA-PK, DNA-dependent protein kinase; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; CIP, calf

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis

Keywords: Apoptosis; Ku70; Bax; Ubiquitination; Ku80; DNA-PK

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity

Keywords: Radiation; EGFR; DNA-PK; C225; DNA-repair;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Phosphorylation of histone H2AX at M phase in human cells without DNA damage response

Keywords: Phosphorylation; H2AX; M phase; DNA damage; Double-strand break; ATM; DNA-PK; ATR; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Quantum dots-based reverse phase protein microarray

Keywords: Quantum dots; Protein microarray; Bioconjugation; Tyramide signal amplification; Reverse phase protein lysate microarray; DNA-PK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Sirtuins (histone deacetylases III) in the cellular response to DNA damage-Facts and hypotheses

Keywords: CBP; CREB-binding protein; DNA-PK; DNA-dependent protein kinase; DSB; DNA double strand break; FOXO; forkhead box class O; Gadd45; growth arrest and DNA damage response gene; HAT; histone acetyltransferase; HDAC; histone deacetylase; Mn-SOD; manganese sup

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

DNA-PK is responsible for enhanced phosphorylation of histone H2AX under hypertonic conditions

Keywords: γH2AX; ATM; DNA-PK; Double-strand breaks; Comet assay;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Modulation of DNA-dependent protein kinase activity in chlorambucil-treated cells

Keywords: Cbl; chlorambucil (N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid); dsbs; DNA double-strand breaks; NHEJ; nonhomologous end joining; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; ROS; reactive oxygen species; NAC; N-acetyl-L-cysteine; NBT; n

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70

Keywords: DNA damage; Apoptosis; Friend virus; DNA-PK; ATM;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Resistance against Friend leukemia virus-induced leukemogenesis in DNA-dependent protein kinase (DNA-PK)-deficient scid mice associated with defective viral integration at the Spi-1 and Fli-1 site

Keywords: Retrovirus infection; Friend virus; DNA-PK; ATM; Integration;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

The role of SMG-1 in nonsense-mediated mRNA decay

Keywords: NMD; nonsense-mediated mRNA decay; EJC; exon-junction complex; PTC; premature translation termination codon; IC; initial SMG-1-Upf1 complex; PIKK; phosphoinositide 3-kinase related kinase; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3 related;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Sp1: Regulation of gene expression by phosphorylation

Keywords: CCSP; Clara cell secretary protein; CDK; cyclin-dependent kinase; CK-II; casein kinase-II; CRH; corticotropin-releasing hormone; DNA-PK; DNA-dependent protein kinase; EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; FGF-2; fibrobl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Ionizing radiations in Caenorhabditis elegans induce poly(ADP-ribosyl)ation, a conserved DNA-damage response essential for survival

Keywords: 3AB; 3-aminobenzamide; ATM; ataxia telangectasia mutated; DBD; DNA binding domain; DHBB; dihydroxyboronyl Bio-Rex; DHQ; 1,5-dihydroxyisoquinoline; DMSO; dimethyl sulfoxide; DNA-PK; DNA-dependent protein kinase; EDTA; ethylene diamine tetraacetic acid; IPT

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction

Keywords: α-Particles; Boron neutron capture reaction; DNA-PK; Poly(ADP-ribosyl)ation inhibitors; PARP-1;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Ionizing radiation and genetic risks

Keywords: AS; Angelman syndrome; BEIR Committee; Biological Effects of Ionizing Radiation committee of the U.S. National Academy of Sciences; BFB; Breakage fusion bridge cycle; CMT1A; Charcot-Marie-Tooth disease type 1A; DGS/VCFS; Di George/Velocardiofacial syndrom

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2005 سفارش ترجمه