Keywords: E2F1; Memory; β-Amyloid; Flow cytometry; FISH; DNA content;
مقالات ISI (ترجمه نشده)
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Keywords: 3-AP; 3-aminopyridine-2-carboxaldehyde thiosemicarbazone; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; AMP/ADP/ATP; adenosine mono-, di-, and tri-phosphate; BLM; Bloom syndrome RecQ helicase-like; BRAF; V-raf mu
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody
Keywords: ANOVA; analysis of variance; BrdU; 5-bromo-2â²-deoxyuridine; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN2A; CDKN inhibitor 2A; CE; coefficient of error; CV; coefficient of variation; D; day; E2F1; E2F transcription factor 1; FOXM1; Forkhead box pr
High NUSAP1 expression predicts poor prognosis in colon cancer
Keywords: AJCC; American Joint Committee on Cancer; CI; confidential interval; CRC; colorectal cancer; DFS; disease free survival; E2F1; E2F transcription factor 1; FAM101B; family with sequence similarity 101 member B; HR; hazard ratio; MPE; molecular pathological
PPM1B depletion in U2OS cells supresses cell growth through RB1-E2F1 pathway and stimulates bleomycin-induced cell death
Keywords: PPM1B; RB1; E2F1; p38; Apoptosis;
Plasma microRNA signature of patients with IgA nephropathy
Keywords: IgAN; Immunoglobulin A nephropathy; miRNAs; microRNAs; NC; normal control; qRT-PCR; quantitative reverse transcription polymerase chain reaction; ROC; receiver operating characteristic curve; AUC; areas under the curve; ESRD; end-stage renal disease; eGFR
Non-genomic mechanisms of protein phosphatase 2A (PP2A) regulation in cancer
Keywords: CIP2A; SET; PME-1; MAPK; JAK2; ERK; PPP2R1A; PPP2R2A; PPP2R5A; PPP2R5C; MYC; TP53; E2F1; AKT; Feedback;
Loss of circadian protein TIMELESS accelerates the progression of cellular senescence
Keywords: TIMELESS; E2F1; Senescence;
E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes
Keywords: Gluconeogenesis; E2F1; Liver metabolism; Hyperglycemia; Diabetes; Cell cycle regulators; PCK1; Phosphoenolpyruvate carboxykinase 1; G6PC; glucose-6-phosphatase G6PC; PTT; Pyruvate tolerance test; CDK4; cyclin-cyclin-dependent kinase 4; PKA; protein kina
Nemo-like kinase (NLK) primes colorectal cancer progression by releasing the E2F1 complex from HDAC1
Keywords: NLK; E2F1; HDAC1; Cell cycle; Colorectal cancer;
Identification and characterization of two novel alternatively spliced E2F1 transcripts in the rat CNS
Keywords: CNS; central nervous system; NPAS3; neuronal per-arnt-sim domain protein 3; NMD; nonsense-mediated mRNA decay; PTBP; polypyrimidine tract binding proteins; PSD-95; postsynaptic density-95; TDP-43; TAR DNA-binding protein-43; qPCR; quantitative real-time P
Investigation of miR-136-5p key target genes and pathways in lung squamous cell cancer based on TCGA database and bioinformatics analysis
Keywords: LUSC; lung squamous cell cancer; TCGA; the Cancer Genome Atlas; GTEx; genotype-tissue expression; UGT1A1; UDP glucuronosyltransferase family 1 member A1; UGT1A3; UDP glucuronosyltransferase family 1 member A3 UGT1A6 UDP glucuronosyltransferase family 1 me
A pilot study of the modulation of sirtuins on arylamine N-acetyltransferase 1 and 2 enzymatic activity
Keywords: Ac-INH; acetyl-Isoniazid; Ac-PABA; acetyl-p-aminobenzoic acid; APC; allophycocyanin; CHO; Chinese hamster ovary cells; DMEM; Dulbecco's modified Eagle's medium; E2F1; E2F transctriptios factor 1; ER81; ETS-related protein 81; FITC; fluorescein IsoTioCyana
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Regulation and biological roles of the multifaceted miRNA-23b (MIR23B)
Keywords: miRNAs; MicroRNAs; C9orf3; Chromosome 9 Open Reading Frame 3; pri-miRNAs; primary miRNA; pre-miRNAs; precursor miRNAs; miRISC; miRNA-induced silencing complex; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; ACTA2; smooth muscle α-actin; MYH
Resveratrol suppresses doxorubicin-induced cardiotoxicity by disrupting E2F1 mediated autophagy inhibition and apoptosis promotion
Keywords: Doxorubicin; Cardiotoxicity; Resveratrol; Apoptosis; Autophagy; E2F1;
Coordinate regulation by transcription factors and DNA methylation in the core promoter region of SIRT6 in bovine adipocytes
Keywords: SIRT6; Promoter; Transcriptional regulation; DNA methylation; Bovine; Adipocyte; qPCR; real-time quantitative; CEBPβ; CCAAT enhancer binding protein beta; PAX6; paired box 6; KLF2; Kruppel-like factor 2; CMYB; myb proto-oncogene protein; NRF1; nuclear re
NFYB-induced high expression of E2F1 contributes to oxaliplatin resistance in colorectal cancer via the enhancement of CHK1 signaling
Keywords: Colorectal cancer (CRC); Oxaliplatin resistance; E2F1; NFYB; CHK1; CRC; Colorectal cancer; NFYB; Nuclear transcription factor Y subunit beta; E2F1; E2F transcription factor 1; CHK1; Checkpoint kinase 1; OR-CRC; Oxaliplatin-resistant CRC; DDR; DNA damage r
Juvenile hormone promotes locust fat body cell polyploidization and vitellogenesis by activating the transcription of Cdk6 and E2f1
Keywords: Juvenile hormone; Cdk6; E2f1; Endocycle; Polyploidy; Vitellogenesis;
microRNA-136 inhibits proliferation and promotes apoptosis and radiosensitivity of cervical carcinoma through the NF-κB pathway by targeting E2F1
Keywords: microRNA-136; E2F1; NF-κB signaling pathway; Cervical carcinoma; Radiosensitivity; Proliferation; Apoptosis;
Novel combined Ato-C treatment synergistically suppresses proliferation of Bcr-Abl-positive leukemic cells in vitro and in vivo
Keywords: Arsenic trioxide; Cisplatin; Combination therapy; Bcr-Abl-positive leukemia; Apoptosis; APL; acute promyelocytic leukemia; ATO; arsenic trioxide; Ato-C; ATO/CDDP; CDDP; Cisplatin; CI; combination index; DRI; dose-reduction index; CML; Chronic myelogenous
ReviewMuch more than you expected: The non-DHFR-mediated effects of methotrexate
Keywords: ADA; adenosine deaminase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ALL; acute lymphoblastic leukemia; ATIC; AICAR transformylase; ATRA; all-trans retinoic acid; DHF; dihydrofolate; DHFR; dihydrofolate reductase; E2F1; E2F transcription factor
Melanoma antigen-A11 regulates substrate-specificity of Skp2-mediated protein degradation
Keywords: Androgen receptor; Melanoma antigen-A11; MAGE-A11; Skp2; Cyclin A; E2F1; MAGE-A11; melanoma-antigen-A11; AR; androgen receptor; shRNA; short hairpin RNA; Skp2; S phase kinase-associated protein; SCF; Skp1-Cullin1-F-box; cdk; cyclin-dependent kinase; R1881
Dissecting the role of the elongation factor 1A isoforms in hepatocellular carcinoma cells by liposome-mediated delivery of siRNAs
Keywords: siRNA; eEF1A1; eEF1A2; HCC; E2F1; Liposome delivery;
Galactosylated polyaspartamide copolymers for siRNA targeted delivery to hepatocellular carcinoma cells
Keywords: Polyplexes; HCC; siRNA; E2F1; PHEA-DETA-PEG-GAL;
Original ArticlemiR-218 suppresses gastric cancer cell cycle progression through the CDK6/Cyclin D1/E2F1 axis in a feedback loop
Keywords: miR-218; E2F1; CDK6; Cyclin D1; Gastric cancer;
Temporal remodeling of the cell cycle accompanies differentiation in the Drosophila germline
Keywords: FUCCI; Oogenesis; Germline stem cell; CycB; E2f1; Cul4; CRL4; Cell cycle;
LPE-1, an orally active pyrimidine derivative, inhibits growth and mobility of human esophageal cancers by targeting LSD1
Keywords: LSD1; histone lysine specific demethylase 1; ESCC; esophageal squamous cell carcinoma; E2F1; E2F transcription factor; FAD; flavin adenine dinucleotide; ERBB2; epidermal growth factor receptor 2; CCNA2; cyclin-A2; NSCLC; non-small cell lung cancer; PHLDB2
Transcriptional regulation of BMCC1 mediated by E2F1 in neuroblastoma cells
Keywords: BMCC1/PRUNE2; E2F1; Cell cycle; Neuroblastoma;
E2F1-CDK1 pathway activation in kanamycin-induced spiral ganglion cell apoptosis and the protective effect of CR8
Keywords: Cochlear; Spiral ganglion cells; Apoptosis; E2F1; CDK1; CR8;
BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells
Keywords: ASXL1; additional sex combs-like 1; BAP1; BRCA1 associated protein-1; BRCA1; breast cancer gene 1; CSC; cancer stem cells (CSC); DTB; double thymidine block; DUB; deubiquitinating enzyme; E2F1; E2F transcription factor 1; FOXK; the forkhead transcription
Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia
Keywords: Azoospermia; E2F1; infertility; NOA; cryptorchidism; array comparative genomic hybridization (aCGH); copy number variations (CNV);
Impairment of the Pin1/E2F1 axis in the anti-proliferative effect of bortezomib in hepatocellular carcinoma cells
Keywords: Liver cancer; Proteasome inhibitor; Pin1; E2F1; Cell cycle; Huh7
Research ArticleA CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients
Keywords: HCC; hepatocellular carcinoma; HBV; hepatitis B virus; E2F1; E2F transcription factor 1; EZH2; enhancer of zeste homolog 2; PRC2; polycomb repressive complex 2; H3K27me3; trimethylation of lysine 27 at histone H3; AR; androgen receptor; CCRK; cell cycle-r
CD133+ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: Significance for melanoma treatment
Keywords: Melanoma; CSC; CAPE; E2F1; CD133; MAP kinase;
E2F1 promote the aggressiveness of human colorectal cancer by activating the ribonucleotide reductase small subunit M2
Keywords: Ribonucleotide reductase small subunit M2; E2F1; Colorectal cancer; Transactivation;
Synergistic cooperation of MDM2 and E2F1 contributes to TAp73 transcriptional activity
Keywords: MDM2; TAp73; Synergistic effect; E2F1;
miR-223: An inflammatory oncomiR enters the cardiovascular field
Keywords: AAA; Abdominal Aortic Aneurysm; AML; Acute Myeloid Leukemia; Apo-E KO; Apolipoprotein-E Knock-Out; C/EBP; CCAAT-Enhancer-Binding Proteins; CKD; Chronic Kidney Disease; D-HF; Diabetic Heart-Failure; DMD; Duchenne Muscular Dystrophy; E2F1; E2F transcription
The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells
Keywords: HCC; hepatocellular carcinoma; HBXIP; hepatitis B X-interacting protein; SCG3; Secretogranin III; E2F1; E2F transcription factor 1; NF-κB; nuclear factor kappa B; 3â²UTR; 3'untranslated region; MTT; methylthiazolyldiphenyl-tetrazolium bromide; EdU; et
Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic
Keywords: Signaling; E2F1; Non-linear motif; Feedback loop; Chemoresistance; Cancer
miR-223 inhibits dengue virus replication by negatively regulating the microtubule-destabilizing protein STMN1 in EAhy926Â cells
Keywords: Dengue virus; miR-223; STMN1; C/EBPα; E2F1;
Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity
Keywords: p53; Ubiquitylation; Oligomerization; Transcription; Proteasome; OD; Oligomerization Domain; Bax; Bcl2-associated X protein; Bcl-XL; B-cell lymphoma-extralarge; PUMA; p5pregulated Modulator of Apoptosis; Noxa; Noxious stress induced protein; Bid; BH3 inte
E2F1-regulated DROSHA promotes miR-630 biosynthesis in cisplatin-exposed cancer cells
Keywords: E2F1; DROSHA; miR-630; miRNA processing; Genotoxic stress;
Arsenic-induced Aurora-A activation contributes to chromosome instability and tumorigenesis
Keywords: Arsenic; Aurora-A; Centrosome; E2F1; Bladder; Skin;
E2F1 activates p53 transcription through its distal site and participates in apoptosis induction in HPV-positive cells
Keywords: E2F1; p53; Apoptosis; ChIP;
Original Full Length ArticleE2F1 effects on osteoblast differentiation and mineralization are mediated through up-regulation of frizzled-1
Keywords: Frizzled homology1 (FZD1); E2F1; Osteoblasts; Mineralization;
Scientific evidence for traditional claim of anti-obesity activity of Tecomella undulata bark
Keywords: ANOVA; analysis of variance; C/EBPα; CCAAT/enhancer binding protein alpha; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; EATUB; ethyl acetate extract of Tecomella undulata bark; E2F1; transcription factor; FBS; fetal bovine serum; FCS
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
Keywords: AGRP; agouti-related protein; AMPK; AMP-activated protein kinase; AP-1; activator protein-1; BCL10; B-cell lymphoma/leukemia-10; CIITA; class II, major histocompatibility complex, transactivator; DHA; docosahexaenoic acid; E2F1; transcription factor E2F1;
p53 Suppresses E2F1-dependent PLK1 expression upon DNA damage by forming p53-E2F1-DNA complex
Keywords: PLK1; p53; E2F1; Transcription regulation; DNA damage;