دانلود مقالات ISI درباره تعامل دارو و دارو + ترجمه فارسی

Methotrexate-bestatin interaction: Involvement of P-glycoprotein and organic anion transporters in rats

Keywords: تعامل دارو و دارو; MTX; methotrexate; DDI; drug-drug interaction; P-gp; P-glycoprotein; OAT; organic anion transporter; MRP; multidrug resistance-associated protein; BCRP; breast cancer resistance protein; OATP; organic anion transporting polypeptide; KRB; Krebs-Ringer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetic Interaction Between Rosuvastatin and Metformin in Healthy Korean Male Volunteers: A Randomized, Open-label, 3-period, Crossover, Multiple-dose Study

Keywords: تعامل دارو و دارو; Drug-drug interaction; metformin; pharmacokinetics; rosuvastatin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling

Keywords: تعامل دارو و دارو; AUC; area under the plasma concentration-time curve; DDI; drug-drug interaction; CLint; intrinsic clearance; BCRP; Breast Cancer Resistance Protein; HEK293; Human Embryonic Kidney 293 (cell-line); MRP; Multidrug resistance-associated protein; NTCP; Sodi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetic Interaction Between Rosuvastatin and Olmesartan: A Randomized, Open-label, 3-period, Multiple-dose Crossover Study in Healthy Korean Male Subjects

Keywords: تعامل دارو و دارو; drug-drug interaction; olmesartan; pharmacokinetics; rosuvastatin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetic Interaction Between Rosuvastatin and Telmisartan in Healthy Korean Male Volunteers: A Randomized, Open-label, Two-period, Crossover, Multiple-dose Study

Keywords: تعامل دارو و دارو; drug-drug interaction; pharmacokinetics; rosuvastatin; telmisartan;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of Hydrochlorothiazide on the Pharmacokinetics, Pharmacodynamics, and Tolerability of Canagliflozin, a Sodium Glucose Co-transporter 2 Inhibitor, in Healthy Participants

Keywords: تعامل دارو و دارو; canagliflozin; diuretic; drug-drug interaction; hydrochlorothiazide; pharmacodynamics; pharmacokinetics; sodium glucose co-transporter 2 (SGLT2) inhibitor; type 2 diabetes mellitus;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes

Keywords: تعامل دارو و دارو; Sanguinarine; Human liver microsomes; Cytochrome P450 enzyme; Drug-drug interaction; Time-dependent inhibition;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model

Keywords: تعامل دارو و دارو; Geniposide (PubChem CID: 107848); Borneol (PubChem CID: 64685); Muscone (PubChem CID: 10947); Geniposide; Blood-brain barrier; Borneol; Muscone; MDCK; Drug-drug interaction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The exposure of highly toxic aconitine does not significantly impact the activity and expression of cytochrome P450 3A in rats determined by a novel ultra performance liquid chromatography-tandem mass spectrometric method of a specific probe buspirone

Keywords: تعامل دارو و دارو; Aconitine; CYP3A; Buspirone; Drug-drug interaction; UPLC-MS/MS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Clopidogrel and the possibility of drug-drug interaction in primary health care

Keywords: تعامل دارو و دارو; Amlodipine; Atorvastatin; Clopidogrel; Drug-drug interaction; Omeprazole;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Three-dimensional Quantitative Structure-Activity Relationship Analysis of Inhibitors of Human and Rat Cytochrome P4503A Enzymes

Keywords: تعامل دارو و دارو; 3D-QSAR; CYP3A1; CYP3A4; drug inhibition; drug-drug interaction; structure-based CoMFA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities

Keywords: تعامل دارو و دارو; Farnesyl transferase inhibitor; Preclinical hepatic metabolism; Drug-drug interaction; Cytochrome P450;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Interaction of the antiviral drug telaprevir with renal and hepatic drug transporters

Keywords: تعامل دارو و دارو; OCT; MATE1; Telaprevir; OATP; Drug-drug interaction; Drug transporter;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Breast cancer among HIV infected individuals from the ONCOVIH study, in France: Therapeutic implications

Keywords: تعامل دارو و دارو; HIV infection; Breast cancer; ONCOVIH cross-sectional study; Drug-drug interaction; Cytochrome P450;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein

Keywords: تعامل دارو و دارو; AUC0-6 h; Area under the plasma concentration time curve from 0 to 6 h; B/P; Brain/Plasma; BSA; Bovine serum albumin; Cmax; Maximum drug concentration; CNS; Central nervous system; DDI; Drug-drug interaction; EPS; Extrapyramidal symptoms; FBS; Fetal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)

Keywords: تعامل دارو و دارو; ACN; anthocyanin; BCRP; breast cancer resistance protein; Cmax; maximum plasma concentration; CHO; Chinese hamster ovary; DDI; drug-drug interaction; ES; estrone sulfate; fu; fraction unbound in plasma; FDA; Food and Drug Administration; HEK; human embr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Induction of cytochrome P450 3A by Shexiang Baoxin Pill and its main components

Keywords: تعامل دارو و دارو; P450; cytochrome P450; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; TCM; traditional Chinese medicine; SBP; Shexiang Baoxin Pill; MDZ; midazolam; CHD; coronary heart diseases; MUS; muscone; TES; testosterone; GRf; ginsenoside Rf; GRg1; ginseno

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: A prospective cross-over drug-drug interaction study

Keywords: تعامل دارو و دارو; Irinotecan; Omeprazole; Drug-drug interaction; Pharmacokinetics; Toxicities; Neutropenia; Diarrhoea; CYP3A; UGT1A;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation

Keywords: تعامل دارو و دارو; ACN; acetonitrile; APAP; acetaminophen; CYP1A2; cytochrome P450 1A2 enzyme; CYP2B6; cytochrome P450 2B6 enzyme; CYP2C19; cytochrome P450 2C19 enzyme; CYP2D6; cytochrome P450 2D6 enzyme; CYP3A4; cytochrome P450 3A4 enzyme; CYP450; cytochrome P450 enzymes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Identification, Ki determination and CoMFA analysis of nuclear receptor ligands as competitive inhibitors of OATP1B1-mediated estradiol-17β-glucuronide transport

Keywords: تعامل دارو و دارو; OATP; CoMFA; Drug-drug interaction; Nuclear receptor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Drug-drug interactions of silymarin on the perspective of pharmacokinetics

Keywords: تعامل دارو و دارو; Drug-drug interaction; Milk thistle; Silymarin; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a “chemical knock-out equivalent” to assess the impact of efflux transporters on oral drug absorption in the rat

Keywords: تعامل دارو و دارو; MDR1; BCRP; CP-100,356; drug absorption; bioavailability; P450; efflux; drug-drug interaction;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Mechanism-based inhibition of cytochrome P450 enzymes: An evaluation of early decision making in vitro approaches and drug-drug interaction prediction methods

Keywords: تعامل دارو و دارو; AUC; area under the drug concentration (in the plasma) time profile; CYP; cytochrome P450; DDI; drug-drug interaction; FmCYP; the fraction of total drug metabolic clearance attributed to a single CYP; IC50; the concentration of inhibitor required to red

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

Proof of a 1-(3-chlorophenyl)piperazine (mCPP) intake-Use as adulterant of cocaine resulting in drug-drug interactions?

Keywords: تعامل دارو و دارو; 1-(3-Chlorophenyl)piperazine; mCPP; Drug-drug interaction; Drug metabolism; GC-MS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Prediction of the deleterious nsSNPs in ABCB transporters

Keywords: تعامل دارو و دارو; SNP; single nucleotide polymorphism; nsSNPs; non-synonymous SNPs; ABCB; ATP-binding cassette B; RPLS; ridge partial least square; LDA; linear discriminant analysis; 3D; 3-dimensional; SIFT; sorting intolerant from tolerant; ΔΔG; relative stability chang

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Propofol metabolism is enhanced after repetitive ketamine administration in rats: the role of cytochrome P-450 2B induction

Keywords: تعامل دارو و دارو; anaesthetics, i.v., ketamine; anaesthetics, propofol; drug-drug interaction; i.v., enzymes, cytochrome P-450; rat;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Thermodynamically based profiling of drug metabolism and drug-drug metabolic interactions: A case study of acetaminophen and ethanol toxic interaction

Keywords: تعامل دارو و دارو; Computational model; Drug metabolism; Drug-drug interaction; Network thermodynamics; Acetaminophen hepatotoxicity;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Drug-drug interaction between diclofenac, cetirizine and ranitidine

Keywords: تعامل دارو و دارو; Drug-drug interaction; Diclofenac sodium; Cetrizine dihydrochloride; Ranitidine hydrochloride; Thermal studies; Charge transfer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Statins' dosage in patients with renal failure and cyclosporine drug-drug interactions in transplant recipient patients

Keywords: تعامل دارو و دارو; HMG-CoA reductase inhibitors; Cyclosporine; Drug dosage adjustment; Renal insufficiency; Drug-drug interaction;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه