Keywords: شکست دو رشته; RIBE; radiation-induced bystander effect; TIBE; tumour-induced bystander effect; SCE; sister chromatid exchange; ROS; reactive oxygen species; NO; nitric oxide; NF-kappaB; nuclear factor-kappa B; COX-2; cyclooxygenase-2; FA; Fanconi anaemia; ATM; ataxia-t
مقالات ISI شکست دو رشته (ترجمه نشده)
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Keywords: شکست دو رشته; %TL; percentage of tail length; ANOVA; analysis of variance; CAs; chromosome aberrations; CBMN; cytokinesis-block micronuclei; CTAs; chromatid type aberrations; DNA; deoxyribonucleic acid; DSB; double strand break; EDTA; ethylene diamine tetra acetic acid
Keywords: شکست دو رشته; CRISPR-Cas9; Kluyveromyces lactis; Kluyveromyces marxianus; Scheffersomyces stipitis; Yarrowia lipolytica; Hansenula polymorpha; Pichia pastoris; HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; double strand break; CRISPR; Clustered re
Keywords: شکست دو رشته; REM; RNA-guided endonuclease mediated; EEM; Engineered endonuclease mediated; CRISPR/Cas; Clustered regularly interspersed short palindromic repeats/ CRISPR associated sequence; TALE; Transcription Activator-like Effectors; TALEN; Transcription Activator-
Keywords: شکست دو رشته; ABC; ATP binding cassette; ADCC; antibody-dependent cell-mediated cytotoxicity; ALDH; aldehyde dehydrogenase; CBP; cAMP response element binding protein (CREB)-binding protein; CSC; cancer stem cell; CTC; circulating tumour cell; DAPT; N-[N-(3,5-difluorop
Keywords: شکست دو رشته; CI; confidence interval; CV; coefficient of variation; DSB; double strand break; DSBR; double strand break repair; HR; homologous recombination; NHEJ; non-homologous end-joining; OR; odds ratio; PBL; peripheral blood lymphocytes; PCR-RFLP; polymerase chai
Keywords: شکست دو رشته; MMR; DNA mismatch repair; HR; homologous recombination; DSB; double strand break; ssDNA; single strand DNA; dsDNA; double strand DNA; SDSA; synthesis dependent strand annealing; DSBR; double strand break repair; CO; cross over; NCO; non cross over; SSA; s
Keywords: شکست دو رشته; ARS; autonomously replicating sequence; CEN; centromere; CRISPR; Clustered, Regularly Interspaced, Short Palindromic Repeats; DSB; double strand break; GFP; green fluorescent protein; GRAS; Generally Regarded As Safe; gRNA; guide RNA (for CRISPR); HR; hom
Keywords: شکست دو رشته; 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia
Keywords: شکست دو رشته; NGF; nerve growth factor; DSB; double strand break; SSB; single strand break; ATR; ataxia telangiectasia and Rad3 related protein; ATM; ataxia telangiectasia mutated protein; Shh; sonic hedgehog; DPP; decapentaplegic; NPC; neuronal progenitor cell; PSM; p
Keywords: شکست دو رشته; Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex
Application and development of genome editing technologies to the Solanaceae plants
Keywords: شکست دو رشته; Genome editing; Nuclease; Targeted mutagenesis; AGL; agamous-like; AID; activation-induced cytidine deaminase; ALOG; Arabidopsis LSH1 and Oryza G1; ANT; anthocyanin mutant; ARF; auxin-response factor; Aux; auxin-induced; BAK; brassinosteroid kinase; BOP;
Possible use of Punica granatum (Pomegranate) in cancer therapy
Keywords: شکست دو رشته; 27HC; 27-hydroxycholesterol; 8-OHdG; 8-hydroxy-2â² -deoxyguanosine; 8-oxodG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; APC; adenomatous polyposis coli; AR; androgen receptors; AOM; azoxymethane; ATP; adenosine triphosphate; B(a)P; benzo(a)pyrene; Bad; Bcl-2
Efficient transgene insertion in a pseudorabies virus vector by CRISPR/Cas9 and marker rescue-enforced recombination
Keywords: شکست دو رشته; ASFV; African swine fever virus; BAC; bacterial artificial chromosome; Cas9; CRISPR associated protein 9; CRISPR; clustered regularly interspaced short palindromic repeats; DSB; double strand break; EGFP; enhanced green fluorescent protein; FBS; fetal bov
MiR-192 and miR-662 enhance chemoresistance and invasiveness of squamous cell lung carcinoma
Keywords: شکست دو رشته; AC; adenocarcinoma; CDH; cadherin; CTA(s); cancer/testis antigen(s); DSB; double strand break; EMT; epithelial-mesenchymal transition; LCC; large cell carcinoma; lncRNA(s); long non-coding RNA(s); miRNA(s); microRNA(s); NSCLC; non-small cell lung cancer;
Unusual interaction of human apurinic/apyrimidinic endonuclease 1 (APE1) with abasic sites via the Schiff-base-dependent mechanism
Keywords: شکست دو رشته; APE1; DNA repair; AP sites; Clustered DNA damage; Schiff base; MALDI-TOF mass spectrometry; AP site; apurinic/apyrimidinic site; DSB; double strand break; BER; base excision repair; BHT; borohydride trapping; BS-AP DNA; DNA containing AP sites in both str
The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential
Keywords: شکست دو رشته; APC/C; anaphase-promoting complex/cyclosome; ASF1; antisilencing function 1; BRAF35; BRCA2-associated factor 35; BRCA2; breast cancer 2 protein; CAF-1; chromatin assembly factor 1; CR; cysteine rich; DCIS; ductal carcinoma in situ; DNMT3B; DNA methyltrans
Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: A brief overview
Keywords: شکست دو رشته; HEase; homing endonuclease; ZFN; zinc finger nuclease; TALEN; TAL-effector nuclease; DSB; double strand break; dCas9; catalytically inactive (dead) Cas9; RNP; ribonucleoprotein; Genome editing; CRISPR; Cas9; High-throughput methods; PAM library;
Cell cycle arrest mediated by Cd-induced DNA damage in Arabidopsis root tips
Keywords: شکست دو رشته; CDKs; Cyclin-dependent kinases; CYCB1;1; Cyclin B1;1; qRT-PCR; Real time quantitative reverse transcription-polymerase chain reaction; BRCA1; Breast cancer susceptibility1; PCNA; Proliferation cell nuclear antigen; DSB; Double strand break; GR1; Gamma res
Radiothérapie et biomarqueurs de la réparation de l'ADN
Keywords: شکست دو رشته; Biomarqueur; ADN; Réparation de l'ADN; Cassure double brin; Radiothérapie; DNA; DNA repair; Biomarker; Double strand break; Radiotherapy;
Poetry in motion: Increased chromosomal mobility after DNA damage
Keywords: شکست دو رشته; HR; homologous recombination; DSB; double strand break; HS; homology search; MMS; methylmethane sulfonate; NHEJ; non-homologous end joining; SCE; sister chromatid exchange; PCNA; proliferating cell nuclear antigen; SDSA; synthesis dependent strand anneali
Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine
Keywords: شکست دو رشته; ACN; acetonitrile; BER; base excision repair; C.V.; coefficient of variation; DMSO; dimethylsulfoxide; DSB; double strand break; EMA; European Medicine Agency; FDA; Food and Drug Administration; GLP; Good Laboratory Practice; HRR; homologous recombination
Nanoparticle-mediated knockdown of DNA repair sensitizes cells to radiotherapy and extends survival in a genetic mouse model of glioblastoma
Keywords: شکست دو رشته; GBM; glioblastoma; Ape1; apurinic endonuclease 1; DSB; double strand break; BER; base excision repair; siGFP; siRNA against green fluorescent protein; siApe1; siRNA against Ape1; PEI; polyethyleneimine; CTX; chlorotoxin; CP; chitosan-grafted PEG; NP; nano
Structural and functional relationships of FAN1
Keywords: شکست دو رشته; FA, FANC; Fanconi anemia; ICL; interstrand cross-link; DSB; double strand break; TLS; translesion synthesis; HR; homologous recombination; ID2; FANCD2/FANCI; AP; apurinic/apyrimidinic; UBZ; ubiquitin-binding zinc finger; Ub; ubiquitin or ubiquitinated; SA
Radiation-induced clustered DNA lesions: Repair and mutagenesis
Keywords: شکست دو رشته; LET; linear energy transfer; MDS; multiply damaged site; SSB; single strand break; DSB; double strand break; AP sites; abasic sites; 8-oxoG; 8-oxo-7,8-dihydroguanine; 5-ohU; 5-hydroxyuracil; Tg; 5,6-dihydroxy-5,6-dihydrothymine; U; uracil; BER; base excis
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)
Keywords: شکست دو رشته; 9-1-1 complex; complex of Rad9 Rad1 and Hus1 proteins; A2E; N-retinylidene-N-retinylethanol-amine; AtRal; all-trans retinal; AMD; age-related macular degeneration; AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATM; ataxia-telangiectasia
Maximising the potential of AKT inhibitors as anti-cancer treatments
Keywords: شکست دو رشته; AE; adverse event; CRPC; castrate resistant prostate cancer; DLT; dose limiting toxicity; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; GSK3β; glycogen synthase kinase beta; INPP4B; polyphosphate 4-phosphatase type II; MTD; maximum tole
ReviewTargeting telomerase and telomeres to enhance ionizing radiation effects in in vitro and in vivo cancer models
Keywords: شکست دو رشته; TMM; telomere maintenance mechanism; T/TTC; telomere/telomerase targeting compound; G4; G-quadruplex; DSB; double strand break; ALT; alternative lengthening of telomeres; GBM; glioblastoma multiforme; AS-ODN; antisense oligonucleotide; TIF; telomere-induc
Role for RIF1-interacting partner DDX1 in BLM recruitment to DNA double-strand breaks
Keywords: شکست دو رشته; BLM; Bloom syndrome helicase; DDX1; DEAD Box 1; DSB; double strand break; Gy; gray; HR; homologous recombination; IR; ionizing radiation; NHEJ; non-homologous end joining; RIF1; Rap1-interacting factor 1; RNase; ribonuclease; DNA double strand break repai
MLN4924 suppresses the BRCA1 complex and synergizes with PARP inhibition in NSCLC cells
Keywords: شکست دو رشته; Neddylation; BRCA1; PARP1; NSCLC; Double strand break;
Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer's disease
Keywords: شکست دو رشته; Aβ; amyloid β; AD; Alzheimer's disease; AFT complexes; APP/AICD-FE65-TIP60 complexes; AICD; APP intracellular domain; APLP1,2; amyloid precursor like protein 1,2; APP; amyloid precursor protein; ChIP; chromatin immuneprecipitation; CTF; C-terminal fra
CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B
Keywords: شکست دو رشته; CRIPSR/Cas9; Pladienolide B; Spliceosome; Pre-mRNA splicing; Drug target validation; Drug discovery; SSNs; Site Specific Nucleases; ZFN; Zing Finger Nucleases; TALENs; Transcription Like Effector Nucleases; CRISPR; Clustered Regulatory Interspaced Short P
Regulation of DNA repair by non-coding miRNAs
Keywords: شکست دو رشته; miRNAs; DNA damage; DNA repair; Genomic instability; DSB repair; NER; DSB; double strand break; HR; homologous recombination; NHEJ; non-homologous end joining; NER; nucleotide excision repair; BER; base excision repair; TLS; translesion synthesis; FA; Fan
Modulation of ionizing radiation-induced effects by NU7441, KU55933 and VE821 in peripheral blood lymphocytes
Keywords: شکست دو رشته; Ionizing radiation; Lymphocytes; KU55933; NU7441; VE821; ATM; ataxia-telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related protein kinase; DMSO; dimethyl sulfoxide; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; Gy; g
Getting it done at the ends: Pif1 family DNA helicases and telomeres
Keywords: شکست دو رشته; DSB; double strand break; G4; G-quadruplex; TERRA; (telomere repeat containing RNA); ALT; alternative lengthening of telomeres; BIR; break induced replication; Sc; Saccharomyces cerevisiae; TA; telomere addition; CST; Cdc13-Stn1-Ten1; ChIP; chromatin immu
A new light on the meiotic DSB catalytic complex
Keywords: شکست دو رشته; Topoisomerase; Meiosis; Recombination; Double strand break; SPO11;
I-SceI enzyme mediated integration (SEMI) for fast and efficient gene targeting in Trichoderma reesei
Keywords: شکست دو رشته; Hypocrea jecorina; Non-homologous-end-joining; Double strand break; Homologous integration; Ade1;
Cells redox environment modulates BRCA1 expression and DNA homologous recombination repair
Keywords: شکست دو رشته; bp; base pairs; BRCA1; breast cancer type 1 susceptibility protein; CO3â¢â; carbonate; DETA; DETA NONOate; DSB; double strand break; EtBr; ethidium bromide; ETC; electron transport chain; FAD; flavin adenine dinucleotide; FADH; reduced flavin adenine d
High-resolution genomic assays provide insight into the division of labor between TLS and HDR in mammalian replication of damaged DNA
Keywords: شکست دو رشته; BER; base excision repair; BP-G; benzo[a]pyrene-guanine adduct; CPD; cyclobutane pyrimidine dimer; CRISPR; clustered regularly-interspaced short palindromic repeats; CSTR; complementary strand transfer repair; DDT; DNA damage tolerance; DSB; double strand
Advancements in zebrafish applications for 21st century toxicology
Keywords: شکست دو رشته; CRISPR; Clustered, regularly interspaced, short palindromic repeats; Dpf; Days post fertilization; DSB; Double strand break; Hpf; Hours post fertilization; HSC; Hematopoietic stem cell; HTS; High-throughput screen; KO; Knockout; MO; Morpholino oligonucleo
Suppression of OsKu80 results in defects in developmental growth and increased telomere length in rice (Oryza sativa L.)
Keywords: شکست دو رشته; Rice (Oryza sativa L.); Ku80; Ku70/Ku80 heterodimer; Developmental growth; Telomere; Genome stability; BiFC; bimolecular fluorescence complementation; ChIP; chromatin immuno-precipitation; DSB; double strand break; HR; homologous recombination; NHEJ; non-
Nrf2 promotes survival following exposure to ionizing radiation
Keywords: شکست دو رشته; ARE; antioxidant response element; ARS; acute radiation syndrome; ATM; ataxia telangiectasia mutated; BRCA1; breast cancer type 1 susceptibility protein; ChIP; chromatin immunoprecipitation; CnC; cap 'n׳ collar family of basic leucine zipper transcript
DisA and c-di-AMP act at the intersection between DNA-damage response and stress homeostasis in exponentially growing Bacillus subtilis cells
Keywords: شکست دو رشته; DNA damage response; Single-strand gap; Double strand break; RadA; Sms
The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells
Keywords: شکست دو رشته; G4; G quadruplex; TIF; telomere induced dysfunctional foci; GBM; glioblastoma multiforme; ALT; alternative lengthening of telomeres; hTERT; human telomerase catalytic subunit; PCC; premature chromosome condensation; cPDL; cumulative population doubling le
The Nuclear Factor κB pathway: A link to the immune system in the radiation response
Keywords: شکست دو رشته; Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP
Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase
Keywords: شکست دو رشته; RNR; ribonucleotide reductase; GO; Gene Ontology; DDR; DNA damage response; DSB; double strand break; IP; immunoprecipitation; IR; ionizing radiation; MMS; methyl methanesulphonate; ROS; reactive oxygen species; dNTP; deoxyribonucleotide; STRING; Search T
Selenite activates the ATM kinase-dependent DNA repair pathway in human osteosarcoma cells with mitochondrial dysfunction
Keywords: شکست دو رشته; Mitochondrial dysfunction; Selenite; DNA repair; ATM kinase; Oxidative damage; ATM; ataxia teleangiectasia mutated kinase; BRCA1; breast cancer 1; DAF-FM; 4-Amino-5-methylamino-2â²,7â²-difluorofluorescein; DAPI; 4â²,6-diamidino-2-phenylindole; DBS; dou
Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing
Keywords: شکست دو رشته; CRISPR; clustered regularly interspaced short palindromic repeat; PAM; protospacer adjacent motif; gRNA; guide RNA; DSB; double strand break; ORF; open reading frame; MMR; mismatch repair; MEP; methylerythritol-phosphate; ssDNA; single-strand DNA; dsDNA;
Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae
Keywords: شکست دو رشته; CRISPR; clustered regularly interspaced short palindromic repeat; PAM; protospacer adjacent motif; BTS1; Geranylgeranyl pyrophosphate synthase; ROX1; Heme-dependent repressor of hypoxic genes; TALEN; transcription activator-like effector nuclease; gRNA; g
Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks
Keywords: شکست دو رشته; BRCA2; RAD51; Replication fork stalling; Double strand break; Chromosomal instability