Attenuation of reperfusion injury by renal ischemic postconditioning: The role of NO
Keywords: Ischemic postconditioning; Kidney; Ischemia; NO; eNOS; iNOS; ET-1;
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Neuronal nitric oxide mediates cerebral vasodilatation during acute hypertension
Keywords: ACh; acetylcholine; aCSF; artificial cerebrospinal fluid; AP; arterial pressure; CBF; cerebral blood flow; CVR; cerebrovascular resistance; Diam; diameter; eNOS; endothelial nitric oxide synthase; HR; heart rate; i.v.; intravenous; MAP; mean AP; NMDA; N-m
No evidence for modulation of endothelial nitric oxide synthase by the olive oil polyphenol hydroxytyrosol in human endothelial cells
Keywords: Hydroxytyrosol; Olive oil; Nitric oxide; eNOS; Atherosclerosis
Effect of demethylasterriquinone b1 in hypertension associated vascular endothelial dysfunction
Keywords: ACh; acetylcholine; ANOVA; analysis of variance; CMC; carboxy methyl cellulose; DAQ B1; demethylasterriquinone B1; DMSO; dimethyl sulfoxide; DOCA; desoxycortisone acetate; eNOS; endothelial nitric oxide synthase; MABP; mean arterial blood pressure; NBT; n
Role of eNOS phosphorylation at Ser-116 in regulation of eNOS activity in endothelial cells
Keywords: Nitric oxide; eNOS; Phosphorylation; Protein–protein interactions
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: Changes in expression of NADPH oxidase subunits and eNOS
Keywords: Oxidative stress; NADPH oxidase; eNOS; Diabetes
Calcium-activated potassium channel and connexin expression in small mesenteric arteries from eNOS-deficient (eNOS−/−) and eNOS-expressing (eNOS+/+) mice
Keywords: eNOS; Connexin; Calcium-activated potassium channels; Nitric oxide; EDHF (endothelium-derived hyperpolarizing factor); Small mesenteric arteries
Measurement of plasma nitrite by chemiluminescence without interference of S-, N-nitroso and nitrated species
Keywords: ASC; ascorbic acid; A.U.; arbitrary units; CV; coefficient variation; eNOS; endothelial nitric oxide synthase; NO; nitric oxide; HNO2; nitrous acid; NO+; nitrosonium cation; KI; potassium iodide; I2; iodine; I3â; triiodide; RNNOs; N-nitrosamines; RSNOs;
Endothelial Nitric Oxide Synthase Keeps Erection Regulatory Function Balance in the Penis
Keywords: eNOS; Erectile dysfunction; Nitric oxide; Priapism; PKG; RhoA; Rho-kinase
Increased cerebral and renal endothelial nitric oxide synthase gene expression after cardiopulmonary bypass in the rat
Keywords: 1; 7; 19; 25; 29; cDNA; complementary DNA; CPB; cardiopulmonary bypass; eNOS; endothelial nitric oxide synthase; IP; intraperitoneal; IV; intravenous; nNOS; neuronal nitric oxide synthase; NOS; nitric oxide synthase; PCR; polymerase chain reaction; RT-PCR
Asymmetric Dimethylarginine Determines the Improvement of Endothelium-Dependent Vasodilation by Simvastatin
Keywords: ADMA; asymmetric dimethylarginine; eNOS; endothelial nitric oxide synthase; FMD; flow-mediated dilation; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; LDL; low-density lipoprotein; NO; nitric oxide; SR; sustained release;
HSF1 and constitutively active HSF1 improve vascular endothelial function (heat shock proteins improve vascular endothelial function)
Keywords: HSF1; Heat shock protein; Endothelium; PAI-1; Endothelin-1; eNOS; Thrombomodulin
Alterations of intracellular calcium concentration and nitric oxide generation in pulmonary artery endothelium after subarachnoid hemorrhage of the rabbit
Keywords: Subarachnoid hemorrhage; Impaired NO generation; Pulmonary endothelium; eNOS; Endothelial intracellular calcium concentration
Splenic hemodynamics and decreased endothelial nitric oxide synthase in the spleen of rats with liver cirrhosis
Keywords: Spleen; Splenic hemodynamics; eNOS; Liver cirrhosis; Portal hypertension
Anti-brain cholinergic auto antibodies from primary Sjögren syndrome sera modify simultaneously cerebral nitric oxide and prostaglandin biosynthesis
Keywords: Antibodies; Sjögren syndrome; mAChR; Prostaglandin E2; COX-1 mRNA; COX-2 mRNA; Nitric oxide synthase; eNOS; nNOS
Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat
Keywords: Statin; Resveratrol; Cholesterol; Myocardium; Akt; eNOS; VEGF; β-Catenin
Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
Keywords: eNOS; Nitric oxide synthase; Phosphorylation; Nitric oxide; Endothelium; Hsp90
Trimetazidine improves post-ischemic recovery by preserving endothelial nitric oxide synthase expression in isolated working rat hearts
Keywords: Trimetazidine; Endothelial function; Nitric oxide; Ischemia; Reperfusion injury; eNOS
A cell-based nitric oxide reporter assay useful for the identification and characterization of modulators of the nitric oxide/guanosine 3′,5′-cyclic monophosphate pathway
Keywords: Nitric oxide; cGMP; CNG channel; eNOS; Soluble guanylyl cyclase
Research ReportPharmacological induction of heat shock protein exerts neuroprotective effects in experimental intracerebral hemorrhage
Keywords: GGA; geranylgeranylacetone; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's modified Eagle's medium; eNOS; endothelial nitric oxide synthase; HSF1; heat shock factor-1; HSP; heat shock protein; ICH; intracerebral hemorrhage; IL-6; interleukin-6; MIP-1; macroph
Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: Implication for the gender difference in cardiac arrhythmias
Keywords: Long QT syndrome; Gender; Ion channel; Nitric oxide; eNOS; Sex hormoneAF-1, activation domain-1; AF-2, activation domain-2; AF-3, activation domain-3; APD, action potential duration; AR, androgen receptor; carboxy-PTIO, 2-(4-carboxyphenyl)-4,5-dihydro-4,4
Docosahexaenoic acid affects endothelial nitric oxide synthase in caveolae
Keywords: Polyunsaturated fatty acids; Caveolae; Fatty acid composition; Phospholipids; eNOS
Kinase inhibitors for cardiovascular disease
Keywords: β-ARs; β-adrenergic receptors; AM; adrenomedullin; Ang II; angiotensin II; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CVDs; cardiovascular diseases; CHF; congestive heart failure; CAD; coronary artery disease; ET-1; endothelin-1; eNOS; endothe
Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo
Keywords: AgIIR; angiotensin II receptor; cAMP; cyclic adenosine monophosphate; EC; endothelial cells; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptor; IGFR; insulin-like growth factor receptor;
Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea
Keywords: OHCs; outer hair cells; [Ca2+]i, intracellular Ca2+ concentrations; TRPV4; transient receptor potential vanilloid 4; NO; nitric oxide; nitric oxide synthase; NOS; nNOS; neuronal nitric oxide synthase; eNOS; endothelial nitric oxide synthase; IHCs; inner h
Inducible Nitric Oxide Synthase From Bone Marrow-Derived Cells Plays a Critical Role in Regulating Colonic Inflammation
Keywords: BM; bone marrow; DSS; dextran sodium sulfate; eNOS; endothelial nitric oxide synthase; iNOS; inducible NOS; KGF; keratinocyte growth factor; MPO; myeloperoxidase; nNOS; neuronal NOS; TNBS; trinitrobenzene sulfonic acid;
Rapid effects of diesel exhaust particulate extracts on intracellular signaling in human endothelial cells
Keywords: Endothelial cells; Diesel exhaust; AKT; eNOS; Estrogen; Estrogen receptor;
Murine Pre-Eclampsia Induced by Unspecific Activation of the Immune System Correlates with Alterations in the eNOS and AT1 Receptor Expression in the Kidneys and Placenta
Keywords: Pre-eclampsia; Murine model; eNOS; AT1R; Th1 cell; Hypertension;
Palmitoylation of the TPβ isoform of the human thromboxane A2 receptor.
Keywords: AR; adrenergic receptor; C-tail; carboxyl-terminal tail; [Ca2+]i; intracellular calcium; eNOS; endothelial nitric oxide synthase; GFP; green fluorescent protein; GPCR; G protein-coupled receptor; HA; hemagglutinin; HEK; human embryonic kidney; 5-hydroxytr
Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair
Keywords: amyotrophic lateral sclerosis; ataxia-telangiectasia-like disorder; Werner syndrome; xeroderma pigmentosum; nitric oxide synthase; superoxide dismutase; AfXPB; Archaeoglobus fulgidus XPB; AH; autoinhibitory helix; ALS; amyotrophic lateral sclerosis; ATL
Mice lacking the gene encoding for MMP-9 and resistance artery reactivity
Keywords: Metalloproteinases; Microcirculation; Pressure; Myogenic tone; Shear stress; eNOS
Phosphodiesterase type 5 inhibitor sildenafil citrate does not potentiate the vasodilative properties of nebivolol in rat aorta
Keywords: Nebivolol; Sildenafil; PDE5; Vasodilation; Erectile dysfunction; eNOS
Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells
Keywords: Nitric oxide; eNOS; Pomegranate juice
Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects with coronary artery disease and controls
Keywords: eNOS; Risk factors; Coronary artery disease; Gene polymorphism
Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells
Keywords: Histone deacetylase; Sp1; eNOS; Gene expression; TSA
Serine 1179 phosphorylation of endothelial nitric oxide synthase caused by 2,4,6-trinitrotoluene through PI3K/Akt signaling in endothelial cells
Keywords: TNT; PI3K; Akt; eNOS; Phosphorylation; Hydrogen peroxide; Endothelial cell
Signaling pathways involving the sodium pump stimulate NO production in endothelial cells
Keywords: Na+,K+-ATPase; Ouabain; Signaling cascade; Akt; eNOs; PI3K
Hypoxia-induced upregulation of endothelial small G protein RhoA and Rho-kinase/ROCK2 inhibits eNOS expression
Keywords: Rho-kinase; Enos; Endothelial cell; RhoA; siRNA;
Disruption of caveolin-1 leads to enhanced nitrosative stress and severe systolic and diastolic heart failure
Keywords: Caveolin; eNOS; Nitric oxide; Cardiac contractility and hemodynamics
Insulin resistance in nondiabetic patients with acute myocardial infarction
Keywords: Acute myocardial infarction; eNOS; Insulin resistance; Leptin; Stress hormones
Quantifying the l-arginine paradox in vivo
Keywords: eNOS; l-Arginine; Laser Doppler flowmetry; Nitric oxide; PO2
Role of lipid rafts in ceramide and nitric oxide signaling in the ischemic and preconditioned hearts
Keywords: Lipid rafts; Caveolin; Ceramide; Sphingosine-1-phosphate; Nitric oxide; eNOS; Heart; Ischemia/reperfusion
Nicotiflorin reduces cerebral ischemic damage and upregulates endothelial nitric oxide synthase in primarily cultured rat cerebral blood vessel endothelial cells
Keywords: Nicotiflorin; Neuroprotection; Ischemia–reperfusion; Hypoxia–reoxygenation; eNOS; Cerebrovascular endothelial cell
ENOS is not activated by nebivolol in human failing myocardium
Keywords: eNOS; Nebivolol; Carvedilol; Metoprolol; Heart failure; BRL 37344
Early determinants of H2O2-induced endothelial dysfunction
Keywords: BAECs; bovine aortic endothelial cells; BH2; 7,8-dihydrobiopterin; BH4; tetrahydrobiopterin; CMH; 1-hydroxy-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine; ESR; electron spin resonance; eNOS; endothelial nitric oxide synthase; L-NAME; NÏ-nitro-L-argini
Polyenylphosphatidylcholine pretreatment protects rat liver from ischemia/reperfusion injury
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; DLPC; dilinoleoylphosphatidylcholine; eNOS; endothelial NO synthase; GSH; reduced glutathione; iNOS; inducible NO synthase; I/R; ischemia/reperfusion; LDL; low-density lipoprotein; MDA; malon
Inflammatory responses of the substantia nigra after acute hypoxia in neonatal rats
Keywords: IGF; IGFBP-3; IGFBP-5; eNOS; nNOS; iNOS; GFAP; Substantia nigra; Hypoxia
High-dose atorvastatin is associated with impaired myocardial angiogenesis in response to vascular endothelial growth factor in hypercholesterolemic swine
Keywords: 16; 17; 23; 29; ADP; adenosine 5â²-diphosphate; ANOVA; analysis of variance; eNOS; endothelial nitric oxide synthase; FGF-2; basic fibroblast growth factor; ILM; isotope-labeled microsphere; NO; nitric oxide; SNP; sodium nitroprusside; VEGF; vascular end
Endothelial nitric oxide synthase gene variant modulates the relationship between serum cholesterol levels and blood pressure in the general population: New evidence for a direct effect of lipids in arterial blood pressure
Keywords: eNOS; Blood pressure; Cholesterol; Genetics; Polymorphism
Activation of endothelial nitric oxide synthase by cilostazol via a cAMP/protein kinase A- and phosphatidylinositol 3-kinase/Akt-dependent mechanism
Keywords: Nitric oxide; eNOS; Endothelial cells; Akt; PKA; Cilostazol