Keywords: اثر EPR; Positron emission tomography; Kidney dysfunction; Tumor diagnosis; EPR effect; Nanomedicine;
مقالات ISI اثر EPR (ترجمه نشده)
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Keywords: اثر EPR; Ligand-functionalized liposomes; Dual-functionalized liposomes; EPR effect; Tumor heterogeneity; Targeted therapy; Nanomedicine;
Keywords: اثر EPR; Pretargeted imaging; Pretargeted radionuclide therapy; EPR effect; Nanomedicines; Bispecific antibody and hapten recognition; (strept)avidin-biotin interaction; Hybridization of complementary oligonucleotides; SPAAC; Tetrazine ligation;
Keywords: اثر EPR; Multidrug resistance; P-glycoprotein inhibitor; EPR effect; HPMA copolymer; Poly(propylene oxide); Micellar drug conjugate;
Keywords: اثر EPR; EPI; ,epirubicin; SA; sialic acid; TAMs; tumor-associated macrophages; SA-CH; sialic acid-cholesterol conjugate; EPI-S; EPI solution; EPI-CL; conventional liposomal EPI; EPI-PL; PEGylated liposomal EPI; EPI-SAL; SA-CH modified liposomal EPI; EPR effect; e
Keywords: اثر EPR; AHPP; 4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine; Apaf-1; Apoptotic protease activating factor 1; AsnPhePhe; Asparagine-phenylalanine-phenylalanine; D-(Asp)8; D-Aspartic acid peptide; D; Degradable; E; Enzymatic degradation; H; Hydrolytic degradation; EDT
Keywords: اثر EPR; Cancer treatment; EPR effect; Photodynamic therapy; Polymeric nanoparticles
Keywords: اثر EPR; 3D; three-dimensional; ACA; alkylcyanoacrylates; AETMAC; 2-acryloxyethyltrimethylammonium chloride; ATRP; atom transfer radical polymerization; AuNPs; gold nanoparticles; bFGF; basic fibroblast growth factor; BM-MSCs; bone marrow-derived mesenchymal stem
Keywords: اثر EPR; EPR effect; Paclitaxel; Polymeric micelles; Tumor targeting; Nanomedicine; Tumor vasculature;
Keywords: اثر EPR; Nanomedicine; EPR effect; Controlled drug release; Nanoparticle targeting; Cancer therapy;
Keywords: اثر EPR; Nanotherapeutics; EPR effect; PLD; Biomarker; Transport oncophysics;
Keywords: اثر EPR; Bu, bufalin; CS, chitosan; BCS, biotinylated chitosan; NPs, nanoparticles; EPR effect, enhanced permeability and retention effect; ROS, reactive oxygen speciesBufalin; Chitosan; Biotin; Tumor targeting; EPR effect; Apoptosis
Keywords: اثر EPR; 5-ALA; 5-amino-levulinic acid; RGD; arginine-glycine-aspartic acid; BBB; blood-brain barrier; BCNU; carmustine; CASANT; carmustine sustained-release implant; CNS; central nervous system; CED; convection-enhanced delivery; c(RGDyK); cyclic arginineâ
Keywords: اثر EPR; A2870; ovarian cancer cells; A2870cis; cisplatin resistant ovarian cancer cells; A549; lung cancer cells; ABRs; auditory brainstem responses; AUC; area under the curve; AuNP; gold nanoparticles; CDDP or cisplatin; cis-diamminedichloroplatinum(II); Cis-(ch
Keywords: اثر EPR; ET; edelfosine; ALPs; alkylphospholipids; LN; lipid nanoparticles; EPR effect; enhanced permeability and retention effect; ET-LN; edelfosine-loaded lipid nanoparticles; MCL; mantle cell lymphoma; PDI; polydispersity index; B-LN; blank (unloaded) nanoparti
Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy
Keywords: اثر EPR; Paclitaxel; Nanocarrier; Vitamin-E-TPGS; Nanoparticles (NP); Drug delivery; EPR effect;
Preparation of PEGylated liposomes incorporating lipophilic lomeguatrib derivatives for the sensitization of chemo-resistant gliomas
Keywords: اثر EPR; BBB; blood-brain barrier; Br-Cn; bromoalkane; Br-C12; 1-bromododecane; Br-C14; 1-bromotetradecane; Br-C16; 1-bromohexadecane; Br-C18; 1-bromooctadecane; CHOL; cholesterol; DCM; dichloromethane; DLS; dynamic light scattering; DMEM; Dulbecco's modified Ea
Long-term biodistribution study of HPMA-ran-LMA copolymers in vivo by means of 131I-labeling
Keywords: اثر EPR; EPR effect; HPMA; Imaging; Iodine-131; RAFT; Walker 256 mammary carcinoma;
Angiotensin-II regulates dosing time-dependent intratumoral accumulation of macromolecular drug formulations via 24-h blood pressure rhythm in tumor-bearing mice
Keywords: اثر EPR; Blood pressure; Circadian rhythm; EPR effect; Intratumoral accumulation; Liposome;
HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study
Keywords: اثر EPR; EPR effect; HPMA copolymer; Tumor-targeting; Tumor environment responsive; Stability; Arginine;
N-(2-hydroxypropyl)methacrylamide polymer conjugated pyropheophorbide-a, a promising tumor-targeted theranostic probe for photodynamic therapy and imaging
Keywords: اثر EPR; EPR effect; Polymeric micelles; Macromolecular photosensitizers; Tumor targeting; Pyropheoporbide-a; Singlet oxygen;
Liposome-chaperoned cell-free synthesis for the design of proteoliposomes: Implications for therapeutic delivery
Keywords: اثر EPR; ABC; accelerated blood clearance; AUC; area under the curve; BACE1; β-site APPcleaving enzyme 1; C8bp; C8-binding protein; Cardiolipin; 1,3-bis[1,2-dioleoyl-sn-glycero-3-phospho]-sn-glycerol; CDH2; N-cadherin; CF; cell-free; CHO; Chinese Hamster Ovary ce
Mini-reviewChallenges and opportunities for siRNA-based cancer treatment
Keywords: اثر EPR; RNA interference; Tumour; Nanoparticle; EPR effect; Endosome escape; Off-target;
Hydrophobically modified polysaccharide-based on polysialic acid nanoparticles as carriers for anticancer drugs
Keywords: اثر EPR; Polysialic acid; Nanoparticles; Targeted cancer therapy; EPR effect; Doxorubicin;
Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for HeLa and RAW264.7 cells, enhancing their photodamaging effect
Keywords: اثر EPR; DIC; 1,3-diisopropylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DLS; dynamic light scattering; DMAP; N,N-dimethyl-4-aminopyridine; DMF; N,N-dimethylformamide; DMEM; Dulbecco's Modified Eagle Medium; EPR effect; enhanced permeability and retention ef
Croconaine nanoparticles with enhanced tumor accumulation for multimodality cancer theranostics
Keywords: اثر EPR; Controlled assembly; Molecular nanoprobe; EPR effect; Multimodality imaging; Photothermal therapy;
Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate
Keywords: اثر EPR; Pirarubicin; PHPMA conjugate; Tandem-diblock PHPMA conjugate; EPR effect; Tumor drug targeting;
The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel
Keywords: اثر EPR; Drug delivery; HPMA; Doxorubicin; Docetaxel; EPR effect; Tumor microenvironment;
Challenges and strategies in anti-cancer nanomedicine development: An industry perspective
Keywords: اثر EPR; Nanomedicine; EPR effect; Clinical translation; Pre-clinical models; Industry; Companion diagnostics; Patient pre-selection;
Impact of surface grafting density of PEG macromolecules on dually fluorescent silica nanoparticles used for the in vivo imaging of subcutaneous tumors
Keywords: اثر EPR; NPs; nanoparticles; EPR; enhanced permeation and retention effect; i.v.; intravenous; RES; reticuloendothelial system; PEG; polyethylene glycol; FRI; fluorescence reflectance imaging; NIR; near infra-red; TEOS; Tetraethyl orthosilicate; MPS; (3-mercaptopr
pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect
Keywords: اثر EPR; Cisplatin; Styrene-maleic acid copolymer; Tumor environment-sensitive drug delivery; Tumor-selective drug delivery; EPR effect;
To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?
Keywords: اثر EPR; EPR effect; Tumor targeting; Nanomedicine; Drug delivery; Cancer;
Intra-tumor distribution of PEGylated liposome upon repeated injection: No possession by prior dose
Keywords: اثر EPR; Drug delivery system; PEGylated liposome; Intra-tumor distribution; EPR effect; Repeated injection;
Multifunctional envelope-type mesoporous silica nanoparticles for pH-responsive drug delivery and magnetic resonance imaging
Keywords: اثر EPR; pH-responsiveness; Drug delivery; Magnetic resonance imaging; EPR effect;
Targeted tumor theranostics using folate-conjugated and camptothecin-loaded acoustic nanodroplets in a mouse xenograft model
Keywords: اثر EPR; Folate receptor targeting; EPR effect; Camptothecin; Acoustic nanodroplet vaporization; Targeted tumor theranostics;
Phospholipid-stabilized mesoporous carbon nanospheres as versatile carriers for systemic delivery of amphiphobic SNX-2112 (a Hsp90 inhibitor) with enhanced antitumor effect
Keywords: اثر EPR; CNs; carbon nanospheres; MCNs; mesoporous carbon nanospheres; SN-PMCNs; SNX-2112-loaded MCNs stabilized by phospholipid; SN-Sol; SNX-2112 solution; EPR effect; enhanced permeability and retention effect; BCS; biopharmaceutics classification system; BCA; b
pH sensitive polymeric complex of cisplatin with hyaluronic acid exhibits tumor-targeted delivery and improved in vivo antitumor effect
Keywords: اثر EPR; CDDP; cisplatin; HA; hyaluronic acid; HA-CDDP; hyaluronic acid-cisplatin complex; EPR effect; enhanced permeability and retention effect; DDS; drug delivery system; SMA; styrene maleic acid copolymer; PEG; poly(ethylene glycol); HPMA; N-(2-Hydroxypropyl
Combination therapy with dendritic cell vaccine and IL-2 encapsulating polymeric micelles enhances intra-tumoral accumulation of antigen-specific CTLs
Keywords: اثر EPR; PEG; Polyethylene glycol; AUC; Area under the concentration-time curve; MRT; Mean residence time; EPR effect; Enhanced permeability and retention effect; Immunotherapy; Dendritic cells; Interleukin-2; Drug delivery system; Cytotoxic T lymphocytes;
Breakthrough discoveries in drug delivery technologies: The next 30Â years
Keywords: اثر EPR; Nanoparticles; EPR effect; Microneedles; Oncolytic viruses; Cell therapy; Microchips;
Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage
Keywords: اثر EPR; HPMA polymer conjugate; Pirarubicin (THP); Tumor selectivity; Acid-cleavable linkage; Hydrazone; EPR effect;
Enhanced Bacterial Tumor Delivery by Modulating the EPR Effect and Therapeutic Potential of Lactobacillus casei
Keywords: اثر EPR; EPR effect; Lactobacillus casei; nitroglycerin; vascular permeability; ACE inhibitor; Cancer; Nanotechnology; Permeability; Targeted drug delivery; Distribution;
Inhibition of ectopic glioma tumor growth by a potent ferrocenyl drug loaded into stealth lipid nanocapsules
Keywords: اثر EPR; ansa-FcdiOH; Nanomedicine; Cell cycle; EPR effect;
Polycation-based nanoparticles for RNAi-mediated cancer treatment
Keywords: اثر EPR; Nanoparticles; Cancer; RNAi; siRNA; EPR effect; Clinical translation;
Tumor delivery of Photofrin® by PLL-g-PEG for photodynamic therapy
Keywords: اثر EPR; Photodynamic therapy; Graft copolymer; Non-covalent complex; EPR effect;
Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo
Keywords: اثر EPR; Fluorescence imaging; Fluorescent nanoprobe; Singlet oxygen; Tumor targeting; HPMA-ZnPP conjugate; EPR effect;
Dendrimer space concept for innovative nanomedicine: A futuristic vision for medicinal chemistry
Keywords: اثر EPR; PK; pharmacokinetic; PD; pharmacodynamic; PK/PD; pharmacokinetic/pharmacodynamic; RES; reticuloendothelial system; EPR effect; enhanced permeability and retention effect; ADMET; absorption, distribution, metabolism, excretion and toxicity; logP; octanolâ
Premature drug release of polymeric micelles and its effects on tumor targeting
Keywords: اثر EPR; Polymeric micelles; Organ distribution; Bioimaging; Tumor accumulation; EPR effect; Premature release
A polyphosphoester conjugate of melphalan as antitumoral agent
Keywords: اثر EPR; Polymer-drug conjugate; EPR effect; Polyphosphoesters; Chemotherapeutics
Analysis on the current status of targeted drug delivery to tumors
Keywords: اثر EPR; Targeted drug delivery; Nanoparticles; EPR effect; Tumor; Cancer
PEGylation for drug delivery to ischemic myocardium: Pharmacokinetics and cardiac distribution of poly(ethylene glycol)s in mice with normal and ischemic myocardium
Keywords: اثر EPR; Poly(ethylene glycol); Pharmacokinetics; Cardiac distribution; EPR effect; Myocardial ischemia