Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
Keywords: FABP4; A-FABP; aP2; Antidiabetes; Antiobesity; Antiatherosclerosis;
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Herbalog: A tool for target-based identification of herbal drug efficacy through molecular docking
Keywords: Herbalog; Natural product; Virtual screening; Molecular docking; FABP4 inhibitor; Andrographis paniculata; CXCR4; C-X-C chemokine receptor type 4; RMSD; Root-mean square deviation; FABP4; Fatty acid binding protein 4; 1; 8-ANS, 1-Anilinonaphthalene-8-sulf
Altered CSNK1E, FABP4 and NEFH protein levels in the dorsolateral prefrontal cortex in schizophrenia
Keywords: Schizophrenia; Postmortem dorsolateral prefrontal cortex; Proteomics; CSNK1E; FABP4; NEFH;
Impact of epidermal fatty acid binding protein on 2D-NMR-assessed atherogenic dyslipidemia and related disorders
Keywords: FABP5; FABP4; Nuclear Magnetic Resonance; Atherogenic dyslipidaemia; Carotid plaque; hsCRP; Type 2 diabetes;
Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells
Keywords: Preeclampsia; miR-148a/152; DNMT1; FABP4; DNA methylation;
Hyperglycemia-induced PATZ1 negatively modulates endothelial vasculogenesis via repression of FABP4 signaling
Keywords: PATZ1; Diabetes; Endothelial cells; Angiogenesis; FABP4;
Transcriptional regulation analysis of FAM3A gene and its effect on adipocyte differentiation
Keywords: FAM3A; family with sequence similarity 3, member A; G6PD; glucose-6-phosphate dehydrogenase; PPARG(2); peroxisome proliferator-activated receptor gamma(2); C/EBPα; CCAAT/enhancer binding protein alpha; C/EBPβ(C/EBPβbeta); CCAAT/enhancer binding protein
Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors
Keywords: Lipolysis; Type 2 diabetes; Adipose tissue; Metabolism; Lipid storage; ADRA2A; adrenoreceptor alpha 2 A; AT; Adipose tissue; FABP4; Fatty acid binding protein 4; FASN; Fatty acid synthase; IRS1; Insulin receptor substrate-1; GLUT4 and SLC2A4; Glucose tran
Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition
Keywords: SNP; single nucleotide polymorphism; FABP3; fatty acid binding protein 3; HMGA1; high mobility group AT-hook 1; MC4R; melanocortin-4 receptor; IGF2; insulin-like growth factor-2; FABP4; fatty acid binding protein 4; QTL; quantitative trait locus; SFA; sat
FABP4 plasma concentrations are determined by acquired metabolic derangements rather than genetic determinants
Keywords: FABP4; FABP4 polymorphisms; Type 2 diabetes; Metabolic syndrome; Obesity;
Exposure to p,pâ²-DDE enhances differentiation of 3T3-L1 preadipocytes in a model of sub-optimal differentiation
Keywords: MTT; 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide; Actb; β-actin; BMI; body mass index; DDE; p,pâ²-dichlorodiphenyldichloroethylene; FABP4; fatty acid binding protein 4; Fasn; fatty acid synthase; Slc2a4; glucose transporter type 4; Lep;
Physical activity below the minimum international recommendations improves oxidative stress, ADMA levels, resting heart rate and small artery endothelial function
Keywords: Physical activity; Oxidative stress; Small artery endothelial function; ADMA; Actividad fÃsica; Estrés oxidativo; Función endotelial de pequeñas arterias; ADMA; PA; physical activity; METs/h/wk; hours/week at a given metabolic equivalent level; SOD; s
Research ArticleFatty acid binding protein-4 (FABP4) is a hypoxia inducible gene that sensitizes mice to liver ischemia/reperfusion injury
Keywords: ALT; alanine aminotransferase; ARNT; aryl hydrocarbon receptor nuclear translocator; AST; aspartate aminotransferase; ChIP; chromatin immunoprecipitation; EMSA; electrophoretic mobility shift assay; FABP4; fatty acid binding protein 4; GdCl3; gadolinium c
Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination
Keywords: FABP4; Inhibitor; Diabetes; Virtual screening; Crystal structure
Human FABP1 T94A variant enhances cholesterol uptake
Keywords: C/EBPα; CCAAT/enhancer binding protein alpha; CETP; cholesteryl ester transfer protein; CPT1A; carnitine palmitoyl transferase IA, liver; CPT2; carnitine palmitoyl-CoA transferase II; CVD; cardiovascular disease; FABP1; human liver fatty acid binding pro
Molecular and cellular pharmacologyIdentification and characterisation of a prototype for a new class of competitive PPARγ antagonists
Keywords: ANGPTL4; angiopoietin-like 4; AP-1; activator protein 1; aP2; adipocyte protein 2; CD36; cluster of differentiation 36; DMEM; Dulbecco׳s Modified Eagle׳s Medium; FABP4; fatty acid binding protein 4; FCS; foetal calf serum; FMOC-l-leucine; N-(9-fluorenyl
High-methionine diets accelerate atherosclerosis by HHcy-mediated FABP4 gene demethylation pathway via DNMT1 in ApoEâ/â mice
Keywords: AS; atherosclerosis; Hcy; homocysteine; HHcy; Hyperhomocysteinemia; ApoEâ/â; apolipoprotein E knockout; FABP4; fatty acid-binding protein 4; DNMT1; DNA methyltransferases 1; SAH; S-adenosylhomocysteine; SAM; S-adenosylmethionine; TC; total Cholesterol
Fatty Acid Binding Protein-4 is expressed in the mouse placental labyrinth, yet is dispensable for placental triglyceride accumulation and fetal growth
Keywords: FABP4; Trophoblast; Fetus; Fatty acids; Triglycerides;
Connective tissue growth factor induces tube formation and IL-8 production in first trimester human placental trophoblast cells
Keywords: CTGF; connective tissue growth factor; IL-8; interleukin-8; VEGF; vascular endothelial growth factor; ANGPTL4; angiopoietin-like protein 4; CTGF; Tube formation; IL-8; FABP4; HTR8/SVneo; Angiogenesis;
The SNPs in the promoter regions of the bovine FADS2 and FABP4 genes are associated with beef quality traits
Keywords: FADS2; FABP4; SNP; Promoter; BMS
miR-709 inhibits 3T3-L1 cell differentiation by targeting GSK3β of Wnt/β-catenin signaling
Keywords: PPARγ2; peroxisome proliferator-activated receptor γ 2; C/EBPα; CCAAT/enhancer binding protein α; FABP4; fatty acid binding protein-4; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; miR-709; Adipogenesis; GSK3β; β-Catenin signaling;
mRNA expression of genes regulating lipid metabolism in ringed seals (Pusa hispida) from differently polluted areas
Keywords: ACOX1; acyl-coenzyme A oxidase 1; ADIPOQ; adiponecin; CD36; cluster of differentiation 36; FABP4; fatty acid binding protein 4; NR; nuclear receptors; POPs; persistent organic pollutants; PPARα; peroxisome proliferator-activated receptor alpha; PPARβ; p
Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes
Keywords: 17-AAG; 17-allylamino-17-demethoxygeldanamycin; BCS; bovine calf serum; C/EBPα; CCAAT element binding protein α; FABP4; fatty acid-binding protein 4; FACS; fluorescence-activated cell sorting; FAS; fatty acid synthase; FBS; fetal bovine serum; Hsp90; he
Akt and ERK/Nrf2 activation by PUFA oxidation-derived aldehydes upregulates FABP4 expression in human macrophages
Keywords: FABP4; Nrf2; Aldehyde; Macrophages; Atherosclerosis;
Antiobesity effects of quercetin-rich onion peel extract on the differentiation of 3T3-L1 preadipocytes and the adipogenesis in high fat-fed rats
Keywords: OPE; onion peel extract; AP2; activating protein; CPT-1α; carnitine palmitoyltransferase-1 α; FABP4; fatty acid binding protein 4; FAS; fatty acid synthase; ACC; acetyl-CoA carboxylase; Onion peel extract; Quercetin; 3T3-L1; High-fat diet; Adipogenesis;
Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice
Keywords: Lymphangiogenesis; Lymphatic endothelial cell; WNT5A; ROR1; RYK; FDZ3; DKK2; FABP4; AChE; LGALS3BP; ENTPD1;
Lifestyle Changes Lower FABP4 Plasma Concentration in Patients With Cardiovascular Risk
Keywords: FABP4; Body weight loss; Physical activityFABP4; Pérdida de peso; Actividad físicaCV, cardiovascular; FABP4, adipocyte fatty acid-binding protein; PA, physical activity
Cambios de estilo de vida disminuyen las concentraciones plasmáticas de FABP4 en pacientes con riesgo cardiovascular
Keywords: FABP4; Pérdida de peso; Actividad físicaFABP4; Body weight loss; Physical activityAF, actividad física; CV, cardiovascular; FABP4, adipocyte fatty acid-binding protein
FABP4 predicts atherogenic dyslipidemia development. The PREDIMED study
Keywords: Atherogenic dyslipidemia; FABP4; Predictive marker; PREDIMED;
The role of serum adipocyte fatty acid-binding protein on the development of metabolic syndrome is independent of pro-inflammatory cytokines
Keywords: FABP4; Metabolic syndrome; Insulin resistance; Inflammation
Effects of long-term consumption of low doses of resveratrol on diet-induced mild hypercholesterolemia in pigs: a transcriptomic approach to disease prevention
Keywords: FABP4; Macrophages; Oxidized LDL; Metabolites; Glucuronide; Dihydroresveratrol; Grape extract
NAD(P)H:quinone oxidoreductase 1 activity reduces hypertrophy in 3T3-L1 adipocytes
Keywords: Nrf2; nuclear factor E2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; NQO1; NAD(P)H:quinine oxidoreductase 1; GSK-3β; glycogen synthase kinase-3β; GST; glutathione S-transferase, HO-1, heme oxygenase-1; ARE; antioxidant response element,
Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism
Keywords: MSC; mesenchymal stem cell; PPARγ; peroxisome proliferator-activated receptor-γ; FABP4; fatty acid-binding protein 4; C/EBPα; CCAAT/enhancer-binding protein-α; WAT; white adipose tissue; BAT; brown adipose tissue; Id2; inhibitor of DNA binding 2; TLE3
Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells
Keywords: L-PGDS; Lipocalin-type prostaglandin D2 synthase; MSCs; Mesenchymal stromal cells; PL; Platelet lysate; FCS; Fetal calf serum; PPARγ; Peroxisome proliferator-activated receptor gamma; CEBPα; CCAAT/enhancer binding protein alpha; FABP4; Fatty acid bindin
FABP4, función endotelial y grosor de la Ãntima-media carotÃdeo en pacientes con riesgo cardiovascular
Keywords: FABP4; Función endotelial; Diabetes tipo 2; Hiperemia reactiva; Riesgo cardiovascular; FABP4; Endothelial function; Type 2 diabetes; Reactive hyperemia; Cardiovascular risk;
Expression and function of fatty acid-binding protein 4 during mouse decidualization
Keywords: Uterus; embryo implantation; decidualization; Fabp4;
Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening
Keywords: FABP4; FABP3; Inhibitor; Selectivity; MD studies; Mutation;
Ras signalling regulates differentiation and UCP1 expression in models of brown adipogenesis
Keywords: AEBP1; AE-binding protein 1; C/EBP; CCAAT/enhancer-binding protein; CS; citrate synthase; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FABP4; fatty acid-binding protein 4; FBS; foetal bovi
Induction of gene encoding FABP4 in Pten-null keratinocytes
Keywords: Pten; FABP4; PPARγ; Sebaceous gland; Microarray
A novel polymorphism in the chicken adipocyte fatty acid-binding protein gene (FABP4) that alters ligand-binding and correlates with fatness
Keywords: AFABP; Chicken; Ligand-binding; Lipid; Polymorphism; Fatty acid; FABP4
Progression of human bone marrow stromal cells into both osteogenic and adipogenic lineages is differentially regulated by structural conformation of collagen I matrix via distinct signaling pathways
Keywords: BMSCs; bone marrow stromal cells; NC I; native collagen I matrix; DC I; denatured collagen I matrix; ERK; Extracellular signal-regulated kinase; p38; p38 mitogen-activated protein kinase; Raf or Raf-1; serine/threonine-specific kinase in ERK activating ca
Depot specific differences during adipogenesis of porcine stromal-vascular cells
Keywords: Adipocyte differentiation; Porcine; Depot origin; Gene expression; Subcutaneous; Visceral; Stromal-vascular cells; ACOX1; acyl-coenzyme A oxidase 1; APM1; adiponectin; CAT; catalase; C/EBP; CCAAT/enhancer-binding protein; CM; control medium; CPT1; carniti
The fatty acid binding protein-4 (FABP4) is a strong biomarker of metabolic syndrome and lipodystrophy in HIV-infected patients
Keywords: FABP4; HIV infection; Lipodystrophy; Metabolic syndrome; Metabolic biomarkers
Presence of fatty-acid-binding protein 4 expression in human epicardial adipose tissue in metabolic syndrome
Keywords: Ascending aorta; Epicardial adipose tissue; FABP4; Metabolic syndrome
Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients
Keywords: FABP4; Inflammation; Lipid oxidation; Metabolic syndrome; Type 2 diabetes
Fatty acid binding protein 4 in human skeletal muscle
Keywords: FABP3; FABP4; Fatty acid binding protein; Fat metabolism; Exercise; Gene expression; Muscle fiber types; Immunohistochemistry
FABP3 and FABP10 in Atlantic salmon (Salmo salar L.)- General effects of dietary fatty acid composition and life cycle variations
Keywords: Atlantic salmon; FABP; Fatty acids; Fatty acid oxidation; FABP1; FABP3; FABP4; FAPB10; Quantitative PCR