دانلود مقالات ISI درباره Egfr + ترجمه فارسی

Cdc42 induces EGF receptor protein accumulation and promotes EGF receptor nuclear transport and cellular transformation

Keywords: EGFR; epidermal growth factor receptor; Small GTP-binding protein; γCOP of coatomer protein complex; MAP kinases; EGF receptor; Cell transformation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleTwenty-eight day safety, antiviral activity, and pharmacokinetics of tenofovir alafenamide for treatment of chronic hepatitis B infection

Keywords: CHB; chronic hepatitis B; HBsAg; hepatitis B surface antigen; TDF; tenofovir disoproxil fumarate; TFV; tenofovir; TAF; tenofovir alafenamide; TFV-DP; tenofovir diphosphate; PBMC; peripheral blood mononuclear cells; eGFR; estimated glomerular filtration ra

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewChemoprevention targets for tobacco-related head and neck cancer: Past lessons and future directions

Keywords: Chemoprevention; Head and neck cancer; Oral premalignant lesion; Retinoid; COX-2; EGFR; Phytochemical; Green tea; Sulforaphane;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The challenge of blocking a wider family members of EGFR against head and neck squamous cell carcinomas

Keywords: Afatinib; Personalised therapy; EGFR; ErbB; TKI; HPV; EBV; P16; Head and neck squamous cell carcinoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Potential of overcoming resistance to HER2-targeted therapies through the PI3K/Akt/mTOR pathway

Keywords: Everolimus; Breast cancer; mTOR; HER2; Resistance; AE; adverse event; Akt; protein kinase B; CI; confidence interval; CBR; clinical benefit rate; DLT; dose-limiting toxicities; EGFR; epidermal growth factor receptor; HER2; human epidermal growth factor re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors

Keywords: ATP; adenosine 5′-triphosphate; CML; chronic myeloid leukemia; EGFR; epidermal growth factor receptor; FC; flash chromatography; GIST; gastrointestinal stromal tumor; MAPK; mitogen activated protein kinase; PDGFR; platelet-derived growth factor receptor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Role of lipid microdomains in TLR-mediated signalling

Keywords: ABCA1/G1; ATP-binding cassette, sub-family A/G, member 1; AP-1; activator protein 1; CARC; inverted “CRAC” domain; CD 14/36/55; cluster of differentiation 14/36/55; CRAC; cholesterol recognition amino-acid consensus sequence; CXCR4; C-X-C chemokine re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Lapatinib versus lapatinib plus capecitabine as second-line treatment in human epidermal growth factor receptor 2-amplified metastatic gastro-oesophageal cancer: A randomised phase II trial of the Arbeitsgemeinschaft Internistische Onkologie

Keywords: Gastric cancer; HER2; EGFR; Lapatinib;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Multicenter evaluation of a new progastrin-releasing peptide (ProGRP) immunoassay across Europe and China

Keywords: NSCLC; non-small-cell lung cancer; SCLC; small-cell lung cancer; NSE; neuron-specific enolase; ProGRP; progastrin-releasing peptide; NET; neuroendocrine tumors; MCT; medullary carcinoma of the thyroid; PUMCH; Peking Union Medical College Hospital; SST; se

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Chimeric ubiquitin ligases inhibit non-small cell lung cancer via negative modulation of EGFR signaling

Keywords: NSCLC; EGFR; Ubiquitination; Targeted therapy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells

Keywords: Non-small cell lung cancer; Invasion; ROCK; EGFR; Y-27632; Afatinib;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor

Keywords: LRR; Leucine-rich repeats; LRIG3; Leucine-rich repeats and immunoglobulin-like domains; EGFR; Epidermal growth factor receptor; PI3K; Phosphatidylinositol 3-kinase; ERK; Extracellular signal-regulated kinases; MTT; Methyl thiazolyl tetrazolium; TUNEL; Ter

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Tumoral CD10 expression correlates with high-grade histology and increases risk of recurrence in patients with stage I lung adenocarcinoma

Keywords: ATS; American Thoracic Society; CIR; cumulative incidence of recurrence; CT; computed tomography; EGFR; epidermal growth factor receptor; ERS; European Respiratory Society; HPF; high-power fields; HR; hazard ratio; IASLC; International Association for the

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

A comparison of non-biologically active truncated EGF (EGFt) and full-length hEGF for delivery of Auger electron-emitting 111In to EGFR-positive breast cancer cells and tumor xenografts in athymic mice

Keywords: Breast cancer; Indium-111; EGF; EGFR; Radiopharmaceuticals; Theranostics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Spen is required for pigment cell survival during pupal development in Drosophila

Keywords: Retina; Spitz; EGFR; Apoptosis; Drosophila;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Aldosterone stimulates the cardiac sodium/bicarbonate cotransporter via activation of the g protein-coupled receptor gpr30

Keywords: Ald; aldosterone; NHE-1; Na+/H+ exchanger; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; MPG; N-(2-mercapto-propionyl)glycine; ROS; reactive oxygen species; NBC; Na+/HCO3− cotransporter; Apo; apocynin; Wort; wortmannin; eple; epl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Assessment of the impact of manufacturing changes on the physicochemical properties and biological activity of Her1-ECD vaccine during product development

Keywords: Comparability studies; Recombinant protein; EGFR; Mass spectrometry; HPLC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS

Keywords: Axon growth; Spinal cord injury; PP2A; EGFR; CRMP2; Y307 phosphorylation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Phase 1 dose-escalation study of S-222611, an oral reversible dual tyrosine kinase inhibitor of EGFR and HER2, in patients with solid tumours

Keywords: Protein kinase inhibitor; Phase 1 clinical trial; EGFR; HER2; HER4;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The aryl hydrocarbon receptor (AhR) mediates resistance to apoptosis induced in breast cancer cells

Keywords: AhR; aryl hydrocarbon receptor; ER; estrogen receptor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; MNF; 3′methyl-4′nitroflavone; COX-2; cyclooxygenase-2; IDO; indoleamine 2, 3-dioxygenase; Kyn; kynurenine; MNF; 3′methoxy-4′nitroflavone; TGFα; tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The role of AGR2 and AGR3 in cancer: Similar but not identical

Keywords: AGR2; AGR3; PDI family; Cancer; AA; amino acids; ALS; familial amyotrophic lateral sclerosis; AGR; anterior gradient; AhR; aryl hydrocarbon receptor; AR; androgen receptor; CAPN8; calpain 8; CAPN9; calpain 9; CDDP; cisplatin; CFTR; cystic fibrosis transme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular characterization of a disintegrin and metalloprotease-17 (ADAM17) in granulosa cells of bovine preovulatory follicles

Keywords: LH; luteinizing hormone; hCG; human chorionic gonadotropin; COC; cumulus-oocyte complex; PTGS2; prostaglandin synthase 2; TNFAIP6; tumor necrosis factor-alpha-induced protein 6; EGFR; epidermal growth factor receptor; EREG; epiregulin; AREG; amphiregulin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Andrographolide decreased VEGFD expression in hepatoma cancer cells by inducing ubiquitin/proteasome-mediated cFos protein degradation

Keywords: Andro; Andrographolide; VEGFD; Vascular endothelial growth factor D; ELISA; Enzyme-linked immunosorbent assay; AP-1; Activator protein-1; JNK; c-Jun N-terminal kinase; MAPK; Mitogen-activated protein kinase; VEGF; Vascular endothelial growth factor; MMP2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Interactions of the EGFR juxtamembrane domain with PIP2-containing lipid bilayers: Insights from multiscale molecular dynamics simulations

Keywords: EGFR; Juxtamembrane domain; PIP2; Molecular dynamics; Lipid bilayer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cooperation of distinct Rac-dependent pathways to stabilise E-cadherin adhesion

Keywords: Cadherin; Rac; EGFR; DOCK180; GEF;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Variant of BCL3 gene is strongly associated with five-year survival of non-small-cell lung cancer patients

Keywords: BCL3; B-cell CLL/lymphoma 3; NSCLC; non-small-cell lung cancer; RelA; v-rel avian reticuloendotheliosis viral oncogene homolog A; RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; c-Rel; v-rel avian reticuloendotheliosis viral oncogene hom

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers

Keywords: Cytokine; Estrogen; Sex hormone; SIAH1; SIAH2; ACK1/TNK2; activated CDC42-associated kinase 1; AR; androgen receptor; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia mutated related; BF; biochemical failure; DCC; deleted in colorectal cance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ShcC proteins: Brain aging and beyond

Keywords: ShcC adaptor proteins; Signaling; Aging; Brain ischemia; Brain tumors; Immunity; Aβ; beta-amyloid; AD; Alzheimer's disease; Akt; protein kinase B (PKB); ALK; anaplastic lymphoma kinase (receptor tyrosine kinase); APP; alpha-amyloid precursor protein; ARD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ERBB3 is required for tumor promotion in a mouse model of skin carcinogenesis

Keywords: EGFR; ERBB3; Mouse; Skin; Carcinogenesis; Wound healing

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer

Keywords: Colorectal cancer; EGFR; KRAS; Synthetic lethality; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

EGFR and NF-κB: partners in cancer

Keywords: EGFR; gefitinib; erlotinib; NF-κB; resistance; tumor-initiating cells

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cetuximab directly inhibits P-glycoprotein function in vitro independently of EGFR binding

Keywords: ABC transporter; ATP-binding cassette transporter; ABCB1; ATP-binding cassette, sub-family B, member 1 (=P-gp gene); ATP; adenosine triphosphate; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EGFR; epidermal growth factor rec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer

Keywords: Colorectal cancer; Cancer stem cell; Wnt signaling; Traf2- and Nck-interacting kinase (TNIK); Molecular targeting therapy; ABC; ATP-binding cassette; APC; adenomatous polyposis coli; CBP; cAMP response element binding protein (CREB)-binding protein; CK; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Requirement of ERα and basal activities of EGFR and Src kinase in Cd-induced activation of MAPK/ERK pathway in human breast cancer MCF-7 cells

Keywords: Cadmium; Breast cancer cells; ERα; MAPK/ERK; EGFR; Src kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cadmium at nanomolar concentrations activates Raf-MEK-ERK1/2 MAPKs signaling via EGFR in human cancer cell lines

Keywords: Cadmium; Endocrine disruption; EGFR; ERK1/2 MAPKs; Mdm2; p53;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Profiling of Oncogenic Driver Events in Lung Adenocarcinoma Revealed MET Mutation as Independent Prognostic Factor

Keywords: Lung cancer; EGFR; KRAS; ALK; HER2; BRAF; MET; ROS1; RIT1; TTF-1 lung adenocarcinoma; NRAS; Driver mutations; Oncogenic driver mutation; East Asian lung cancer; MET amplification; Targeted therapy; Genetic marker; Biomarker; Molecular classification lung

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Alteration of major vault protein in human glioblastoma and its relation with EGFR and PTEN status

Keywords: EGFR; epidermal growth factor receptor; EGFRvIII; EGFR variant III mutation; FISH; fluorescent in situ hybridization; GBM; glioblastoma; GFAP; glial fibrillary acidic protein; HPFs; high-power fields; KPS; Karnofsky performance status; MLPA; multiplex lig

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Allelic variations in the CYBA gene of NADPH oxidase and risk of kidney complications in patients with type 1 diabetes

Keywords: ACE; angiotensin converting enzyme; ANCOVA; analysis of covariance; ANOVA; analysis of variance; AOPP; advanced oxidation protein products; CI; confidence intervals; eGFR; estimated glomerular filtration rate; ESRD; end-stage renal disease; GENEDIAB; Gén

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives

Keywords: C; Cytosine; DNMT; DNA methyl transferase; BER; Base Excision Repair; NER; Nucleotide Excision Repair; TET; Ten Eleven Translocation protein; 5mC; 5methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; ESC; Embryo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)

Keywords: CAR; constitutive androstane receptor; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor (ErbB-1, ERBB, HER1); ELK1; transcription factor, a member of ETS oncogene family; ERK; mitogen-activated protein kinases 1 and 3 (MAPK1 and 3); LB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

NEDD4: The founding member of a family of ubiquitin-protein ligases

Keywords: RING; Really Interesting New Gene; HECT; Homologous to E6-AP C-Terminus; Ndfip1; Nedd4 family interacting protein 1; AMPARs; alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptors; EGFR; epidermal growth factor receptor; FGFR1; Fibroblast gro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Epithelial cell ADAM17 activation by Helicobacter pylori: role of ADAM17 C-terminus and Threonine-735 phosphorylation

Keywords: Helicobacter pylori; ADAM 17; Phosphorylation; EGFR; HB-EGF; TNF-α;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewPharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer

Keywords: ALDH; aldehyde dehydrogenase; ALK; anaplastic lymphoma kinase; BRAF; v-Raf murine sarcoma viral oncogene homolog B1; CSC; cancer stem cell; EGFR; epidermal growth factor receptor; EGFR-TKIs; EGFR tyrosine kinase inhibitors; EGFRvIII; EGFR variant III; EML

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of DOR prevents remifentanil induced postoperative hyperalgesia through regulating the trafficking and function of spinal NMDA receptors in vivo and in vitro

Keywords: ACSF; artificial cerebral spinal fluid; DOR; delta opioid receptor; DRG; dorsal root ganglion; EGFR; epidermal growth factor receptor; GSK-3β; glycogen synthase kinase-3β; mEPSC; miniature excitatory postsynaptic current; NMDA; N-methyl-d-aspartate; OIH

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

KRAS Status as an Independent Prognostic Factor for Survival after Yttrium-90 Radioembolization Therapy for Unresectable Colorectal Cancer Liver Metastases

Keywords: CEA; carcinoembryonic antigen; CI; confidence interval; CRC; colorectal cancer; EGFR; epidermal growth factor receptor; KRAS; Kirsten rat sarcoma viral oncogene homolog; OS; overall survival; wt; wild-type; 90Y; yttrium-90;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Troponin T as a Predictor of End-Stage Renal Disease and All-Cause Death in African Americans and Whites From Hypertensive Families

Keywords: cTnT; cardiac troponin T; eGFR; estimated glomerular filtration rate; ESRD; end-stage renal disease; GENOA; Genetic Epidemiology Network of Arteriopathy; HR; hazard ratio; hsCRP; high-sensitivity C-reactive protein;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Advanced targeted nanomedicine

Keywords: bFGF; basic fibroblast growth factor; EGFR; epidermal growth factor receptor; DGLs; dendrigraft poly-l-lysines; DPPC; 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; DSPC; 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; EuL; europium luminescent; HER; hum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Current and Future Approaches in the Management of Non–Small-Cell Lung Cancer Patients With Resistance to EGFR TKIs

Keywords: Afatinib; EGFR; NSCLC; Oligoprogressive; T790M

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma

Keywords: LC-MS/MS; Human liver microsomes; Non-small cell lung cancer; EGFR; Tyrosine kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Studies for development of novel quinazolinones: New biomarker for EGFR

Keywords: Quinazolinones; EGFR; Docking; CADD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه