Design, synthesis, and biological evaluation of anti-EV71 agents
Keywords: Enterovirus 71; 3C protease inhibitor; Michael acceptor
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Inhibition of enterovirus VP4 myristoylation is a potential antiviral strategy for hand, foot and mouth disease
Keywords: Human enterovirus; EV71; Myristoylation; HFMD; Antiviral; HFMD; hand, foot and mouth disease; EV71; Enterovirus 71; RD; Rhabdomyosarcoma; DMEM; Dulbecco's modified Eagle's medium; F-12; Ham's F12 nutrient mix; FBS; fetal bovine serum; MOI; multiplicity of
Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds
Keywords: Enterovirus D68; Enterovirus 71; Rhinovirus 87; Picornavirus; Antiviral;
Enterovirus 71 inhibits cellular type I interferon signaling by inhibiting host RIG-I ubiquitination
Keywords: Enterovirus 71; Type I interferon; RIG-I; Ubiquitination
MOV10 interacts with Enterovirus 71 genomic 5â²UTR and modulates viral replication
Keywords: Enterovirus 71; MOV10; IRES; Cloverleaf-like structure; Processing body;
Preparation of quaternary amine monolithic column for strong anion-exchange chromatography and its application to the separation of Enterovirus 71
Keywords: Monolithic column; Strong anion-exchange chromatography; Enterovirus 71; Quaternary amine;
Establishment of an animal challenge model as a potency assay for an inactivated Enterovirus Type 71 vaccine
Keywords: Enterovirus 71; Animal challenge model; Potency assay; Formalin-inactivated EV71 vaccine; Reference EV71 antisera;
A novel inactivated enterovirus 71 vaccine can elicit cross-protective immunity against coxsackievirus A16 in mice
Keywords: Enterovirus 71; Coxsackievirus A16; Vaccine; Chimeric virus; Neutralizing epitope;
Genetic characterization of Enterovirus 71 strains circulating in Vietnam in 2012
Keywords: Enterovirus 71; C4 subgenogroup; Vietnam; Phylogenetics; Outbreak;
The nuclear protein Sam68 is recruited to the cytoplasmic stress granules during enterovirus 71 infection
Keywords: Enterovirus 71; Sam68; Stress granules; RNA-binding proteins
Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Keywords: HFMD; hand, foot and mouth disease; 3Cpro; 3C proteinase; EV71; enterovirus 71; HRV; human rhinovirus; NMR; nuclear magnetic resonance; RP-HPLC; reverse phase-high pressure liquid chromatography; TFA; trifluoroacetic acid; LC; liquid chromatography; MS; m
Modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71
Keywords: N6-benzyladenosine derivatives; Synthesis and antiviral activity; SAR; Enterovirus 71;
Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71
Keywords: Grifola frondosa polysaccharide; Chemical properties; Antiviral; Enterovirus 71; Viral replication;
Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16
Keywords: Hand foot and mouth disease; Capsid binding; Drug resistance; Fitness; VP1 pocket; VP1; Viral Protein 1; IC50; Half-maximal inhibitory concentration; CC50; Half maximal cytotoxic concentration; TCID50; Half-maximal tissue culture infective dose; PV; polio
RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT
Keywords: Enterovirus 71; RASSF4; AKT phosphorylation; Replication;
TIA-1 and TIAR interact with 5′-UTR of enterovirus 71 genome and facilitate viral replication
Keywords: Enterovirus 71; 5′-UTR; RNA binding proteins; TIA-1; TIAR
Neuroimaging of HFMD infected by EV71
Keywords: Hand Foot and Mouth Disease; Enterovirus 71; Neuroimaging
Pros and cons of VP1-specific maternal IgG for the protection of Enterovirus 71 infection
Keywords: Enterovirus 71; VP1; Maternal IgG; Protective immunity; Pre-existing immunity;
Magnesium lithospermate B and rosmarinic acid, two compounds present in Salvia miltiorrhiza, have potent antiviral activity against enterovirus 71 infections
Keywords: Enterovirus 71; Internal ribosome entry site; Magnesium lithospermate B; Rosmarinic acid; Salvia miltiorrhiza; VP-1 proteins; Magnesium lithospermate B (PubChem CID: 6918234); Sodium danshensu (PubChem CID: 23711819); Rosmarinic acid (PubChem CID: 528179)
High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice
Keywords: Enterovirus 71; Virus-like particle; Vaccine; Pichia pastoris; Oral infection;
Development of a Specific Latex Agglutination Test to Detect Antibodies of Enterovirus 71
Keywords: Enterovirus 71; Hand-foot-and-mouth disease; Latex agglutination test; Homogeneity; Ethyl-dimethyl-amino-propyl carbodiimide
A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice
Keywords: Enterovirus 71; Norovirus P particle; Neutralizing antibody; Epitope; Antigen presentation;
Development of EV71 virus-like particle purification processes
Keywords: Enterovirus 71; Vaccine; Virus-like particle; Chromatography; Purification; Downstream processing;
Yakammaoto inhibits enterovirus 71 infection by reducing viral attachment, internalization, replication, and translation
Keywords: Antiviral; Enterovirus 71; She-Gan-Ma-Huang-Tang; Ye-Gan-Ma-Huang-Tang
Pyrrolidine dithiocarbamate inhibits enterovirus 71 replication by down-regulating ubiquitin–proteasome system
Keywords: Enterovirus 71; Pyrrolidine dithiocarbamate; Ubiquitin–proteasome system; Antioxidant; Apoptosis
Saururus chinensis (Lour.) Baill blocks enterovirus 71 infection by hijacking MEK1-ERK signaling pathway
Keywords: Saururus chinensis (Lour.) Baill; Enterovirus 71; MEK1; ERK; NF-κB; Antiviral;
Regulation of host responses and viral replication by the mitogen-activated protein kinases in intestinal epithelial cells infected with Enterovirus 71
Keywords: Enterovirus 71; Cytokine; MAPK; ERK; JNK; NF-κB
Fourteen types of co-circulating recombinant enterovirus were associated with hand, foot, and mouth disease in children from Wenzhou, China
Keywords: Enteroviruses; Enterovirus 71; Coxsackievirus A6; Recombination; Hand, foot and mouth disease;
Early growth response-1 facilitates enterovirus 71 replication by direct binding to the viral genome RNA
Keywords: 3â²UTR; 3â²-untranslated region; 5â²UTR; 5â²-untranslated region; CNS; central nervous system; Co-IP; co-immunoprecipitation; CPE; cytopathogenic effect; DMEM; Dulbecco's modified Eagle's medium; EGR1; early growth response-1; eIF4E; eukaryotic initia
Enterovirus 71 induces autophagy by regulating has-miR-30a expression to promote viral replication
Keywords: Enterovirus 71; Autophagy; miR-30a; Beclin-1; Viral replication;
Droplet digital PCR as a useful tool for the quantitative detection of Enterovirus 71
Keywords: Droplet digital PCR; Quantitative real-time PCR; Enterovirus 71; Hand, foot and mouth disease;
Development and evaluation of a real-time method of simultaneous amplification and testing of enterovirus 71 incorporating a RNA internal control system
Keywords: Enterovirus 71; Isothermal amplification; PCR-fluorescence probing assay;
Suramin inhibits EV71 infection
Keywords: Enterovirus 71; Suramin; Antiviral
Identification of specific antigenic epitope at N-terminal segment of enterovirus 71 (EV-71) VP1 protein and characterization of its use in recombinant form for early diagnosis of EV-71 infection
Keywords: Enterovirus 71; Hand, Foot and mouth disease; Viral capsid protein; Early diagnosis;
A combination vaccine comprising of inactivated enterovirus 71 and coxsackievirus A16 elicits balanced protective immunity against both viruses
Keywords: Enterovirus 71; Coxsackievirus A16; Bivalent vaccine; Neutralizing antibody; Passive protection;
Epidemiology of Enterovirus 71 Infections in Taiwan
Keywords: enterovirus 71; epidemiology; vaccine
The enteroviruses: Problems in need of treatments
Keywords: Enterovirus; Poliomyelitis; Poliovirus; Enterovirus 71; Neonatal; Antiviral therapy
Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers
Keywords: Enterovirus 71; Hand, foot and mouth disease; Enterovirus; Morpholino oligomers; Antiviral agent
In vitro inhibition of enterovirus 71 infection with a nickel ion/chitosan microcomposite
Keywords: Enterovirus 71; Microcomposite; Inhibition; Infection;
Peripheral T lymphocyte subset imbalances in children with enterovirus 71-induced hand, foot and mouth disease
Keywords: Hand, foot and mouth disease; Enterovirus 71; T cell subsets; Cytokines; Imbalance;
A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice
Keywords: Enterovirus 71; Coxsackievirus A16; Virus-like particle; Vaccine; Neutralizing antibody;
The role of enterovirus 71 and coxsackievirus A strains in a large outbreak of hand, foot, and mouth disease in 2012 in Changsha, China
Keywords: Hand; foot; and mouth disease; Etiology; Enterovirus 71; Coxsackievirus A
Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides
Keywords: Bioassay-guided counter-current chromatography; Folding fan mode; A. asphodeloides; Enterovirus 71; Structure–activity relationship
Construction of an infectious cDNA clone of Enterovirus 71: Insights into the factors ensuring experimental success
Keywords: Enterovirus 71; cDNA clone; Overlapping RT-PCR; Long distance RT-PCR; Poly(A) tail; In vitro RNA;
AUF1 is recruited to the stress granules induced by coxsackievirus B3
Keywords: Stress granule; AUF1; Coxsackievirus B3; Enterovirus 71; Picornavirus
Activation of PI3K/Akt pathway limits JNK-mediated apoptosis during EV71 infection
Keywords: Enterovirus 71; PI3K/Akt pathway; JNK; Apoptosis; ASK1
A 3Cpro-dependent bioluminescence imaging assay for in vivo evaluation of anti-enterovirus 71 agents
Keywords: Enterovirus 71; Split luciferase; 3C protease; In vivo imaging
Histopathological features and distribution of EV71 antigens and SCARB2 in human fatal cases and a mouse model of enterovirus 71 infection
Keywords: EV71; enterovirus 71; HFMD; hand, foot, and mouth disease; SCARB2; scavenger receptor class B, member 2; CNS; central nervous system; i.p; intraperitoneal; RD; rhabdomyosarcoma; Enterovirus 71; Hand; foot; and mouth disease; Pathology; Human cases; Mouse
The identification and characterization of nucleic acid chaperone activity of human enterovirus 71 nonstructural protein 3AB
Keywords: Enterovirus 71; RNA chaperone; RNA duplex unwinding; Replication; Antivirals strategies;
An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation
Keywords: Enterovirus 71; NITD008; Nucleoside analogue; Polymerase