دانلود مقالات ISI درباره دوز محدودیت سمیت + ترجمه فارسی

سیکلوفسفامید، آلووسییدیب (فلاووپیریدول) و ریتوکسیماب، یک رژیم جدید شیمی امینو تراپی امکان پذیر برای بیماران مبتلا به لوسمی لنفوسیتی مزمن

Cyclophosphamide, alvocidib (flavopiridol), and rituximab, a novel feasible chemoimmunotherapy regimen for patients with high-risk chronic lymphocytic leukemia

Keywords: دوز محدودیت سمیت; B2M; beta 2 microglobulin; CAR; cyclophophamide, alvocidib, rituximab; CDK; cyclin-dependent kinase; CLL; chronic lymphocytic leukemia; CR; complete response; CRS; cytokine release syndrome; DLT; dose limiting toxicity; ECOG; Eastern Cooperative Oncology

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Bispecific antibodies for cancer therapy: A review

Keywords: دوز محدودیت سمیت; ADCC; antibody-dependent cell-mediated cytotoxicity; AE; adverse events; ALL; acute lymphoblastic leukemia; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; B-ALL; B-cell acute lymphoblastic leukemia; BiTES; Bi-sp

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Systematic comparison of the statistical operating characteristics of various Phase I oncology designs

Keywords: دوز محدودیت سمیت; Phase 1 designs; Oncology; Dose finding; Rule-based designs; Model-based designs; Accuracy of MTD selection; DLT; dose limiting toxicity; MTD; maximum tolerated dose; mTPI design; modified toxicity probability interval design; TEQR design; toxicity equiva

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Maximising the potential of AKT inhibitors as anti-cancer treatments

Keywords: دوز محدودیت سمیت; AE; adverse event; CRPC; castrate resistant prostate cancer; DLT; dose limiting toxicity; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; GSK3β; glycogen synthase kinase beta; INPP4B; polyphosphate 4-phosphatase type II; MTD; maximum tole

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Safety and efficacy of valproic acid treatment in SCA3/MJD patients

Keywords: دوز محدودیت سمیت; Efficacy; PolyQ disease; Spinocerebellar ataxia type 3/Machado-Joseph disease; Tolerability; Valproic acid; DLT; dose limiting toxicity; MTD; maximum tolerated dose;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

An FDA oncology analysis of immune activating products and first-in-human dose selection

Keywords: دوز محدودیت سمیت; MABEL; Immune oncology; First-in-human dose; ADCC; antibody-dependent cellular cytotoxicity; CRA; cytokine release assay; CRS; cytokine release syndrome; DLT; dose limiting toxicity; EMA; European Medicines Agency; FIH; first-in-human; HHD; highest human

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Is sunitinib a Narrow Therapeutic Index Drug? - A systematic review and in vitro toxicology-analysis of Sunitinib vs. Imatinib in cells from different tissues

Keywords: دوز محدودیت سمیت; Apoptosis; Drug safety; Imatinib; Narrow Therapeutic Index Drug (NTID); Receptor tyrosine kinase (RTK); Sunitinib; Toxicity; Tyrosine kinase inhibitor (TKI); Cell viability; ALL; acute lymphoblastic leukemia; AUC; area under the curve; b.i.d.; twice daily

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents – Dose-Limiting Toxicity and Toxicity Assessment Recommendation Group for Early Trials of T

Keywords: دوز محدودیت سمیت; Phase 1; Targeted agents; Dose limiting toxicity; Maximum tolerated dose; Recommended phase 2 dose; Toxicities; Trial design

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Phase I/II Multicenter Study of Transarterial Chemoembolization with a Cisplatin Fine Powder and Porous Gelatin Particles for Unresectable Hepatocellular Carcinoma: Japan Interventional Radiology in Oncology Study Group Study 0401

Keywords: دوز محدودیت سمیت; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CR; complete response; DEB; drug-eluting bead; DLT; dose limiting toxicity; EASL; European Association for the Study of the Liver; GP; gelatin particle; HAIC; hepatic arterial infusion chemot

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

CommentaryClinical perspectives for irreversible tyrosine kinase inhibitors in cancer

Keywords: دوز محدودیت سمیت; AE; adverse event; BTK; Bruton's tyrosine kinase; CI; confidence interval; CLL; chronic lymphocytic leukemia; CR; complete response; DTL; dose limiting toxicity; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor receptor; HR; hazard r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

MS-275, a potent orally available inhibitor of histone deacetylases-The development of an anticancer agent

Keywords: دوز محدودیت سمیت; AML; acute myeloid leukemia; CLL; chronic lymphocytic leukemia; CPA; cyproterone acetate; CRA; cis-retinoic acid; CTCL; cutaneous T-cell lymphoma; DLT; dose limiting toxicity; EGFR; epithelial cell growth factor receptor; FDA; Food and Drug Administration

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia

Keywords: دوز محدودیت سمیت; AML; acute myeloid leukemia; ALL; acute lymphoblastic leukemia; CR; complete response; PR; partial response; ara-C; cytarabine; MDR1; multidrug resistance; Pgp; P-glycoprotein; SWOG; southwest oncology group; DLT; dose limiting toxicity; MTD; maximum tole

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

A Bayesian evaluation of enrolling additional patients at the maximum tolerated dose in Phase I trials

Keywords: دوز محدودیت سمیت; Dose escalation; Dose limiting toxicity; Posterior density;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه