دانلود مقالات ISI درباره شکست دو رشته + ترجمه فارسی

A Tissue Graft Model of DNA Damage Response in the Normal and Malignant Human Prostate

Keywords: شکست دو رشته; prostate; prostatic neoplasms; DNA damage; H2AFX protein; human; transplants; α-SMA; α-smooth muscle actin; AMACR; α-methylacyl-coenzyme A-racemase; ATM; ataxia telangiectasia mutated; CK; cytokeratin; DDR; DNA damage response; DSB; double strand break

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Safety evaluation of nonthermal atmospheric pressure plasma liquid treatment: Single DNA molecule-based method

Keywords: شکست دو رشته; Nonthermal plasma; Plasma jet; λDNA Escherichia coli; Double strand break; Safety evaluation; Plasma medicine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer

Keywords: شکست دو رشته; ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights

Keywords: شکست دو رشته; HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2014 سفارش ترجمه

Human Rad51 promotes mitochondrial DNA synthesis under conditions of increased replication stress

Keywords: شکست دو رشته; BrdU; 5-bromo-2′-deoxyuridine; ddC; 2′-3′-dideoxycytidine; DSB; double strand break; EtBr; ethidium bromide; GO; glucose oxidase; HR; homologous recombination; mtDNA; mitochondrial DNA; Rad51; mtDNA replication; mtDNA copy number; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Smad7 foci are present in micronuclei induced by heavy particle radiation

Keywords: شکست دو رشته; ROS; reactive oxygen species; IR; ionizing radiation; DSB; double strand break; TGFβ; transforming growth factor beta; IRIF; IR-induced foci; MN; micronuclei; pSmad2; phospho-Smad2; LET; linear energy transfer; DDR; DNA damage response; HZE; high charge

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Genotoxic potentials and related mechanisms of bisphenol A and other bisphenol compounds: A comparison study employing chicken DT40 cells

Keywords: شکست دو رشته; Polycarbonate; DT40 cell; Homologous recombination; Double strand break; RAD54;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

XRCC1 deficiency increased the DNA damage induced by γ-ray in HepG2 cell: Involvement of DSB repair and cell cycle arrest

Keywords: شکست دو رشته; XRCC1 gene; Hepatocellular carcinoma cells; γ-ray irradiation; DNA damage; DNA repair; BER; base excision repair; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; double strand break; DSBR; double strand break repair; gadd153; growth arrest

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication

Keywords: شکست دو رشته; NO; nitric oxide; OH; hydroxyl radical; dA; 2′-deoxyadenosine; 8oxoA; 8-oxoadenine; FaPyA; 4,6-diamino-5-formamidopyrimidine; HX; hypoxanthine; 8azaA; 8-azaadenine; dGMP; 2′-deoxyguanosine monophosphate; 8azaG; 8-azaguanine; SSB; single strand break;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Studying the cerebellar DNA damage response in the tissue culture dish

Keywords: شکست دو رشته; 53BP1; p53 binding protein 1; AOA1/2; ataxia with oculomotor apraxia type 1; A-T; ataxia-telangiectasia; A-TLD; ataxia-telangiectasia-like disorder/disease; ATM; ataxia-telangiectasia, mutated; ATR; ATM- and Rad3-related protein kinase; CaBP; calbindin pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

Keywords: شکست دو رشته; MDA; malondialdehyde; 4-HNE; 4-hydroxynonenal; EAE; experimental allergic encephalomyelitis; MS; mutiple sclerosis; SSB; single strand break; DSB; double strand break; 8-OxoG; 8-hydroxyguanosine; 8-NO(2)-G; 8-nitroguanine; AP; apurinic/apyrmidinic; OGG1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress

Keywords: شکست دو رشته; 5-FU; 5-fluorouracil; FdUMP; 5-fluoro-2′-deoxyuridylate; FdUrd; 5-fluoro-2′-deoxyuridine; RTX; raltitrexed; TS; thymidylate synthase; TMP; thymidylate; Dump; deoxyuridylate; SSB; single strand break; DSB; double strand break; UDG; uracil DNA glycosyla

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Transcriptomic analysis provides insights on hexavalent chromium induced DNA double strand breaks and their possible repair in midgut cells of Drosophila melanogaster larvae

Keywords: شکست دو رشته; Hexavalent chromium; Double strand break; Drosophila; Non-homologous end joining; In vivo DNA damage;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic polymorphisms in the DNA repair gene XRCC1 and susceptibility to glioma in a Han population in northeastern China: A case-control study

Keywords: شکست دو رشته; CNS; central nervous system; SNPs; single nucleotide polymorphisms; BER; base excision repair; SSBs; single strand breaks; DSB; double strand break; PCR-RFLP; polymerase chain reaction-restriction fragment length polymorphism; HWE; Hardy-Weinberg equi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The PWAPA cassette: Intimate association of a PHD-like finger and a winged-helix domain in proteins included in histone-modifying complexes

Keywords: شکست دو رشته; Sequence analysis; Protein domain; Histone post-translational modifications; PcG; TrxG; ATAC; ASH2; Absent, small or homeotic discs-like 2; ATAC2; ADA2-containing complex; DSB; double strand break; EH; Extended Homology; HAT; histone acetyltransferase; HC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

TAp63γ enhances nucleotide excision repair through transcriptional regulation of DNA repair genes

Keywords: شکست دو رشته; TA; transactivation; NER; nucleotide excision repair; UV; ultraviolet; CPD; cyclobutane pyrimidine dimer; PR; prolin-rich; DBD; DNA binding domain; OD; oligomerization domain; ΔN; amino-terminal truncated; DBS; double strand break; 6-4 PP; 6-4 photop

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells

Keywords: شکست دو رشته; Interstrand crosslink; Double strand break; Homologous recombination; Intact mammalian cells;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Methyl methanesulfonate induces apoptosis in p53-deficient H1299 and Hep3B cells through a caspase 2- and mitochondria-associated pathway

Keywords: شکست دو رشته; MMS; methyl methanesulfonate; DSB; double strand break; MMP; mitochondrial membrane potential; TAp73; transactivation competent p73; DNp73; dominant negative p73; Methyl methanesulfonate; p53; Caspase 2; gammaH2AX; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Global chromatin fibre compaction in response to DNA damage

Keywords: شکست دو رشته; NCS; neocarzinostatin; DSB; double strand break; MNase; micrococcal nuclease; DNA double strand breaks; Chromatin; Histones;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Destroying the ring: Freeing DNA from Ku with ubiquitin

Keywords: شکست دو رشته; Ku70; Ku80; Non-homologous end joining; Double strand break; VCP; Proteasome;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Histone deacetylase inhibitor sodium butyrate enhances cellular radiosensitivity by inhibiting both DNA nonhomologous end joining and homologous recombination

Keywords: شکست دو رشته; DSB; double strand break; FACS; fluorescence activated cell sorting; HAT; histone acetyltransferase; HDAC; histone deacetylase; HR; homologous recombination; NHEJ; nonhomologous end joining; Sodium butyrate; γ-Irradiation; Histone acetylation; DNA nonhom

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival

Keywords: شکست دو رشته; DSB; double strand break; MDS; multiply damaged sites; SSB; single strand break; LET; linear energy transfer; BER; base excision repair; NER; nucleotide excision repair; HR; homologous recombination; NHEJ; non-homologous end-joining; PRR; post-replication

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

Keywords: شکست دو رشته; hEXO1; PCNA; Replication foci; Double strand break; DNA mismatch repair

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Recombination-dependent concatemeric viral DNA replication

Keywords: شکست دو رشته; DA; DNA arrested; DSB; Double Strand Break; dsDNA; double-stranded DNA; HJ; Holliday junction; HSV-1; Herpes-simplex virus type 1; MRN; Mre11-Rad50-Nbs1 complex; ori; origin of replication; OB-fold; oligosaccharide/oligonucleotide binding fold; pac; p

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Choosing the right path: Does DNA-PK help make the decision?

Keywords: شکست دو رشته; a-NHEJ; alternative non-homologous end joining; B-NHEJ; backup non-homologous end joining; c-NHEJ; classical non-homologous end joining; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent kinase catalytic subunit; DSB; double strand break; HR;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Fission yeast telomeres forecast the end of the crisis

Keywords: شکست دو رشته; ATM; ataxia telangiectasia mutated (Tel1 in budding yeast); ATR; ATM and Rad3 Related; ChIP; chromatin immuno-precipitation; DDR; DNA damage response; DSB; double strand break; dsDNA; double stranded DNA; HR; homologous recombination; NHEJ; non-homologous

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Roles of Werner syndrome protein in protection of genome integrity

Keywords: شکست دو رشته; γ-H2AX; phosphorylated histone H2AX; 4-NQO; 4-nitroquinoline 1-oxide; 5-OHdC; 5-hydroxycytidine; 5-OHU; 5-hydroxyuracil; 8-oxodA; 8-oxoadenine; 8-oxodG; 8-oxoguanine; ALT; alternative lengthening of telomeres; APE1; apurinic/apyrimidinic endonuclease 1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Characterisation of a new reporter system allowing high throughput in planta screening for recombination events before and after controlled DNA double strand break induction

Keywords: شکست دو رشته; Double strand break; I-SceI; Glucocorticoid receptor; Homologous recombination; Arabidopsis thalianaCaMV, cauliflower mosaic virus; DSB, double strand break; DSBR, double strand break repair; GR, glucocorticoid receptor; GUS, β-glucuronidase; HR, homologo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta

Keywords: شکست دو رشته; IR; ionizing radiation; DSB; double strand break; SSB; single strand break; BER; base excision repair; SSBR; single strand break repair; polβDN; dominant negative DNA polymerase β; AP; apurinic/apyrimidinic; polβ; DNA polymerase beta; dRP; deoxyribose

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Apex1 can cleave complex clustered DNA lesions in cells

Keywords: شکست دو رشته; furan; tetrahydrofuran; oligonucleotide; oligodeoxyribonucleotide; bps; base pairs; AP; abasic; SSB; single strand break; DSB; double strand break; BER; base excision repair; Fpg; formamidopyrimidine DNA glycosylase; 8oxoG; 8-oxo-7,8-dihydroguanine; Apex1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Therapeutic options for triple-negative breast cancers with defective homologous recombination

Keywords: شکست دو رشته; ABC; ATP-binding cassette; APC; Adenomatous, polyposis coli; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3-related; BER; base-excision repair; BRCA1; Breast cancer susceptibility gene 1; BRCA2; Breast cancer susceptibility gene 2; CGH; Comparative

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

ERCC1 is required for FANCD2 focus formation

Keywords: شکست دو رشته; Fanconi anemia; Interstrand crosslink; ERCC1; Double strand break

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks

Keywords: شکست دو رشته; BER; base excision repair; PARP-1; poly(ADP-ribose) polymerase-1; SSB; single strand break; DSB; double strand break; Pol β; DNA polymerase β; XRCC1; X-ray cross-complementing protein-1; SiRNA; small interfering RNA; PARP-1; DNA repair; Base excision re

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo

Keywords: شکست دو رشته; TR; T cell receptor; Ig; immunoglobulin; RSS; recombination signal sequence; SE; signal end; CE; coding end; SJ; signal joint; CJ; coding joint; NHEJ; non-homologous end joining; DSB; double strand break; TdT; terminal nucleotidyl transferase; DNA-PK; DNA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Double strand break formation as a response to X-ray and targeted proton-irradiation

Keywords: شکست دو رشته; 87.50.Gi; 87.50.−a; 87.58.SpIon microprobe; X-ray; Targeted irradiation; Double strand break

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

RAD51 homologous recombination repair gene haplotypes and risk of acute myeloid leukaemia

Keywords: شکست دو رشته; AML, acute myeloid leukaemia; DSB, double strand break; HR, homologous recombination; NHEJ, non-homologous end joining; FA, Fanconi's anemia; OR, odds ratio; CI, confidence intervalAcute myeloid leukaemia; DNA repair; Double strand break; Homologous recom

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

A subgroup of spinocerebellar ataxias defective in DNA damage responses

Keywords: شکست دو رشته; spinocerebellar ataxia; DNA repair; aprataxin; AOA; AOA1; ataxia oculomotor apraxia type 1; AOA2; ataxia oculomotor apraxia 2; A-T; ataxia-telangiectasia; ATLD; ataxia-telangiectasia-like disorder; dsb; double strand break; EDTA; ethylenediaminetetraaceti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Low-energy electron interactions with liquid water and energy depositions in nanometric volumes

Keywords: شکست دو رشته; 78.90.+t; 87.10.+eElectron interaction; Dielectric function; Liquid water; DNA; Single strand break; Double strand break

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Responding to DNA double strand breaks in the nervous system

Keywords: شکست دو رشته; DNA DSB; ATM; MRN; NHEJ; neurodegeneration; brain tumors; ATLD; ataxia telangiectasia-like disorder; DSB; double strand break; HR; homologous recombination; Lig4; DNA ligase-IV; NBS; Nijmegen breakage syndrome; NHEJ; non-homologous end joining; WRN; Werne

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Pol32 is required for Polζ-dependent translesion synthesis and prevents double-strand breaks at the replication fork

Keywords: شکست دو رشته; Replication; Translesion synthesis; Double strand break; Checkpoint; Recombination repair

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Links between DNA double strand break repair and breast cancer: Accumulating evidence from both familial and nonfamilial cases

Keywords: شکست دو رشته; Breast Cancer; Recombination; Double strand break; Repair; Brca

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Intron exclusion and the mystery of intron loss

Keywords: شکست دو رشته; ADH, Alcohol dehydrogenase; cDMHR, cDNA-mediated homologous recombination; DSB, Double strand break; DSBR, DSB repair; HR, Homologous recombinationIntron loss; Intron exclusion; Double strand break; Homologous recombination; Alcohol dehydrogenase; Genome

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Heterogeneity in premature senescence by oxidative stress correlates with differential DNA damage during the cell cycle

Keywords: شکست دو رشته; ROS; Reactive oxygen species; DSB; Double strand break; BrdU; 5-bromo-2′-deoxyuridine; SA-β-gal; Senescence-associated β-galactosidase; PBS; Phosphate-buffered saline; Oxidative stress; DNA damage; DNA repair; S-phase; Senescence; Ageing;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Does γH2AX foci formation depend on the presence of DNA double strand breaks?

Keywords: شکست دو رشته; γH2AX; Double strand break; Replication arrest; Environmental factors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability

Keywords: شکست دو رشته; XRCC1; X-ray repair cross-complementing gene 1; Pol-β; DNA polymerase-β; PARP-1; poly(ADP-ribose) polymerase 1; Lig III α; DNA ligase III α; APE1; apurinic/apyrimidinic endonuclease 1; CHO; Chinese hamster ovary; BER; base excision repair; SSBR; singl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه