Keywords: 5-hydroxymethylcytosine; Oral squamous cell carcinoma; DNA demethylation; Epigenetics immunohistochemistry;
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A rapid mass spectrometric method for the measurement of catalytic activity of ten-eleven translocation enzymes
Keywords: DNA demethylation; TET enzymes; β-Glucosyltransferase; MALDI mass spectrometry; Michaelis-Menten parameters; TET inhibitors;
Keywords: 5-Hydroxymethylcytosine; Bisulfite sequencing; Oxidation; DNA demethylation; Single base resolution
Keywords: Epigenetics; DNA methylation; DNA demethylation; Histone modification; MicroRNA; Autoimmune disease; Systemic lupus erythematosus;
Keywords: AID/APOBEC; activation-induced cytidine deaminase/apolipoprotein B mRNA-editing enzyme complex; BDNF; brain-derived neurotrophic factor; 5caC; 5-carboxylcytosine; CBP; CREB binding protein; CREB; cAMP response binding protein; DNMT; DNA methyltransferases
Keywords: 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AS3MT; arsenite methyltransferase; DNMT; DNA methyltransferase; SAM; S-adenosylmethionine; TET; tetmethylcytosinedioxygenase; Arsenic; DNA methylation; DNA demethylation; 5-Hydroxymethylcytosine; 5-Met
Keywords: cDNA; complementary DNA; DAPI; 4',6'-Diamino-2-Phenylindole; DNMT; DNA methyltransferase; DMEM; Dulbecco's minimal essential medium; FCS; fetal calf serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GS; glutamine synthetase; MeCP2; methyl-CpG-
Keywords: Electrochemical DNA sensor; DNA demethylation; DNA demethylase; Endonuclease; Redox label
DNA methylation dynamics in aging: how far are we from understanding the mechanisms?
Keywords: DNA methylation; DNA demethylation; Aging; Chromatin; Histones;
Silencing of metallothionein 1A gene in melanoma
Keywords: DNA methylation; DNA demethylation; MT1A; Melanoma; Trace element;
DNA demethylation mediated by down-regulated TETs in the testes of rare minnow Gobiocypris rarus under bisphenol A exposure
Keywords: Bisphenol A; DNA demethylation; Ten-eleven translocation proteins; Mechanism; Gobiocypris rarus;
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
Keywords: 5-hydroxymethylcytosine; 5-methylcytosine; 5-formylcytosine; 5-carboxycytosine; DNA demethylation; Epigenetics;
Hypomethylation of BORIS is a promising prognostic biomarker in hepatocellular carcinoma
Keywords: HCC; hepatocellular carcinoma; BORIS; the brother of the regulator of the imprinted site; CTCF; CCCTC-binding factor; ZF; zinc finger; MSP; methylation-specific PCR; ICR; imprinting control regions; PVTT; portal vein tumor thrombus; TNM; tumor node metast
DNA demethylation pattern of in-vitro fertilized and cloned porcine pronuclear stage embryos
Keywords: DNA demethylation; 5-Hydroxymethylcytosine; Pronuclear stage; In-vitro fertilized porcine embryos; Cloned porcine embryo;
Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1
Keywords: DNA methylation; DNA demethylation; MAGEB2; Neurofibromatosis type 1; Malignant peripheral nerve sheath tumor
Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation
Keywords: Epigenetics; Structure-based screening; Ligand-based screening; DNA demethylation; Compound NSC232003; QM-dockingQWGHGQJMUGAQJR-UHFFFAOYSA-N; YNYDWEIQSDFDLK-UHFFFAOYSA-N; IXSSYZRLNVZFMP-ARJAWSKDSA-N
AP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations in CpGs during base excision repair
Keywords: DNA demethylation; Base excision repair; DNA damage; DNA polymerase β; AP endonuclease 1; CpG islands
Defective DNA methylation in salivary gland epithelial acini from patients with Sjögren's syndrome is associated with SSB gene expression, anti-SSB/LA detection, and lymphocyte infiltration
Keywords: Sjögren's syndrome; DNA demethylation; Anti-SSB antibodies; Lymphocytes;
OGG1 is essential in oxidative stress induced DNA demethylation
Keywords: OGG1; 8-Oxoguanine DNA glycosylase-1; 8-oxoG; 8-Oxoguanine; ROS; reactive oxygen species; α-KG; α-Ketoglutarate; MeDIP; methylated DNA immunoprecipitations; 5mC; 5-Methyl cytosine; 5hmC; 5-Hydroxymethyl cytosine; 5fC; 5-Formylcytosine; 5caC; 5-Carboxylc
Stimulation of ribosomal RNA gene promoter by transcription factor Sp1 involves active DNA demethylation by Gadd45-NER pathway
Keywords: ChIP; chromatin immunoprecipitation; NER; nucleotide excision repair; NoRC; nucleolar remodeling complex; PBS; phosphate-buffered saline; Pol I; RNA polymerase I; qRT-PCR; quantitative real time-polymerase chain reaction; rDNA; ribosomal DNA; Sp1; Specifi
Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword
Keywords: DNA methylation; DNA demethylation; Deamination; TET proteins; TDG; Base excision repair; Mismatch repair
GADD45a physically and functionally interacts with TET1
Keywords: Gadd45; TET; DNA demethylation; LC-MS/MS; hmC;
Role of the mevalonate pathway in specific CpG site demethylation on AGEs-induced MMP9 expression and activation in keratinocytes
Keywords: Diabetic dermopathy; Mevalonate pathway; MMP9; DNA demethylation; cis-Promoter;
From development to diseases: The role of 5hmC in brain
Keywords: 5-hydroxymethylcytosine; DNA demethylation; Brain; Development; Neurological disorders
Enzyme-based electrochemical biosensor for sensitive detection of DNA demethylation and the activity of DNA demethylase
Keywords: DNA demethylation; DNA demethylase activity; Electrochemical biosensor; Alkaline phosphatase;
Inhibition of maintenance DNA methylation by Stella
Keywords: Stella; Np95; Dnmt1; DNA demethylation
SUMO-modification and elimination of the active DNA demethylation enzyme TDG in cultured human cells
Keywords: Small ubiquitin-related modifier (SUMO); Thymine DNA glycosylase (TDG); Ring finger protein 4 (RNF4); SUMO-targeted ubiquitin ligase (STUbL); Cell cycle; DNA demethylation;
The red sport of 'Zaosu' pear and its red-striped pigmentation pattern are associated with demethylation of the PyMYB10 promoter
Keywords: Pear; Pyrus hybrid; Rosaceae; Anthocyanin; DNA demethylation; Red skin mutation; Striped pattern;
Connections between TET proteins and aberrant DNA modification in cancer
Keywords: TET; 5-hydroxymethylcytosine; 5mC; 5hmC; DNA methylation; DNA demethylation; cancer; IDH; OGT
DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients
Keywords: Brain derived neurotrophic factor (BDNF); DNA demethylation; DNA methyltransferase (DNMT); Epigenetic; Glucocorticoid receptor (GCortR); Ten-eleven-translocation hydroxylase (TET);
Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats
Keywords: Cystathionine-β-synthetase; DNA demethylation; Dorsal root ganglia; Epigenetics; Inflammatory pain; Voltage-gated sodium channels;
Genome-wide distribution of DNA methylation and DNA demethylation and related chromatin regulators in cancer
Keywords: DNA methylation; DNA demethylation; 5mC; 5hmC; DNMT; TET
IL-2 and GM-CSF are regulated by DNA demethylation during activation of T cells, B cells and macrophages
Keywords: MeDIP; immunoprecipitation of methylated DNA; DNMT; DNA methyltransferase; AID; activation-induced deaminase; APOBEC; apolipoprotein B-editing catalytic; Gadd45; growth arrest and DNA-damage-inducible 45; Tet; ten-eleven-translocation proteins; DNA demeth
Promoter demethylation of Keap1 gene in human diabetic cataractous lenses
Keywords: ARCs; age-related cataracts; ARE; antioxidant response element; 5-Aza; 5-aza-2â² deoxycytidine; BGS; bisulfite genomic DNA sequencing; EthD; ethidium homodimer-III; ER; endoplasmic reticulum; FCS; fetal calf serum; HLECs; human lens epithelial cells; Kea
CpG site-specific alteration of hydroxymethylcytosine to methylcytosine beyond DNA replication
Keywords: hmC; hydroxymethylcytosine; mC; methylcytosine; mCpG; methylcytosine in CpG dinucleotides; DNMTs; DNA methyltransferases; ESCs; embryonic stem cells; T4-BGT; T4 β-glucosyltransferase; GFP; green fluorescent protein; MoCEV; modified cytosine in episomal v
5-Aza-2′-deoxycytidine treatment induces skeletal myogenic differentiation of mouse dental pulp stem cells
Keywords: 5-Aza, 5-Aza-2′-deoxycytidine; DPSC, dental pulp stem cell; MSC, mesenchymal stem cell; BM, bone marrowDental pulp; Mesenchymal stem cell; DNA demethylation; Myogenic differentiation
DNA methylation and demethylation probed by small molecules
Keywords: DNA methylation; Small molecules; 5-azaC; Epigenetics; Anticancer drug; DNA demethylation; SAM; MBD2
Active DNA demethylation and DNA repair
Keywords: DNA demethylation; DNA repair; Excision repair
On the mechanism of demethylation of 5-methylcytosine in DNA
Keywords: Gas chromatography–mass spectrometry; DNA; Methylcytosine; Demethylation; DNA demethylation
Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells
Keywords: Arsenite; Epigenetics; DNA demethylation; Hepatoma; Gene reactivation
Preventing transcriptional gene silencing by active DNA demethylation
Keywords: Arabidopsis; DNA methylation; DNA demethylation; ROS1; DNA glycosylase; Transcriptional gene silencing