
In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome
Keywords: aLQTS; drug-induced or acquired long-QT syndrome; AP; action potential; APD; action potential duration; APD90; action potential duration at 90% repolarization; C1; closed state 1; C2; closed state 2; C3; closed state 3; EAD; early-afterdepolarization; ECG