Keywords: گیرنده دوپامین D3; Dopamine supersensitivity; Dopamine D2 receptor; Dopamine D3 receptor; Locomotor activity; Haloperidol; Blonanserin;
مقالات ISI گیرنده دوپامین D3 (ترجمه نشده)
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Keywords: گیرنده دوپامین D3; Cariprazine; Dopamine D3 receptor; Schizophrenia; Phencyclidine (PCP); Cognition; Negative symptoms;
Dopamine D3 receptor blockade rescues hyper-dopamine activity-induced deficit in novel object recognition memory
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Dopamine transporter; Novel object recognition;
Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia
Keywords: گیرنده دوپامین D3; Parkinson's disease; L-DOPA-Induced dyskinesia; Abnormal involuntary movements; D1R-D3R interactions; DA; Dopamine; DOPAC; Dihydroxyphenylacetic acid; PD; Parkinson's disease; LID; L-DOPA-Induced Dyskinesia; D1R; Dopamine D1 Receptor; D2R; Dopamine D2 Rec
Molecular mechanisms involved in epidermal growth factor receptor-mediated inhibition of dopamine D3 receptor signaling
Keywords: گیرنده دوپامین D3; EGFR; epidermal growth factor receptor; D3R; dopamine D3 receptor; GFP; green fluorescent protein; Veh; vehicle; CRE-luci; cAMP response element-luciferase; GRK2; G protein-coupled receptor kinase 2; KD; knockdown; Forsk; forskolin; Co-IP; co-immunoprecip
Dopamine D3 receptor status modulates sexual dimorphism in voluntary wheel running behavior in mice
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Knockout model; Physical activity; Wheel running; Sexual dimorphism;
The EGF receptor inhibits the signaling of dopamine D3 receptor through the phosphorylation of GRK2 on tyrosine residues
Keywords: گیرنده دوپامین D3; EGFR; Dopamine D3 receptor; Protein kinase C; GRK2; β-Arrestin;
Development of molecular tools based on the dopamine D3 receptor ligand FAUC 329 showing inhibiting effects on drug and food maintained behavior
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Selective D3 antagonist; Subtype selectivity; Positron emission tomography (PET); Fluorine-18; Autoradiography; Self-administration; Drug maintained behavior; Food maintained behavior;
The antipsychotic-like effects in rodents of YQA31 involve dopamine D3 and 5-HT1A receptor
Keywords: گیرنده دوپامین D3; Schizophrenia; Dopamine D3 receptor; 5-HT1A receptor; Novel object recognition; Hyperactivity;
The adrenergic α2 antagonist atipamezole alters the behavioural effects of pramipexole and increases pramipexole concentration in blood plasma
Keywords: گیرنده دوپامین D3; Pramipexole; Dopamine D3 receptor; Dopamine D2 receptor; Atipamezole; α2 adrenergic receptor; Locomotion; Operant responding;
The atypical antipsychotic blonanserin reverses (+)-PD-128907- and ketamine-induced deficit in executive function in common marmosets
Keywords: گیرنده دوپامین D3; Common marmoset; Schizophrenia; Object retrieval with detour (ORD) task; Blonanserin; Dopamine D3 receptor; Ketamine
Effect of a D3 receptor antagonist on context-induced reinstatement of nicotine seeking
Keywords: گیرنده دوپامین D3; DRD3; Dopamine D3 receptor; DRD2; Dopamine D2 receptor; CSs; conditioned stimuli; CSÂ +; excitatory conditioned stimulus; FR; fixed ratio; ANOVA; Analysis of Variance; SEM; Standard Error of the Mean; Context-induced reinstatement; D3; Dopamine; Rat; SB-2
Clathrin-mediated endocytosis is responsible for the lysosomal degradation of dopamine D3 receptor
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Protein kinase C; Desensitization; Internalization; Degradation;
In vivo characterization of a novel dopamine D3 receptor agonist to treat motor symptoms of Parkinson's disease
Keywords: گیرنده دوپامین D3; Agonist; Abnormal involuntary movements; Adjuvant therapy; Dopamine D3 receptor; l-dopa induced dyskinesia; Optimal therapy; Parkinson's disease; Pharmacokinetics; Stepping test;
Design, synthesis and evaluation of bitopic arylpiperazinephenyl-1,2,4-oxadiazoles as preferential dopamine D3 receptor ligands
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Phenyl-1,2,4-oxadiazoles; Structure–activity relationship; Molecular modeling
RalA employs GRK2 and β-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor
Keywords: گیرنده دوپامین D3; Dopamine D2 receptor; Dopamine D3 receptor; Filamin A; RalA; GRK2; β-arrestin;
Multiple actions of a D3 dopamine receptor agonist, PD128907, on GABAergic inhibitory transmission between medium spiny neurons in mouse nucleus accumbens shell
Keywords: گیرنده دوپامین D3; NAc, nucleus accumbens; MSN, medium spiny neuron; FSI, fast-spiking interneuron; sIPSC, spontaneous inhibitory postsynaptic currentDopamine; Dopamine D3 receptor; GABAergic transmission; Lateral inhibition; Medium spiny neurons; Nucleus accumbens
Low dose pramipexole causes D3 receptor-independent reduction of locomotion and responding for a conditioned reinforcer
Keywords: گیرنده دوپامین D3; Pramipexole; Dopamine D3 receptor; Dopamine D2 receptor; [3H]-(+)-PHNO; Locomotion; Operant responding;
Synthesis and evaluation of arylpiperazine-reverse amides as biased dopamine D3 receptor ligands
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Reverse amide; Selectivity; Structure-activity relationships; Molecular modeling;
Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam
Keywords: گیرنده دوپامین D3; Anxiety; Dopamine D3 receptor; GABAA; Alpha6 subunit; Diazepam; BDNF
Dopamine D3 receptor agonists as pharmacological tools
Keywords: گیرنده دوپامین D3; Affinity; Dopamine D3 receptor; Efficacy; GPCR; Pharmacophore; Selectivity
Molecular characterization and differential expression of multiple goose dopamine D2 receptors
Keywords: گیرنده دوپامین D3; DRD2; Dopamine D2 receptor; cDNA; complementary to RNA; bp; base pair(s); RT-PCR; reverse transcription polymerase chain reaction; SNPs; single nucleotide polymorphisms; indel; insert-deletion; DRD1; Dopamine D1 receptor; DRD3; Dopamine D3 receptor; DRD4;
A novel dopamine D3 receptor antagonist YQA14 inhibits methamphetamine self-administration and relapse to drug-seeking behaviour in rats
Keywords: گیرنده دوپامین D3; Methamphetamine (METH); YQA14; Dopamine D3 receptor; Self-administration; Drug reward; Relapse;
Virtual fragment screening on GPCRs: A case study on dopamine D3 and histamine H4 receptors
Keywords: گیرنده دوپامین D3; Fragment screening; Fragment docking; Virtual screening; Ensemble docking; G protein-coupled receptors; Dopamine D3 receptor; Histamine H4 receptorGPCR, G protein-coupled receptor; FBLD, fragment-based lead discovery; LE, ligand efficiency; LELP, ligand-e
Selective Overexpression of Dopamine D3 Receptors in the Striatum Disrupts Motivation but not Cognition
Keywords: گیرنده دوپامین D3; Cognition; dopamine D3 receptor; motivation; schizophrenia; striatum; transgenic model
ReviewDopamine D3 receptor as a new pharmacological target for the treatment of depression
Keywords: گیرنده دوپامین D3; Depression; Dopamine D3 receptor; Brain-derived neurotrophic factor; Partial agonist; Treatment-resistant depression; Aripiprazole;
Acutely administered antipsychotic drugs are highly selective for dopamine D2 over D3 receptors
Keywords: گیرنده دوپامین D3; Antipsychotic drugs; Dopamine D2 receptor; Dopamine D3 receptor; Selectivity; [3H]-(+)-PHNO; Rat
Ovariectomy-mediated impairment of spatial working memory, but not reference memory, is attenuated by the knockout of the dopamine D3 receptor in female mice
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Ovariectomy; Spatial memory; Morris water maze
The potential role of dopamine D3 receptor neurotransmission in cognition
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Cognition; Dopamine D3 receptor antagonist
The dopamine D1 but not D3 receptor plays a fundamental role in spatial working memory and BDNF expression in prefrontal cortex of mice
Keywords: گیرنده دوپامین D3; Dopamine D1 receptors; Dopamine D3 receptor; Spatial working memory; Morris water maze; BDNF
Dopamine D3 receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats
Keywords: گیرنده دوپامین D3; Methamphetamine; Dopamine D3 receptor; SB-277011A; Self-administration; Reward; Reinstatement
Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Parkinson's disease; Hybrid dopamine agonists; 7-OH-DPAT; 5-OH-DPAT; Homology modeling
Roles of BDNF, dopamine D3 receptors, and their interactions in the expression of morphine-induced context-specific locomotor sensitization
Keywords: گیرنده دوپامین D3; BDNF; Dopamine D3 receptor; Morphine; Nucleus accumbens; Sensitization
Functional potencies of dopamine agonists and antagonists at human dopamine D2 and D3 receptors
Keywords: گیرنده دوپامین D3; Antiparkinson; Antipsychotic; Dopamine D2 receptor; Dopamine D3 receptor; Functional potency; cAMP
In vitro pharmacology of aripiprazole, its metabolite and experimental dopamine partial agonists at human dopamine D2 and D3 receptors
Keywords: گیرنده دوپامین D3; Aripiprazole; Psychosis; Antipsychotic; Dopamine D2 receptor; Dopamine D3 receptor; Partial agonist
Dopamine D3 receptor regulates basal but not amphetamine-induced changes in pain sensitivity in mice
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Pain sensitivity; Amphetamine; Mice
The possible involvement of dopamine D3 receptors in the regulation of gastric emptying in rats
Keywords: گیرنده دوپامین D3; S(+)-PD 128,907; (+)-S 14297; Gastric emptying; Dopamine D3 receptor; Rats
Genetic polymorphisms in the dopamine-2 receptor (DRD2), dopamine-3 receptor (DRD3), and dopamine transporter (SLC6A3) genes in schizophrenia: Data from an association study
Keywords: گیرنده دوپامین D3; Dopamine D2 receptor; Dopamine D3 receptor; Dopamine transporter; Genetic association; Schizophreniabp, base pair; CI, confidence interval; df, degrees of freedom; COMT, catechol-O-methyl transferase; DAT, dopamine transporter; DAT1, dopamine transporter
Association of brain-derived neurotrophic factor (Val66Met) genetic polymorphism with methamphetamine dependence in a Malaysian population
Keywords: گیرنده دوپامین D3; BDNF; brain-derived neurotrophic factor; DRD3; dopamine D3 receptor; Val; valine; Met; methionine; OR; odds ratio; CI; confidence interval; SD; standard deviation; N and n; number; Brain-derived neurotrophic factor; Methamphetamine dependence; Psychosis;
(+)-UH 232, a partial agonist of the D3 dopamine receptors, attenuates cognitive effects of angiotensin IV and des-Phe6-angiotensin IV in rats
Keywords: گیرنده دوپامین D3; Angiotensin IV; Des-Phe6-angiotensin IV; (+)-UH 232; Dopamine D3 receptor; Stereotype behaviour; Memory; Rat
Baseline plasma epinephrine levels predict Wisconsin Card Sorting Test scores in healthy volunteers
Keywords: گیرنده دوپامین D3; Plasma; Epinephrine; Norepinephrine; Lymphocytes; Dopamine D3 receptor; Wisconsin Card Sorting Test; Healthy humans
Effects of the DRD3 Ser9Gly polymorphism on aripiprazole efficacy in schizophrenic patients as modified by clinical factors
Keywords: گیرنده دوپامین D3; DRD2, dopamine D2 receptors; DRD3, dopamine D3 receptors; PANSS, positive and negative syndrome scale; RFLP, restriction fragment length polymorphismAripiprazole; Dopamine D3 receptor; DRD3 Ser9Gly polymorphism
Characterization of aripiprazole partial agonist activity at human dopamine D3 receptors
Keywords: گیرنده دوپامین D3; Aripiprazole; Antipsychotic; Dopamine D3 receptor; Ser9Gly polymorphism; Schizophrenia; Partial agonist
Synthesis of new carbon-11-labeled carboxamide derivatives as potential PET dopamine D3 receptor radioligands
Keywords: گیرنده دوپامین D3; Carboxamides; Carbon-11; Positron emission tomography (PET); Imaging; Dopamine D3 receptor
Further SAR study on 11-O-substituted aporphine analogues: Identification of highly potent dopamine D3 receptor ligands
Keywords: گیرنده دوپامین D3; Aporphine analogues; Dopamine D3 receptor; 5-HT1A receptor; Arylpiperazine; Click reaction;
Effects of the selective dopamine D3 receptor antagonist SB-277011A on the reinforcing effects of nicotine as measured by a progressive-ratio schedule in rats
Keywords: گیرنده دوپامین D3; Nicotine; Self-administration; Dopamine D3 receptor; Antagonist; SB-277011A
The dopamine D3 receptor antagonist NGB 2904 increases spontaneous and amphetamine-stimulated locomotion
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Knockout mice; Amphetamine; NGB 2904; Locomotor activity
Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activation
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Antipsychotics; Schizophrenia; ERK 1/2; G proteins
Dopamine D3 receptor ligands—Recent advances in the control of subtype selectivity and intrinsic activity
Keywords: گیرنده دوپامین D3; Dopamine D3 receptor; Agonist; Antagonist; Structure activity relationship; Rational drug discovery; G protein-coupled receptor
Design of novel hexahydropyrazinoquinolines as potent and selective dopamine D3 receptor ligands with improved solubility
Keywords: گیرنده دوپامین D3; Hexahydropyrazinoquinolines; Dopamine D3 receptor; Ligands