Keywords: متابولیسم فولات; Leishmania; Folate metabolism; Gene inactivation; Serine
مقالات ISI متابولیسم فولات (ترجمه نشده)
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Keywords: متابولیسم فولات; Folate metabolism; Colorectal cancer; Pharmacogenetics;
Keywords: متابولیسم فولات; MTHFR polymorphism; Acute lymphoblastic leukemia; Folate metabolism
Keywords: متابولیسم فولات; Chemoresistance; Thymidylate synthase; Anticancer drugs; Folate metabolism; Folate dependent enzymes; Pathways perturbations; Proteomic; Personalized Medicine; Clinical trials; Holistic/reductionistic approach
Keywords: متابولیسم فولات; FDH; 10-formyltetrahydrofolate dehydrogenase; THF; tetrahydrofolate; dpf; day-post-fertilization; hpf; hour-post-fertilization; MO; morpholino oligonucleotide; WISH; whole-mount in situ hybridization; FDH-N-ter; FDH N-terminal domain; Zebrafish; ROS; Cell
Analysis of occurrence of MTRR gene polymorphism in Down syndrome and other intellectually disabled children
Keywords: متابولیسم فولات; Intellectual disability; Down syndrome; MTRR c.66Aâ¯>â¯G; PCR-RFLP analysis; Folate metabolism; Methionine synthase reductase; ID; Intellectual Disability; WHO; World Health Organization; IQ; Intelligence Quotient; DS; Down Syndrome; MTRR; 5-Methyltetra
Molecular cloning and characterization of C1 tetrahydrofolate (C1-THF) synthase in Bombyx mori, silkworm
Keywords: متابولیسم فولات; THF; C1 tetrahydrofolate; silkworm cytoplasmic C1-THF synthase; BmC1-THF synthase; ORF; open reading frame; qRT-PCR; quantitative real-time PCR; THF_DHG_CYH; methylenetetrahydrofolate dehydrogenase; THF_DHG_CYH_C; methenyltetrahydrofolate cyclohydrolase;
Transcriptome analysis of Cyrtotrachelus buqueti in two cities in China
Keywords: متابولیسم فولات; RT-qPCR; quantitative real-time PCR; RPKM; reads per kilobase million mapped reads; DEGs; differentially expressed genes; FDR; false discovery rate; Cyrtotrachelus buqueti; Transcriptome analysis; Quantitative distribution; Ribosome; Folate metabolism; He
Association of RFC1 A80G gene polymorphism with advanced maternal age in risk of Down syndrome
Keywords: متابولیسم فولات; DS; Down syndrome; NDJ; nondisjunction; MTHFR; methylenetetrahydrofolate reductase; MTR; 5-methyltetrahydrofolate-homocysteine methyltransferase; MTRR; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase; RFC1; reduced folate carrier 1; IHEC
Computational analysis for the determination of deleterious nsSNPs in human MTHFD1 gene
Keywords: متابولیسم فولات; In silico analysis; Human MTHFD1 gene polymorphism; Single nucleotide polymorphisms; Folate metabolism; MTHFD15; 10-methylenetetrahydrofolate dehydrogenase 1; SIFT; sorting intolerant from tolerant; SNPs&GO; single nucleotide polymorphisms and gene ontolo
Folates as adjuvants to anticancer agents: Chemical rationale and mechanism of action
Keywords: متابولیسم فولات; Folate metabolism; Leucovorin; Mechanism of action; 5-Fluorouracil, [6R]-5,10-methylene-tetrahydrofolate;
Association between MTHFD1 polymorphisms and neural tube defect susceptibility
Keywords: متابولیسم فولات; Neural tube defects; Methylenetetrahydrofolate dehydrogenase (MTHFD1); 1958G > A; Polymorphism; Folate metabolism; Association
MTHFR C677T and A1298C polymorphisms and risk of nonsyndromic orofacial clefts in a south Indian population
Keywords: متابولیسم فولات; Folate metabolism; MTHFR; Orofacial cleft; SNP;
Lessons from the one-carbon metabolism: passing it along to the next generation
Keywords: متابولیسم فولات; assisted reproduction; folate metabolism; fetal programming; one-carbon metabolism; placenta; transgenerational epigenetic inheritance
Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk
Keywords: متابولیسم فولات; Head and neck cancer; Folate metabolism; Folate gane polymorphisms; Alcohol habits; Tobacco habits
Down Syndrome in India-Diagnosis, Screening, and Prenatal Diagnosis
Keywords: متابولیسم فولات; Down syndrome; Cytogenetic studies; Folate metabolism; Screening and prenatal diagnosis; Noninvasive prenatal diagnosis; Future therapies;
Genetic variation in folate metabolism is not associated with cognitive functioning or mood in healthy adults
Keywords: متابولیسم فولات; APOE; apolipoprotein E; CST; Concept Shifting Test; FACIT; Folic Acid and Carotid Intima-Media Thickness study; LDST; Letter-Digit Substitution Test; MAAS; Maastricht Aging Study; MTHFR; 5,10-methylenetetrahydrofolate reductase; SCLdep; depression subscal
Polymorphisms in genes involved in folate metabolism and orofacial clefts
Keywords: متابولیسم فولات; Folate metabolism; Orofacial cleft; SNP; Genetics;
Breast cancer risk, dietary intake, and methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms
Keywords: متابولیسم فولات; MTHFR; Diet intake; Folate metabolism; SNP; Breast cancer
Depleted folate pool and dysfunctional mitochondria associated with defective mitochondrial folate proteins sensitize Chinese ovary cell mutants to tert-butylhydroperoxide-induced oxidative stress and apoptosis
Keywords: متابولیسم فولات; Folate metabolism; Apoptosis; Oxidative stress; Respiratory dysfunction; Chinese hamster ovary cell mutants
Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: Results from the Malaysia-Singapore ALL Study Group
Keywords: متابولیسم فولات; Childhood ALL; Genetic epidemiology; Polymorphism; Gender effect; NQO1; Folate metabolism; Malay
Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition
Keywords: متابولیسم فولات; Antifolate inhibitor studies; Biphasic kinetics; Folate metabolism; Methotrexate; Phosphinate analogues of folate; Substrate specificity; DHF; dihydrofolate; DHFR; dihydrofolate reductase; DHFS; dihydrofolate synthase; DHP; dihydropteroate; DHPS; dihydrop
5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887
Keywords: متابولیسم فولات; Folate metabolism; Methenyltetrahydrofolate synthetase; Purine biosynthesis; LY309887; Antifolate; Glycinamide ribonucleotide formyltransferase
Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target
Keywords: متابولیسم فولات; SHMT; serine hydroxymethyltransferase; PfSHMT; Plasmodium falciparum serine hydroxymethyltransferase; Pv; P. vivax; dTMP; deoxythymidine 5â²-monophosphate; H4folate; (6RS)-tetrahydrofolate; CH2-H4folate; 5,10-methylenetetrahydrofolate; CH3-H4folate; 5-me
The complex relationship between folate/homocysteine metabolism and risk of Down syndrome
Keywords: متابولیسم فولات; Down syndrome (DS); Folate metabolism; Homocysteine (Hcy); Gene polymorphisms; Epigenetics; MTHFR; MTRR; MTR; RFC1; CBS
Folate pathway genetic polymorphisms and susceptibility of central nervous system tumors in Thai children
Keywords: متابولیسم فولات; Polymorphisms; Folate pathway; Central nervous system tumors; Thai children; Thailand; Pediatric brain tumors; Case-control study; Folate metabolism
Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice
Keywords: متابولیسم فولات; Folate metabolism; Folate transport; Tumorigenesis; Intestinal neoplasia
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase
Keywords: متابولیسم فولات; Homocysteine; Hyperhomocyst(e)inemia; Folate metabolism; Gene trap; Methionine synthase reductase; Methionine metabolism; Hypomethioninemia; Methyl trap; S-Adenosylmethionine; S-Adenosylhomocysteine
Stage specific gene expression and cellular localization of two isoforms of the serine hydroxymethyltransferase in the protozoan parasite Leishmania
Keywords: متابولیسم فولات; Leishmania; Folate metabolism; Mitochondria; Drug target
Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets
Keywords: متابولیسم فولات; Folate metabolism; Purine; Pyrimidine; Enzyme inhibition; Antifolates; HFPN; hybrid functional petri nets; GON; genomic object net; DHF; dihydrofolate; THF; tetrahydrofolate; 5-CHO-THF; 5-formyl-THF; 5; 10-CH2-THF; 5; 10-methylene-THF; MTX; methotrexate;
Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele
Keywords: متابولیسم فولات; Migraine genetics; Folate metabolism; Migraine; Genetic association study; Thymidylate synthase; Methenyltetrahydrofolate cyclohydrolase formyltetrahydrofolate synthase; Methylenetetrahydrofolate reductase;
Arylamine N-acetyltransferase I
Keywords: متابولیسم فولات; Arylamine N-acetyltransferase; Catalytic triad; Folate metabolism; Polymorphism; Ubiquitination
Toxoplasma gondii is capable of exogenous folate transport
Keywords: متابولیسم فولات; AISS; artificial intracellular salt solution; DHFR-TS; dihydrofolate reductase-thymidylate synthase; F-MTX; fluorescein-methotrexate; HFF; human foreskin fibroblast; MTX; methotrexate; MW; molecular weight; MWCO; molecular weight cut off; PBS; phosphate-b
Polymorphisms in folate metabolic genes and lung cancer risk in Xuan Wei, China
Keywords: متابولیسم فولات; Folate metabolism; Single nucleotide polymorphism; Lung cancer; Polycyclic aromatic hydrocarbon; Haplotype;
Exploring the folate pathway in Plasmodium falciparum
Keywords: متابولیسم فولات; Antifolate drugs; Drug resistance; Folate metabolism; Folate salvage; Gene disruption; Metabolic labelling;