Efavirenz treatment causes arterial stiffening in apolipoprotein E-null mice
Keywords: efavirenz; HAART; Efavirenz; Atherosclerosis; Arterial stiffening; Vascular remodeling;
مقالات ISI efavirenz (ترجمه نشده)
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CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B6*9 and CYP2B6*18 distribution in HIV-exposed subjects from Dschang, Western Cameroon
Keywords: efavirenz; CYP2B6; Efavirenz; Nevirapine; Pharmacogenetics; Poor metabolisers; Cameroon;
Correlation between microstructure and bioequivalence in Anti-HIV Drug Efavirenz
Keywords: efavirenz; EFV; Efavirenz; HAART; High Activity Antiretroviral Therapy; WPPM; Whole Powder Pattern Modelling; UNAIDS; United Nations Program on HIV/AIDS; HIV-1; human immunodeficiency virus type 1; BCS; Biopharmaceutical Classification System; API; active pharmaceut
Molecularly imprinted nanoparticles prepared by miniemulsion polymerization as a sorbent for selective extraction and purification of efavirenz from human serum and urine
Keywords: efavirenz; Molecularly imprinted polymer; Nanoparticles; Efavirenz; Human serum; Urine
Design of a novel crosslinked HEC-PAA porous hydrogel composite for dissolution rate and solubility enhancement of efavirenz
Keywords: efavirenz; Hydrogel composite; Physical crosslinking; Efavirenz; Rheology; Dissolution rate; Oral solubility
Mechanisms of cell death pathway activation following drug-induced inhibition of mitochondrial complex I
Keywords: efavirenz; Sirt3; Efavirenz; Complex I inhibition; Mitochondria; Peroxynitrite; Drug-induced liver injury (DILI)CBA, coumarin-7-boronic acid; CYP, cytochrome P450; CypD, cyclophilin D; ETC, electron transport chain; Fe-TCP, Fe(III) tetrakis(4-carboxyphenyl) porphyri
Synthesis and biological evaluation of pyridinone analogues as novel potent HIV-1 NNRTIs
Keywords: efavirenz; HIV; human immunodeficiency virus; NNRTIs; non-nucleoside reverse transcriptase inhibitors; SARs; structure and activity relationships; HAART; highly active antiretroviral therapy; RT; reverse transcriptase; NVP; nevirapine; DLV; delavirdine; EFV; efavire
Formulation and development of bicontinuous nanostructured liquid crystalline particles of efavirenz
Keywords: efavirenz; Liquid crystal; Cubosomes; Monoolein; Efavirenz; Cubic phase; Sustained release;
The phenolic metabolites of the anti-HIV drug efavirenz: Evidence for distinct reactivities upon oxidation with Frémy's salt
Keywords: efavirenz; Efavirenz; Phenolic metabolites; Oxidation; Quinone-imine; Quinoline; Anti-HIV drug; CYP; cytochrome P450; EFV; efavirenz; ESI; electrospray ionization; HIV; human immunodeficiency virus type 1; HPLC-DAD; high performance liquid chromatography with diod
CYP2B6 haplotype and biological factors responsible for hepatotoxicity in HIV-infected patients receiving efavirenz-based antiretroviral therapy
Keywords: efavirenz; HIV; Tuberculosis; CYP2B6; Efavirenz; Antiretroviral therapy
Pharmaceutical NanotechnologyAnti HIV nanoemulsion formulation: Optimization and in vitro-in vivo evaluation
Keywords: efavirenz; Nanoemulsion; Efavirenz; Condensation method; Phase inversion composition;
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: a systematic review and meta-analysis
Keywords: efavirenz; HIV; Tuberculosis; Rifampin; Nevirapine; Efavirenz
Effect of antiretroviral drugs on the DNA damage in mice
Keywords: efavirenz; Antiretroviral drugs; Efavirenz; Nevirapine; Micronucleus test; Comet assay; DNA damage
PedVacc 002: A phase I/II randomized clinical trial of MVA.HIVA vaccine administered to infants born to human immunodeficiency virus type 1-positive mothers in Nairobi
Keywords: efavirenz; Modified vaccinia virus Ankara (MVA); Infant vaccine trial in Africa; Exposed-uninfected infants; HIV-1; Pediatric HIV-1 vaccines; KEPI vaccines; EPI vaccines; rMVA; recombinant modified vaccinia virus Ankara; HIV-1; human immunodeficiency virus type 1; H
The role of genetic polymorphisms in cytochrome P450 and effects of tuberculosis co-treatment on the predictive value of CYP2B6 SNPs and on efavirenz plasma levels in adult HIV patients
Keywords: efavirenz; Efavirenz; HIV; Plasma level; Predictive value; SNP; Tuberculosis
Epidemiology and impact of HIV coinfection with Hepatitis B and Hepatitis C viruses in Sub-Saharan Africa
Keywords: efavirenz; 3TC; Lamivudine; AOR; Adjusted Odds Ratio; ADV; adefovir; ALT; alanine transaminase; Anti-HBcAb; antibody to Hepatitis B core antigen; Anti-HBeAb; antibody to Hepatitis B e-antigen; Chronic hepatitis B; persistence of HBsAg >6months; d4T; Stavudine; ddI;
Nanomedicines in the future of pediatric therapy
Keywords: efavirenz; ACTs; artemisinin combined therapies; ALN; alendronate; ANMAT; Administración Nacional de Medicamentos, Alimentos y TecnologÃa Médica; ARV; antiretrovirals; AS; antisense; AUC; area-under-the-curve; BMS; burning mouth syndrome; CD; cytosine deaminase;
Effects of concurrent administration of efavirenz on the disposition kinetics of amodiaquine in healthy volunteers
Keywords: efavirenz; Amodiaquine; Desethylamodiaquine; Efavirenz; Interactions;
Research ArticleER stress in human hepatic cells treated with Efavirenz: Mitochondria again
Keywords: efavirenz; ER; endoplasmic reticulum; UPR; unfolded protein response; PI; protease inhibitor; HIV1; human immunodeficiency virus 1; HCV; hepatitis C virus; EFV; efavirenz; cART; combined antiretroviral therapy; ÎΨm; mitochondrial membrane potential; ROS; reactive
Mecanismo de acción y farmacocinética de rilpivirina
Keywords: efavirenz; Efavirenz; Farmacocinética; Inhibidores no nucleósidos de la transcriptasa inversa; RilpivirinaEfavirenz; Pharmacokinetics; Nonnucleoside reverse transcriptase inhibitor; Rilpivirine
The role of competitive binding to human serum albumin on efavirenz–warfarin interaction: a nuclear magnetic resonance study
Keywords: efavirenz; Drug–drug interactions; Drug–protein binding; Efavirenz; Human serum albumin; NMR; Warfarin
Quantitative analysis of the effect of zidovudine, efavirenz, and ritonavir on insulin aggregation by multivariate curve resolution alternating least squares of infrared spectra
Keywords: efavirenz; Insulin aggregation; Zidovudine; Efavirenz; Ritonavir; Multivariate curve resolution alternating least squares; FTIR; 1H NMR spectroscopy
Datos de rilpivirina en pacientes naïve. Lecciones de los estudios ECHO, THRIVE y STaR
Keywords: efavirenz; Tratamiento antirretroviral de inicio; Naïve; Rilpivirina; Efavirenz; Inhibidores de la transcriptasa inversa no; análogos de nucleósidos; Eficacia; Seguridad; ResistenciasRilpivirine; Efavirenz; NNRTI; NRTI; Efficacy; Safety; Virological failure; Resista
Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Efavirenz
Keywords: efavirenz; efavirenz; absorption; Biopharmaceutics Classification System (BCS); permeability; regulatory science; solubility;
Agonism of human pregnane X receptor by rilpivirine and etravirine: Comparison with first generation non-nucleoside reverse transcriptase inhibitors
Keywords: efavirenz; Rilpivirine; Etravirine; Efavirenz; Nevirapine; Delavirdine; Pregnane X receptor
Biochemical effects of chronic administration of efavirenz on the intracranial auditory relay centers of adult Wistar rats
Keywords: efavirenz; biochemical effects; efavirenz; inferior colliculus; medial geniculate body; Wistar rats
NNRTIs: Future prospects
Keywords: efavirenz; Efavirenz; NNRTI; NevirapineÉfavirenz; INNTI; Névirapine
Oropharyngeal yeast colonization in HIV-infected outpatients in southern Taiwan: CD4 count, efavirenz therapy and intravenous drug use matter
Keywords: efavirenz; Antifungal susceptibility; Candida dubliniensis; efavirenz; human immunodeficiency virus; yeast colonization
RP-HPLC method for simultaneous estimation of tenofovir disoproxil fumarate, lamivudine, and efavirenz in combined tablet dosage form
Keywords: efavirenz; Efavirenz; lamivudine; RP-HPLC; tenofovir disoproxil fumarate; validation;
Development and evaluation of a thermosensitive vaginal gel containing raltegravir + efavirenz loaded nanoparticles for HIV prophylaxis
Keywords: efavirenz; Raltegravir; Efavirenz; Pre-exposure prophylaxis; Nanoparticles; HIV; Thermosensitive gel;
Changes in Patient-reported Neuropsychiatric Outcomes during the SENSE Trial: First-line Treatment with Two Nucleoside Analogues plus Etravirine or Efavirenz
Keywords: efavirenz; AIDS; Antiretroviral treatment; Efavirenz; Etravirine; HIV; Nervous system; Nonnucleosides; Nucleoside analogues; Psychiatric; Quality of life
Hepatic safety of efavirenz in HIV/hepatitis C virus-coinfected patients with advanced liver fibrosis
Keywords: efavirenz; HIV; Hepatitis C; Liver fibrosis; Cirrhosis; Efavirenz; Transaminase elevations
Study on the structure and vibrational spectra of efavirenz conformers using DFT: Comparison to experimental data
Keywords: efavirenz; Efavirenz; IR; Raman spectroscopy; HOMO; LUMO
High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba
Keywords: efavirenz; ART; antiretroviral therapy; CI; confidence interval; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside RTI; PI; protease inhibitor; FCR; full-class resistance; CRF; circulating recombinant form; HIV; human immunodeficiency virus; MD
NNRTIs: Pharmacological data
Keywords: efavirenz; Efavirenz; Nevirapine; HIV reservoirÉfavirenz; Névirapine; Réservoir VIH
Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz
Keywords: efavirenz; EFV; Efavirenz; HAART; highly active antiretroviral therapy; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside reverse transcriptase inhibitor; ROS; reactive oxygen species; ÎΨm; mitochondrial transmembrane potential; DNA; polymera
Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors
Keywords: efavirenz; Combinatorial design; Diversity selection HIV-1; NNRTIs HEPT; Antiviral activity; RHHROCXXJZOAGP-UHFFFAOYSA-N; KMCGFILCIRJEHJ-UHFFFAOYSA-N; XXFUGXPQNOZBIR-UHFFFAOYSA-N; OFOHDLYVTOWSFB-UHFFFAOYSA-N; PWAKKEPZIWJVBA-UHFFFAOYSA-N; DTCUBSJAMNGQFU-UHFFFAOYSA-N;
Morphological effects of chronic efavirenz administration on the kidney of adult Wistar rats
Keywords: efavirenz; efavirenz; kidney; morphological effects; Wistar rats
Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat
Keywords: efavirenz; Abcg2; Efavirenz; Hiv; Oral bioavailability; Intestine;
Simultaneous determination of efavirenz, rifampicin and its metabolite desacetyl rifampicin levels in human plasma
Keywords: efavirenz; HPLC–UV; SPE; Efavirenz; Rifampicin; Desacetyl rifampicin; Plasma
Effects of nevirapine and efavirenz on human adipocyte differentiation, gene expression, and release of adipokines and cytokines
Keywords: efavirenz; Lipodystrophy; Adipocyte; Nevirapine; Efavirenz; Non-nucleoside analog reverse transcriptase inhibitor; Adipokine
Ãtude des métatrajectoires des taux de CD4 par taxonomie dans la réponse du régime antirétroviral à base d'éfavirenz chez des patients naïfs symptomatiques à Abidjan
Keywords: efavirenz; Ãfavirenz; Réponse antirétrovirale; Taux de CD4; Métatrajectoires; Modèle non hiérarchique descendant; Efavirenz; Antiretroviral response; CD4 cells count; Meta-trajectories; Nonhierarchical-descendant model;
Quantum chemical and experimental studies on the structure and vibrational spectra of efavirenz
Keywords: efavirenz; Efavirenz; DFT; HF; Optimized geometries; ESP
Determination of salivary efavirenz by liquid chromatography coupled with tandem mass spectrometry
Keywords: efavirenz; Efavirenz; Saliva; LC–MS/MS
Alteration of pharmacokinetics of proguanil in healthy volunteers following concurrent administration of efavirenz
Keywords: efavirenz; Proguanil; Pharmacokinetic interaction; Cycloguanil; Efavirenz
Similar antiviral efficacy and tolerability between efavirenz and lopinavir/ritonavir, administered with abacavir/lamivudine (Kivexa®), in antiretroviral-naïve patients: A 48-week, multicentre, randomized study (Lake Study)
Keywords: efavirenz; Efavirenz; Lopinavir/ritonavir; Kivexa®; Randomized study; Efficacy; Tolerability
Xenotropic murine leukemia virus-related virus is susceptible to AZT
Keywords: efavirenz; XMRV; AZT; 3TC; Tenofovir; D4T; Ritonavir; Indinavir; Saquinavir; 118-D-24; Efavirenz
Non-nucleoside reverse transcriptase inhibitor efavirenz increases monolayer permeability of human coronary artery endothelial cells
Keywords: efavirenz; Efavirenz; HAART; Endothelial permeability; Tight junction protein; Oxidative stress; Antioxidant; Ginkgolide B; MnTBAP; JNK; NFκB;
A highly sensitive ultra performance liquid chromatography–tandem mass spectrometric (UPLC–MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma
Keywords: efavirenz; Seminal plasma; Efavirenz; UPLC–MS/MS; Blood plasma; Electrospray ionization (ESI); HIV/AIDS
Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)
Keywords: efavirenz; NNRTI; Efavirenz; Nevirapine; Etravirine; Rilpivirine; Next generation NNRTI