Keywords: AMPK; AMP-activated protein kinase; ARF6; ADP-ribosylation factor 6; AKT; protein kinase B; BBB; blood brain barrier; bFGF; b-fibroblast growth factors; b-FGFR; b-fibroblast growth factors receptor; ccRCC; clear cell renal cell carcinoma; ECs; endothelial
مقالات ISI (ترجمه نشده)
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Keywords: FoxM1; forkhead box protein M1; STAT3; signal transducer and activator of transcription 3; SOX2; SRY-related high-mobility-group (HMG)-box protein-2;
Keywords: Adipose tissue; Cancer associated adipocytes; FABP4; FABP5; Lipid metabolism; ADF; adipocyte-derived fibroblasts; BAT; brown adipose tissue; BMAT; bone marrow adipose tissue; BMI; body mass index; CAA; cancer-associated adipocytes; CAF; cancer-associated
Keywords: 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
Keywords: Aurkb; aurora kinase B; Ccna2; cyclin A2; Ccnb1; cyclin B1; Ccnd1; cyclin D1; Ccnd2; cyclin D2; Ccnd3; cyclin D3; Cdc20; cell division cycle 20; Cenpa; centromere protein A; Cenpb; centromere protein B; Cenpf; centromere protein F; Foxm1; forkhead transcr
Keywords: Skin; TGFβ; Inflammation; Extracellular matrix; Therapy; ACE; angiotensin-converting enzyme; ACE2; angiotensin-converting enzyme 2; AT1; angiotensin II receptor type 1; ADAM; a disintegrin and metalloproteinase family sheddase; AT2; angiotensin II recept
Keywords: TUNEL; terminal deoxynucleotidyl transferase dUTP nick-end labeling; ELISA; enzyme-linked immunosorbent assay; DNA; deoxyribonucleic acid; TNFα; tumor necrosis factor-alpha; Foxa2; forkhead box protein A2; HNF6; hepatocyte nuclear factor 6; C/EBPα; CCAA
Keywords: α-TOS; α-tocopheryl succinate; BAP1; BRCA1 associated protein-1; BRCA1; breast cancer susceptibility gene 1; CDK4; cyclin-dependent kinase 4; CEA; carcinoembryonic antigen; CSC(s); cancer stem(-like) cell(s); CTGF; connective tissue growth factor (CCN2)
Keywords: Pubchem CID: 444795; Aldh1a2; aldehyde dehydrogenase family 1 member A2; Cdk1; Cyclin-dependent kinase 1, Cdc25, cell division cycle 25; ChIP-seq; chromatin immunoprecipitation followed by next generation sequencing; Crabp1; cellular retinoic acid binding
Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody
Keywords: ANOVA; analysis of variance; BrdU; 5-bromo-2â²-deoxyuridine; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN2A; CDKN inhibitor 2A; CE; coefficient of error; CV; coefficient of variation; D; day; E2F1; E2F transcription factor 1; FOXM1; Forkhead box pr
FOXM1 promotes proliferation in human hepatocellular carcinoma cells by transcriptional activation of CCNB1
Keywords: Human hepatocellular carcinoma; Cell proliferation; Transcriptional regulation; Cell cycle; FOXM1;
SALL4 suppresses reactive oxygen species in pancreatic ductal adenocarcinoma phenotype via FoxM1/Prx III axis
Keywords: SALL4; Pancreatic ductal adenocarcinoma; Metastasis; FoxM1; Peroxiredoxin III;
Long non-coding RNA LINC00339 facilitates the tumorigenesis of non-small cell lung cancer by sponging miR-145 through targeting FOXM1
Keywords: Non-small cell lung cancer; LINC00339; miR-145; FOXM1;
Down-regulation of lncRNA MEG3 promotes endothelial differentiation of bone marrow derived mesenchymal stem cells in repairing erectile dysfunction
Keywords: Erectile dysfunction; Bone marrow derived mesenchymal stem cells; MEG3; FOXM1;
Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment
Keywords: Inflammation-associated cancer; Ubiquitin-proteasome system (UPS); Small ubiquitin-like modifier (SUMO); Tumor microenvironment; Cytokine profile; Transcription factors; 15d-PGJ2; 15-Deoxy-Delta-12,14-prostaglandin J2; AR; androgen receptor; Ala; alanine;
Scutellaria: Debates on the anticancer property
Keywords: Bcl-2; B-cell lymphoma 2; 5-FU; 5-Fluorouracil; TGF-β1; transforming growth factor beta 1; PTEN; phosphatase and tensin homolog; HIF-1α; hypoxia-inducible factor 1-alpha; MAPK; mitogen-activated protein kinase; CRC; cyclic redundancy check; SHH; sonic h
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma
Keywords: CIP2A; FoxM1; Hepatocellular carcinoma; Cell cycle; Cellular senescence;
MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway
Keywords: GC; Gastric cancer; FAT4; Protocadherin Fat 4; LATS2; Large tumor suppressors 2; CDX2; Caudal-related homeobox transcription factor; FOXM1; Fork head box M1; CTGF; Connective tissue growth factor; CYR61; Cysteine-rich angiogenic inducer 61; RUNX3; Runt-re
Elevated O-GlcNAcylation stabilizes FOXM1 by its reduced degradation through GSK-3β inactivation in a human gastric carcinoma cell line, MKN45 cells
Keywords: O-GlcNAcylation; Ubiquitination; FOXM1; GSK-3β;
Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis
Keywords: Fatty acids; Cancer; Lipid metabolism; FOXO3; FOXM1; AKT/PI3K pathway; AKT; protein kinase B; AMPK; adenosine monophosphate-activated-activated protein kinase; APN; adiponectin; CoA; coenzyme A; CPT1; carnitine palmitoyltransferase 1; DHA; docosahexaenoic
Crosstalk between Nrf2 and YAP contributes to maintaining the antioxidant potential and chemoresistance in bladder cancer
Keywords: Glutathione; Nrf2; YAP; FOXM1; Chemoresistance; Bladder cancer cells;
FoxM1: Repurposing an oncogene as a biomarker
Keywords: FoxM1; Oncogene; Biomarker; Cancer; Prognosis; Diagnosis; Therapy;
Untying the knot of transcription factor druggability: Molecular modeling study of FOXM1 inhibitors
Keywords: FOXM1; Thiostrepton; Thiazolidinediones; Troglitazone;
Mechanism of N6-methyladenosine modification and its emerging role in cancer
Keywords: ADAR; adenosine deaminase, RNA specific; α-KG; α-ketoglutarate; ALKBH5; alkB homologue 5; AML; acute myeloid leukemia; CDS; coding sequences; CLIP; cross-linking and immunoprecipitation; eIF3; eukaryotic initiation factor 3; ESC; embryonic stem cell; FO
Members of FOX family could be drug targets of cancers
Keywords: FOX; Forkhead box; BLBC; basal-like breast cancer; HCC; Hepatocellular carcinoma; NSCLC; Non-small-cell lung cancer; ALL; Acute lymphoblastic leukemia; CRC; Colorectal cancer; TNBC; Triple negative breast cancer; CSC; Cancer stem cell; ESC; Embryonic stem
ReviewClinicopathological and prognostic significance of FoxM1 in gastric cancer: A meta-analysis
Keywords: Prognosis; Clinical parameters; FoxM1; Gastric cancer; Meta-analysis;
Phosphorylation of transcriptional regulators in the retinoblastoma protein pathway by UL97, the viral cyclin-dependent kinase encoded by human cytomegalovirus
Keywords: Human cytomegalovirus; Viral CDK; UL97; Cell cycle; Rb pathway; E2F3; DREAM complex; LIN52; FoxM1;
ADAM-17 expression is enhanced by FoxM1 and is a poor prognostic sign in gastric carcinoma
Keywords: Gastric carcinoma; FoxM1; ADAMs; Prognosis;
CRY2 is suppressed by FOXM1 mediated promoter hypermethylation in breast cancer
Keywords: CRY2; FOXM1; Methylation; Breast cancer; Prognosis;
MELK is an oncogenic kinase essential for early hepatocellular carcinoma recurrence
Keywords: Oncogenic kinase; MELK; Hepatocellular carcinoma; Recurrence; FOXM1;
Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells
Keywords: Head and neck cancer; Dihydroartemisinin; Ferroptosis; Antitumor; Cell cycle; ART; artemisinin; BAX; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CDC2; cell division cycle protein 2 (also known as cyclin-dependent kinase 1); DFO; deferoxamine; DH
Cancer TARGETases: DSB repair as a pharmacological target
Keywords: DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel
Small molecule inhibition of FOXM1: How to bring a novel compound into genomic context
Keywords: Small molecule inhibition; RNA-Seq; Genomics; Transcription; FOXM1
Targeting FoxM1 transcription factor in T-cell acute lymphoblastic leukemia cell line
Keywords: Dexamethasone; FoxM1; Jurkat cells; Siomycin A; T-cell acute lymphoblastic leukemia
Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression
Keywords: Glioma; Plumbagin; Proliferation; Apoptosis; FOXM1
In silico investigation of FOXM1 binding and novel inhibitors in epithelial ovarian cancer
Keywords: In silico; FOXM1; Ovarian cancer; Small molecule inhibitors; Thiazole antibiotics;
Research ArticleEssential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features
Keywords: FoxM1; Ras-driven liver cancer; Liver cancer cells with stem cell features;
The FOXM1-induced resistance to oxaliplatin is partially mediated by its novel target gene Mcl-1 in gastric cancer cells
Keywords: FOXM1; Mcl-1; Apoptosis; Oxaliplatin;
Original ArticleBreast tissue-based microRNA panel highlights microRNA-23a and selected target genes as putative biomarkers for breast cancer
Keywords: BC; breast cancer; BMI; body mass index; ER; estrogen receptor; FOXM1; forkhead box m; Her-2 neu; human epidermal growth factor receptor 2; HRG; histidine-rich glycoprotein; HT; hormonal therapy; IDC; invasive duct carcinoma; ILC; invasive lobular carcino
Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition
Keywords: Methylseleninic acid (PubChem CID: 161597); Sodium selenite (PubChem CID: 24934); Cisplatin (PubChem CID: 441203); LY294002 (PubChem CID: 3973); MSA; methylseleninic acid; Se; selenium; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; ROS; reactiv
Original ResearchFull Report: Basic and Translational-Alimentary TractFOXM1-Induced PRX3 Regulates Stemness and Survival of Colon Cancer Cells via Maintenance of Mitochondrial Function
Keywords: ROS; Colon Cancer; Tumor Progression; Metastatic; ATP; adenosine triphosphate; CSC; cancer stem cell; FoxM1; forkhead box protein M1; 5-FU; 5-fluorouracil; OXPHOS; oxidative phosphorylation; Prx3; peroxiredoxin 3; ROS; reactive oxygen species; shPrx3; sho
Silibinin-induced glioma cell apoptosis by PI3K-mediated but Akt-independent downregulation of FoxM1 expression
Keywords: FoxM1; Silibinin; PI3K; Akt; apoptosis;
FOXM1 targets XIAP and Survivin to modulate breast cancer survival and chemoresistance
Keywords: ChIP; chromatin immunoprecipitation; FHRE; forkhead responsive elements; FISH; fluorescence in situ hybridization; FOX; forkhead box; HR; hormone receptor; IAP; inhibitor of apoptosis protein; IHC; immunohistochemistry; MTT; 3-(4,5-dimethylthiazlol-2-yl)-
Over-expression of FoxM1 is associated with adverse prognosis and FLT3-ITD in acute myeloid leukemia
Keywords: FoxM1; Acute myeloid leukemia; Prognosis; AML therapy;
miR-370 targeted FoxM1 functions as a tumor suppressor in laryngeal squamous cell carcinoma (LSCC)
Keywords: Laryngeal squamous cell carcinoma; MiR-370; FoxM1; Cell proliferation
Role of Frizzled6 in the molecular mechanism of beta-carotene action in the lung
Keywords: BC; β-carotene; BCMO1; beta-carotene 15,15â²-monooxygenase 1; Fzd6; frizzled homologue 6; Cthrc1; collagen triple helix repeat containing 1; GO; Gene Ontology; DAVID; Database for Annotation Visualization and Integrated Discovery; DO; Disease Ontology;
FOXM1: An emerging master regulator of DNA damage response and genotoxic agent resistance
Keywords: FOXM1; DNA damage; Transcriptional targets; Cancer; Drug resistance;
FOXM1: A key oncofoetal transcription factor in health and disease
Keywords: FOXM1; Transcription factor; Oncofoetal protein; Cancer; Development;
Down-regulation of FoxM1 leads to the inhibition of the epithelial-mesenchymal transition in gastric cancer cells
Keywords: FoxM1; epithelial-mesenchymal transition; migration; invasion