دانلود مقالات ISI درباره Dnmt1 + ترجمه فارسی

Subcellular distribution of cyclin-dependent kinase-like 5 (CDKL5) is regulated through phosphorylation by dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)

Keywords: CDKL5; DYRK1A; Protein phosphorylation; Rett syndrome; Down syndrome; Amph1; amphiphysin 1; CDKL5; cyclin-dependent kinase-like 5; Dnmt1; DNA methyltransferase 1; DYRK1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A; GST; glutathione S-tr

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Alteration of methylation status in the ATXN3 gene promoter region is linked to the SCA3/MJD

Keywords: SCA3/MJD; ATXN3 promoter; Dynamic mutation; Anticipation; DNA methylation; DNMT1;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects

Keywords: 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; ACTB; b-actin; ASD; autism spectrum disorder; BA; Brodmann area; BDNF; brain derived neurotrophic factor; BDNF-IV; BDNF-promoter 4; BDNF-IX; BDNF-promote

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

The RNAs of RNA-directed DNA methylation

Keywords: AGO1; ARGONAUTE 1; AGO2; ARGONAUTE 2; AGO4; ARGONAUTE 4; AGO6; ARGONAUTE 6; CLSY1; CLASSY 1; CMT2; CHROMOMETHYLASE 2; CMT3; CHROMOMETHYLASE 3; CTD; carboxy-terminal domain; DCL1; DICER-LIKE 1; DCL2; DICER-LIKE 2; DCL3; DICER-LIKE 3; DCL4; DICER-LIKE 4; DD

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis

Keywords: α-SMA; α-smooth muscle actin; ApoER2; apolipoprotein E receptor 2; CASK; calcium/calmodulin-dependent serine protein kinase; Dab1; Disabled-1; DSS; dextran sulphate sodium; DNMT1; (DNA (Cytosine-5-)-Methyltransferase 1); IL-1β; interleukin-1β; PDGF-BB

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver

Keywords: Hotair; LncRNA HOX transcript antisense RNA; HSCs; hepatic stellate cells; PRC2; polycomb repressive complex 2; H3K27me3; histone H3-lysine27; DNMT1; DNA methyltransferase 1; α-SMA; alpha smooth muscle actin; Col1a1; alpha1(1) collagen; NcRNA; non-coding

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

DNA methyltransferase 1 rs16999593 genetic polymorphism decreases risk in patients with transposition of great arteries

Keywords: TGA; Transposition of the great arteries; SNPs; single nucleotide polymorphisms; dTGA; Dextro-transposition of the great arteries; DNMT1; DNA methyctransferase 1; ASD; atrial septal defect; VSD; ventricular septal defect; PDA; patent ductus arteriosus; HW

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina

Keywords: Dnmt1; Dnmt3a; Dnmt3b; Epigenetics; Retina; OPL; DNA methylation; 5mC; 5hmC;

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of Klotho on fibrosis and cancer: A renal focus on mechanisms and therapeutic strategies

Keywords: ACE; angiotensin converting enzyme; ADAM; a disintegrin and metalloproteinase; AKI; acute kidney injury; ANGII; angiotensin II; AT1; angiotensin II receptor type 1; AMPKα; AMP-activated protein kinase α; α-SMA; α-smooth muscle actin; CKD; chronic kidn

دانلود رایگان متن کامل مقاله ISI 82 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluating long-term cellular effects of the arsenic species thio-DMAV: qPCR-based gene expression as screening tool

Keywords: Thio-dimethylarsinic acid; Long-term cellular toxicity; qPCR-based gene expression screening; GADD45A and GADD45G; DNMT1; Cellular damage response;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Loss of maintenance DNA methylation results in abnormal DNA origin firing during DNA replication

Keywords: DNA replication; DNA methylation; DNMT1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Neonatal hyperoxia induces alterations in neurotrophin gene expression

Keywords: BDNF; GDNF; DNA methylation; Hyperoxia; DNMT1; DNMT3a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Physcion 8-O-β-glucopyranoside induces apoptosis, suppresses invasion and inhibits epithelial to mesenchymal transition of hepatocellular carcinoma HepG2 cells

Keywords: Physcion 8-O-β-glucopyranoside; DNMT1; Sp1; ROS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Interplay between menin and Dnmt1 reversibly regulates pancreatic cancer cell growth downstream of the Hedgehog signaling pathway

Keywords: Menin; Dnmt1; Pancreatic cancer cell growth; p18; p27; Methylation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Expression of DNA methyltransferases 1 and 3B correlates with EZH2 and this 3-marker epigenetic signature predicts outcome in glioblastomas

Keywords: DNMT1; DNMT3A; DNMT3B; EZH2; GBM; Survival;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Chinese herbal medicine Xiaoji decoction inhibited growth of lung cancer cells through AMPKα-mediated inhibition of Sp1 and DNA methyltransferase 1

Keywords: NSCLC; Xiaoji decoction; AMPKα; Sp1; DNMT1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

An integrated genomic analysis of Tudor domain-containing proteins identifies PHD finger protein 20-like 1 (PHF20L1) as a candidate oncogene in breast cancer

Keywords: Breast cancer; Copy number alteration; Tudor domain; Methylation; PHF20L1; TDRD; Tudor domain-containing protein; PHD; plant homeodomain; PHF20L1; PHD finger protein 20-like 1; DNMT1; DNA (cytosine-5-)-methyltransferase 1; TCGA; The Cancer Genome Atlas;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Distinct and overlapping DNMT1 interactions with multiple transcription factors in erythroid cells: Evidence for co-repressor functions

Keywords: DNMT1; Transcription factors; Erythropoiesis; Epigenetics;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop

Keywords: Breast cancer; MiR-152; DNMT1; CpG-island, H3K4me3; CDH1 gene

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells

Keywords: Preeclampsia; miR-148a/152; DNMT1; FABP4; DNA methylation;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

MiR-211 is epigenetically regulated by DNMT1 mediated methylation and inhibits EMT of melanoma cells by targeting RAB22A

Keywords: MiR-211; DNMT1; Methylation; RAB22A; Melanoma; EMT;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

The replication foci targeting sequence (RFTS) of DNMT1 functions as a potent histone H3 binding domain regulated by autoinhibition

Keywords: DNA methylation; DNMT1; UHRF1; Ubiquitin; Histone H3; RFTS;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions

Keywords: ACAT1; acetoacetyl-CoA thiolase; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleoside; AMPK; AMP-activated protein kinase; ATAC; Ada-two-A-containing; BET; bromodomains and extra-terminal motif; BMAL1; PAS domain-containing pr

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Long noncoding RNAs: Lessons from genomic imprinting

Keywords: lncRNA; long noncoding RNA; DMR; Differentially methylated region; ICR; Imprinting control region; PWS; Prader-Willi syndrome; AS; Angelmann syndrome; MEGs; Maternally expressed genes; TTS; Triplex target sites; TFO; Triplex forming oligo; IG-DMR; Inter

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development

Keywords: Epigenetics; Uhrf1; Dnmt1; DNA methylation; Zebrafish development; Epiboly;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Piwil1 causes epigenetic alteration of PTEN gene via upregulation of DNA methyltransferase in type I endometrial cancer

Keywords: Piwil1; PTEN; DNMT1; Endometrial cancer; DNA methylation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Research reportAcute stress affects the global DNA methylation profile in rat brain: Modulation by physical exercise

Keywords: Acute stress; Epigenetics; DNA methylation; Physical exercise; Dnmt1; Bdnf;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Research paperPromoter hypermethylation of let-7a-3 is relevant to its down-expression in diabetic nephropathy by targeting UHRF1

Keywords: DM; diabetes mellitus; DN; diabetic nephropathy; miRNAs; microRNAs; UTR; untranslated regions; qMSP; quantitative methylation-specific PCR; UHRF1; ubiquitin-like, containing PHD and RING finger domains; DNMT1; DNA (cytosine-5)-methyltransferase 1; UAER; u

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

Keywords: Epigenetics; Methylation; Schizophrenia; Bipolar disorder; Glutamate decarboxylase; DNMT1; TET1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1

Keywords: Dnmt, DNA methyltransferase; ES cells, embryonic stem cells; 5hmC, hydroxymethylcytosine; 5mC, methylcytosine; SAM, S-adenosyl-l-methionine; Tet, ten eleven translocation; 2i, two kinase inhibitorsHydroxymethylcytosine; Bisulfite sequencing; DNMT1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis

Keywords: Burkitt lymphoma; DNMT1; DNMT3A; DNMT3B; miR-29 family; Decitabine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Quercetin protects mouse liver against nickel-induced DNA methylation and inflammation associated with the Nrf2/HO-1 and p38/STAT1/NF-κB pathway

Keywords: Quercetin; Nickel; Inflammation; Nrf2; STAT1; Liver; ALT; alanine aminotransferase; AST; aspartate aminotransferase; DNMT1; DNA methyltransferase 1; HO-1; heme oxygenase-1; IL-1β; interleukin-1 beta; iNOS; inducible nitric oxide synthase; NF-κB; nuclear

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Perinatal nicotine exposure suppresses PPARγ epigenetically in lung alveolar interstitial fibroblasts

Keywords: α-SMA; Alpha smooth muscle actin; ATII; Alveolar epithelial type II; Aza-CdR; 5-Aza-2′-deoxycytidine; ChIP; Chromatin immunoprecipitation; DMSO; Dimethyl sulfoxide; DNMT1; DNA methyltransferase 1; LIFs; Lipofibroblasts; MSP; Methylation-specific-PCR; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Lipoprotein lipase deficiency leads to α-synuclein aggregation and ubiquitin C-terminal hydrolase L1 reduction

Keywords: AD; Alzheimer's disease; DMEM; Dulbecco's modified Eagle medium; DNMT1; DNA cytosine-5-methyltransferase 1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; LPL; Lipoprotein lipase; PBS; phosphate-buffered saline; PC; Phosphatidylcholine; PCR; polymer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis, chemical characterization, computational studies and biological activity of new DNA methyltransferases (DNMTs) specific inhibitor. Epigenetic regulation as a new and potential approach to cancer therapy

Keywords: Organotin(IV); Caffeic acid; DNMT1; DNA methylation; Cancer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Non-coding RNA repertoires in malignant pleural mesothelioma

Keywords: AD; adenocarcinoma; ADARB2; RNA-specific adenosine deaminase, B2; aCGH; array comparative genomic hybridization; BAPE; benign asbestos-related pleural effusion; CCND1; cyclin D1; ceRNA; competing endogenous RNA; CREB; cAMP response element binding protein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats

Keywords: ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; BPA; bisphenol A; CpG; cytosine phosphate guanine; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA me

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

High-methionine diets accelerate atherosclerosis by HHcy-mediated FABP4 gene demethylation pathway via DNMT1 in ApoE−/− mice

Keywords: AS; atherosclerosis; Hcy; homocysteine; HHcy; Hyperhomocysteinemia; ApoE−/−; apolipoprotein E knockout; FABP4; fatty acid-binding protein 4; DNMT1; DNA methyltransferases 1; SAH; S-adenosylhomocysteine; SAM; S-adenosylmethionine; TC; total Cholesterol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Original ArticlePolysomnographic and neurometabolic features may mark preclinical autosomal dominant cerebellar ataxia, deafness, and narcolepsy due to a mutation in the DNA (cytosine-5-)-methyltransferase gene, DNMT1

Keywords: ADCA-DN; DNMT1; Narcolepsy; MSLT; MR spectroscopy; Genetic; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

RANKL expression in myeloma cells is regulated by a network involving RANKL promoter methylation, DNMT1, microRNA and TNFα in the microenvironment

Keywords: MM; Multiple myeloma; RANKL; receptor for activation of the nuclear factor-κB ligand; BM; bone marrow; BMSCs; bone marrow mesenchymal stromal cells; RANKL; Myeloma microenvironment; DNA methylation; DNMT1; MicroRNA; TNFα;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of maintenance DNA methylation by Stella

Keywords: Stella; Np95; Dnmt1; DNA demethylation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Polymorphism in DNMT1 may modify the susceptibility to oligospermia

Keywords: DNMT1; male infertility; oligospermia; polymorphism; SNP; spermatogenesis impairment;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Mallory-Denk Body (MDB) formation modulates ufmylation expression epigenetically in alcoholic hepatitis (AH) and non-alcoholic steatohepatitis (NASH)

Keywords: AH; alcoholic hepatitis; CGI; CpG island; DDC; diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridine-dicarboxylate; DNMT1; DNA (cytosine-5-)-methyltransferase 1; ER; endoplasmic reticulum; HCC; hepatocellular carcinoma; MDB; Mallory-Denk Body; NASH; non-alco

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages

Keywords: RAW264.7 mouse macrophage cell line; Suppressors of cytokine signaling1 (SOCS1); Hypermethylation; DNA methyltransferase1 (DNMT1); Pro-inflammatory cytokines; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IL-6; interleukin 6; SOCS; suppressor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats

Keywords: Liver fibrosis; Hepatic stellate cell (HSC); DNA methylation; DNA methyltransferase 1 (DNMT1); Smad7; α-SMA; alpha-smooth muscle actin; Col1a1; alpha1(1) collagen; ECM; extracellular matrix; TGF-β1; transforming growth factor-β1; DNMT1; DNA methyltrans

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Gallic acid protects against endothelial injury by restoring the depletion of DNA methyltransferase 1 and inhibiting proteasome activities

Keywords: Gallic acid; Endothelial injury; DNMT1; Proteasome;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts

Keywords: H2-DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; 5-Aza; 5-aza-2′-deoxycytidine; 5-mC; 5-methylcytosine; ATF; activating transcription factor; AID; activation-induced deaminase; AGE; advanced glycation end-product; ARC; age-related cataract; A

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

DNA methylation: New therapeutic implications for hepatic fibrosis

Keywords: HSCs; hepatic stellate cells; ECMs; extracellular matrices; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; DNMTs; DNA methyltransferases; DNMT1; DNA methyltransferase 1; 5-Aza-dC; 5-Aza-2′-de

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1

Keywords: DNMT1; DNA methyltransferase1; EGCG; epigallocatechin-3-gallate; ROS; reactive oxygen species; UHRF1; Ubiquitin-like PHD, Ring finger 1; DNA methyltransferase 1; Epigallocatechin-3-gallate; P16INK4A; Tumor suppressor gene; Ubiquitin-like containing PHD an

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The H19 induction triggers trophoblast lineage commitment in mouse ES cells

Keywords: ESCs; embryonic stem cells; ICM; inner cell mass; PE; primitive ectoderm; TE; trophectoderm; Parp-1; poly(ADP-ribose) polymerase 1; Plf1; proliferin 1; Dnmt1; DNA methyltransferase 1; Gapdh; glyceraldehyde 3-phosphate dehydrogenase; Tc; tetracycline; Zeo;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه