Treatment of the bone marrow failure in Fanconi anemia patients with danazol
Keywords: کم خونی Fanconi; Fanconi anemia; Danazol; Androgen; Bone marrow failure; Treatment
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Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
Keywords: کم خونی Fanconi; 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi
Incidence of Fanconi Anemia in Children with Congenital Thumb Anomalies Referred for Diepoxybutane Testing
Keywords: کم خونی Fanconi; Congenital; Fanconi anemia; radius; hypoplasia; thumb
Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes
Keywords: کم خونی Fanconi; α-LA; α-lipoic acid; 3-AT; 3-amino-1,2,4-triazole; 8OHdG; 8-hydroxydeoxyguanosine; ALC; acetyl-l-carnitine; BSA; bovine serum albumin; CDU; cyclohexyl-3-dodecyl urea; CHX; cycloheximide; DEB; 1,2:3,4-diepoxybutane; EH; epoxide hydrolase; FA; Fanconi Ane
New insights into the formation and resolution of ultra-fine anaphase bridges
Keywords: کم خونی Fanconi; BLM; Bloom's syndrome; Fanconi anemia; PICH; Anaphase bridges; Chromosome segregation
Bone Marrow Transplantation for Fanconi Anemia Using Fludarabine-Based Conditioning
Keywords: کم خونی Fanconi; Fanconi anemia; Allogeneic hematopoietic stem cell transplantation; Fludarabine
The phenotype of FancB-mutant mouse embryonic stem cells
Keywords: کم خونی Fanconi; Fanconi anemia; Interstrand crosslink; G2 arrest; Radial; FancD2; Rad51
Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation
Keywords: کم خونی Fanconi; DNA interstrand crosslinking; 6-Thioguanine; Ultraviolet A; Fanconi anemia;
FANCD2 but not FANCA promotes cellular resistance to type II topoisomerase poisons
Keywords: کم خونی Fanconi; Fanconi Anemia; FANCD2; FANCA; Etoposide
Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage
Keywords: کم خونی Fanconi; Fanconi anemia; ATM; DNA repair; Oxidative damage
Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway
Keywords: کم خونی Fanconi; Fanconi Anemia; MutS homologs; DNA damage response; Sensor;
Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex
Keywords: کم خونی Fanconi; Fanconi anemia; ICL repair; DNA replication; Genomic stability
Evidence for complete epistasis of null mutations in murine Fanconi anemia genes Fanca and Fancg
Keywords: کم خونی Fanconi; Fanconi anemia; Knockout mice; Crosslink repair; Fanca; Fancg
The role of stat1b in zebrafish hematopoiesis
Keywords: کم خونی Fanconi; Stat1α; Stat1β; Hematopoiesis; Myeloid; Fanconi anemia; Zebrafish
Multiple synchronous tumors in a child with Fanconi anemia
Keywords: کم خونی Fanconi; Synchronous tumors; Fanconi anemia; Cancer predisposition syndrome; Wilms tumor; Neuroblastoma
Targeting DNA repair pathways in AML
Keywords: کم خونی Fanconi; acute myeloid leukemia; AML; DNA repair pathway; Fanconi anemia; FA; poly-ADP-ribose polymerase (PARP) inhibitors; synthetic lethality
FANCJ: Solving problems in DNA replication
Keywords: کم خونی Fanconi; Fanconi anemia; Helicase; FANCJ; DNA repair; DNA replication;
Fanconi Anemia pathway heterogeneity revealed by cisplatin and oxaliplatin treatments
Keywords: کم خونی Fanconi; Fanconi Anemia; FANCD2; FANCA; Platinum drugs
The involvement of FANCM, FANCI, and checkpoint proteins in the interstrand DNA crosslink repair pathway is conserved in C. elegans
Keywords: کم خونی Fanconi; Cell cycle checkpoint; Fanconi anemia; FANCM; FANCI; Nuclear foci
Malignant pleural mesothelioma: Genome-wide expression patterns reflecting general resistance mechanisms and a proposal of novel targets
Keywords: کم خونی Fanconi; Chemo-resistance; DNA repair; Drug target; Fanconi anemia; Homologous recombination; Microarray; Radiation resistance
The FANCM family of DNA helicases/translocases
Keywords: کم خونی Fanconi; FANCM; Mph1; Fml1; Hef; Homologous recombination; Fanconi Anemia;
Synchronous multifocal HPV-related neoplasm involving both the genital tract and the head-and-neck area: A case report of Fanconi anemia
Keywords: کم خونی Fanconi; Human papillomavirus; Fanconi anemia; Genital tract cancer; Head-and-neck cancer; Radiosensitivity
Monoubiquitylation in the Fanconi anemia DNA damage response pathway
Keywords: کم خونی Fanconi; Fanconi anemia; FA pathway; FA core complex; Ubiquitin; Monoubiquitylation
Molecular profiles of hereditary epithelial ovarian cancers and their implications for the biology of this disease
Keywords: کم خونی Fanconi; BRCA1; BRCA2; Ovarian cancer; Breast cancer; Microarray; Fanconi anemia
Knockdown of αII spectrin in normal human cells by siRNA leads to chromosomal instability and decreased DNA interstrand cross-link repair
Keywords: کم خونی Fanconi; α-Spectrin; siRNA knockdown; Chromosomal aberrations; DNA interstrand cross-links; Damage-induced nuclear foci; XPF; DNA repair; Fanconi anemia
Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: Implications for alcohol-related carcinogenesis
Keywords: کم خونی Fanconi; Fanconi anemia; Breast cancer; Esophagus; Alcohol
FANCM–FAAP24 and FANCJ: FA proteins that metabolize DNA
Keywords: کم خونی Fanconi; Fanconi anemia; FANCM; FAAP24; FANCJ; Helicase; DNA repair
Identification and analysis of new proteins involved in the DNA damage response network of Fanconi anemia and Bloom syndrome
Keywords: کم خونی Fanconi; BLM; Fanconi anemia; Topoisomerase 3a; RMI
Clinical Radiation Sensitivity With DNA Repair Disorders: An Overview
Keywords: کم خونی Fanconi; Ataxia-telangiectasia; radiation sensitivity; radiotherapy; DNA repair disorders; adverse reactions; Fanconi anemia;
The genetic and molecular basis of Fanconi anemia
Keywords: کم خونی Fanconi; Fanconi anemia; DNA cross-linking agents; Replication; Genomic instability; DNA repair
Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia
Keywords: کم خونی Fanconi; Fanconi anemia; HSC; Gene therapy; Bone marrow failure
The Fanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line
Keywords: کم خونی Fanconi; Fanconi anemia; Interstrand crosslink; DNA repair; Translesion synthesis; Homologous recombination; DT40 cell line
C. elegans: A model of Fanconi anemia and ICL repair
Keywords: کم خونی Fanconi; Fanconi anemia; ICL repair; Genome stability; C. elegans
The Fanconi anemia protein interaction network: Casting a wide net
Keywords: کم خونی Fanconi; Fanconi anemia; DNA repair; Chromosome instability; Homologous recombination; Translesion DNA synthesis
Therapeutic options for triple-negative breast cancers with defective homologous recombination
Keywords: کم خونی Fanconi; ABC; ATP-binding cassette; APC; Adenomatous, polyposis coli; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3-related; BER; base-excision repair; BRCA1; Breast cancer susceptibility gene 1; BRCA2; Breast cancer susceptibility gene 2; CGH; Comparative
Fanconi Anemia
Keywords: کم خونی Fanconi; Fanconi anemia; Bone marrow failure; Genomic instability; DNA damage and repair; Oxidative stress; Monobiquitylation; Cytokines; BRCA1/2
Neoadjuvant Chemotherapy with Reduced-Dose Carboplatin and Gemcitabine for Non-small Cell Lung Cancer in a Patient with Fanconi Anemia
Keywords: کم خونی Fanconi; Fanconi anemia; Non-small cell lung cancer; Neoadjuvant; Carboplatin; Gemcitabine
Second Stem Cell Transplantation in Patients with Fanconi Anemia Using Antithymocyte Globulin Alone for Conditioning
Keywords: کم خونی Fanconi; Fanconi anemia; Second stem cell transplantation; Antithymocyte globulins; Graft failure
Cáncer de vulva recidivante en una paciente con anemia de Fanconi
Keywords: کم خونی Fanconi; Anemia de Fanconi; Cáncer de vulva; Leucemia mieloblástica; Fanconi anemia; Vulvar cancer; Myeloid leukemia;
Differential expression of TP53 associated genes in Fanconi anemia cells after mitomycin C and hydroxyurea treatment
Keywords: کم خونی Fanconi; Fanconi anemia; Hydroxyurea; Mitomycin C; TP53; Gene expression; Cell cycle arrest; Apoptosis;
HLA-Matched Sibling Hematopoietic Stem Cell Transplantation for Fanconi Anemia: Comparison of Irradiation and Nonirradiation Containing Conditioning Regimens
Keywords: کم خونی Fanconi; Fanconi anemia; Matched sibling donor; Conditioning regimen; Survival; Graft-versus-host disease
Mammalian SNM1 is required for genome stability
Keywords: کم خونی Fanconi; SNM1; Genome stability; Radials; Interstrand crosslink repair; Fanconi anemia
ERCC1 is required for FANCD2 focus formation
Keywords: کم خونی Fanconi; Fanconi anemia; Interstrand crosslink; ERCC1; Double strand break
Spectrum of mutational events in the absence of DOG-1/FANCJ in Caenorhabditis elegans
Keywords: کم خونی Fanconi; Dog-1 mutator; Fanconi anemia; FANCJ; Genome instability; Chromosome instability (CIN); Chromosomal rearrangement; Lethal analysis;
Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways
Keywords: کم خونی Fanconi; ICL repair; Caenorhabditis elegans; Fanconi anemia; Checkpoints; RAD-51
Endogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation
Keywords: کم خونی Fanconi; hSNM1B; SNM1B; Apollo; DCLRE1B; SNM1; pso2; ARTEMIS; TRF2; Telomere; ATM; ATM autophosphorylation; Fanconi Anemia; DNA-repair; Yeast two hybrid; siRNA; p53; Nuclear foci; DNA damage response;
The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly
Keywords: کم خونی Fanconi; Fanconi anemia; Translesion synthesis; Mutagenesis; DNA repair
MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair
Keywords: کم خونی Fanconi; FA, fanconi anemia; MEN1, multiple endocrine neoplasia type I; ICLs, interstrand crosslinksDrosophila; supF; DNA repair; Interstrand crosslinks; Multiple endocrine neoplasia type 1; Fanconi anemia
Variation in cisplatinum sensitivity is not associated with Fanconi Anemia/BRCA pathway inactivation in head and neck squamous cell carcinoma cell lines
Keywords: کم خونی Fanconi; Fanconi anemia; FANCF; FANCD2; Mono-ubiquitination; Cisplatinum; Squamous cell carcinoma
HLA-Matched Related Donor Hematopoietic Cell Transplantation in 43 Patients with Fanconi Anemia Conditioned with 60 mg/kg of Cyclophosphamide
Keywords: کم خونی Fanconi; Fanconi anemia; HLA-matched marrow graft; Low-dose cyclophosphamide